Dr. Galileo Escobedo, Ph.D.
Inflammatory pathways in NAFLD and type 2 Diabetes
Laboratory for Proteomics and Metabolomics
Research Division
General Hospital of Mexico
National Institutes of Health
Mexico City, 06726
Mexico
Phone: +52-55-2789-2000, Ext. 5646
Fax: +52-55-5623-2699
E-mail: ,
Biosketch
Galileo Escobedo (1978) studied Experimental Biology in the Health Science Division of the Metropolitan University of Mexico. After this, he started his Ph.D. education in the Biomedical Research Ph.D. program, at the Department of Immunology of the Biomedical Research Institute of the National Autonomous University of Mexico. In 2006, he moved to Dr. Craig Robert’s lab at the University of Strathclyde, Glasgow, Scotland. He received his Ph.D. (2008) working on the molecular and cellular mechanisms involved in the relationship between the immune response and the neuro-endocrine system during health and disease. Immediately after, he moved to Dr. Ignacio Camacho’s lab at the School of Chemistry of the National University of Mexico, where he studied the role of hormones in the improvement of the inflammatory immune response against intestinal pathogens. At the end of 2009, he incorporated at the Unit of Experimental Medicine, School of Medicine, National University of Mexico, General Hospital of Mexico, National Institutes of Health, where he works on the topics concerning the role of the inflammatory response in developing obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD).
Dr. Escobedo’s current research topics focus on the role of proinflammatory cytokines and chemokines in mediating recruitment of classically-activated macrophages into the adipose tissue and liver of morbidly obese patients, as well as type 2 diabetic patients. He is also interested in designing immunotherapy approaches for the anti-inflammatory control of type 2 diabetes and NAFLD, using the high-fat diet mouse as a study model. Of special interest is the designing of early non-invasive diagnosis methods for NAFLD, based on the study of spectroscopic signals such as diffuse reflectance and fluorescence in patients with fatty liver disease and paraffin-preserved human hepatic specimens by working with physics and engineers in the field of electronic and optic systems.
Since his Ph.D. training, Dr. Escobedo has been also involved in teaching activities for students of medical, biomedical, and biochemical sciences, currently supervising more than 15 students of bachelor, MSc, and PhD programs as well as postdoctoral fellows.He has been awarded 4 research grants from the Mexican Council of Science and Technology (CONACYT) and one grant from the Marie Curie International Research Staff Exchange Scheme with the 7th European Community Framework Program. Dr. Escobedo has published more than 50 original research papers and reviews in JCR international journals and written several book chapters related to the inflammatory response, obesity, type 2 diabetes, and liver disease.
Research lines
1)Relationship of proinflammatory cytokines, chemokines, and macrophages with the development of insulin resistance and NAFLD in obese individuals.
2)Designing of novel immunotherapy approaches for preventing type 2 diabetes and NAFLD.
3)Designing of non-invasive spectroscopic methods for NAFLD diagnosis.
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