Research outputs
Listing of Research outputs
Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer
Traylor, M., Walker, J. L., Corrigan, A. A., Hernandez, M. A., Newhouse, S. J., Folarin, A. A., Patel, H., Ross, P. J., Sanderson, J. D., Spicer, J., Prescott, N. J., Mathew, C. G., Marinaki, A. M. & Lewis, C. M.1 May 2018In : PloS one.13, 5, 11 p., e0188911
Research output: Contribution to journal › Article
Exome sequencing and genotyping identify a rare variant in NLRP7 gene associated with ulcerative colitis
Onoufriadis, A., Stone, K., Katsiamides, A., Amar, A., Omar, Y., de Lange, K. M., Taylor, K., Barrett, J. C., Pollok, R., Hayee, BH., Mansfield, J. C., Sanderson, J. D., Simpson, M. A., Mathew, C. G.Prescott, N. J.1 Jan 2018In : Journal of Crohn's and Colitis.12, 3, p. 321-3266 p.
Research output: Contribution to journal › Article
Exome sequencing and genotyping identify a rare variant in NLRP7 gene associated with ulcerative colitis.
Onoufriadis, A., Stone, K., Katsiamides, A., Amar, A., Omar, Y., de Lange, K. M., Taylor, K., Barrett, J. C., Pollok, R., Hayee, BH., Mansfield, J. C., Sanderson, J. D., Simpson, M. A., Mathew, C. G.Prescott, N. J.4 Dec 2017In : Journal of Crohn's & colitis.12, 3, p. 321–326
Research output: Contribution to journal › Article
Fine-mapping inflammatory bowel disease loci to single-variant resolution
International Inflammatory Bowel Disease Genetics Consortium 13 Jul 2017In : NATURE.547, 7662, p. 173-1786 p.
Research output: Contribution to journal › Article
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
Reynolds, J. J. , Bicknell, L. S. , Carroll, P. , Higgs, M. R. , Shaheen, R. , Murray, J. E. , Papadopoulos, D. K. , Leitch, A. , Murina, O. , Tarnauskaitė, Ž. , Wessel, S. R. , Zlatanou, A. , Vernet, A. , von Kriegsheim, A. , Mottram, R. M. A. , Logan, C. V. , Bye, H. , Li, Y. , Brean, A. , Maddirevula, S. & 42 othersChallis, R. C., Skouloudaki, K., Almoisheer, A., Alsaif, H. S., Amar, A., Prescott, N. J., Bober, M. B., Duker, A., Faqeih, E., Seidahmed, M. Z., Al Tala, S., Alswaid, A., Ahmed, S., Al-Aama, J. Y., Altmüller, J., Al Balwi, M., Brady, A. F., Chessa, L., Cox, H., Fischetto, R., Heller, R., Henderson, B. D., Hobson, E., Nürnberg, P., Percin, E. F., Peron, A., Spaccini, L., Quigley, A. J., Thakur, S., Wise, C. A., Yoon, G., Alnemer, M., Tomancak, P., Yigit, G., Taylor, A. M. R., Reijns, M. A. M., Simpson, M. A., Cortez, D., Alkuraya, F. S., Mathew, C. G., Jackson, A. P. & Stewart, G. S.13 Feb 2017In : Nature Genetics.
