MarianneEwertz, MD, DMSci
Marianne Ewertzis Clinical Professor at the University of Southern Denmark and Senior Consultant at the Department of Oncology, Odense University Hospital (OUH),Denmark.
Dr. Ewertzobtained her MD at the University of Copenhagen in 1980. She is a board certified specialist in Oncology (1997) and defended her doctorial thesis: “Breast cancer in Denmark. Incidence, risk factors and characteristics of survival” at the University of Copenhagen in 1993.
Herprimary research interests include breast cancer, clinical epidemiology, and late effects of cancer treatment. She was the head of the Clinical Research Unit at AalborgHospital for 8 years and has extensive experience in conducting clinical trials.
She has 100+ publications in journals such as Lancet, Journal of Clinical Oncology, Journal of the National Cancer Institute, British Journal of Cancer, and Breast Cancer Research and Treatment.
Dr. Ewertz is a member of the Executive Group and the Steering Committee of the Early Breast Cancer Trialists´ Collaborative Group (EBCTCG), the Board and Radiotherapy Committee of the Danish Breast Cancer Collaborative Group (DBCG), and the Scientific Committee of the Danish Cancer Society.
Selected publications 2008-2012
Ewertz M, Kempel MM, Düring M, Jensen M, Andersson M, Christiansen P, Kroman N, Rasmussen BB, Overgaard M. Breast conserving treatment in Denmark, 1989-1998. A nationwide population-based study of the Danish Breast Cancer Co-operative Group. Acta Oncol 2008; 47: 682-90.
Ejlertsen B, Jensen M-J, Mouridsen HT, Andersen J, Cold S, Jakobsen E, Kamby C, Sørensen PG, Ewertz M. DBCG trial 89B comparing adjuvant CMF and ovarian ablation: similar outcome for elible but non-enrolled and randomized breast cancer patients. Acta Oncol 2008; 47: 709-17.
Kristensen B, Ejlertsen B, Mouridsen HT, Jensen M, Andersen J, Bjerrregaard B, Cold S, Edlund P, Ewertz M, Kamby C, Lindman H, Nordenskjöld B, Bergh J. Bisphosphonate treatment in primary breast cancer: Results from a randomized comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer. Acta Oncol 2008; 47: 740-46.
Debess J, Ostergaard Riis J, Pedersen L, Ewertz M. Cognitive function and quality of life after surgery for early breast cancer in North Jutland, Denmark. Acta Oncol 2009; 48: 532-540.
Ejlertsen B, Jensen M-J, Rank F, Rasmussen BB, Christiansen P, Kroman N, Ewertz Kvistgaard M, Overgaard M, Toftdahl DB, Mouridsen HT. Population-based study of peritumoral lymphovascular invasion and outcome among patients with operable breast cancer. J Natl Cancer Inst 2009; 101(10): 729-35.
Gärtner R, Jensen M-J, Nielsen J, Ewertz M, Kroman N, Kehlet N. Prevalence of and Factors Associated with Persistent Pain Following Breast Cancer Surgery. JAMA 2009; 302 (18): 1985-1992.
Witt PM, Christensen JH, Schmidt EB, Dethlevsen C, Tjønneland A, Ewertz M. Marine n-3 polyunsaturated fatty acids in adipose tissue and breast cancer risk: a case-cohort study from Denmark. Cancer Causes and Control 2009; 20: 1715-1721.
Debess J, Riis JO, Engebjerg MC, Ewertz M. Cognitive function after adjuvant chemotherapy for early breast cancer: a population based-longitudinal study. Breast Cancer Res Treat 2010; 121(1): 91-100.
Gärtner R, Jensen M-J, Kronborg L, Ewertz M, Kehlet N, Kroman N. Self-reported arm-lymphedema an functional impairment after breast cancer treatment – A nationwide study of prevalence and associated factors. Breast. 2010 Dec;19(6):506-15.
Jensen JD, Laenkholm AV, Knoop A, Ewertz M, Bandaru R, Weihua L, Hackl W, Barrett JC, Gardner H. PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer. Clin Cancer Res. 2010; 17(4): 667-77.
Ewertz M, JensenMB, Gunnarsdóttir KÁ, Højris I, Jakobsen EH, Nielsen D, Stenbygaard LE, Tange UB, Cold S. Effect of obesity on prognosis after early-stage breast cancer. J Clin Oncol. 2011;29(1):25-31.
McGale P, Darby SD, Hall P, Adolfsson J, Bengtsson N-O, Bennet AM, Fornander T, Gigante B, Jensen M-B, Peto R, Rahimi K, Taylor CW, Ewertz M. Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden. Radiother Oncol 2011; 100(2): 167-75.
Taylor CW, Brønnum D, Darby SD, Gagliardi G, Hall P, Jensen M-B, McGale P, Nisbet A, Ewertz M. Cardiac dose estimates from Danish and Swedish breast cancer radiotherapy during 1977-2001. Radiother Oncol 2011; 100(2): 176-83.
Christiansen P, Bjerre K, Ejlertsen B, Jensen M-B, Rasmussen BB, Lænkholm AV, Kroman N, Ewertz M, Offersen B, Toftdahl DB, Møller S, Mouridsen HT. Mortality rates among early-stage hormone receptor-positive breast cancer patients: A population-based cohort study in Denmark. JNCI 2011; 103(18): 1363-72.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Darby S, McGale P, Correa C, Taylor C, Arriagada R, Clarke M, Cutter D, Davies C, Ewertz M, Godwin J, Gray R, Pierce L, Whelan T, Wang Y, Peto R. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011 Nov 12; 378(9804): 1707-16.
Dupont Jensen J, Knoop A, Ewertz M, Lænkholm A-V. ER, HER2, and TOP2A expression in primary tumor, synchronous axillary nodes, and asynchronous metastases in breast cancer. Breast Cancer Res Treat 2012; 132(2): 511-21.
Jensen JD, Knoop A, Laenkholm AV, Grauslund M, JensenMB, Santoni-Rugiu E, Andersson M, Ewertz M. PIK3CA mutations, PTEN, and pHER2 expression and impact on outcome in HER2-positive early-stage breast cancer patients treated with adjuvant chemotherapy and trastuzumab..Ann Oncol. 2012; 23(8): 2034-42.
Land LH, Dalton SO, JensenMB, Ewertz M. Impact of comorbidity on mortality: a cohort study of 62,591 Danish women diagnosed with early breast cancer, 1990-2008. Breast Cancer Res Treat. 2012; 131(3); 1013-20.
Bigaard J, Stahlberg C, Jensen MB, Ewertz M, Kroman N. Breast cancer incidence by estrogen receptor status in Denmark from 1996 to 2007. Breast Cancer Res Treat 2012, Sept. 30 [Epub ahead of print]
Ewertz M, Gray KP, Regan MM, Ejlertsen B, Price KN, Thürlimann B, Bonnefoi H, Forbes JF, Paridaens RJ, Rabaglio M, Gelber RD, Colleoni M, Láng I, Smith IE, Coates AS, Goldhirsch A, Mouridsen HT. Obesity and risk of recurrence or death after adjuvant endocrine therapy with letrozole or tamoxifen in the Breast International Group 1-98 Trial. J Clin Oncol. 2012 Oct 8. [Epub ahead of print].