Research outputs
Listing of Research outputs
Positive airway pressure devices for the management of breathlessness
D'Cruz, R. F., Kaltsakas, G., Suh, E-S., Murphy, P. B.Hart, N.Sep 2018In : Current Opinion in Supportive and Palliative Care.12, 3, p. 246-2527 p.
Research output: Contribution to journal › Article
Patients, caregivers and health system costs of home ventilation
Murphy, P. B.Douiri, A.Jul 2018In : Thorax.73, 7
Research output: Contribution to journal › Editorial
Nutrition and Exercise Rehabilitation in Obesity hypoventilation syndrome (NERO): a pilot randomised controlled trial
Mandal, S., Suh, E. S., Harding, R., Vaughan-France, A., Ramsay, M., Connolly, B., Bear, D. E., MacLaughlin, H., Greenwood, S. A., Polkey, M. I., Elliott, M., Chen, T., Douiri, A., Moxham, J., Murphy, P. B.Hart, N.1 Jan 2018In : Thorax.73, 1, p. 62-698 p.
Research output: Contribution to journal › Article
Overnight auto-adjusting continuous airway pressure+standard care compared with standard care alone in the prevention of morbidity in sickle cell disease phase II (POMS2b): Study protocol for a randomised controlled trial
Howard, J. , Slee, A. E. , Skene, S. , Inusa, B. , Kawadler, J. , Downes, M. , Gavlak, J. , Koelbel, M. , Stotesbury, H. , Chorozoglou, M. , Tebbs, S. , Chakravorty, S. , Awogbade, M. , Rees, D. C. , Gupta, A. , Murphy, P. B. , Hart, N. , Sahota, S. , Nwosu, C. , Gwam, M. & 10 othersSaunders, D., Muthurangu, V., Barber, N., Ako, E., Thein, S. L., Marshall, M., Reading, I. C., Cheng, M. Y. E., Kirkham, F. J. & Liossi, C.2018In : Trials.19, 1, 55
Research output: Contribution to journal › Article
S38 Home mechanical ventilation (hmv) and home oxygen therapy (hot) following an acute exacerbation of copd in patients with persistent hypercapnia: predicting 1 year admission-free survival in the hot-hmv uk trial
Murphy, PB., Arbane, G., Bisquera, A.Hart, N.1 Dec 2017In : Thorax.72, Suppl 3, p. A26
Research output: Contribution to journal › Article
A descriptive study of the characteristics of older adults with sickle cell disease
Khan, A. B., Kesse-Adu, R., Breen, C., Murphy, P. B., Chambers, J., Holmes, P. & Howard, J. 20 Nov 2017In : American Journal of Hematology.
Research output: Contribution to journal › Letter
Prospective observational cohort study of patients with weaning failure admitted to a specialist weaning, rehabilitation and home mechanical ventilation centre
Mifsud Bonnici, D., Sanctuary, T., Warren, A., Murphy, P. B., Steier, J., Marino, P., Pattani, H., Creagh-Brown, B. C. & Hart, N.8 Mar 2016In : BMJ open.6, 3, p. e010025
Research output: Contribution to journal › Article
Parasternal electromyography to determine the relationship between patient-ventilator asynchrony and nocturnal gas exchange during home mechanical ventilation set-up
Ramsay, M., Mandal, S., Suh, E., Steier, J., Douiri, A., Murphy, P. B., Polkey, M., Simonds, A. & Hart, N.1 Oct 2015In : Thorax.70, 10, p. 946-9527 p.
Research output: Contribution to journal › Article
Prevention of Morbidity in sickle cell disease - qualitative outcomes, pain and quality of life in a randomised cross-over pilot trial of overnight supplementary oxygen and auto-adjusting continuous positive airways pressure (POMS2a): Study protocol for a randomised controlled trial
Howard, J., Inusa, B., Liossi, C., Jacob, E., Murphy, P. B., Hart, N., Gavlak, J., Sahota, S., Chorozoglou, M., Nwosu, C., Gwam, M., Gupta, A., Rees, D. C., Thein, S. L., Reading, I. C., Kirkham, F. J. & Cheng, M. Y. E. 25 Aug 2015In : Trials.16, 1, 12 p., 376
Research output: Contribution to journal › Article
Neural respiratory drive predicts clinical deterioration and safe discharge in exacerbations of COPD
Suh, E-S., Mandal, S., Harding, R., Ramsay, M., Kamalanathan, M., Henderson, K., O'Kane, K., Douiri, A., Hopkinson, N. S., Polkey, M. I., Rafferty, G., Murphy, P. B., Moxham, J.Hart, N.20 Jul 2015In : Thorax.70, 12, p. 1123-11308 p.