Research output: Contribution to journal › Article
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
Luo, Y. , de Lange, K. M. , Jostins, L. , Moutsianas, L. , Randall, J. , Kennedy, N. A. , Lamb, C. A. , McCarthy, S. , Ahmad, T. , Edwards, C. , Serra, E. G. , Hart, A. , Hawkey, C. , Mansfield, J. C. , Mowat, C. , Newman, W. G. , Nichols, S. , Pollard, M. , Satsangi, J. , Simmons, A. & 10 othersTremelling, M., Uhlig, H., Wilson, D. C., Lee, J. C., Prescott, N. J., Lees, C. W., Mathew, C. G., Parkes, M., Barrett, J. C. & Anderson, C. A.9 Jan 2017In : Nature Genetics.49, 2, p. 186-192
Research output: Contribution to journal › Article
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
de Lange, K. M. , Moutsianas, L. , Lee, J. C. , Lamb, C. A. , Luo, Y. , Kennedy, N. A. , Jostins, L. , Rice, D. L. , Gutierrez-Achury, J. , Ji, S-G. , Heap, G. , Nimmo, E. R. , Edwards, C. , Henderson, P. , Mowat, C. , Sanderson, J. , Satsangi, J. , Simmons, A. , Wilson, D. C. , Tremelling, M. & 12 othersHart, A., Mathew, C. G., Newman, W. G., Parkes, M., Lees, C. W., Uhlig, H., Hawkey, C., Prescott, N. J., Ahmad, T., Mansfield, J. C., Anderson, C. A. & Barrett, J. C.9 Jan 2017In : Nature Genetics.49, 2, p. 256-261
Research output: Contribution to journal › Letter
International cancer seminars: A focus on esophageal squamous cell carcinoma
Murphy, G. , McCormack, V. , Abedi-Ardekani, B. , Arnold, M. , Camargo, M. C. , Dar, N. A. , Dawsey, S. M. , Etemadi, A. , Fitzgerald, R. C. , Fleischer, D. E. , Freedman, N. D. , Goldstein, A. M. , Gopa, S. , Hashemian, M. , Hu, N. , Hyland, P. L. , Kaimila, B. , Kamangar, F. , Malekzadeh, R. , Mathew, C. G.& 19 othersMenya, D., Mulima, G., M. Mwachiro, M., Mwasamwaja, A., Pritchett, N., Qiao, Y. L., Ribeiro-Pinto, L. F., Ricciardone, M., Schüz, J., Sitas, F., Taylor, P. R., Van Loon, K., Wang, S. M., Wei, W. Q., Wild, C. P., Wu, C., Abnet, C. C., Chanock, S. J. & Brennan, P.2017In : Annals of oncology : official journal of the European Society for Medical Oncology / ESMO.28, 9, p. 2086-20938 p.
Research output: Contribution to journal › Review article
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
Rivas, M. A. , Graham, D. , Sulem, P. , Stevens, C. , Desch, A. N. , Goyette, P. , Gudbjartsson, D. , Jonsdottir, I. , Thorsteinsdottir, U. , Degenhardt, F. , Mucha, S. , Kurki, M. I. , Li, D. , D'Amato, M. , Annese, V. , Vermeire, S. , Weersma, R. K. , Halfvarson, J. , Paavola-Sakki, P. , Lappalainen, M. & 31 othersLek, M., Cummings, B., Tukiainen, T., Haritunians, T., Halme, L., Koskinen, L. L. E., Ananthakrishnan, A. N., Luo, Y., Heap, G. A., Visschedijk, M. C., MacArthur, D. G., Ahmad, T., Anderson, C. A., Brant, S. R., Duerr, R. H., Silverberg, M. S., Cho, J. H., Palotie, A., Saavalainen, P., Kontula, K., Färkkilä, M., McGovern, D. P. B., Franke, A., Stefansson, K., Rioux, J. D., Xavier, R. J., Daly, M. J., Hawkey, C., Mathew, C., Prescott, N. & UK IBD Genetics Consortium9 Aug 2016In : Nature communications.7, 12342
Research output: Contribution to journal › Article
Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis
Mentzer, A., Nayee, S., Omar, Y., Hullah, E., Taylor, K., Goel, R., Bye, H., Shembesh, T., Elliott, T. R., Campbell, H., Patel, P., Nolan, A., Mansfield, J., Challacombe, S., Escudier, M., Mathew, C. G., Sanderson, J. D.Prescott, N. J.Jul 2016In : Inflammatory Bowel Diseases.22, 7, p. 1552-87 p.
