Figure S2. Heterozygous Deletion of Satb2 in Mice Leads to Impaired Social Memory

Figure S2. Heterozygous deletion of Satb2 in mice leads to impaired social memory

(A) Self-grooming time for Satb2+/+ mice (n = 17) and Satb2+/- mice (n = 15) was similar in 10 min. (B-F) 3-Chambered social test. Three divided chambers were named left, middle and right ones. During the first 10-min habituation phase, time spent in left and right chambers was close both in Satb2+/+ mice (n = 14) and Satb2+/- mice (n = 12) (B). During the second 10-min phase, time spent in left chamber with stranger 1 was higher than right chamber with an empty box both in Satb2+/+ mice and Satb2+/- mice (C) and the sniffing time spent on stranger 1 was also higher than that on the empty box (D). During the third 10-min phase, time spent in left chamber with stranger 1 and right chamber with stranger 2 were similar in Satb2+/- mice (E), and Satb2+/- mice also did not show an increase in the sniffing time spent on stranger 2 (F). Data shown are represented as mean ± SEM. * P 0.05. ** P 0.01. *** P 0.001.