Research output: Contribution to journal › Article
Medium-term cost-effectiveness of an automated non-invasive ventilation outpatient set-up versus a standard fixed level non-invasive ventilation inpatient set-up in obese patients with chronic respiratory failure: a protocol description
Mandal, S., Arbane, G., Murphy, P., Elliott, M. W., Janssens, J. P., Pepin, J. L., Muir, J. F., Cuvelier, A., Polkey, M., Parkin, D., Douiri, A.Hart, N.23 Apr 2015In : BMJ open.5, 4, 7 p., e007082
Research output: Contribution to journal › Article
A Randomized Controlled Trial of Angiotensin-Converting Enzyme Inhibition for Skeletal Muscle Dysfunction in COPD
Shrikrishna, D., Tanner, R. J., Lee, J. Y., Natanek, A., Lewis, A., Murphy, P. B., Hart, N., Moxham, J., Montgomery, H. E., Kemp, P. R., Polkey, M. I. & Hopkinson, N. S. 1 Oct 2014In : Chest.146, 4, p. 932-9409 p.
Research output: Contribution to journal › Article
Neural respiratory drive (NRD) measured by parasternal electromyography predicts clinical deterioration and early readmission in patients with acute exacerbation of COPD (AECOPD)
Suh, E-S., Mandal, S., Harding, R., Ramsay, M., Kamalanathan, M., Henderson, K., Douiri, A., Rafferty, G., Murphy, P. B., Moxham, J.Hart, N.Sep 2014In : European Respiratory Journal.44
Research output: Contribution to journal › Article
Trials of home mechanical ventilation in COPD: what have we learnt?
Murphy, P. B.Hart, N.Sep 2014In : Thorax.69, 9, p. 787-7882 p.
Research output: Contribution to journal › Editorial
A cohort study to identify simple clinical tests for chronic respiratory failure in obese patients with sleep-disordered breathing
Mandal, S., Suh, E. S., Boleat, E., Asher, W., Kamalanathan, M., Lee, K., Douiri, A., Murphy, P. B., Steier, J.Hart, N.Apr 2014In : BMJ Open Respiratory Research.1, 1, p. N/A7 p., e000022
Research output: Contribution to journal › Article
Clinical predictive value of manual muscle strength testing during critical illness: an observational cohort study
Connolly, B. A., Jones, G. D., Curtis, A. A., Murphy, P. B., Douiri, A., Hopkinson, N. S., Polkey, M. I., Moxham, J.Hart, N.10 Oct 2013In : CRITICAL CARE.17, 5, 9 p., R229
Research output: Contribution to journal › Article
Authors' reply to: Noninvasive mechanical ventilation with high pressure strategy remains a "double edged sword"?
Murphy, P., Brignall, K., Moxham, J., Polkey, M. I., Davidson, A. C. & Hart, N.2013In : International journal of chronic obstructive pulmonary disease.8, p. 257-2582 p.
Research output: Contribution to journal › Letter
High pressure versus high intensity noninvasive ventilation in stable hypercapnic chronic obstructive pulmonary disease: a randomized crossover trial
Murphy, P., Brignall, K., Moxham, J., Polkey, M. I., Davidson, A. C. & Hart, N.Dec 2012In : International journal of chronic obstructive pulmonary disease.7, p. 811-8188 p.
Research output: Contribution to journal › Article
Obesity Hypoventilation Syndrome: The Need For a Multifaceted Approach to Treatment
Murphy, P. B., Polkey, M. I. & Hart, N.Aug 2012In : Chest.142, 2, p. 540-5412 p.
Research output: Contribution to journal › Letter
Volume targeted versus pressure support non-invasive ventilation in patients with super obesity and chronic respiratory failure: a randomised controlled trial
Murphy, P. B., Davidson, C., Hind, M. D., Simonds, A., Williams, A., Hopkinson, N. S., Moxham, J., Polkey, M. & Hart, N.Aug 2012In : Thorax.67, 8, p. 727-7348 p.