Research output: Contribution to journal › Article
Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci
Saadati, H. R., Wittig, M., Helbig, I., Häsler, R., Anderson, C. A., Mathew, C. G., Kupcinskas, L., Parkes, M., Karlsen, T. H., Rosenstiel, P., Schreiber, S. & Franke, A. 1 Apr 2016In : BMC Medical Genetics.17, 1, 26
Research output: Contribution to journal › Article
Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease
Polley, S., Prescott, N., Nimmo, E., Veal, C., Vind, I., Munkholm, P., Fode, P., Mansfield, J., Skyt Andersen, P., Satsangi, J., G Mathew, C. & Hollox, E. J. 27 Jan 2016In : European journal of human genetics : EJHG.
Research output: Contribution to journal › Article
The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis
Robinson, P. C. , Leo, P. J. , Pointon, J. J. , Cremin, K. , Bradbury, L. A. , Donnelly (chair), P. , Barroso (deputy Chair), I. , M Blackwell, J. , Bramon, E. , Brown, M. A. , Casas, J. P. , Corvin, A. , Deloukas, P. , Duncanson, A. , Jankowski, J. , Markus, H. S. , Mathew, C. G. , Palmer, C. N. , Plomin, R. , Rautanen, A. & 59 othersSawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Donnelly, P., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., Mccann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Barroso, I., Deloukas, P., Mathew (chair), C. G., Blackwell, J. M., Brown, M. A., Corvin, A., Spencer, C. C. A., Mccloskey, E., Eisman, J., Jones, G., Nicholson, G., Eastell, R., Sambrook, P., Prince, R., Dennison, E., Reid, I., Wark, J., Stebbings, S., Harrison, A. A., Evans, D. M., Duncan, E. L., Wordsworth, B. P. & Brown, M. A.26 Nov 2015In : GENES AND IMMUNITY.17, 1, p. 46-51
Research output: Contribution to journal › Article
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank
Wain, L. V. , Shrine, N. , Miller, S. , Jackson, V. E. , Ntalla, I. , Artigas, M. S. , Billington, C. K. , Kheirallah, A. K. , Allen, R. , Cook, J. P. , Probert, K. , Obeidat, M. , Bossé, Y. , Hao, K. , Postma, D. S. , Paré, P. D. , Ramasamy, A. , Mägi, R. , Mihailov, E. , Reinmaa, E. & 138 othersMelén, E., O'Connell, J., Frangou, E., Delaneau, O., Freeman, C., Petkova, D., McCarthy, M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I., Hansell, A. L., Thomson, N. C., Zeggini, E., Morris, A. P., Marchini, J., Strachan, D. P., Tobin, M. D., Hall, I. P., Farrall, M., Barroso, I., Anderson, C. A., Botía, J., Vandrocova, J., Guelfi, S., D'Sa, K., Ryten, M., Trabzuni, D., Matarin, M., Hardy, J. A., Weale, M. E., Varghese, V., Forabosco, P., Farmer, A., McGuffin, P., Zgaga, L., Wilson, J. F., Wild, S. H., Campbell, H., Rudan, I., Smith, C., Walker, R., Liu, J. Z., Tozzi, F., Muglia, P., Waterworth, D. M., Pillai, S. G., Yuan, X., Mooser, V., Middleton, L., Kooner, J., Chambers, J. C., Berrettini, W., Knouff, C. W., Waeber, G., Vollenweider, P., Preisig, M., Wareham, N. J., Zhao, J. H., Loos, R. J. F., Khaw, K. T., Grundy, S., Barter, P., Mahley, R., Kesaniemi, A., McPherson, R., Vincent, J. B., Strauss, J., Kennedy, J. L., Day, R., Matthews, K., Bakke, P., Gulsvik, A., Lucae, S., Ising, M., Brueckl, T., Horstmann, S., Wichmann, H. E., Rawal, R., Wichmann, H. E., Lamina, C., Dahmen, N., Polasek, O., Kolcic, I., Huffman, J., Campbell, S., Vitart, V., Hayward, C., Wright, A. F., Burnett, M. S., Devaney, J. M., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Epstein, S., Reilly, M. P., Li, M., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Rader, D. J., Ellinghaus, D., Lieb, W., Franke, A., Uda, M., Busonero, F., Terracciano, A., Schlessinger, D., Xiao, X., Scheet, P., St Clair, D., Rujescu, D., Abecasis, G. R., Grabe, H. J., Teumer, A., Völzke, H., Petersmann, A., John, U., Wright, B. J., Thompson, J. R., Balmforth, A. J., Hall, A. S., Samani, N. J., Ahmad, T., Mathew, C. G., Parkes, M., Satsangi, J., Caulfield, M., Munroe, P. B., Dominiczak, A., Worthington, J., Thomson, W., Eyre, S., Barton, A. & Francks, C.Oct 2015In : The Lancet Respiratory Medicine.3, 10, p. 769-78113 p.
