HUMAN PHYSIOLOGY – HS2410SPRING 2016

The Faculty, Fellows, Students, and Staff of the Physiology Department welcome you to the Human Physiology HLSC2410 course. Physiologistsexplore the normal functioning of living organisms. In Human Physiology, functional processes within each organ system of our bodies are studied todetermine how homeostasis, the maintenance of an optimal internal environment that supports cellular life, is achieved. These processes, resulting from regulated functions of each organ system, involve coordinated neural and hormonal communicationsystems. We will study each system individually, and as the course progresses, you will learn to integrate each system to understand how homeostatic regulation of the whole body attempts to return abnormal function to normal homeostasis. Our goal is to help you achieve a working knowledge of physiology,not just a memory bank full of physiological facts, as you acquire an understanding of and an appreciation of organ function and homeostatic control mechanisms. E.H. Starling, afamous physiologist of the early 20thcentury, once remarked that "The physiology of today is the medicine of tomorrow." We hope your efforts to learn physiology will equal or surpass our efforts to teach you this most important science for all healthcare professionals.

I. COURSE CO-DIRECTORS: Dr. Raymond E. Shepherd and Dr. Lisa M. Harrison-Bernard

The Course Co-Directorsare directly responsible for supervision and administration of HS2410. Any policy or schedule change will be formally announced by Dr. Shepherdand/or Dr. Harrison-Bernard by E-mail or Moodle.Dr. Harrison-Bernard is pleased to schedule an appointment by E-mail to meet with you in her office. She is unable to meet with students that do not have a prior appointment.Dr. Shepherd has an open door policy – if the door is open, come in. However, prior appointments will reserve your requested date and time with Dr. Shepherd.

II. INSTRUCTORSBuilding/Rm Office PhoneE-mail address

Raymond E. Shepherd, PhD MEB,

Lisa M. Harrison-Bernard, PhDMEB,

Anthony A. Duplanty, PhDMEB,

Jason D. Gardner, PhDMEB,

Alan J. Mouton, BS; PhD StudentMEB,

Andrew A. Pellett, PhDN/AH,

Andrew L.Pitt, CRNA, DNPN/AH,

Annie M. Whitaker, PhDMEB,

Barry J. Potter, PhDMEB, 7C10

Flavia M. Souza-Smith, PhDMEB,

John B. Zamjahn, PhDN/AH,

Margaret A. Zimmerman, PhDTulane Med

Stefany D. Primeaux, PhDMEB,

III. LEARNING PHYSIOLOGY

Doing well in Physiology will require concentrated effort on your part, as you will become involved in your own learning process.The following tips will enhance your chances for success in this course:

  1. A cursory understanding of the material is only the foundation from which to begin studying. Use the questions in the textbook to help guide your understanding of the physiologic concepts presented in class.
  2. Facts are only memorized; understanding physiology requires integration and application of concepts. Ask yourself, “What is the primary concept this unit covers?” Then study to understand the application of that concept to physiologic regulation of whole-body homeostasis.
  3. One learns by hearing what is being taught, observing what is being taught, experiencing what is being taught, and then teaching another person what was taught to you. Use this process during your learning.
  4. Read carefully the assigned and relevant chapters and sections in the textbookbefore class sessions.
  5. Take your own notes during lectures. As soon after the lecture as possible, integrate your notes with the textbook (focus ontables and figures) and other lecture materials. Look at the material from different angles. Embrace this new experience of learning.
  6. Form small study groups and meet at least once per week throughout the entire semester. Review class material by taking turns “teaching” theother members of thestudy group. You will really understand physiology when you can help another student learn physiology.
  7. Apply facts and concepts presented in the lecture to the clinical scenarios presented in the textbook. Moderate to severe exercise is used as a clinical scenario throughout the course because we can easily visualize thisactivity.

IV. LECTURES, ATTENDANCE, TEXTBOOK

Lectures: Class meets Tues and Fri from8-10AM (LH-C) in the Nursing-Allied Health Bldg. Class begins at 8 AM sharp.The lectures support and supplement the textbook. The textbook will help you understand basic physiological concepts as applied to patient care. Read the assigned chapter in the textbook prior to class. You mustachieve a working knowledge of physiology, not just memorizing physiological facts. Our emphasis will be on the application of physiological concepts for patient care.

Textbook: Human Physiology: The Mechanisms of Body Function by Widmaier, Raff, and Strang, 13th edition (McGraw-Hill: ISBN9780073378305). Earlier versions of the textbook are not recommended. Our PPT slides are notequal to the textbook. You are responsible for applying the textbook material to supplementthePPT slides thatwe present in class. Read and study the textbook as you study the slides.