Research output: Contribution to journal › Article
Neural respiratory drive as a physiological biomarker to monitor change during acute exacerbations of COPD
Murphy, P. B., Kumar, A., Reilly, C., Jolley, C., Walterspacher, S., Fedele, F., Hopkinson, N. S., Man, W. D-C., Polkey, M. I., Moxham, J.Hart, N.Jul 2011In : Thorax.66, 7, p. 602-6087 p.
Research output: Contribution to journal › Article
Assessment of respiratory muscle strength in motor neurone disease: Is asking enough?
Murphy, P., Lyall, R., Hart, N. & Polkey, M. I. 1 Feb 2010In : European Respiratory Journal.35, 2, p. 245-2462 p.
Research output: Contribution to journal › Article
Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q
Curtis, D., Kalsi, G., Brynjolfsson, J., McInnis, M., O'Neill, J., Smyth, C., Moloney, E., Murphy, P., McQuillin, A., Petursson, H. & Gurling, H. Jun 2003In : Psychiatric Genetics.13, 2, p. 77-848 p.
Research output: Contribution to journal › Article
No evidence for linkage of schizophrenia to DXS7 at chromosome Xp11
Kalsi, G., Gamble, D., Curtis, D., Brynjolfsson, J., Sigmundsson, T., Butler, R., Read, T., Murphy, P., Petursson, H. & Gurling, HMD. Dec 1999In : Psychiatric Genetics.9, 4, p. 197-1993 p.
Research output: Contribution to journal › Article
New DNA markers with increased informativeness show diminished support for a chromosome 5q11-13 schizophrenia susceptibility locus and exclude linkage in two new cohorts of British and Icelandic families
Kalsi, G., Mankoo, B., Curtis, D., Sherrington, R., Melmer, G., Brynjolfsson, J., Sigmundsson, T., Read, T., Murphy, P., Petersson, H. & Gurling, H. May 1999In : Annals of Human Genetics.63, p. 235-24713 p.
Research output: Contribution to journal › Article
Tests of linkage, allelic and genotypic association between schizophrenia and the gene for the D3 dopamine receptor, DRD3
Kalsi, G., Curtis, D., Brynjolfsson, J., Sigmundsson, T., Petursson, H., Butler, R., Read, T., Murphy, P. & Gurling, HMD. 1998In : Psychiatric Genetics.8, 3, p. 187-1893 p.
Research output: Contribution to journal › Article
Exclusion of linkage between schizophrenia and the gene encoding a neutral amino acid glutamate/aspartate transporter, SLC1A5
Chen, ACH., Kalsi, G., Brynjolfsson, J., Sigmundsson, T., Curtis, D., Butler, R., Read, T., Murphy, P., Barnard, EA., Petursson, H. & Gurling, HMD. 21 Feb 1997In : American Journal of Medical Genetics.74, 1, p. 50-523 p.
Research output: Contribution to journal › Article
Two-locus admixture linkage analysis of bipolar and unipolar affective disorder supports the presence of susceptibility loci on chromosomes 11p15 and 21q22
Smyth, C., Kalsi, G., Curtis, D., Brynjolfsson, J., ONeill, J., Rifkin, L., Moloney, E., Murphy, P., Petursson, H. & Gurling, H. 1 Feb 1997In : Genomics.39, 3, p. 271-2788 p.
Research output: Contribution to journal › Article
Exclusion of linkage of schizophrenia to the gene for the glutamate GluR5 receptor
Chen, ACH., Kalsi, G., Brynjolfsson, J., Sigmundsson, T., Curtis, D., Butler, R., Read, T., Murphy, P., Petursson, H., Barnard, EA. & Gurling, HMD. 15 Jan 1997In : Biological Psychiatry.41, 2, p. 243-2453 p.
Research output: Contribution to journal › Article
Linkage analysis of manic depression (bipolar affective disorder) in Icelandic and British kindreds using markers on the short arm of chromosome 18
Kalsi, G., Smyth, C., Brynjolfsson, J., Sherrington, RS., ONeill, J., Curtis, D., Rifkin, L., Murphy, P., Petursson, H. & Gurling, HMD. 1997In : Human Heredity.47, 5, p. 268-27811 p.