Research output: Contribution to journal › Article
Lamina propria macrophage phenotypes in relation to Escherichia coli in Crohn's disease
Elliott, T. R., Rayment, N. B., Hudspith, B., Hands, R. E., Taylor, K., Parkes, G. C., Prescott, N. J., Petrovska, L., Hermon-Taylor, J., Brostoff, J., Boussioutas, A., Mathew, C. G., Bustin, S. A. & Sanderson, J. D.3 Jul 2015In : BMC GASTROENTEROLOGY.15, 75
Research output: Contribution to journal › Article
Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants
Malik, R. , Freilinger, T. , Winsvold, B. S. , Anttila, V. , Vander Heiden, J. , Traylor, M. , De Vries, B. , Holliday, E. G. , Terwindt, G. M. , Sturm, J. , Bis, J. C. , Hopewell, J. C. , Ferrari, M. D. , Rannikmae, K. , Wessman, M. , Kallela, M. , Kubisch, C. , Fornage, M. , Meschia, J. F. , Lehtimaki, T. & 105 othersSudlow, C., Clarke, R., Chasman, D. I., Mitchell, B. D., Maguire, J., Kaprio, J., Farrall, M., Raitakari, O. T., Kurth, T., Ikram, M. A., Reiner, A. P., Longstreth, W. T., Rothwell, P. M., Strachan, D. P., Sharma, P., Seshadri, S., Quaye, L., Cherkas, L., Schurks, M., Rosand, J., Ligthart, L., Boncoraglio, G. B., Davey Smith, G., Van Duijn, C. M., Stefansson, K., Worrall, B. B., Nyholt, D. R., Markus, H. S., Van Den Maagdenberg, A. M. J. M., Cotsapas, C., Zwart, J. A., Palotie, A., Dichgans, M., Thorsteinsdottir, U., Destefano, A. L., Levi, C., Gretarsdottir, S., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. NA., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath F, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. CA., Band, G., Bellengues, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkind, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronv, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., Mccann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Rickette, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Gormley, P., Bettella, F., Mcmahon, G., Todt, U., Palta, P., Hamalainen, E., Steinberg, S., Stefansson, H., Farkkila, M., Artto, V., Kaunisto, M. A., Schoenen, J., Frants, R. R., Borck, G., Gobel, H., Heinze, A., Heinze-kuhn, K. & Muller-myhsok, B.26 May 2015In : Neurology.84, 21, p. 2132-214514 p., 21
Research output: Contribution to journal › Article
Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes
Prescott, N. J. , Lehne, B. , Stone, K. , Lee, J. C. , Taylor, K. , Knight, J. , Papouli, E. , Mirza, M. M. , Simpson, M. A. , Spain, S. L. , Lu, G. , Fraternali, F. , Bumpstead, S. J. , Gray, E. , Amar, A. , Bye, H. , Green, P. , Chung-Faye, G. , Hayee, BH. , Pollok, R. & 10 othersSatsangi, J., Parkes, M., Barrett, J. C., Mansfield, J. C., Sanderson, J., Lewis, C. M., Weale, M. E., Schlitt, T., Mathew, C. G. & UK IBD Genetics Consortium11 Feb 2015In : PL o S Genetics.11, 2, 19 p., e1004955
Research output: Contribution to journal › Article
Defective macrophage handling of Escherichia coli in Crohn's disease
Elliott, T. R., Hudspith, B. N., Rayment, N. B., Prescott, N. J., Petrovska, L., Hermon-Taylor, J., Brostoff, J., Boussioutas, A., Mathew, C. G.Sanderson, J. D.2015In : Journal of Gastroenterology and Hepatology.
