ADDENDUM 1

DATE: January 8, 2016

PROJECT: Intra-Arterial Vasospasm Trial Redesign

RFP NO: 744-R1608

OWNER: The University of Texas Health Science Center at Houston

TO: Prospective Proposers

This Addendum forms part of and modifies Proposal Documents dated, (Date Bid Posted), with amendments and additions noted below.

1. Scope of Work, Section 5.4, Objective 1

Omit this section. This work is already complete

2. Please see revised Pricing and Delivery Schedule, Section 6 on the following page. Proposer should include this revised copy with their proposal instead of the original RFP version.

SECTION 6

PRICING AND DELIVERY SCHEDULE - REVISED

Proposal of:______

(Proposer Company Name)

To: The University of Texas Health Science Center at Houston

Ref.: Services related to the Intra-Arterial Vasospasm Trial Redesign

RFP No.:744-R1608

Ladies and Gentlemen:

Having carefully examined all the specifications and requirements of this RFP and any attachments thereto, the undersigned proposes to furnish the services required pursuant to the above-referenced Request for Proposal upon the terms quoted below.

6.1 Pricing for Services Offered

Payment 1 – Completion of first DSMB meeting report $______

Payment 2 – End of Interim Analysis (approx. 12-18 months after beginning of enrollment)

$______

Payment 3 – End of Complete Enrollment (approx. 24-30 months after beginning of enrollment)

$______

Payment 4 – Study Completion $______

Reimbursable Expenses $______

Grand Total $______

6.2 Delivery Schedule of Events and Time Periods

______Calendar Days to begin work after receipt of purchase order

6.3 University’s Payment Terms

University’s standard payment terms for services are “Net 30 days.” Proposer agrees that University will be entitled to withhold ______percent (______%) of the total payment due under the Agreement until after University’s acceptance of the final work product. Indicate below the prompt payment discount that Proposer will provide to University:

Prompt Payment Discount: _____%_____days/net 30 days.

Respectfully submitted,

Proposer: ______

By:______

(Authorized Signature for Proposer)

Name:______

Title:______

Date:______