Research output: Contribution to journal › Article
Lack of evidence for close linkage of the glutamate GluR6 receptor gene with schizophrenia
Chen, ACH., Kalsi, G., Brynjolfsson, J., Sigmundsson, T., Curtis, D., Butler, R., Read, T., Murphy, P., Petursson, H., Barnard, EA. & Gurling, HMD. Dec 1996In : The American Journal of Psychiatry.153, 12, p. 1634-16363 p.
Research output: Contribution to journal › Article
Erratum: Schizophrenia susceptibility and chromosome 6p24-22 (vol 11, pg 234, 1995)
Gurling, H., Kalsi, G., Chen, ACH., Green, M., Butler, R., Read, T., Murphy, P., Curtis, D. & Sharma, T.May 1996In : Nature Genetics.13, 1, p. 129-1291 p.
Research output: Contribution to journal › Article
Further tests for linkage of bipolar affective disorder to the tyrosine hydroxylase gene locus on chromosome 11p15 in a new series of multiplex British affective disorder pedigrees
Smyth, C., Kalsi, G., Brynjolfsson, J., ONeill, J., Curtis, D., Rifkin, L., Moloney, E., Murphy, P., Sherrington, R., Petursson, H. & Gurling, H. Feb 1996In : The American Journal of Psychiatry.153, 2, p. 271-2744 p.
Research output: Contribution to journal › Article
Linkage study of the D-5 dopamine receptor gene (DRD5) in multiplex Icelandic and English schizophrenia pedigrees
Kalsi, G., Sherrington, R., Mankoo, BS., Brynjolfsson, J., Sigmundsson, T., Curtis, D., Read, T., Murphy, P., Butler, R., Petursson, H. & Gurling, HMD. Jan 1996In : The American Journal of Psychiatry.153, 1, p. 107-1093 p.
Research output: Contribution to journal › Article
INVESTIGATION BY LINKAGE ANALYSIS OF THE XY PSEUDOAUTOSOMAL REGION IN THE GENETIC SUSCEPTIBILITY TO SCHIZOPHRENIA
KALSI, G., CURTIS, D., BRYNJOLFSSON, J., BUTLER, R., SHARMA, T., MURPHY, P., READ, T., PETURSSON, H. & GURLING, HMD. Sep 1995In : British Journal of Psychiatry.167, p. 390-3934 p.
Research output: Contribution to journal › Article
LINKAGE ANALYSIS OF CHROMOSOME 22Q12-13 IN A UNITED-KINGDOM ICELANDIC SAMPLE OF 23 MULTIPLEX SCHIZOPHRENIA FAMILIES
KALSI, G., BRYNJOLFSSON, J., BUTLER, R., SHERRINGTON, R., CURTIS, D., SIGMUNDSSON, T., READ, T., MURPHY, P., SHARMA, T., PETURSSON, H. & GURLING, HMD. 14 Aug 1995In : American Journal of Medical Genetics.60, 4, p. 298-3014 p.
Research output: Contribution to journal › Article
EXCLUSION OF LINKAGE OF SCHIZOPHRENIA TO THE GENE FOR THE DOPAMINE D2 RECEPTOR (DRD2) AND CHROMOSOME 11Q TRANSLOCATION SITES
KALSI, G., MANKOO, BS., CURTIS, D., BRYNJOLFSSON, J., READ, T., SHARMA, T., MURPHY, P., PETURSSON, H. & GURLING, HMD. May 1995In : Psychological Medicine.25, 3, p. 531-5377 p.
Research output: Contribution to journal › Article
LINKAGE FINDINGS IN BIPOLAR DISORDER
GURLING, H., SMYTH, C., KALSI, G., MOLONEY, E., RIFKIN, L., ONEILL, J., MURPHY, P., CURTIS, D., PETURSSON, H. & BRYNJOLFSSON, J. May 1995In : Nature Genetics.10, 1, p. 8-92 p.
Research output: Contribution to journal › Letter
GENETIC-LINKAGE ANALYSIS OF MANIC-DEPRESSION IN ICELAND
CURTIS, D., SHERRINGTON, R., BRETT, P., HOLMES, DS., KALSI, G., BRYNJOLFSSON, J., PETURSSON, H., RIFKIN, L., MURPHY, P., MOLONEY, E., MELMER, G. & GURLING, HMD. Sep 1993In : Journal of the Royal Society of Medicine.86, 9, p. 506-5105 p.
Research output: Contribution to journal › Article
The above report is produced using the following setup
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