Genetics Guided Notes

To be used with Genetics PowerPoint

History of Genetics:

Gregor Mendel:

  • Austrian monk lived from 1822-1884
  • Mendel developed principles of heredity

without any knowledge of genes or

chromosomes

  • His principles were established through

experiments with pea plants

Why was Mendel so successful with pea plants?

•Used pure breeding, contrasting traits

•Studied characteristics one at a time for many

generations

•Used mathematics in analyzing his results

•Obtained large numbers of offspring

•Chose pea plants which normally self-fertilize

•Used scientific method

•Inexpensive

Define genes: factors that control organism’s traits.

-the part of chromosome that contains the genetic code.

Every organism requires a set of coded instructions for specifying its traits

For offspring to resemble their parents, their must be a reliable way to transfer hereditary information from one generation to the next

Genetic Terms:

• ( ): the alleles on homologous chromosomes are the same

• : ( ): the alleles on homologous chromosomes are different

parental generation (P): the two original organisms being crossed - usually pure

first filial generation(F1):the first generation of offspring from the parents

second filial generation(F2):generation of offspring arising from the first filial generation

Genotype: the ______makeup of an organism

Homozygous Dominant: ____

Homozygous Recessive: ____

Heterozygous: ____

Phenotype: the ______of an organism

Describes what the organism looks like

TT - ______

tt - ______

Tt - ______

______:

a model used to predict the

results of a genetic cross

Three Laws by Mendel:

1. Law of Dominance: a pattern of heredity in which one allele of a gene may express

itself by masking the presence of the other allele

Define Dominant Trait:

Define Recessive Trait:

Example:

______x ______ ______

Example of Dominance:

R = red

r = white

Problem: Cross homozygous dominant with homozygous recessive

______x ______

What are the results?

Phenotype:

____ % red, ____ %white

Genotype:

____ % homozygous or heterzygous

2. Law of Segregation and Recombination Mendel’s Second Law:

When gametes are formed during meiosis three things happen. What are they?

When gametes are formed during meiosis:

There is a random segregation of homologous chromosomes

Random segregation of sister chromatids & alleles

The result: new gene combinations are likely to be produced

Segregation means separation and can lead to genetic recombination.

Example of Segregation:

Problem: Cross two offspring from the 1st filial generation (both are heterozygous)

______x ______

Results?

Phenotype:

_____% red, ____% white

Phenotypic ratio:

___ red : ___ white

Genotype:

___% homozygous dominant

___% homozygous recessive

___% heterozygous

3. Law of Independent Assortment Mendel’s Third Law

Scenario: Two different traits located on two different chromosomes

Explain what two things can happen to these traits during meiosis:

•They segregate randomly during meiosis

•May be inherited independently of each other

The cross of two organisms heterozygous for a trait is known as a dihybrid cross

Punnett Square Problem #3: Dihybrid Cross

T = tallt = short

Q = wrinkledq = smooth

Problem: Cross homozygous tall and homozygous wrinkled seeds with homozygous short and homozygous smooth seeds

Genotypes for this cross: TTQQ x ttqq

What are the phenotypes for these plants?

Punnett Square Problem #3: Dihybrid Cross

Genotypes for this cross: TtQq x TtQq

T = tallt = short

Q = wrinkledq = smooth

What are the phenotypes for these plants?

Incomplete Inheritance:

Two examples of Incomplete Inheritance:

Incomplete Dominance & Codominance

Define Incomplete Dominance:

Name one example of incomplete dominance
______

Define Codominance:

Name the first example of Codominance:

______

Example of Codominance:

Problem:
Cross offspring from 1st cross (2 heterozygous parents)

Problem 3: Cross two

heterozygous parents

R = red

r = white__ __ x __ __

Results:

Phenotype: ___% red, white___%

Phenotypic Ratio: __ : _ __

Genotype: ___% heterozygous

___% homozygous dominant

___% homozygous recessive

R = red __ __ x __ __

r = white

Results:

Phenotype: ___% red, white___%

Phenotypic Ratio: _____ : ______

Genotype: ___% heterozygous

___% homozygous dominant

___% homozygous recessive

Problem: Cross two heterozygous parents.

R = red __ __ x __ __

r = white

Results:

Phenotype:

___% red, ___& red and white, ___% white

Phenotypic Ratio:

__ ___ : ______: ______

Genotype: ___% heterozygous

___% homozygous dominant

___% homozygous recessive

Problem: Cross two heterozygous parents.

R = red __ __ x __ __

r = white

Results:

Phenotype:

___% red, ___& pink, ___% white

Genotype: ___% heterozygous

___% homozygous dominant

___% homozygous recessive

Traits that are controlled by more than 2 alleles

Results in multiple phenotypes

Examples:

Pigeons Blood groups in humans

BA dominant over B Four blood types A B AB & O

BA and B are dominant over

Polygenic Inheritance

A pattern of a trait that is controlled by 2 or more genes.

Phenotype express a range of variability.

Examples:Stem length, human height, eye color & skin color

Stem length for a totally recessive plant is____ cm.

aabbcc = 4 cmAABBcc = cm

Aabbcc = cmAABBCc = cm

AAbbcc = cmAABBCC = cm

AABbcc = cm

Gene Expression

Influence of External Environment:

Examples: Temp., nutrition, light, chemicals

Color of rabbit in the summertime: brown

Color of rabbit in the winter: white

The temperature effects what color fur (or what proteins) are expressed

Temp also determines the sex of a gator

Light determines color of bacteria

Influence of Internal Environment:

Examples: Hormonal influences

•Horn size in mountain sheep

•Male pattern baldness

•Peacock feathers

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