Research output: Contribution to journal › Article
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins
Postmus, I. , Trompet, S. , Deshmukh, H. A. , Barnes, M. R. , Li, X. , Warren, H. R. , Chasman, D. I. , Zhou, K. , Arsenault, B. J. , Donnelly, L. A. , Wiggins, K. L. , Avery, C. L. , Griffin, P. , Feng, Q. , Taylor, K. D. , Li, G. , Evans, D. S. , Smith, A. V. , De Keyser, C. E. , Johnson, A. D. & 142 othersDe Craen, A. J. M., Stott, D. J., Buckley, B. M., Ford, I., Westendorp, R. G. J., Eline Slagboom, P., Sattar, N., Munroe, P. B., Sever, P., Poulter, N., Stanton, A., Shields, D. C., O???brien, E., Shaw-hawkins, S., Ida Chen, Y., Nickerson, D. A., Smith, J. D., Pierre Dub??, M., Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, J. J. P., Mckeigue, P. M., Betteridge, J., Neil, A., Durrington, P. N., Doney, A., Carr, F., Morris, A., Mccarthy, M. I., Groop, L., Ahlqvist, E., Bis, J. C., Rice, K., Smith, N. L., Lumley, T., Whitsel, E. A., St??rmer, T., Boerwinkle, E., Ngwa, J. S., O???donnell, C. J., Vasan, R. S., Wei, W., Wilke, R. A., Liu, C., Sun, F., Guo, X., Heckbert, S. R., Post, W., Sotoodehnia, N., Arnold, A. M., Stafford, J. M., Ding, J., Herrington, D. M., Kritchevsky, S. B., Eiriksdottir, G., Launer, L. J., Harris, T. B., Chu, A. Y., Giulianini, F., Macfadyen, J. G., Barratt, B. J., Nyberg, F., Stricker, B. H., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Emilsson, V., Franco, O. H., Ridker, P. M., Gudnason, V., Liu, Y., Denny, J. C., Ballantyne, C. M., Rotter, J. I., Adrienne Cupples, L., Psaty, B. M., Palmer, C. N. A., Tardif, J., Colhoun, H. M., Hitman, G., Krauss, R. M., Wouter Jukema, J., Caulfield, M. J., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Donnelly, P., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., Mccann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Barroso, I., Deloukas, P., Mathew, C. G., Blackwell, J. M., Brown, M. A., Corvin, A., Mccarthy, M. I. & Spencer, C. C. A.28 Oct 2014In : Nature Communications.5, 5068
Research output: Contribution to journal › Article
The correlation between reading and mathematics ability at age twelve has a substantial genetic component
Davis, O. S. P. , Band, G. , Pirinen, M. , Haworth, C. M. A. , Meaburn, E. L. , Kovas, Y. , Harlaar, N. , Docherty, S. J. , Hanscombe, K. B. , Trzaskowski, M. , Curtis, C. J. C. , Strange, A. , Freeman, C. , Bellenguez, C. , Su, Z. , Pearson, R. , Vukcevic, D. , Langford, C. , Deloukas, P. , Hunt, S. & 31 othersGray, E., Dronov, S., Potter, S. C., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, S. J., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J. A. Z., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Barroso, I., Peltonen, L., Dale, P. S., Petrill, S. A., Schalkwyk, L. S., Craig, I. W., Lewis, C. M., Price, T. S., Plomin, R. & Wellcome Trust Case Control Consortium8 Jul 2014In : Nature Communications.5, 6 p., 4204
Research output: Contribution to journal › Article
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation
Bramon, E. , Pirinen, M. , Strange, A. , Lin, K. , Freeman, C. , Bellenguez, C. , Su, Z. , Band, G. , Pearson, R. , Vukcevic, D. , Langford, C. , Deloukas, P. , Hunt, S. , Gray, E. , Dronov, S. , Potter, S. C. , Tashakkori-Ghanbaria, A. , Edkins, S. , Bumpstead, S. J. , Arranz, M. J.& 31 othersBakker, S., Bender, S., Bruggeman, R., Cahn, W., Chandler, D., Collier, D. A., Crespo-Facorro, B., Dazzan, P., de Haan, L., Di Forti, M., Dragović, M., Giegling, I., Hall, J., Iyegbe, C., Jablensky, A., Kravariti, E., Mata, I., McDonald, C., Pariante, C. M., Picchioni, M., Shaikh, M., Toulopoulou, T., Van Os, J., Walshe, M., Mathew, C. G., Plomin, R., Trembath, R. C., Lewis, C. M., Murray, R. M., Powell, J. & Psychosis Endophenotypes International Consortium1 Mar 2014In : Biological Psychiatry.75, 5, p. 386-39712 p.
