The Heller School for Social Policy and Management, Brandeis University

International Program on Health Policy and Management, Master of Science

HS 402f.Research Methods

Spring 2018 (Module 2)

Tuesday, 2:00 – 4:50 pm

Instructors:Diana Bowser, Sc.D. M.P.H.

Phone:(781) 736-4811

Office:Heller 272

E-mail:

MoavenRazavi, PhD

Phone: (781) 736-8679

Email:

University Notices

1. If you are a student with a documented disability on record at Brandeis University and wish to have a reasonable accommodation made for you in this class, please see me immediately.

2. You are expected to be honest in all of your academic work.The University policy on academic honesty is distributed annually as section 5 of the Rights and ResponsibilitiesHandbook. Instances of alleged dishonesty are subject to possible judicial action.Potential sanctions include failure in the course and suspension from the University.If you have any questions about my expectations, please ask.

Academic integrity is central to the mission of educational excellence at Brandeis University.Each student is expected to turn in work completed independently, except when assignments specifically authorize collaborative effort. It is not acceptable to use the words or ideas of another person – be it a world-class philosopher or your roommate – without proper acknowledgement of that source.This means that you must use footnotes and quotation marks to indicate the source of any phrases, sentences, paragraphs or ideas found in published volumes, on the internet, or created by another student.If you are in doubt about the instructions for any assignment in this course, you must ask for clarification.

Course Requirements

  1. Attendance at all sessions; prompt arrival.
  2. Preparation of all readings.
  3. Participation in class discussions and any small group work.
  4. Timely submission/presentation of assignments.
  5. Completion of 2 writing assignments, a final paper,and group presentations.
  6. Participation in class discussion.
  7. Contribution to requirements and objectives of group work.
  8. Being helpful and considerate to other students.

This is a module course of the MS/GHPM program.This course is also open to students in other programs who are interested in the topic.

This syllabus is subject to change at any time at the discretion of the instructors.When in doubt, please ask the instructors.

Course Description

The purpose of this course is to prepare students (1) to understand the fundamentals of the rigorous conduct of health policy research methods and (2) to be sophisticated consumers of empirical health policy research. A variety of class formats will be used throughout the semester including lectures, discussions, and seminars, depending upon the topic and readings. Every student is expected to come to each class prepared to raise questions from the readings, respond to questions raised by other students and the instructor, discuss issues, and point out implications of the readings for policy and planning research.

Course Reading

The primary text for this course is Shadish, W.R., Cook, T.D., & Campbell, D.T. (2002). Experimental and quasi-experimental designs. Boston: Houghton-Mifflin Co. Additional papers and reports are indicated for each unit of the class. These will be available online or on Latte.

Other important readings are specified under the various lecture topics. Reading extensively from the professional literature on health system performance is very important for this course. Students are expected to do these readings, and to be able to summarize what they have read when called upon to do so in class.

Student Evaluation

Research Proposal35%

Final paper45%

Class participation20%

Course Outline Sessions & Assignments

Date / Session / Topic / Instructor
March 13 / 1 / Topic 1 Course overview
Topic 2 Presentation of research methods, discussion of motivation for research, cause and effect, hypotheses, and Internal and External Validity / Razavi
March 20 / 2 / Sample and sample size / Bowser
March 27 / 3 / Randomized Controlled Trials (RCT)
Case Study: An RCT to investigate a quality of care intervention in surgical ICU / Bowser
April 10 / 4 / Observational Studies (case control, cohort, pre-post policy change) / Bowser
April 17 / 5 / Quasi Experimental Designs and Difference-in-Differences Designs / Razavi
April 24 / 6 / Topic 1: Alternative Quasi Experimental Designs: Interrupted Time Series and Regression Discontinuity Designs
Topic 2: Matching: Background characteristics based matching and Propensity Score Matching / Razavi
May 1 / 7 / Topic 1: Generalized Inference: Multistudy programs, Systematic Reviews and Meta Analysis
Topic 2: Mixed-Method Quantitative-Qualitative Evaluation Designs
Topic 3: An overview of alternative designs for dynamic and complex systems: static and dynamic microsimulations, complex system modeling, Case Study: PRISM / Razavi

WritingAssignments

Students will complete several short writing assignments and/or other short assignmentsand post them on LATTE (2-3 pages, 12 font, 1.5 spacing). The purpose of these papers is to summarize your thoughts on a topic that is central to the assigned readings for that class or the previous class.

Group Presentations

Students will be expected to work in a group and lead a group presentation for one hour during the second half of one class on the topic of that class. Additional details will be given regarding the presentation (style, content, etc. during the first class).

