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BANGSHIL IN G. U. T. INFECTIONS

Bangshil was tried in 110 patients of Prostatities Cystitis & Enlarged prostate, 86.3% of the patients had good relief with Bangshil treatment.

Check Panendoscopy revealed definite clearance of symptoms following a course of Bangshil -

Response in Grade 1 to Grade 11 Benign Hypertrophic Prostate (B. H. P.) with Prostatitis is quite satisfactory.

In many cases therapy with Bangshil postponed Surgery in cases where the enlargement of Prostate was even more than Grade If.

BANGSHIL* IN THE TREATMENT OF

PROSTATITIS, CYSTITIS AND ENLARGED PROSTATE

(A Clinical Study)

Professor of Surgery, A. M. Sathyanarayanan, M.S., Asst. Professor of Surgery, Govt. Stanley Hospital £t Stanley

D. Jagadisan, M.S., M.Ch. (Urology), ft Professor of Urology, & J. Shamala, M.B.B.S., House Surgeon,

Medical College, Madras 600001.

Introduction

Gt;nito-Urinary Infections and complaints are a world problem. This is more particularly so about Prostate and Bladder.

We wanted to study the drugs which would control the infection and give symptomatic relief with the least toxic or side effects. So; we used Bangshil for our study.

I3angshil

Bangshil contains Bang Bhasma (Tin Bhasma), Shilajit, Chandan (Sandalwood), Vanslochan, Loha Bhasma (Iron Bhasma), Svarna makshikam, Guggul and other drugs.

* Product of Alarsin Pharmaceuticals, Bcmbay, 400023.

Antiseptic, Vol: 75, No. 2. P. 81-94 Feb. 1978.

Bangshil formula has synergistic action. It has anti-inflammatory, antibacterial, antiseptic, astringent, diuretic, healing and cooling properties. It detoxicates genito-urinary tract and restores normal physiological functions. It is said to raise body resistance, induce muscular and nervine relaxation and to give a sense of well being.

Materials and methods

This study was conducted at the Govt. Stanley Hospital, Madras, during the years 1973-1976. The total number of cases that could be studied was 110. Most of the cases turned out to be males. As there were only a few females, they were excluded from the study.

Most of the cases had various antibiotics and urinary antiseptics many times in the past with recurrences and relapses.

Urine analysis, urine culture, Hb%, Blood Sugar, Blood Urea, V. D. R. L., Plain X-Ray K.U.B., Intravenous Urography, pH Examination and Panendoscopy were done in all the cases. Repeat investigations of urine and panendoscapy were done after two weeks of clinical trial with Bangshil to assess the results. Subjective feeling of the patient as to symptomatic relief and objective assessment by urine analysis and check panendoscopy at the end of a minimum period of two weeks of treatment with Bangshil, were taken into consideration for the final assessment. Though further treatment was given depending upon the clinical improvement of each, final assessment of results was made at the end of the minimum course of treatment of two weeks.

Age groups

The age groups were between 20-80 years. Most of the patients were aged more than 40 years. While 23.7% were aged 20-40 years those aged over 40 years formed 76.3%. The details of age group are given in Table No. 1.

TABLE No, i;

Showing Age Groups

Age Groups in Years / No. / 9'°
20-25 Yrs. / 8 / 7.3%
26-30 Yrs., / 6 / 5.5°i'o
31-35 Yrs., / 8 / 7.3%
36-40 Yrs., / 4 / 3.6%
41-45 Yrs. / 3 / 2.7%
46-50 Yrs. / 12 / 10.9%
51-55 Yrs., / 20 / 18.2%
56-60 Yrs., / 17 / 15.57,
61-65 Yrs. / 16 / 14.5%
66-70 Yrs. / 4 / 3.67,
71-75 Yrs. / 10 / 9.1%
76-80 Yrs., / 2 / 1.8%
Total / 110 / 100.0°I°

Symptoms

Generally a patient had more than one symptom. Frequency of micturition was the most commonly occurring symptom -with 87.2% having it. Next came the symptom of burning micturition with 72.7%. Difficulty in Passing Urine came next with 54.5%,. The occurrence of precipitancy, dysuria etc. including the age groups of symptoms are all shown in detail in Table No. 2.

TABLE No. 2:

Showing Symptoms and their relation to Age Groups. (N.=110)

20-30
Yrs. / 31-40
Yrs. / 41-50
Yrs. / 51-60
Yrs. / 61-70
Yrs. / 71-80
Yrs. / Total / %
1. Frequency of
micturition : / 10 / 12 / 15 / 27 / 20 / 92 / 96 / 87.2
2. Burning of
micturition : / 8 / 12 / 15 / 14 / 20 / 11 / 80 / 72.7
3. Difficulty in
Passing Urine : / 2 / 3 / 6 / 25 / 12 / 12 / 60 / 54.5
4. Precipitancy : / 4 / 5 / 3 / 21 / 11 / 12 / 56 / 50.9
5. Dysuria : / 13 / 12 / 9 / 5 / 3 / 4 / 46 / 41.8
6. Dribbling of
Urine : / 0 / 1 / 2 / 9 / 6 / 12 / 30 / 27.3
7. Haematuria : / 8 / 2 / 3 / 1 / 2 / 0 / 7 6 / 14.5
8. Weak or loss
of erection : / 0 / 4 / 1 / 0 / 0 / 0 / 5 / 4.5
No. of cases
in Age Groups: / 14 / 12 / 15 / 37 / 20 / 12 / 110

Other associated diseases confirmed by inve9tigations.

There were 15 cases of diabetes, 6 cases of Pulmonary Tuberculosis, 10 cases of anaemia and 6 cases of vescical stones. All these were given appropriate treatment. There was no case of malignancy.

