Katherine R. Henry

Maiden name, Katherine R. Heberlein

E-mail:

Appointments

• Academic Advisor, Public Health Studies, Johns Hopkins University,

8/2016-Current.

• Adjunct Faculty, General Biology for Non Majors, Biology, Towson University,

1/2015-5/2016.

• Postdoctoral Fellow, Lung Physiology. Pediatric Pulmonology, Johns Hopkins University,

8/2012-7/2016. Pamela Zeitlin, M.D., PhD

• Postdoctoral Fellow, Vascular Physiology. Anesthesiology and Critical Care Medicine, Johns Hopkins University, 8/2011-7/2012. Nicholas Flavahan, PhD

• Graduate Student. Molecular Physiology. Molecular Physiology and Biological Physics, University of Virginia, 09/2007-7/2011. Brant E. Isakson, PhD

o Visiting Graduate Student (9-10/2009): Medical University of Vienna, Vienna Austria; Johann Wojtia, PhD

Education

• Teaching Pedagogy Seminar, Towson University, 09/2014-12/2014.

• PhD., Molecular Physiology and Biological Physics, University of Virginia,

09/2007-7/2011.

• B.S., Biotechnology, Elizabethtown College, 09/2003-05/2007.

Organizations

• National Academic Advising Association, 2016-present

• American Physiological Society, 2008-present

• Microcirculation Society, 2008-2011

Articles

• Henry, K.R.., Lee, S., Walker D., Zeitlin, P.L. Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells. Physiol Rep, 2015. Jan 27;3(1). pii: e12264. doi: 10.14814/phy2.12264. Print 2015 Jan 1. PMID: 25626868.

• Kavoussi, PK., Heberlein K., Straub, A.C., Lowe, G.J., Oliver, J.L., Smith, R.P., Steers, W.D., Annex, B.H., Isakson, B.E., Lysiak, J.J.. Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice. Andrologia, 2014. Dec;29 doi: 10.1111/and.12395. [Epub ahead of print]. PMID: 25557984.

• Lee, S., Henderson M.J., Schiffhauer E., Despani J., Henry, K., Kang, P.W., Walker D., McClure, M.L., Wilson L., Sorscher, E.J., Zeitlin, P.L. Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools. Mol Cell Bio, 2014. Jul;34(14):2554-65. PMID: 24777605. PMCID: 4097669.

• Heberlein K.R., A.C. Straub, A.K. Best, J. Wojta, B.E. Isakson. Identification of a novel RNA binding protein complex to promote localized increases in plasminogen activator inhibitor-1 at the myoendothelial junction. Arterioslcer Thromb Vasc Biol, 2012. May;32(5):1271-9.

• Billaud M, Ross JA, Greyson MA, Bruce AC, Seaman SA, Heberlein KR, Han J, Best AK, Peirce SM, Isakson BE. A new method for in vivo visualization of vessel remodeling using a near-infrared dye. Microcirculation. 2011 Apr;18(3):163-71.

• Heberlein K.R., A.C. Straub, A.K. Best, M.A. Greyson, R. Looft-Wilson, P.R. Sharma, A. Meher, N. Leitinger and B.E.Isakson. Plasminogen activator inhibitor-1 regulates myoendothelial junction formation. Circulation Research, 2010 Apr;18(3):163-71

o Segal, SS., Bagher P. Regulation of myoendothelial junction formation: bridging the gap. Circ Res, 2010 Apr 2;106(6): 1014-6.

• Straub A.C., M.J. Rizzo, S.R. Johnstone, K.R. Heberlein, A.K. Best, S. Boitano and B.E. Isakson. Connexin phosphorylation can regulate heterocellular communication between smooth muscle and endothelium. J. Vasc Res, 2009 Dec;47(4):277-286

• Heberlein K.R., A.C. Straub, and B.E. Isakson. The myoendothelial junction: breaking through the matrix? Microcirculation, 2009 May;16(4):307-22

Funding

• Principal Investigator 07/01/2010-06/30/2012. American Heart Association MAA Predoctoral Fellowship. “Localization and function of plasminogen activator inhibitor-1 mRNA binding proteins to the myoendothelial junction”.

Academic and Professional Awards

• Meritorious Research Travel Award, Epithelial Transport Group of the American Physiological

Society, 2016

• T32 Pediatric Pulmonology Fellowship Program, Johns Hopkins, 2013-current

• Zweifach Graduate Travel Award, Microcirculatory Society, 2010

• Robert M. Berne Outstanding Trainee Award, University of Virginia School of Medicine, 2009

• Cardiovascular Research Training Grant, University of Virginia School of Medicine, 2009-2010

Abstracts

• Henry K.R., S. Lee, P.L. Zeitlin, Regulation of Cell Junctions by ClCN2 in Cystic Fibrosis. FASEB: 2016.

• Henry K.R., S. Lee, P.L. Zeitlin, Regulation of Ion Channels in Cystic Fibrosis. NACFC: 2014.

• Henry K.R., E. Schiffhauer, P.L. Zeitlin, Regulation of Ion Channels in Cystic Fibrosis. FASEB: 2014.

• Henry K.R., E. Schiffhauer, P.L. Zeitlin, Regulation of Ion Channels by Prostone Treatment for Cystic Fibrosis. NACFC: 2013.

• Henry K.R., E. Schiffhauer, P.L. Zeitlin, Modulation Of Airway Epithelial Apical And Basolateral Membrane Ion Channels By Prostones. ATS: 2013.

• Heberlein K.R.., A.C. Straub, A.K. Best, J. Wojta and B.E. Isakson. Nicotinamide phosphoribosyl transferase coordinates stabilization of plasminogen activator inhibitor-1 mRNA at the myoendothelial junction. FASEB: 2011.

• Heberlein K.R. A.C. Straub, A.K. Best, M.A. Greyson, R. Looft-Wilson, P.R. Sharma, A. Meher, N. Leitinger and B.E.Isakson. The potential for localized translation and induction of plasminogen activator inhibitor-1 at the myoendothelial junction in response to TNF-alpha. FASEB: 2010. [selected for oral and poster presentation]

• Rizzo M.J., S.R. Johnstone, A.C. Straub, K.R. Heberlein, A.K. Best, S. Boitano and B.E. Isakson. Connexin phosphorylation can regulate heterocellular communication between smooth muscle and endothelium. International Gap Junction Conference, 2009.

• Heberlein K.R. and B.E. Isakson. Proteomic analysis of the myoendothelial junction. FASEB: 2009.

• Heberlein K.R and B.E. Isakson. Plasminogen activator inhibitor-1 can regulate myoendothelial junction formation. FASEB: 2009.

• Heberlein K and B.E. Isakson. 2D-DIGE analysis of myoendothelial junctions. Keystone Conference: Dissecting the Vasculature: Function, Molecular Mechanisms and Malfunction; Vancouver, 2009