Laboratory: The ECG lab (MEB-MDL #6) will be given on Tues andThurs from 1-4 PM. You needattend only one session of this lab(AbPsych students must have lab on Tues). The MDL labs are on the 4th floor of the Medical Education Building (MEB). Clinical correlation labs will bein LH-Cfrom 1-3PM on Tuesdays for all students.ADOBE presentations are optional and will be posted to the Moodle website for you to listen wherever and whenever you prefer. The ADOBE presentations are includedto enhance your understanding of the material being presented in class.

Cell Phones: Cell phones are to be on vibrate during class and kept out of sight. If an emergency exists, take the call outside of the classroom. Please, respect our learning environment.

Electronics: Tablets, iPad, notebooks,and small computersmaybe used in the classroom for the sole purpose of viewing the lecture material and taking notes.Your face is better to communicate with than a computer lid. You may record,but not videotape the lecture.Do not take snapshots with any electronic devices.

Tutoring: Tutoring for the courseis provided by our advanced physiology PhD students. Alan Mouton is the assigned tutor for the course and will conduct weekly question and answer review sessions. You may contact John Maxi and Jacques Mayeux for private tutoring.

Students with Disabilities: Students who have authenticated disabilities must petition the Nursing School Administrative Assistant Dean, Ms. Kendra Barrier. Ms. Barrier will inform the course director that you will receive additional time and/or special accommodations for exams or other course functions.

Academic Honesty: Use of any unauthorized material or method other than your knowledge and memory to answer questions on an exam constitutes cheating and will result in yourfailing that exam and possibly failure of the course. The Dean of the School of Nursing will be notified.

Clickersign-up: Purchase you Turning Technologies Clicker Device from the bookstore. Included in the box with the clicker device is a card with a number on it that you will need to register for the class at Turning Technologies.

V. EXAMINATIONS AND GRADING

Exam Schedule:Four unit exams will be given during the course; Exam 5is a Comprehensive Final.Unit exams are Tuesdays 8AM-10AM. BSN students will report to the Computer Testing Lab, 5th Floor, N/AH. CARE students willreport at the same time to LH-A N/AH building, with laptop computer, Respondus lockdown browser software, power cord, and an internet cable.You will have 2 hours to complete the exam once the exam starts.Students with documented disabilities will test in the ADA room. ADA students will be given 3 hr to complete the exam once started. There will be no extension of time.

Attire and Personal Material: Caps and other headgear, and water and food are not allowed during the exam. We will supply paper upon which you can write or calculate as you answer the exam questions. You provide a pen or pencil. Signyour papers before leaving the NSTC or LH-Atest site so when you come to review the concepts of the exam with us, we will be able to find your paper.Moodle provides calculators, if needed.Leave cell phones turned off in your book bag.If you expect an emergency call during the exam, silence your cell phone, leave it with the proctor so we can notify you should you receive a call. All material must be stored in the designated storage areas in the NSTC.CARE students will place all personal materialsin the front of LH-Abefore being seated in every third seat of alternate rowsfor the exam period.

Exam Format:All examinations will consist of 50 multiple-choice questions that are submitted to the co-directors for final review. Each exam question will have 4 possible choices that utilize clinical scenarios that will test your understanding(know and apply facts) of physiologic principles that have been covered in lecture, lab, and in the textbook.Exams will start promptly at 8AM. Be seated quickly, activate Respondus, and log into Moodle.The password to activate the exam will be posted at the door (NSTC) or on the front screen (LH-A). Exams are limited to exactly 2 hours. If you arrive 1 hour after the exam starts, you will have missed the exam, and will have to make arrangements to take a make-up exam with documentation from Ms. Barrier.

Missing an Exam:Students must submit hand-written documentation from Ms. Barrier to the course director for missing an examination period. Please inform the Course Director before the exam if you will be absent. If a student misses an exam because of an emergency, informs the course director within 24 hours after the exam has been given, and has the necessary documentation for their absence, the student will be offered a make-up exam. Make-up exams may be multiple choice, but likely willbe oral and essay format. Students with a valid excuse must take a “make-up” exam within one week of returning to school. It is the student’s responsibility to schedule this make-up exam. Failure to take the exam or the make-up exam results in a “0” for that exam. This grade cannot be replaced with the final exam grade.This does not apply to clicker quizzes. There are no make-up clicker quizzes given for any student for any reason. Students who submit documentation from Ms. Barrier to a Course Director for missing a clicker quiz will receive the attendance credit only for the missed quiz.

Exam Reviews: Exams are evaluative and not instructional. We will notreview the exam key with you. We willdiscuss physiological concepts related to the notes you wrote on your scratch paper during the exam.

