Table e-2. Associations of Midlife and Late Life Cognitive Activities and Exercise With Mild Cognitive Impairment
Midlife / Late Life
No. at Risk/ Events / HR
(95% CI) / P Value / No. at Risk/ Events / HR
(95% CI) / P Value
Artistic activities
No / 185/91 / 1.0 (reference) / 204/99 / 1.0 (reference)
Yes / 41/13 / 0.56
(0.31, 1.00) / 0.05 / 22/5 / 0.37
(0.15, 0.92) / 0.03
Craft activities
No / 91/44 / 1.0 (reference) / 141/72 / 1.0 (reference)
Yes / 135/60 / 0.72
(0.47, 1.10) / 0.13 / 85/32 / 0.57
(0.37, 0.87) / 0.009
Social activities
No / 41/24 / 1.0 (reference) / 75/37 / 1.0 (reference)
Yes / 185/80 / 0.45
(0.27, 0.74) / 0.002 / 151/67 / 0.74
(0.49, 1.12) / 0.15
Group activities
No / 112/57 / 1.0 (reference) / 128/58 / 1.0 (reference)
Yes / 114/47 / 0.61
(0.41, 0.91) / 0.02 / 98/46 / 0.98
(0.66, 1.45) / 0.91
Computer use
No / 190/87 / 1.0 (reference) / 148/74 / 1.0 (reference)
Yes / 36/17 / 1.16
(0.68, 2.00) / 0.58 / 78/30 / 0.60
(0.39, 0.94) / 0.03
Playing music
No / 173/82 / 1.0 (reference) / 197/94 / 1.0 (reference)
Yes / 53/22 / 1.02
(0.63, 1.66) / 0.93 / 29/10 / 0.83
(0.43, 1.61) / 0.59
Playing games
No / 47/22 / 1.0 (reference) / 63/30 / 1.0 (reference)
Yes / 179/82 / 0.86
(0.53, 1.38) / 0.52 / 163/74 / 0.74
(0.48, 1.15) / 0.18
Reading books
No / 61/28 / 1.0 (reference) / 80/40 / 1.0 (reference)
Yes / 165/76 / 0.90
(0.57, 1.43) / 0.66 / 146/64 / 0.72
(0.48, 1.09) / 0.12
Reading magazines
No / 22/12 / 1.0 (reference) / 46/22 / 1.0 (reference)
Yes / 204/92 / 0.66
(0.35, 1.25) / 0.20 / 180/82 / 0.77
(0.47, 1.25) / 0.29
Reading newspaper
No / 9/6 / 1.0 (reference) / 14/7 / 1.0 (reference)
Yes / 217/98 / 0.29
(0.13, 0.69) / 0.005 / 212/97 / 0.62
(0.29, 1.35) / 0.23
Moderate exercise (times/wk)
No, <3-4 / 122/57 / 1.0 (reference) / 155/72 / 1.0 (reference)
Yes, ³3-4 / 104/47 / 1.05
(0.71, 1.56) / 0.80 / 71/32 / 0.87
(0.57, 1.32) / 0.51

Abbreviations: HR, hazard ratio.