Research output: Contribution to journal › Article
A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility
Damotte, V. , Guillot-noel, L. , Patsopoulos, N. A. , Madireddy, L. , El Behi, M. , Ban, M. , Baranzini, S. , Barcellos, L. , Beecham, G. , Beecham, A. , Bernardinelli, L. , Booth, D. , Bos, S. , Buck, D. , Bush, W. , Comabella, M. , Compston, A. , Cotsapas, C. , Cournu-rebeix, I. , Cree, B. & 118 othersD'alfonso, S., Daly, M., Damotte, V., Davis, M., De Bakker, P., De Jager, P. L., Dubois, B., Esposito, F., Fontaine, B., Goris, A., Gourraud, P., Green, T., Gulowsen Celius, E., Hadjixenofontos, A., Hafler, D., Haines, J., Flinstad, H. F., Hauser, S., Hawkins, C., Hemmer, B., Hillert, J., Hintzen, R., Horáková, D., Ivinson, A. J., Kemppinen, A., Kira, J., Kockum, I., Lincoln, R., Martin, R., Martinelli Boneschi, F., Mccauley, J. L., Mero, I., Oksenberg, J., Olsson, T., Oturai, A., Palotie, A., Patsopoulos, N., Pericak-vance, M., Rioux, J., Saarela, J., Sawcer, S., Schnetz-boutaud, N., Sellebjerg, F., Soendergaard, H., Soelberg Sorensen, P., Spurkland, A., Stankovich, J., Stewart, G., Taylor, B., Ticca, A., West, S., Zipp, F., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Donnelly, P., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., Mccann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M. J., Weston, P., Widaa, S., Whittaker, P., Barroso, I., Deloukas, P., Dilthey, A., Leslie, S., Moutsianas, L., Perez, M. L., Mcvean, G., Mathew, C. G., Blackwell, J. M., Brown, M. A., Corvin, A., Mccarthy, M. I., Spencer, C. C. A., De Jager, P. L., Baranzini, S. E., Cournu-rebeix, I. & Fontaine, B.Mar 2014In : GENES AND IMMUNITY.15, 2, p. 126-1327 p., N/A
Research output: Contribution to journal › Article
Genome-wide estimates of inbreeding in unrelated individuals and their association with cognitive ability
Power, R. , Nagoshi, C. , Defries, J. C. , Donnelly, P. , Barroso, I. , Blackwell, J. M. , Bramon, E. , Brown, M. A. , Casas, J. P. , Corvin, A. , Deloukas, P. , Duncanson, A. , Jankowski, J. , Markus, H. S. , Mathew, C. G. , Palmer, C. N. , Rautanen, A. , Sawcer, S. J. , Trembath, R. C. , Viswanathan, A. C.& 41 othersWood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Donnelly, P., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., Mccann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Barroso, I., Deloukas, P., Mathew, C. G., Blackwell, J. M., Brown, M. A., Corvin, A., Spencer, C. C. A. & Plomin, R.Mar 2014In : European Journal of Human Genetics.22, 3, p. 386-3905 p.