Clicker Quizzes:Make certain your clicker is in working order and carry extra batteries.Connection with the class computer is indicated when the projected clicker number darkenson the overhead screen.Clickers may take up to 5 sec to connect.Submit your clicker answer at least5 sec prior to the end of the question timer.Check with einstruction.com afterevery clicker quiz to make sure your clickers made contact with their site. Check with us if Turning Point did not record your score. Notify usthat dayif contact was not made.No notification=No Credit.If your clicker is not working, you may take the quiz by paper and penonly if you are seated in the front of the classroom during the entire quiz. One point will be earned for attendance and one point will be earned for answeringeach clickerquestion correctly. All clicker points are added together and constitute Exam#6 for the semester. The percentage clicker quiz score is determined by dividing [[number correct]/[total]] X 100. If we have 100 clicker quizzes during the semester, and you score 180 of the 200 total points, you have 180/200 or a score of 90% for Exam #6.

VI. STUDENT EVALUATION

Exams are graded as %Score: [Correct/Total X 100].Each exam question is analyzed by a statistical program,and both Drs. Harrison-Bernard and Shepherd scrutinize each answer before we release the gradeson Moodle. We recognize you may have a ‘bad hair day’ and do poorly on oneunit exam. If your Final Comprehensive Exam #5 score is higherthan any one score on unit Exams 1-4, then the final exam score will substitute for that lowest score, as well as, be counted for the Exam #5 score. The Exam #6 for clicker quizzeswill NOT be included for this grade substitution. Final grades are based on your TOTAL score (600 pts) from the five exams (500 pts) plus the clicker quizzes (100 pts). The grading scale is 90%-80%-70%-60% for A-B-C-D, respectively. Scores are absolute. A final score of 539 is a “B” and a score of 540 is an “A.”We do not“curve” the exams or the grades. The Course Final Gradesare determined by summing the %correct for each exam. The total summed score is the Total Points earned during the semester.

ExamPtsFinalPercentageTotal Points

Exam I100A90 – 100540 - 600

Exam II100B80 – 89480 - 539

Exam III100C70 – 79420 - 479

Exam IV 100D60 – 69360 - 419

Exam V-Final100F 59000 -359

Exam VI (Clickers)100

Total Points600

Spring 2016Classes begin Wed 13Jan16

Mardi Gras Tues 9Feb16

Spring break Tues 22Mar16 – Tues 29Mar16

Reading day Fri 6May16

Final Exams Mon 9May16 – Thur 12May16

Last day of semester 13May16

Pre-commencement Wed 18May16

Graduation Thur 19May16

VIII. COURSE SCHEDULE

No.Day/DateTIME and TOPICInstructor______

01F 15 Jan8Homeostasis: Maintenance of Internal Environment (Ch 1)Dr. Shepherd

02F 15 Aug9Cell Physiology: Cell Function – Metabolism (Ch 3)Dr. Shepherd

03T 19 Jan8Cell Physiology: Membranes – Molecular Structure (Ch 3)Dr. Primeaux

04T 19 Jan9Cell Physiology: Diffusion, Osmosis (Ch 4)Dr. Primeaux

LABT 19 Jan1How To StudyDr. Harrison-Bernard

05F 22 Jan8Cell Physiology: Membrane Transport (Ch 4)Dr. Primeaux

06F 22 Jan9BioCommunication: Electrical Properties of Membranes (Ch 4)Dr. Primeaux

07T 26 Jan8BioCommunication: Action and Graded Potentials (Ch 6)Dr. Primeaux

08T 26 Jan9BioCommunication: Synapses and Signaling (Ch 6)Dr. Primeaux

LAB #1T 26 Jan1 PM Fluids, Electrolytes, and ResuscitationDr. Shepherd

09F 29 Jan8BioCommunication:Neurotransmitters & Receptors (Ch 5)Dr. Primeaux

10F 29 Jan9BioCommunication: Sensory Physiology (Ch 7)Dr. Primeaux

11T 02 Feb8BioCommunication: Body Movement and Reflexes (Ch 10)Dr. Duplanty

12T 02 Feb9BioCommunication: Skeletal Muscle (Ch 9-A)Dr. Duplanty

Exam #1: 8-10 AM, Fri, 05 Feb 2016, Lectures 1-12, Lab #1 (NCTS, N/AH 5th Floor; LH-A)

