PERSONALINFORMATION
Family name, First name: Zeybel, Müjdat
Date of birth: 30.04.1975
CURRENTPOSITION
10/2014 – 10/2016Instructor and Consultant GastroenterologistKoç University, School of Medicine
Istanbul, Turkey
EDUCATION
09/2011 – 09/2014PhD
Fibrosis Group, Newcastle University, UK
09/2010 – 10/2011Master of Research
Fibrosis Group, Newcastle University, UK
09/1992 – 06/1999MD
Hacettepe University, Ankara, Turkey
PREVIOUSPOSITIONS
12/2012 – 09/2014European Association for the Study of the Liver, Physician Scientist Sheila Sherlock Fellow, Newcastle University, UK
09/2011 – 08/2015PhD Student & GMC registered Medical Doctor
Fibrosis Group, Newcastle University, UK
06/2009 – 09/2010Visiting Researcher
Fibrosis Group, Newcastle University, UK
01/2006 – 06/2009Gastroenterology Clinical Fellow
Celal Bayar University Hospital, Turkey DokuzEylül University, Turkey Newcastle University, UK
04/2004 – 12/2005Physician
Sifa Hospital, Batman, Turkey
03/2004 – 03/2004Internal Medicine Residency
DokuzEylul University, Izmir Turkey
FELLOWSHIPSANDAWARDS
12/2015 – 12/2017YurdaDönüşAraştırma Burs Programı
TÜBİTAK
05/2015 – 05/2017Marie Curie Sklodowska
Individual Fellowship
European Commission, Horizon 2020
12/2012 – 09/2014European Association for the Study of Liver
Physician Scientist, Sheila Sherlock Fellow
09/2010 – 09/2014Overseas Research Scholarship
Newcastle University, UK
06/2009 – 09/2010Young Investigator Bursary, Turkish Association for the Study of the Liver
PEER-REVIEWED PUBLICATIONS
Zeybel M, Hardy T, Robinson SM, Fox C, Anstee QM, Ness T, Masson S, Mathers JC, French J, White S, Mann J. Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease.Clinical Epigenetics. 2015 Mar 14;7(1):25.
Zeybel M, Mann DA, Mann J. Epigenetic modifications as new targets for liver disease therapies.Journal of Hepatology. 2013; 59(6): 1349-53.
Zeybel M, Hardy T, Wong YK, Mathers JC, Fox CR, Gackowska A, Oakley F, Burt AD, Wilson CL, Anstee QM, Barter MJ, Masson S, Elsharkawy AM, Mann DA, Mann J. Multigenerational epigenetic adaptation of the hepatic wound-healing response.Nature Medicine. 2012;18(9): 1369-77
Perugorria MJ, Wilson CL, Zeybel M, Walsh M, Amin S, Robinson S, White SA, Burt AD, Oakley F, Tsukamoto H, Mann DA, Mann J. Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation.Hepatology. 2012; 56(3):1129-39.
Kasap E, Zeybel M, Aşık G, Ayhan S, Yüceyar H. Correlation among standard endoscopy, narrow band imaging, and histopathological findings in the diagnosis of nonerosive reflux disease.Journal of Gastrointestinal and Liver Disease. 2011; 20(2):127-30.
Kendrick SF, O'Boyle G, Mann J, Zeybel M, Palmer J, Jones DE, Day CP. Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis.Hepatology. 2010; 51(6):1988-97
Kobak AC, Zeybel M, Ayhan S, Aydin A, Kaya Y, Ellidokuz E.Gastric polypoidintramucosal carcinoma and an adjacently located leiomyoma at the cardia.Turk J Gastroenterol. 2008;19(2):114-6.
CelebiKobak A, Zeybel M, Ayhan S, Kara E, Ellidokuz E.Endoscopic submucosal resection of a rectal carcinoid tumor by cap aspiration - snare resection method.Turk J Gastroenterol. 2006;17(4):313-5.
Birlik M, Demir T, Zeybel M, Akar S, Onen F, Comlekci A, Tunca M, Akkoc N.
A case of recurrent pancreatitis due to hyperlipidemia misdiagnosed as familial Mediterranean fever.ClinRheumatol. 2004;23(6):559-61.
Cavdar C, Atay T, Zeybel M, Celik A, Ozder A, Yildiz S, Gulay Z, Camsari T.
Emergence of resistance in staphylococci after long-term mupirocin application in patients on continuous ambulatory peritoneal dialysis.AdvPerit Dial.2004;20:67-70.
Cavdar C, Zeybel M, Atay T, Sifil A, Sanlidag C, Gulay Z, Camsari T.The effects of once- or thrice-weekly mupirocin application on mupirocin resistance in patients on continuous ambulatory peritoneal dialysis--first 6 months' experience.AdvPerit Dial. 2004;20:62-6.
Epidermal growth factor receptor expression in human renal allograft biopsies: an immunohistochemical study.Sis B, Sarioglu S, Celik A, Zeybel M, Soylu A, Bora S.TransplImmunol. 2004;13(3):229-32.
Sarioğlu S, Sis B, Tuncer C, Celik A, Zeybel M, Soylu A, Gülay H.Tubular CD44 expression in renal allograft biopsies.Transplant Proc. 2004;36(1):92-4.
Zeybel M, Ozder A, Sanlidag C, Yildiz S, Cavdar C, Ersoy R, Celik A, Camsari T.The effects of weekly mupirocin application on infections in continuous ambulatory peritoneal dialysis patients.AdvPerit Dial. 2003;19:198-201.
PATENTS
Methods relating to identification of susceptibility to liver injury, PCT/GB2012/052714
- CONFERENCE PRESENTATIONS
2014The Liver Meeting, AASLD, Boston, US (Invited talk) Use of Epigenetics in DILI Research
2014British Association for the Study of the Liver Scientific Workshop Devon, UK (Invited talk)
Epigenetics and Liver Disease,
2014The International Liver Congress, EASL
London, UK (Invited talk-dual act)
The clinical evidence of epigenetic modifiers in liver fibrosis
2013The International Liver Congress, EASL Amsterdam, the Netherlands (Invited talk)
Recent highlights from the literature: ask the authors)
2013The International Liver Congress, EASL,
Amsterdam, The Netherlands (Invited short-talk)
Clinical application of epigenetics in liver fibrosis
2012The Liver Meeting, AASLD
Boston, US (Poster)
DZNep attenuates liver fibrosis by blocking EZH2 and H3K27 methylation.
2012British Association for the Study of the Liver
Scientific Workshop, Devon, UK (Oral presentation)
Protective adaptation to liver fibrosis by heritable epigenetic modifications.
2011The International Liver Congress, EASL,
Berlin, Germany
Protective adaptation to liver fibrosis in a single generation by heritable epigenetic modifications.