Research output: Contribution to journal › Article
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
Ripke, S. , O'dushlaine, C. , Chambert, K. , Moran, J. L. , K??hler, A. K. , Akterin, S. , Bergen, S. E. , Collins, A. L. , Crowley, J. J. , Fromer, M. , Kim, Y. , Lee, S. H. , Magnusson, P. K. E. , Sanchez, N. , Stahl, E. A. , Williams, S. , Wray, N. R. , Xia, K. , Bettella, F. , Borglum, A. D. & 15 othersBulik-sullivan, B. K., Cormican, P., Craddock, N., De Leeuw, C., Durmishi, N., Gill, M., Lin, K., Neale, B. M., Powell, J., Riley, B. P., Walters, J. T., Multicenter Genetic Studies of Schizophrenia Consortium, Psychosis Endophenotypes International Consortium, Wellcome Trust Case Consortium 2 & Purcell, S.Oct 2013In : Nature Genetics.45, 10, p. 1150-115910 p.
Research output: Contribution to journal › Article
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Ellinghaus, D. , Folseraas, T. , Holm, K. , Ellinghaus, E. , Melum, E. , Balschun, T. , Laerdahl, J. K. , Shiryaev, A. , Gotthardt, D. N. , Weismüller, T. J. , Schramm, C. , Wittig, M. , Bergquist, A. , Björnsson, E. , Marschall, H-U. , Vatn, M. , Teufel, A. , Rust, C. , Gieger, C. , Wichmann, H-E. & 17 othersRunz, H., Sterneck, M., Rupp, C., Braun, F., Weersma, R. K., Wijmenga, C., Ponsioen, C. Y., Mathew, C. G., Rutgeerts, P., Vermeire, S., Schrumpf, E., Hov, J. R., Manns, M. P., Boberg, K. M., Schreiber, S., Franke, A. & Karlsen, T. H.Sep 2013In : Hepatology.58, 3, p. 1074-108310 p., N/A
Research output: Contribution to journal › Article
Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies
Ellinghaus, D. , Zhang, H. , Zeissig, S. , Lipinski, S. , Till, A. , Jiang, T. , Stade, B. , Bromberg, Y. , Ellinghaus, E. , Keller, A. , Rivas, M. A. , Skieceviciene, J. , Doncheva, N. T. , Liu, X. , Liu, Q. , Jiang, F. , Forster, M. , Mayr, G. , Albrecht, M. , Haesler, R. & 41 othersBoehm, B. O., Goodall, J., Berzuini, C. R., Lee, J., Andersen, V., Vogel, U., Kupcinskas, L., Kayser, M., Krawczak, M., Nikolaus, S., Weersma, R. K., Ponsioen, C. Y., Sans, M., Wijmenga, C., Strachan, D. P., McAardle, W. L., Vermeire, S., Rutgeerts, P., Sanderson, J., Mathew, C. G., Vatn, M. H., Wang, J., Noethen, M. M., Duerr, R. H., Buening, C., Brand, S., Glas, J., Winkelmann, J., Illig, T., Latiano, A., Annese, V., Halfvarson, J., D'Amato, M., Daly, M. J., Nothnagel, M., Karlsen, T. H., Subramani, S., Rosenstiel, P., Schreiber, S., Parkes, M. & Franke, A.Aug 2013In : Gastroenterology.145, 2, p. 339-3479 p.
Research output: Contribution to journal › Article
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
Hunt, K. A. , Mistry, V. , Bockett, N. A. , Ahmad, T. , Ban, M. , Barker, J. N. , Barrett, J. C. , Blackburn, H. , Brand, O. , Burren, O. , Capon, F. , Compston, A. , Gough, S. C. L. , Jostins, L. , Kong, Y. , Lee, J. C. , Lek, M. , MacArthur, D. G. , Mansfield, J. C. , Mathew, C. G.& 17 othersMein, C. A., Mirza, M., Nutland, S., Onengut-Gumuscu, S., Papouli, E., Parkes, M., Rich, S. S., Sawcer, S., Satsangi, J., Simmonds, M. J., Trembath, R. C., Walker, N. M., Wozniak, E., Todd, J. A., Simpson, M. A., Plagnol, V. & van Heel, D. A.13 Jun 2013In : NATURE.498, 7453, p. 232-2354 p.