Details of diagnosis

There were 66 cases of Enlarged Prostate (60%), 28 cases of Prostatitis (25.5%) and 16 cases of Cystitis (14.5%). The details of these conditions, including the age are given in table No. 3.

TABLE No. 3:

Showing the conditions with Age Groups.

20-30
Yrs. / 31-40
Yrs. / 41-50
Yrs. / 51-60
Yrs. / 61-70
Yrs. / 71-80
Yrs. / Total
Enlarged Prostate : / - / - / 12 / 32 / 14 / 8 / 66 / 60.0%
Prostatitis : / - / 10 / 3 / 5 / 6 / 4 / 28 / 25.5%
Cystitis : / 14 / 2 / - / - / - / - / 16 / 14.5%
Total : / 14 / 12 / 15 / 37 / 20 / 12 / 110 / 100.070

Dosage of Bangshil

Bangshil was given 2 tablets, three times a day for a minimum period o1 2 weeks initially and further treatment depended upon the clinical improvement.

Final results

Assessment was made at the end of the minimum period of two week:;' treatment with Bangshil. Assessment was made an` the basis of subjective feeling of the patient as to symptomatic relief and objective assessment by Urine Analysis and Check Panendoscopy.

There was Total Relief in 70 cases (63.6%.), Partial Relief in 25 cases (22.7%), and there was No Relief in l:i cases (13.7%,). The details of assessment of results in Enlarged Prostate, Prostatitia and Cystitis are given in detail in Table No. 4.

TABLE No. 4: Results:

Relief / Enlarged
Prostate / Prostatitis / Cystitis / Total / o
Total Relief : / 36 / 20 / 14 / 70 / 63.6%
Partial Relief : / 18 / 5 / 2 / 25 / 22.7%
No. Relief : / 12 / 3 / - / 15 / 13.7%
Total : / 66 / 28 / 16 / 110 / 100.0%

Comparative assessment of results

Among the cases of Enlarged Prostate, there was Total Relief in 54.5%.. Among the cases of Prostatitis, l.lvere was Total Relief in 71.4%. Among the cases of Cystitis, there was Total Relief in 87.5%,. The details are given in Table 5.

TABLE No. 5: Showing assessment of results.

No. of
Cases / Complete
Relief / % / Partial
Relief / % / Relief
No / %
Enlarged Prostate : / 66 / 36 / (54.5%) / 18 / (27.3%) / 12 / (18.2%)
Prostatitis : / 28 / 20 / (71.4%) / 5 / (17.9%) / 3 / (10.7%)
Cystitis : / 16 / 14 / (87.5%) / 2 / (12.5%) / - / -
Total / 110 / 70 / 25 / 15
100% / 63.6% / 22.7% / 13.7%

Check Panendoscopy revealed definite clearance of symptoms following two weeks of Bangshil treatment in those cases where complete relief was seen. Re:ponse in Grade I and Grade II of Enlarged Prostate was quite satisfactory. In those cases where the enlargement of Prostate was even more than Grade II, therapy with Bangshil postponed Surgery. This was noteworthy in this clinical trial with Bangshil. The use of Bangshil will be of great help, particularly in those cases where surgery is contraindicated.

Toxic & Side Effects

There was no evidence of any adverse or side effects in any of our patients who received the drug even for a prolonged period.

Summary:

Following were the observations of our study on Bangshil (Alarsin) in Prostatitis.

(i) Common Age Group 50-r0 Yrs.

(ii) Common symptoms-Frequency/Burning Micturition.

(iii) No definite relationship between symptoms and age except Dysuria/Frequency Syndrome was more frequent after 50 years when associated B.H.P. (Benign Hypertrophic Prostate) is Common.

(iv) Check Panendoscopy revealed definite clearance of Symptoms following a course of Bangshil (Alarsin) in those cases where complete relief was achieved.

(v) Response in Grade I to Grade II B.H.P. (Benign Hypertrophic Prostate) with Prostatitis is quite satisfactory.

(vi) Dose of Bangshil : Two tablets thrice a day for initial period of 2 weeks and later continued depending upon the symptoms.

(vii) There was no evidence of side effects in any case of our patients who were receiving the Drug for prolonged period.

(viii) In many cases therapy with Bangshil postponed Surgery in cases where the enlargement of Prostate was even more than Grade II.

Conclusion

This study has shown that Hangshil has a definite role in the treatment of Enlarged Prostate, Prostatitis and Cystitis 70 cases (63.6%) showed Complete Relief, 25 cases (22.7r") showed Partial Relief and 15 cases (13.7%) showed No Relief. No untoward side effects were observed with Bangshil therapy even in

cases which were advised to take it for a long duration. Those who showed Partial Relief were generally those cases who had Associated Diseases like Diabetes, minor Grade I to Grade II prostatic enlargement, urenthral strictures and calcium diseases of the bladder. Those cases which showed No Relief had huge enlargement of prostate (Grade II to Grade III) which required surgery. It is worth mentioning that there were cases where they presented with dribbling and impending fear of surgery. When they were put on t3angshil treatment for 10 days, the symptoms were relieved completely and they were symptoms free for more than two years.

Acknowledgement

Our thanks to Superintendent & Principal, Stanley Hospital and Stanley Medical College, Madras, who permitted us to make use of the Hospital patients and records for this study.

We are highly grateful to the patients for their kind cooperation during the trial and during follow-up studies.

Our thanks to Alarsin Pharmaceuticals, Bombay 400023, for their cooperation.

References

1. Bapat, S.S. (1975): "Double Blind Crossover-Recheck Study on Bangshil: Paper read at XXI Annual Conference of International College of Surgeons, Gulbarga (Indian Section) : 5-? Oct. 1975.

2. Agarwal, R. S.: (1975): Burning Micturition: Rajasthan Med. J.: XIV:1:19r5.