Rajiv Gandhi University of Health Sciences
Karnataka, Bangalore.
Proforma for Registration of Subject for Dissertation in M.D (Ayurveda).
RELEVANCE OF MOOTRA PAREEKSHA IN PRAMEHA ROGI
By
Dr. Benoy Bhaskaran
1st year M.D (Ay) Scholar,
Department of P.G. Studies in Ayurveda Sidhantha,
Alva’s Ayurveda Medical College, Moodbidri
Guide
Dr. Raghavendra Udupa. M.D (Ay)
Asst. Prof: Dept of P.G. Studies in Ayurveda Sidhantha,
Alva’s Ayurveda Medical College, Moodbidri
Co – Guide
Dr. J. Ganapathi Bhat. M.D (Ay)
Prof: Dept of P.G. Studies in Ayurveda Sidhantha,
Alva’s Ayurveda Medical College, Moodbidri
2008-2009
Alva’s Ayurveda Medical College,
Moodbidri.
From,
Dr. Benoy Bhaskaran
1st year M.D (Ay) Scholar,
Dept. of P.G Studies in Ayurveda Sidhantha,
Alva’s Ayurveda Medical College, Moodbidri.
To,
Registrar,
Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore.
Through,
The Principal and
Head of the Dept of Ayurveda Sidhantha,
Alva’s Ayurveda Medical College - Moodbidri.
Sub- Submission of Proforma for Registration of Synopsis for dissertation
work in M. D (Ay).
Respected Sir,
I request you to register the below mentioned subject in my name for submission of dissertation to Rajiv Gandhi University of Health Sciences, Bangalore as the partial fulfillment for the award of the degree M.D (Ay) in Ayurveda Sidhantha.
Title of Dissertation
RELEVANCE OF MOOTRA PAREEKSHA IN PRAMEHA ROGI
Here with I am enclosing the completed proforma for registration of Dissertation subject.
Thanking you,
Yours faithfully,
Place: Moodbidri
Date: 26/11/2008 (Dr. Benoy Bhaskaran)
Rajiv Gandhi University of Health Sciences
Karnataka, Bangalore.
ANNEXURE II
Proforma for Registration of Subject for Dissertation in M.D.
1. Name of the Candidate : DR. BENOY BHASKARAN
Address (In block letters) : 1ST YEAR, M.D. SCHOLAR,
DEPT OF P.G. STUDIES IN
AYURVEDA SIDHANTHA,
ALVA’SAYURVEDA MEDICAL
COLLEGE, MOODBIDRI.
Permanent Address : S/o Dr. M. V. Bhaskaran
Mudhayekara House
Mathirapilly,
M. A. College P.O.,
Kothamangalam,
Ernakulam Dist.
Pin-686666
2. Name of the Institution : Alva’s Ayurveda Medical
College,
Moodbidri - 574227.
3. Course of study & Subject : M.D (Ay) in Ayurveda
Sidhantha
4. Date of Admission for course : 30/07/2008
5. Title of the Topic : RELEVANCE OF MOOTRA
PAREEKSHA IN PRAMEHA ROGI
6. Brief Resume of the Intended Work
6.1 Need for the study:
Prameha roga is mentioned as one among the Mahagadas in our classical text books like Charaka Samhitha and Sushrutha Samhitha. In all Prameha the Tridosha’s are invariably involved, hence while explaining Sankhya samprapthi of Prameha, it is said that, there are 20 types of Prameha roga produced due to the vitiation of tridosha’s. It is also a disease where there is involvement of many body tissues. According to the Ayurvedic Classics, the pathogenesis of Prameha is having the involvement of Kleda (liquidity), Mamsa (muscle tissue), Meda (fatty tissue), Raktha (blood), Vasa (adipose tissue), Majja (bone marrow), Sukra (substance related to procreation), Lasika (lymph tissue), Rasa dhatu and Ojus.
The numbers of cases of diabetes in India in 2002 was: 31.7 million.
The estimated number of diabetes cases in India for 2030 will be: 79.4 million (estimate by American Diabetes Association, April 2004). People living in Indian metros suffering from diabetes are 12 %. Hence the present study is taken to study Diabetes Mellitus as per Ayurvedic perspective.
