Table S3: Number of Repeat Elements in the Chimpanzee Genome in Regions Flanking the Inversion

Supplementary Table 4: Number of SINE/LINE elements in the chimpanzee genome sequence flanking the sites of the 24 human-specific inversion breakpoints

Inversion
# / Number of observed repeat elements / Length of the regions investigated (bp)
Alu / MIR / LTR / L1 / L2
1 / 2 / 0 / 0 / 0 / 0 / 1358
3 / 0 / 0 / 0 / 0 / 1 / 1442
4 / 0 / 1 / 0 / 0 / 0 / 1417
6 / 0 / 0 / 0 / 2 / 0 / 1534
7 / 1 / 0 / 0 / 0 / 0 / 1608
10 / 3 / 0 / 0 / 0 / 0 / 2000
11 / 0 / 0 / 0 / 1 / 0 / 2219
13 / 0 / 0 / 0 / 1 / 0 / 2000
14 / 0 / 0 / 0 / 0 / 0 / 2000
15 / 0 / 1 / 1 / 0 / 0 / 2761
19 / 0 / 0 / 0 / 1 / 0 / 2274
23 / 1 / 1 / 2 / 0 / 0 / 2000
24 / 0 / 0 / 1 / 2 / 0 / 2526
25 / 0 / 1 / 0 / 3 / 0 / 1843
26 / 0 / 1 / 1 / 0 / 1 / 2000
27 / 0 / 0 / 0 / 0 / 1 / 1179
28 / 0 / 1 / 2 / 0 / 0 / 3125
29 / 0 / 0 / 0 / 0 / 0 / 1377
30 / 0 / 0 / 1 / 4 / 0 / 2928
31 / 0 / 1 / 1 / 2 / 0 / 2414
32 / 4 / 1 / 0 / 0 / 0 / 1578
33 / 0 / 0 / 1 / 0 / 0 / 2586
34 / 0 / 1 / 5 / 2 / 0 / 2380
35 / 0 / 0 / 1 / 0 / 0 / 2000
Total number of bp analysed / 48549
Total number of observed repeats / 11 / 9 / 16 / 18 / 3
Expected number of repeatsa / 18.4 / 9.2 / 7.5 / 9.3 / 5.2
P-valueb / 0.07 / 1 / 0.0067 / 0.01 / 0.34

a: The expected number of repeat elements was calculated by dividing the total number of repeat elements in the human and chimpanzee genomes by the length in bp of the respective genomes (as summarized in Supplementary Table 7) and multiplying by the length of the inversion-flanking regions analysed (in bp).

b: as determined by the test for observed versus expected rates of occurrence of repeats based on the Poisson distribution.

MIR: mammalian-wide interspersed repeats; LTR: Long Terminal Repeat retrotransposons