Grade Level/Subject / High School / Biology
Unit / Cell Structure and Function – Cell Size
Enduring Understanding /
  • As cells increase in size, surface area to volume ratios decrease, making cells unable to obtain nutrients or remove wastes. To reduce the effects of this, cells divide to stay small or change shape to increase surface area or reduce volume.

SOL Objectives / BIO.3The student will investigate and understand relationships between cell structure and function. Key concepts include
a)evidence supporting the cell theory;
b)characteristics of prokaryotic and eukaryotic cells;
c)similarities between the activities of the organelles in a single cell and a whole organism;
d)the cell membrane model; and
e)the impact of surface area to volume ratio on cell division, material transport, and other life processes.
BIO.1The student will demonstrate an understanding of scientific reasoning, logic, and the nature of science by planning and conducting investigations.
Title / Why are cells so small?
Lesson Objective / Students will explore how surface area to volume ratios effect the functioning of cells They will design an experiment that mimics this through studying how heat transfer varies in different sized potatoes. They will find that smaller potatoes (cells) are more efficient in carrying out cellular process, such as heat transfer, osmosis, and waste elimination.
Inquiry Level / Level 3 – Students will be given the question to answer and materials, but will need to come up with their own methods.
Materials Required / Sugar cubes, oven or toaster oven, potatoes of varying sizes, rulers, calculators, probeware thermometers (optional)


Name______Period:______

Why are cells so small?

Today'slabisaboutthesizeofcells.Tounderstandthis,wefirsthavetounderstandsurfaceareato

volumeratios.

Let'sstartwithsurfacearea.Getaboxofsugarcubes.Thesurfaceareaofthecubeiscalculatedby

findingthearea(lengthxwidth)ofoneside.Butwewanttoknowthewholesurface.Onacube,there

are6sides,sowemultiplythatareax6.So

Surfaceareaofacube=lengthxwidthx6

Volumeisanothersimplecalculation-wejustmultiplylengthxwidthxheight.Buildthefollowingfour

structuresfromyoursugarcubes,andfilloutthetablebelow.

ABC D

1UNIT2UNITS 3 4UNITS

ORCM UNITS

FigureTotalnumberSurfaceareaof Volumeof Surfaceareato Totalsurface

A

B

C

D

ofCubes

figure

(=6xlengthx

width)

figure

(=lengthx

widthxheight)

VolumeRatio

SA/V

ofindividual

cubes

SurfaceAreatoVolumeLabQuestions

1.Whathappenedtothesurfaceareaasthesizeincreased?

2.Whathappenedtothevolumeasthesizeincreased?

3.Whathappenedtothesurfaceareatovolumeratioasthesizeincreased?

4.Nowimagineyou'relookingataverylargecell.Nexttoitisaverysmallcell.Whichonehasalarger

surfaceareatovolumeratio?

SurfaceAreatoVolumeLabPartII:HotPotato-Inquiry

Nowyouaregoingtoapplywhatyoujustlearnedaboutsurfaceareatovolumeratios.Yourjob

istofigureouthowthiswholethingappliestobiology.

Thecellsyou'velookedatinbiologyhaveallbeenwiththeuseofamicroscope:they'veallbeenvery,verysmall.Butsomecellsarenot-theyaremuchbigger,andyoucanevenseethemwithoutanyhelpfrommagnifyingglassesoranything‐forexample,a

chickenegg.That'sallonecell!Whatisthelargestcell?It'sdisputed,butsomesayitis

theostrichegg.Othergigantoidcellsincludethenervecellofthegiantsquid(overameterlong!)and

somealgaewhichhavelargecells.Butmostcellsaretiny.

Why?

You'velearnedaboutosmosisanddiffusion.Thisishowcellsgetalmosteverythingtheyneed:

nutrients,ions,water,etc,andhowtheygetridofwastes.Willdiffusionandosmosisbeenoughto

supportjustanycell?

Questions

1.Doyouthinklargecellsandsmallcellscarryoutdiffusionandosmosisatthesamerate?Whyorwhy

not?

2.Ifacellhasahighconcentrationofsomething,say,waste,thatitwantstogetridof,whichdoyou

predictwillbeabletogetridofthewastesooner-asmallercelloralargeone?

Now,designanexperimenttotestyourhypothesisfromquestion#2.

Wehavelargeandsmallpotatoestomodelcells.Theyarehot.Justlikeincellularprocesses,heat

diffusesoutofareasofhighconcentrationtoareasoflowconcentration,whichmakesitagreat

demonstrationfortestingquestionslikethis,sincecellsareveryhardtoworkwith.

Wewillapplythehypothesisfromquestiontwotothepotatoes.Ifyouhavealargehotpotatoanda smallhotpotato,andtwothermometers(andusinganythingelsearoundtheroomyoucanthinkofif

youwant),howcanyoutestyourhypothesisthatonepotato(whicheveryoupredictedabove)willlose

heatfasterthantheother?Whatwillyoumeasureandhowwillyoumeasureit?Describeyour

experimentbrieflybelow,using1‐2completesentences.

Onceyouhavecomeupwithanexperiment,bringyourpapertoyour teachertoapproveyourexperimentandtogetyourtwohotpotatoesandbegin.

Data

Graphyourdatabelow.Makesuretolabelyourxandyaxis.Useadifferentcolorlineforyour

differentpotatoes.

Questions

3.Whichpotatocooledofffaster? Why do you think?

4.Ifthepotatowasacell,andtheheatwaswastethecellwastryingtogetridof,whichcelldoyou

thinkwouldhaveanadvantage?

5.Howmightsurfaceareatovolumeratioshelpdecidethesizeofcells?

6.Basedonwhatyouhavelearnedtoday,inwhatwaymaymulticellularorganismshaveanadvantage

oversingle‐celledones?

7.Consideramouseandanelephant.Ifbothwereleftinthecoldovernight,whichwouldbeinmore

dangeroffreezingtodeath?Why?

8. How could this experiment be improved or expanded?