While explaining the diagnosis of Prameha, it is said that, increased frequency of micturition and turbidity of the urine are the common characteristic features of the 20 types of Prameha. The specific features of Vataja, Pittaja and Kaphaja Prameha, based on colour, taste, touch and smell according to the dosha predominance in urine are explained in Charaka Samhitha Chikitsa Sthana.
Ayurvedic classics have given importance for the physical examination of urine for the diagnosis of Prameha. Moreover the management of Prameha is also explained on the basis of predominant dosha. This aspect is taken as base for the present study. i.e., the predominant dosha of prameha will be assessed based on the physical characters of urine of the pramehi.
6.2 Review of Literature:
Ø All the Classical and contemporary information including the web site, mentioning the disease along with the proposed clinical study will be thoroughly reviewed.
Ø Review on various aspects of Prameha mentioned in the classics.
Ø Mootrapareeksha mentioned in Yogaratnakara.
Previous Work Done
Ø Mootravaha srothasa evam uske Vikaron mein sapeksha Roga Nirnaya. Dr. Roal K. H. (J.M.) – 1964
Ø Ayurveda mein Vikriti vigyana ka svaroopa (Mootra pareekshantargata). Dr. Gohil M. N.(J.M.) – 1978
Ø Studies on the concept of Dosha – Dooshya samyoga Vaishistya w.s.r. to Mootrapareeksha in Prameha roga. Dr. Baghel A. S.(J.M.) – 1994
6.3 Objective of the study.
Ø To identify prameha as per Classical reference from Sushrutha Samhitha, Nidana sthana.
Ø Physical examination of urine of the patients who have diagnosed as per Ayurvedic description.
Ø To analyze different types of Prameha based on findings of observational study.
Ø Analyzing the Upadravas according to doshas in prameha.
6.4 Hypothesis.
1. H0: - Mootra pareeksha has no role in diagnosis of Prameha roga.
2. HA - Mootra pareeksha has specific role in diagnosis of Prameha roga.
7. Materials & Methods:
7.1 Source of the Data
Ø Literary source: All classical literature and latest information center like websites will be reviewed.
Ø A minimum on 30 patients will be selected from Alva’s Ayurveda Medical College Hospital O.P., Moodbidri and other referrals fulfilling the inclusion criteria.
7.2 Method of Collection of the Data
An observational study with minimum 30 patients between the age group of 20 to 60 years, fulfilling the inclusion criteria will be selected and assigned into one group.
Diagnostic Criteria
The criteria of diagnosis will be based on the explanations of Sushrutha Samhitha Nidanasthana for the diagnosis of Prameha.
1. Increased frequency of Urination.
2. Burning sensation of the Palms and Soles.
3. Oiliness of Body.
4. Stickiness of body.
5. Heaviness of body.
6. Whitish coloured Urine.
7. Sweetness of urine.
8. Drowsiness (Tandra).
9. Body aches / Body discomforts.
10. Increased Thirst.
11. Foul smell of Breath.
12. Matting of Hairs.
13. Increased growth of Nails and Hair.
14. Accumulation of excess waste on Palate, Throat, Tongue and Teeth.
As per Acharya Susrutha, “The patient should be declared as a patient of prameha in whom all or half of the prodromal symptoms are present with excessive urination”1.
Inclusion Criteria
1. Patients within the age group of 20-60 years.
2. Patients irrespective of sex, religion and socio-economic status will be taken.
3. Patients having increased frequency of urination along with 50% of the
prodromal signs, mentioned by Acharya Susrutha.
Exclusion Criteria
1. Patients less than 20 yrs and above 60 yrs.
2. Pregnant women.
3. Patients suffering from other systemic diseases.
4. Patients diagnosed with Diabetes having, :-
5. Congenital physiological anomalies, Surgical interventions, Any traumas and those who are Insulin dependent.
Subjective Criteria
1. Karapadadaha :
0 - No Daha Present
1 - Pada or Karataladaha incontinuous.
2 - Pada or Karataladaha continuous but not severe.
3 - Pada or Karataladaha continuous and severe.
2. Heaviness:
0 - Heaviness of body not felt.
1 - Heaviness of one part of body.
2 - Heaviness of 2 parts of the body.
3 - Heaviness of half part of the body
4 - Heaviness of whole body.
3. Alasya :
0 - No Alasya.
1 - Doing satisfactory work / late initiation.
2 - Doing unsatisfactory work / late initiation.
3 - Do not want to do work / no initiation.
4. Shoola :
0 - No pain at all.
