Translational Medicine轉譯醫學

Semester:Fall 2013

Program: Translational Medicine Degree Program

Place:TIGPBuilding, Auditorium 207

Time: Wednesday, 14:00~17:00 PM

Instructor:Dr.陳鈴津(Yu, AliceLin-Tsing)/Dr.杜邦憲(Tu, Pang-Hsien)

Credit:3

Scope of Translational Medicine includes:

1) understanding mechanisms of human disease and relevant research models;

2) learning the development process of new drugs or technologies (biomarkers, medical device) for diagnosis, prevention and therapeutic interventions;

3) learning bioethical issues and regulatory guidelines relevant to human research

Syllabus of Translational Medicine:

17 sessions of 3 hour class +term paper (******Note: Study must contain aim(s) to collect human samples with application for IRB approval*****)

Method: Lecture, discussion

Evaluation: Report(Plagiarismis not allowed.)

Textbook: Handout in class *Thiscourseis taught in English.*

Week / Date / Time / Topics / Speaker
1 / 9/11 / 14:00~15:20 / Significance, Definition & Scope of Translational / 陳鈴津
15:30~16:50 / Medicine-Lab Bench to bedside & Bedside to Lab Bench / 張子文
2 / 9/18 / 14:00~15:20 / #1 IP protection, Management of Intellectual Property and Litigation / 劉孔中
15:30~16:50 / #2 Technology Transfer/ Incubation Center / 梁啟銘
3 / 9/25 / 14:00~14:50 / Clinical candidate selection/ leadoptimization/SAR & medical device
#1 Discovery and lead optimization of small molecule drugs / 陳孟炘
15:00~ 15:50 / #2Development of biologics / 阮大同
16:00~16:50 / #3 Development of new medical device / 蔡秀娟
4 / 10/2 / 14:00~15:20 / Stemcell/regenerative medicine/cell based therapy & Animal disease models
#1. Stem cell/regenerated medicine / 沈家寧
15:30~16:50 / Animal toxicology, safety pharmacology / 陳筱苓
5 / 10/9 / 14:00~15:20 / Stemcell/regenerative medicine/cell based therapy & Animal disease models
#2. Small animal disease models for preclinical studies / 陶秘華
15:30~16:50 / Success stories of drug development from the perspective of pharmacokinetics and ADME. / 謝興邦
6 / 10/16 / 14:00~15:20 / Stemcell/regenerative medicine/cell based therapy & Animal disease models
#3. Non-human primate for preclinical studies / 萬灼華
15:30~16:50 / Process scale-up and CGMP production of Small chemicals. / 程正禹
7 / 10/23 / 14:00~15:20 / VC and Financial Management in Biotech industry / 李世仁
15:30~16:50 / GMP, CMC, Scale up production, formulation
#3 Formulation / 顧曼芹
8 / 10/30 / 14:00~15:20 / #1 Clinical research design, monitoring system and data collection/analysis / 許 駿
15:30~16:50 / #2 Statistical considerations in clinical translationalresearch / 陳珍信
9 / 11/6 / 14:00~16:50 / Genomic medicine / 蔡世峰
10 / 11/13 / 14:00~15:20 / IND application & IRB issues
#1 Regulatory guidelines for investigationalagents/device / 陳恆德
15:30~16:50 / IND application & IRB issues
#2 IRB and conflict of interests / 郭英調
11 / 11/20 / 14:00~16:50 / Molecular Imaging in Translational Researches, Giving Models in Pre-clinical and Clinical Trials / 閻紫宸
12 / 11/27 / 14:00~16:50 / Mass spectrometry-based proteomic approaches for discovering and verifying body fluid-accessible cancer biomarkers / 陳怡婷
13 / 12/4 / 14:00~15:20 / #1 Viral Infection / 林宜玲
15:30~16:50 / #2 Vaccine development / 李敏西
14 / 12/11 / 14:00~16:50 / Translational research of Psychiatric disease / 陳嘉祥
15 / 12/18 / 14:00~16:50 / Targeted and individualized therapy of cancer / 楊泮池
16 / 12/25 / 14:00~15:20 / #1 Huntington's disease: clinical trials and drug development / 陳儀莊
15:30~16:50 / #2 Immunotherapy against neurodegenerative disease / 杜邦憲
17 / 1/1 / 元旦放假
18 / 1/8 / 14:00~15:20 / The translational research of galectins / 吳明恒
15:30~16:50 / What we learned from biomarker discovery to clinical application / 楊維中