T 09 FebMARDI GRAS

13F 12 Feb8BioCommunication: Cardiac and Smooth Muscle (Ch 9-B)Mr. Mouton

14F 12 Feb9BioCommunication: Autonomic Nervous System (Ch 6-18)Mr. Mouton

15T 16 Feb8Endo: Hypothalamus and Pituitary Gland (Ch 11-B)Dr. Shepherd

16T 16 Feb9Endo: Thyroid-Parathyroid Gland (Ch 11-C)Dr. Shepherd

17F 19 Feb8Endo: Adrenal Gland (Ch 11-D)Dr. Shepherd

18F 19 Feb9Endo: Pancreas (Ch 16-2)Dr. Shepherd

19T 23 Feb8Endo: Growth Hormone (Ch 11-E)Dr. Shepherd

20T 23 Feb9Endo: Physiology of Reproduction (Ch 17)Dr. Shepherd

21F 26 Feb8CV: Blood and Blood Components (Ch 12-F)Dr. Potter

22F 26 Feb9CV: Hemostasis, INR (Ch 12-F)Dr. Potter

23T 01 Mar8CV: Innate Immune Responses (Ch 18-1, 2)Dr. Potter

24T 01 Mar9CV: Acquired Immune Responses (Ch18-3)Dr. Potter

25F 04 Mar8CV: Overall Design and Hemodynamics (Ch 12-A)Dr. Harrison-Bernard

26F 04 Mar9CV: Electrical Activity of the Heart (Ch 12-B)Dr. Harrison-Bernard

Exam #2: 8-10 AM, Tues, 08 Mar 2016, Lectures 13-24 (NCTS, N/AH 5th Floor; LH-A)

27F 11 Mar8CV: Heart as a Pump (Ch 12-B)Dr. Gardner

28F 11 Mar9CV: Cardiac Cycle/Cardiac Output (Ch 12-B)Dr. Gardner

29T 15 Mar8CV: Vasculature and Microcirculation (Ch 12-C)Dr. Souza-Smith

30T 15 Mar9CV: Venous Return (Ch 12-C)Dr. Souza-Smith

LAB #2 T 15 Mar1 PM ECG Lab (MDL #6)Dr. Gardner

LAB #2 Th 17 Mar1 PM ECG Lab (MDL #6)Dr. Gardner

31F 18 Mar8CV: Regulation of Mean Arterial Blood Pressure (Ch 12-D)Dr. Whitaker

32F 18 Mar9CV: Review of Cardiovascular Physiology (Ch 12-E)Dr. Whitaker

No.Day/DateTIME and TOPICInstructor__

T 22 MarNO CLASS

SPRING BREAK 22Mar16 5PM to 29Mar16 7AM

33T 29 Mar8Respiratory: Organization (Ch 13-1, 2)Dr. Pellett

34T 29 Mar9Respiration: Exchange of Gases (Ch 13-3)Dr. Pellett

35F 01 Apr8Respiration: Ventilation and Perfusion (Ch 13-3)Dr. Pellett

36F 01 Apr9Respiration: Transport of Gases (Ch 13-4, 5, 6)Dr. Pellett

37T 05 Apr8Respiration: Control of Breathing (Ch 13-7, 8, 9)Dr. Pellett

38T 05 Apr9GI Function, Motility, and ENS (Ch15)Dr. Shepherd

LAB #3T 05Apr1 PM Pulmonary Function Tests (LH-C)Dr. Zamjahn

39F 08 Apr8GI: CephalicPhase of Digestion (Ch 15)Dr. Shepherd

40F 08 Apr9GI: Gastric Phase of Digestion (Ch 15)Dr. Shepherd

Exam #3: 8-10 AM, Tues, 12Apr 2016, Lectures 25-37, Lab #2 (NCTS, N/AH 5th Floor; LH-A)

41F 15 Apr8GI:Intestinal Phase of Digestion (Ch 15)Dr.Shepherd

42F 15 Apr9GI: Metabolism and Energy Balance (Ch 16)Dr. Shepherd

43T 19 Apr8Renal: Structure, Basic Processes(Ch 14-A)Dr. Harrison-Bernard

44T 19 Apr9Renal: Epithelial Transport Mechanisms (Ch 14-A)Dr. Harrison-Bernard

LAB#4T 19 Apr1CV, Renal: Hypertension and the Kidney (LH-C)Dr. Zimmerman

45F 22 Apr8Renal: GFR, Clearance, Intra-renal homeostasis (Ch 14)Dr. Harrison-Bernard

46F 22 Apr9Renal: Sodium and Potassium Balance (Ch 14-B)Dr. Harrison-Bernard

47T 26 Apr8Renal: Water Balance (Ch 14-B)Dr. Harrison-Bernard

48T 26 Apr9Renal: Hydrogen Ion and Acid-Base Balance(Ch 14-C)Dr. Harrison-Bernard

LAB#5T 26 Apr1 PM Arterial Blood Gases from a Clinical SettingDr. Pitt

Exam #4: 8-10 AM, Tues, 03 May 2016 Lectures 38-48, Labs #3-4 (NCTS, N/AH 5th Floor; LH-A)

FINAL EXAM #5: Time-TBA Tue, 10 May 2016

Lectures 1-48, Labs #1-4 (NCTS and LH-A)

Each student is required to complete the Moodle Syllabus Quiz prior to Friday, January 15, 2016 to attest to your reading and understanding the content of the class schedule.