1 - Mild pain in feet or Body ache.
2 - Pain in leg-calf muscles intermittently.
3 - Pain in leg / Body ache continuously.
Objective Criteria
1. Quantity
0 - 1.5 to 2.5 lit / day.
1 - 2.5 to 3.0 lit / day.
2 - 3 to 3.5 lit / day.
3 - 3.5 and onwards lit / day.
2. Frequency :
0 - 3 to 5 times / day, rarely at night.
1 - 5 to 7 times / day, 1-2 times at night.
2 - 7 to 10 times / day,3-4 times at night.
3 - 10 to 12 times / day, 3-4 times at night.
3. Pipasa: Quantity of water intake.
0 - 1.5 to 2.5 lit / day (24 hrs)
1 - 2.5 to 3.0 lit / day
2 - 3 to 3.5 lit / day
3- 3.5 lit and more
4. Mutra Madhurya:
0 - Absence of glucose in urine.
1 - <0.05 % glucose in urine.
2 - 0.5% to 1% glucose in urine.
3 - 1% to 2% glucose in urine.
4 - >2% glucose in urine.
5. Avila Mutrata :
0 - Crystal clear fluid.
1 - Faintly cloudy or smoky slight turbidity.
2 - Turbidity clearly present (Newsprint easily read through tube)
3 - Turbidity more, Newsprint not easily read
4 - Turbidity more, Newsprint cannot read.
Study Duration
Study will be carried out for 3 to 5 days to obtain sufficient observation in each patient.
7.3 Does the study require any Investigation and interventions to be conducted on patients or other humans or animals? If so, please describe briefly:
The study will be conducted clinically. No animal experimentation is carried out.
Laboratory Investigation
Random Blood sugar.
Routine Urine investigation.
Any other investigations if necessary.
7.4 Has ethical clearance been obtained from your institution in case of 7.3?
Yes, clearance has been obtained through the ethical committee formulated in institution.
8. List of Reference
1. Sushrutha acharya, Vaidya Yadavji Trikamji acharya, Dalhanacharya, Gayadasa. Sushrutha samhitha: Nidanastana. Nibandhasangraha, Nyayachandrika Panchika: 8th ed. Varanasi: Chaukambha orientalia; p. 289-294, Sloka No. 5, 22, 23.
2. Agnivesha acharya, Vaidya Yadavji Trikamji acharya, Charaka, Dridhabala, Chakrapanidutta. Charaka samhitha: Ayurveda – Deepika. Nidanastana. Reprint 2004. Varanasi: Chaukhambha Sanskrit Sansthan; p. 211-216. Sloka 29.
3. Vagbhata acharya, Bhisagacharya Hari Shastri Paradakara Vaidya, Arunadatta, Hemadri, Anna Moreawara Kunte, Krishna Ram Chandra Shastri Navare. Astanga Hridayam: Nidanastana: Sarvangasundari, Ayurveda Rasayana. 9th ed. Varanasi: Chaukhambha Orientalia; 2002. p. 502-506.
4. Vriddha Vagbhata acharya, Shiv Prasad Sharma. Indu. Astanga samgraha: Nidanastana. Sasilekha. Varanasi: Chaukhambha Sanskrit Series Office; 2006. p. 391-395.
5. Vaidya Indradev tripati, Dayashankar tripati. Yogaratnakara, Vaidya Prabha: 2nd ed. Varanasi: Krishnadas Academy; 2007. p. 9-11.
9. Signature of Candidate :
10. Remarks of Guide :
11. Name & Designation of
11. 1 Guide : Dr. Raghavendra Udupa. M.D (Ay)
Asst. Prof. Dept of P.G. Studies,
Ayurveda Sidhantha,
Alva’s Ayurveda medical College,
Moodbidri.
11.2 Signature and seal :
11.3 Co-guide : Dr. J. Ganapathy Bhat M. D. (Ay)
Professor,
Dept. of P.G. Studies Ayurveda Sidhantha,
Alva’s Ayurveda Medical College,
Moodbidri.
11.4 Signature and seal :
11.5 Head of the Department : Dr. M. K. Sasidharan M. D. (Ay)
Prof: and Head Of the Department,
Dept. of P.G. Studies, Ayurveda Sidhantha
Alva’s Ayurveda Medical College,
Moodbidri.
11.5 Signature and seal :
12.1 Remarks of the Principal :
12. 2 Signature and seal :