FELLOWSHIP EXAMINATION JUNE/JULY 2001

VETERINARY DERMATOLOGY

PAPER 1

Perusal Time : 20 minutes

Time Allowed : FOUR (4) Hours after perusal

ANSWER FIVE (5) out of Six Questions Only

ALL QUESTIONS ARE OF EQUAL VALUE

Subsections of Questions are of equal value unless stated otherwise

  1. Canine hypothroidism has been described as the most common endocrinopathy.

a.Write an account of the physiological processes involved in the synthesis and secretion of thyroid hormone (20%).

b.Describe the mechanisms which may lead to measurable deficiency in thyroid hormone (30%).

c.List the clinical signs caused by thyroid hormone deficiency in the skin and write brief notes on their pathogenesis (50%).

  1. a. Describe the mechanisms by which dermatophytes cause cutaneous disease (50%).

b.What factors are important in host resistance and recovery from dermatophyte infection (50%).

  1. Discuss the morphology and function of the mast cell
  1. Answer FOUR (4) of the following
  1. (i) List the forms of IL-1 (interleukin 1) and cells of production (20%)

(ii)Describe its role in skin disease (45%)

(iii)Discuss the systemic consequences of excess production (35%)

  1. Describe superantigens and the means by which they induce disease, with particular reference to immune mediated disease
  1. Describe the phases of the keratinocyte cell cycle and the abnormalities that have been described in it in primary seborrhoea of American Cocker Spaniels
  1. Write short notes on sphingolipids
  1. Describe the structure, biosynthesis and degradation of elastin.
  1. Discuss the mechanism, control and role of apoptosis in normal immune function
  1. a. List the types and discuss the proposed pathogenesis of contact dermatitis (75%)

b.Briefly compare contact dermatitis in humans and dogs (25%).

END OF PAPER

FELLOWSHIP EXAMINATION JUNE/JULY 2001

VETERINARY DERMATOLOGY

PAPER 2

Perusal Time : 20 minutes

Time Allowed : FOUR (4) Hours after perusal

ANSWER FIVE (5) out of Six Questions Only

ALL QUESTIONS ARE OF EQUAL VALUE

Subsections of Questions are of equal value unless stated otherwise

  1. A 6 year old Thoroughbred stallion is presented with dermatitis on the pasterns. Describe and discuss the differential diagnoses and management of this case.
  1. Write short notes on FOUR (4) of the following
  1. Congenital hypotrichosis in cattle
  2. Lupoid dermatosis in German Short Haired Pointers
  3. Chediak-Higashi syndrome
  4. Sebaceous adenitis in the Poodle.
  5. Canine papillomavirus infection
  1. A 9 year old male cat is presented with chronic discharging tracts on the inguinal area and lateral abdomen. Discuss the differential diagnoses, investigation, treatment and prognosis of the case. Your answer should include a comparison of the cytology, histopathology and colony characteristics of the differentials.
  1. Write short notes on FOUR (4) of the following
  1. Paraneoplastic syndromes in the cat
  2. Facial eczema in sheep & cattle
  3. Dermatophyosis in cattle
  4. Diagnosis and management of dorsal pruritus in a colony of Guinea Pigs
  5. Bacterial skin disease in pigs
  1. a. Compare and contrast the pathogenesis, clinical presentation and diagnosis of pemphigus foliaceus in the dog and humans (60%).

b.Discuss the management of the condition in the dog (40%)

  1. Write short notes on FOUR (4) of the following compounds, including the mechanism of action, pharmacodynamics, toxicity and indications for use in dogs.
  1. Clindamycin
  2. Griseofulvin
  3. Azathioprine
  4. Pentoxyphylline
  5. Lomustine

END OF PAPER