Research output: Contribution to journal › Letter
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis
Fakiola, M. , Strange, A. , Cordell, H. J. , Miller, E. N. , Pirinen, M. , Su, Z. , Mishra, A. , Mehrotra, S. , Monteiro, G. R. , Band, G. , Bellenguez, C. , Dronov, S. , Edkins, S. , Freeman, C. , Giannoulatou, E. , Gray, E. , Hunt, S. E. , Lacerda, H. G. , Langford, C. , Pearson, R. & 31 othersPontes, N. N., Rai, M., Singh, S. P., Smith, L., Sousa, O., Vukcevic, D., Bramon-Bosch, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Wilson, M. E., Deloukas, P., Peltonen, L., Christiansen, F., Witt, C., Jeronimo, S. M. B., Sundar, S., Spencer, C. C. A., Blackwell, J. M. & LeishGEN Consortium1 Feb 2013In : Nature Genetics.45, 2, p. 208-2136 p.
Research output: Contribution to journal › Letter
Bayesian refinement of association signals for 14 loci in 3 common diseases
Maller, J. B. , McVean, G. , Byrnes, J. , Vukcevic, D. , Palin, K. , Su, Z. , Howson, J. M. M. , Auton, A. , Myers, S. , Morris, A. , Pirinen, M. , Brown, M. A. , Burton, P. R. , Caulfield, M. J. , Compston, A. , Farrall, M. , Hall, A. S. , Hattersley, A. T. , Hill, A. V. S. , Mathew, C. G.& 18 othersPembrey, M., Satsangi, J., Stratton, M. R., Worthington, J., Craddock, N., Hurles, M., Ouwehand, W., Parkes, M., Rahman, N., Duncanson, A., Todd, J. A., Kwiatkowski, D. P., Samani, N. J., Gough, S. C. L., McCarthy, M. I., Deloukas, P., Donnelly, P. & Wellcome Trust Case Control ConsortiumDec 2012In : Nature Genetics.44, 12, p. 1294-13018 p.
Research output: Contribution to journal › Article
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Tsoi, L. C. , Spain, S. L. , Knight, J. , Ellinghaus, E. , Stuart, P. E. , Capon, F. , Ding, J. , Li, Y. , Tejasvi, T. , Gudjonsson, J. E. , Kang, H. M. , Allen, M. H. , McManus, R. , Novelli, G. , Samuelsson, L. , Schalkwijk, J. , Ståhle, M. , Burden, A. D. , Smith, C. H. , Cork, M. J. & 31 othersEstivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Onoufriadis, A., Weale, M. E., Campbell, L. E., Mathew, C. G., Plomin, R., Viswanathan, A. C., Gray, E., Weston, P., Barker, J. N. W. N., Trembath, R. C. & Collaborative Association Study of Psoriasis (CASP)Dec 2012In : Nature Genetics.44, 12, p. 1341-13488 p.
Research output: Contribution to journal › Article
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Jostins, L. , Ripke, S. , Weersma, R. K. , Duerr, R. H. , McGovern, D. P. , Hui, K. Y. , Lee, J. C. , Schumm, L. P. , Sharma, Y. , Anderson, C. A. , Essers, J. , Mitrovic, M. , Ning, K. , Cleynen, I. , Theatre, E. , Spain, S. L. , Raychaudhuri, S. , Goyette, P. , Wei, Z. , Abraham, C. & 31 othersAchkar, J-P., Ahmad, T., Amininejad, L., Ananthakrishnan, A. N., Andersen, V., Andrews, J. M., Baidoo, L., Balschun, T., Bampton, P. A., Bitton, A., Boucher, G., Brand, S., Büning, C., Cohain, A., Cichon, S., D'Amato, M., De Jong, D., Devaney, K. L., Dubinsky, M., Edwards, C., Ellinghaus, D., Ferguson, L. R., Franchimont, D., Fransen, K., Gearry, R., Georges, M., Gieger, C., Prescott, N. J., Sanderson, J., Mathew, C. G. & International IBD Genetics Consortium (IIBDGC)1 Nov 2012In : NATURE.491, 7422, p. 119-1246 p.
Research output: Contribution to journal › Article
Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population