Supplemental Table 1.Medium-term variability for CRP and IL-6 measurements in subgroups.

Characteristics / n of patients / Log (CRP) / Log (IL-6)
VC
within subjects
+analytical / p value / VC
within subjects
+analytical / p value
Sex
Men
Women / 164
36 / 0.39
0.29 / 0.013 / 0.12
0.06 / < 0.001
Age
< 60 years
60-69 years
≥ 70 years / 81
71
48 / 0.34
0.34
0.48 / 0.003 / 0.13
0.11
0.09 / 0.016
Myocardial infarction
First MI
Re-MI / 175
25 / 0.37
0.36 / 0.834 / 0.11
0.09 / 0.120
BMI*
< 30 kg/m2
≥ 30 kg/m2 / 128
71 / 0.43
0.28 / < 0.001 / 0.12
0.10 / 0.037
Physical activity
Low or moderate
High / 140
60 / 0.37
0.38 / 0.818 / 0.11
0.10 / 0.454
Smoking status
Never smoker
Ex- or occasional smoker / 62
138 / 0.39
0.37 / 0.614 / 0.11
0.11 / 0.836
Alcohol intake*
None
Moderate
High / 29
134
35 / 0.40
0.34
0.49 / 0.004 / 0.09
0.11
0.12 / 0.226
History of diabetes
No
Yes / 165
35 / 0.37
0.40 / 0.563 / 0.11
0.10 / 0.408
History of hypertension
No
Yes / 98
102 / 0.36
0.39 / 0.483 / 0.11
0.11 / 0.660
Statin intake
No
Yes / 27
173 / 0.44
0.36 / 0.137 / 0.14
0.11 / 0.021
Total cholesterol
< 250 mg/dL
≥ 250 mg/dL / 188
12 / 0.38
0.27 / 0.122 / 0.11
0.10 / 0.531
HDL cholesterol
< 35 mg/dL
≥ 35 mg/dL / 19
181 / 0.37
0.37 / 0.893 / 0.14
0.11 / 0.141

Significant differences in within+analytical VC are marked bold (p< 0.05)

* missing values (BMI: n =1, Alcohol intake: n = 2)

CRP = C-reactive protein; IL-6 = Interleukin-6; MI = Myocardial infarction; BMI = Body mass index; VC = Variance component;HDL: High density lipoprotein

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