AGAIN – Your respectful and professional comments for this Course Evaluation will be used to maintain the strengths of the course and implement your suggestions on how the course can be improved. The purpose of this evaluation is to assist your professors in providing the best possible education to you on the functioning of the human body as related to healthcare professionals. Although, your comments are being made in anonymity, they will be read by the course directors, program directors, and deans of your school.

Mon / Tuesday / Wed / Thu / Friday
Jan / 11 / 12 / 13
ClassBegins / 14 / 15
L01 Homeostasis
L02 Cell Function - Metabolism
18
MLK Day / 19
L03 Cell Function – Membranes
L04 Diffusion – Osmosis
LAB: How To Study / 20 / 21 / 22
L05 MembraneTransport
L06 Electrical Properties of Membranes
25 / 26
L07 Action and Graded Potentials
L08 Synapses and Signaling
Lab 1: Fluids, Electrolytes, Resuscitation, LH-C / 27 / 28 / 29
L09 Neurotransmitters and Receptors
L10 Sensory Physiology
Feb / 01 / 02
L11 Neural Pathways and Body Movement
L12 Skeletal Muscle / 03 / 04 / 05
8-10 AM: Exam #1 L01-L12; Lab #1
08 / 09
MARDI GRAS / 10 / 12 / 13
L13 Cardiac-Smooth Muscle
L14 Autonomic Nervous System
15 / 16
L15 Endo: Hypothalamus and Pituitary
L16 Endo: Thyroid-Parathyroid / 17 / 18 / 19
L17 Endo: Adrenal Gland
L18 Endo: Pancreas and Metabolism
22 / 23
L19 Endo: Growth Hormone
L20 Endo: Physiology of Reproduction / 24 / 25 / 26
L21Hematopoiesis
L22 Hemostasis
Mar / 29 / 01
L23 Innate Immunity
L24 Adapted Immunity / 02 / 03 / 04
L25 CV: Overall Design/Hemodynamics
L26 CV: ECG and Electrical Activity
07 / 08
8-10 AM: Exam #2 L13-L24 / 09 / 10 / 11
L27 CV: Heart as a Pump
L28 CV: Cardiac Cycle/Cardiac Output
14 / 15
L29 CV: Vasculature and Microcirculation
L30 CV: Venous Return
Lab #2: ECG, MDL 6 / 16 / 17
ECG Lab,
MDL 6 / 18
L31 CV: Regulation of MABP
L32 CV: Review of Cardiovascular Physiology
21 / 22
NO CLASS / 23 / 24 / 25
GOOD FRIDAY
28 / 29
L33 Respiratory: Mechanisms of Breathing
L34 Respiratory: Lung Volumes; Gas Exchange / 30 / 31 / 01
L35 Respiratory: Ventilation/Perfusion
L36 Respiratory: Gas Transport
Apr / 04 / 05
L37 Respiratory: Control of Breathing
L38 GI: Function, Motility and ENS
Lab #3: PFT, LH-C / 06 / 07 / 08
L39 GI: Cephalic phase of Digestion
L40 GI: Gastric Phase of Digestion
11 / 12
8-10 AM: Exam #3 L25-37, Lab #2-3 / 13 / 14 / 15
L41 GI: Intestinal Phase of Digestion
L42 GI: Metabolism and Energy Balance
18 / 19
L43 Renal: Structure and Basic Processes
L44 Renal: GFR, Clearance, Transport
Lab #4: Hypertension and the Kidney / 20 / 21 / 22
L45 Renal: Epithelial Transport
L46 Renal: Sodium and Potassium Balance
25 / 26
L47 Renal: Water Balance
L48 Renal: H+ ion Regulation & Renal Diseases
Lab #5: ABGs, LH-C / 27 / 28 / 29
NO CLASS
02 / 03
8-10 AM: Exam #4 L38-L48, Lab #4-5 / 04 / 05 / 06
Reading Day
May / 09
Exams / 10
Comprehensive Final Exam #5:
L01-L48, Lab #1-5 / 11
Exams / 12
Exams / 13
Final Day of Semester

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