Editor Profile

Monica Rinaldi

Institute of Translational Pharmacology

Department of BioMedicine

National Research Council, Italy

Contact

Institute of Translational Pharmacology (IFT)

National ResearchCouncil (CNR)

Via Fosso del Cavaliere 100

00133 Rome, Italy

Phone: (+39) 0649934219

Fax: (+39) 0649934257

E-mail:

Commitments and Accolades

  • Editor (Invited Handling Editor) for the volume “DNA Vaccines”, in 'Methods in Molecular Biology' series published by Humana Press, Springer publishing group (2012-present)
  • Member, Board of Editors, Novus International Journal of Biotechnology & Bioscience, (Novus Scientia Journals, (2012-present)
  • Associate Editor, Journal of Alzheimer Disease, (IOS Press publication) (2011)
  • Member, Institute Committee, Institute of Translational Pharmacology, CNR, (2010-present)
  • Appointed by the Director, Institute of Translational Pharmacology, CNR, in the Commission of reviewers for the selection of Technicians, Young Investigators, Senior Investigators, Researchers (2010-present)
  • Appointed by the Board of Directors, CNR, in the list of internal expert for the composition of committees in the national process of recruiting staff researcher and technologist (2009-present)
  • Member, Institute Committee, Institute of Neurobiology and Molecular Medicine, CNR, (2009-2010)
  • Appointed by the Director, Institute of Neurobiology and Molecular Medicine, CNR, in the Commission of reviewers for the selection of Young Investigators, Senior Investigators, Researchers (2003-2009)

Current Research

  • In vivo naked gene transfer into muscle
  • Development of specific multigenic plasmid vectors
  • Pre-clinical protocols by systemic delivery of recombinant proteins in animal models of human diseases.
  • Anti tumor DNA vaccines in indolent B cell Lymphoma and colon cancer
  • Pre-clinical protocols of genetic immunization against tumor antigens
  • Combined therapeutic protocols (vaccination+immunotherapy+chemotherapy)
  • Development of innovative vaccine formulations for anticancer therapy and/or prevention, intended for clinical application

Biography

Monica Rinaldiwas born in 1964 in Rome, Italy. After graduating with full honours in Biology at the University of Rome "La Sapienza", she obtained a Ph.D. in Biotechnology. From 1995 to 2000 she was a Post-Doctoral Fellow in Molecular Medicine at the Institute of Neurobiology and Molecular Medicine, National Research Council (CNR), ITALY. She was appointed as Assistant Professor of General Pathology at University Campus Bio-Medico of Rome, School of Medicine (1996-2001), and Professor of Molecular Biology at University Campus Bio-Medico of Rome, School of Engineering, Degree in Biomedical Engineering (1999-2000).Since 2001 she is Research Scientist at the Department of BioMedicine, CNR. She is Head of Laboratory of Medical Biotechnologyat the Institute of Translational Pharmacology (IFT),CNR. Dr. Rinaldi is the author of more than 50 peer reviewed scientific publications, including original research articles, book chapters and invited reviews. She is co-inventor of U.S. patents (USPTO) and Principal Investigator of several grants related to biotechnology applications in medicine. She is peer reviewer for several scientific journals. Her majorfield areas areMolecular Pathology, Experimental Oncology, Immunotherapy and research interests focus on the pre-clinical development of innovative drug formulations and protocols for advanced therapies(gene therapy and DNA vaccination).

Selected Recent Publications

Epitope-driven DNA vaccine design employing immunoinformatics against B-cell lymphoma: a biotech's challenge

Iurescia S, Fioretti D, Fazio VM, Rinaldi M

Biotechnology Advances; volume 30; pages 372-383; Published: 2012

Design and pre-clinical development of epitope-based DNA vaccines against B-cell lymphoma

Iurescia S, Fioretti D, Fazio VM, Rinaldi M.

Current Gene Therapy; volume 11, issue 5; pages 414-22; Published: 2011

Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival in a mouse model of lymphoma.

Iurescia S, Fioretti D, Pierimarchi P, Signori E, Zonfrillo M, Tonon G, Fazio VM, Rinaldi M.

Journal of Biomedicine and Biotechnology; volume 2010; Published: 2010

Anti-tumor immunity induced by CDR3-based DNA vaccination in a murine B-cell lymphoma model

Rinaldi M, Fioretti D, Iurescia S, Signori E, Pierimarchi P, Seripa D, Tonon G, Fazio VM.

Biochemical and Biophysical Research Communications; volume 370; pages 279-84; Published: 2008