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Class Schedule and Topics

(Preliminary and subject to change)

March13 (Tuesday First Class)

Class 1: Course overview (Topic 1); Presentation of research methods, discussion of motivation for research, cause and effect, hypotheses testing

(Topic 2): Internal and External Validity

Shadish, Cook & Campbell, chapters 1 (pages 1-12), 2 & 3

Lui, Li et al. (2015). Global, regional, and national causes of child mortality in2000–13, with projections to inform post-2015 priorities:an updated systematic analysis.Lancet.385(9966): 430-440 (Introduction and Methods Only)

March 20

Class 2

Topic 1: Review Internal and External Validity

Topic 2: Sample, Sample Size

Shadish, Cook & Campbell, chapters 8-10

March 27

Class 3:Randomized Control Trials

Shadish, Cook & Campbell, chapters 4 & 5 (sections of these chapters)

Case Study: Luca M. Bigatello, H.A., A. K. H., B. N., J. D. R., K. A., A. C., U. S., MoavenRazavi. "Effects of routine monitoring of delirium in a surgical / trauma intensive care unit."Journal of Trauma and Acute Care Surgery 74. 3 (2013): 876–883.

April10

Class 4:Observational Studies

Assignment 1– Developing a research protocol with a RCT design

Shadish, Cook & Campbell, chapter 6

Levine, R.S., Rust, G.S., Pisu, M., Agboto, V., Baltrus, P.A., Briggs, N.C., et al. (2010).Increased Black-white disparities in mortality after the introduction of lifesaving innovations: A possible consequence of US federal laws.American Journal of Public Health, 100, 2176-2184.

Additional reference to be added

April 17

Class5: Quasi Experimental Designs and Difference-in-Differences Designs

Shadish, Cook & Campbell, chapter 5

MoavenRazavi (2011). Impact of Structural Adjustment Programs on Healthcare Financing in Iran.Chapter 3 and Chapter 4

Grace et al. (2012).Effect of Nonpayment for Preventable Infections in U.S. Hospitals.New England Journal of Medicine. 367:1428-1437

Additional reference to be added

April 24

Class 6:

Assignment 3– Adapting your research question to a new study design

This paper as I will explain in details is to demonstrate your ability to propose a quasi-experimental design when experimentation is not an option which applies to most of the real world policies. In session 5, I will lecture the subject and then you have the session 6 to ask calcifying questions before you submit your paper on the Friday of that week by midnight to give me the weekend to grade them.

Directions:

We will discuss in my first session that in absence of a control group how unreliable and biased the results and impact estimates of the observational studies could be. The risk of relying on sub-standard observational studies for program and policy impact evaluation reemphasizes the importance of Quasi-Experimental Designs in the evaluation research.

So your class assignment is an opportunity to apply your research methods skills to an observational retrospective dataset of your choice and try to enhance it to a Quasi-Experimental Design in order to estimate the impact of a program/policy/intervention/reform etc. You then propose your regression model that follows the standard construct of Difference-in-Differences using proper arrangement and interaction terms created according to your pre/post and intervention/pseudo control groups.

Your paper outline should look like the following:

1) Research question: Cause and effect relationship that will generate your null hypothesis

2) Data section: Your dataset is explained here

3) Method: you explain how you pick your pseudo control group and then construct your regression model

4) Conclusion/Discussion using hypothetical estimates for your regression.

Note that I do NOT expect you to apply a regression model to the data, rather you explain how you conduct your model once the real data are given to you, then make some assumptions about the sign and size of your regression coefficient estimates and interpret the findings.

An example of such paper from previous year is made available on LATTE thanks to the permission of the former Heller graduate RoshanKarn (MS-2016).

This course ends shortly prior to your graduation and final grade submission date so please keep your paper short and no longer that 10 double space pages so I will have enough time to evaluate your work.

Topic I: Alternative Quasi Experimental Designs: Interrupted Time Series and Regression Discontinuity Designs

Topic II: Matching: Background characteristics based matching and Propensity Score Matching

Shadish, Cook & Campbell, chapters6 and 7

Ralph B. Doagostino. 1998. Tutorial in Biostatistics:Propensity Score Methods for Bias Reduction in the Comparison of Treatment to a Non-Randomized Control Group. Statistics in Medicine. 17, 2265-2281

Keisuke Hirano. (2001) Estimation of Causal Effects using Propensity Score Weighting: An Application to Data on Right Heart Catheterization. Health Services Outcome and Research Methodology.eH

2:259-278

Additional reference to be added

May 1st

Class 7:

Topic I: Generalized Inference: Multistudy programs, Systematic Reviews and Meta Analysis

Topic II: Mixed-Method Quantitative-Qualitative Evaluation Designs

Shadish, Cook & Campbell, chapter 13

Andy P. Field1 and Raphael Gillett (2010).How to do a meta-analysis.British Journal of Mathematical and Statistical Psychology.Volume 63, Issue 3, 665–694

John W. Creswall (2003). Research Design: Qualitative, Quantitative and Mixed Methods Approaches, Second Edition. SAGE Publications.

Additional reference to be added

1