CURRICULUM VITAE
Full name: Daniel Robert Lloyd
Date of birth: 3rd February 1973
Nationality: British
Address (work): Research School of Biosciences
University of Kent
Canterbury
Kent
CT2 7NJ
Tel: +44 1227 827357
Fax: +44 1227 763912
Website: www.kent.ac.uk/bio/lloyd/
Email:
Education and employment
August 2001
- present
August 1998
– July 2001
October 1994
– June 1998
October 1991
– June 1994
/University of Kent
School of Biosciences, Canterbury, Kent, CT2 7NJ
Lecturer in Pharmacology (Senior Lecturer from October 2007)Stanford University
Department of Biological Sciences, Stanford, California, USAPostdoctoral Fellow in the laboratory of Professor P. C. Hanawalt
Institute of Cancer Research
Section of Molecular Carcinogenesis, Sutton, Surrey, UKGraduate student in the laboratory of Professor D. H. Phillips
Ph.D. (Biochemistry), University of London, June 1998
University of York
Department of Chemistry, Heslington, York, UKB.Sc. (Chemistry, Class 2.1), June 1994
Research publications:
Lloyd, D.R., Phillips, D.H., and Carmichael, P.L. (1997) Generation of putative intrastrand cross-links and strand breaks in DNA by transition metal ion-mediated oxygen radical attack. Chemical Research in Toxicology, 10, 393-400.
Lloyd, D.R., Carmichael, P.L., and Phillips, D.H. (1998) Comparison of the formation of 8-hydroxy-2'-deoxyguanosine and single- and double-strand breaks in DNA mediated by Fenton reactions. Chemical Research in Toxicology, 11, 420-427.
Lloyd, D.R. and Phillips, D.H. (1999) Oxidative DNA damage mediated by Fenton reactions: evidence for site-specific mechanisms in the formation of putative intrastrand cross-links, 8-hydroxy-2'-deoxyguanosine and double-strand breaks. Mutation Research, 424, 23-36.
Lloyd, D.R. and Hanawalt, P.C. (2000) p53-dependent global genomic repair of benzo(a)pyrene-7,8-diol-9,10-epoxide adducts in human cells. Cancer Research, 60, 517-521.
Hanawalt, P.C., Crowley, D.J., Ford, J.M., Ganesan, A.K., Lloyd, D.R., Nouspikel, T., Smith, C.A., and Tornaletti, S. (2000) Regulation of nucleotide excision repair in bacteria and mammalian cells. Biological Responses to DNA Damage, Cold Spring Harbor Press, NY.
Tornaletti, S., Maeda, L.S., Lloyd, D.R., Reines, D., and Hanawalt, P.C. (2001) Effect of thymine glycol upon transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II. Journal of Biological Chemistry, 276, 45367-45371.
Lloyd, D.R. and Hanawalt, P.C. (2002) Efficient global nucleotide excision repair of DNA adducts formed by benzo(g)chrysene is dependent upon the tumour suppressor protein p53. Cancer Research, 62, 5288-5294.
Hanawalt, P.C., Ford, J.M, and Lloyd, D.R. (2003) Functional characterization of global genomic DNA repair and its implications for cancer. Mutation Research, 544, 107-114.
Bhana, S., and Lloyd, D. R. (2008) The role of p53 in DNA damage-mediated cytotoxicity overrides its ability to regulate nucleotide excision repair in human fibroblasts. Mutagenesis, 23, 43-50.
Bhana, S., Hewer, A., Phillips, D.H., and Lloyd, D. R. (2008) p53-dependent repair of cisplatin-induced instrastrand cross-links in human cells. Mutagenesis, 23, 131-136.
Weeks, A.J., Paul, R. L., Marsden, P., Blower, P. J., and Lloyd, D. R. (2010) Radiobiological effects of hypoxia-dependent uptake of Copper-64-ATSM: enhanced DNA damage and cytotoxicity in hypoxic cells. European Journal of Nuclear Medicine, 37, 330-338.
Forthcoming publications:
Weeks, A. J., Blower, P. J., and Lloyd, D. R. Cellular uptake, nuclear accumulation, DNA damage and toxicity induced by the infection-imaging radiopharmaceutical indium-111-oxinate. Journal of Nuclear Medicine.
Weeks, A.J., Blower, P.J., and Lloyd, D.R. p53-dependent radiobiological responses to internalised indium-111 in human cells. European Journal of Nuclear Medicine.
Weeks, A. J., Lloyd, D. R. and Blower, P. J. Measurement of cellular uptake of radiopharmaceuticals in situ using the phosphorimager.
Postgraduate research supervision:
PhD supervision
Sara Bhana – PhD awarded 2006. This BBSRC-funded, award-winning student (best presentation at the UK Environmental Mutagen Society meeting 2004) is now a postdoctoral research scholar at the Paterson Institute of Cancer Research, University of Manchester. Two publications from her work submitted for publication (see “Publications”).
Amanda Weeks – PhD awarded 2008. Jointly supervised by Professor Phil Blower (now at King’s College London) on an EPSRC-funded research grant, currently writing up. One manuscript describing her work is in press, two others are in preparation (see “Forthcoming Publications”)
Catherine Hogwood – PhD awarded 2010. jointly supervised by Dr. Mark Smales. BBSRC-funded. Two manuscripts in preparation
Samuel Godfrey – jointly supervised by Dr. Peter Nicholls. Funded by Kent Alumni Scholarship Fund. Thesis submitted September 2011.
Claudia Rathje – jointly supervised by Dr. Ian Blomfield. Funded by University studentship and currently in final year.
Masters supervision
Eloise Smith – MRes awarded 2004.
Shahla Salehi – MRes awarded 2005.
Mark Swayne – MSc awarded 2010.
Danny Needham – currently writing up.
In addition, two honours thesis students were supervised at Stanford University, and over 60 undergraduate final year project students supervised at the University of Kent.
Awards and distinctions:
· Research Training Fellowship from the International Agency for Research on Cancer, 1998.
· Postgraduate Certificate of Higher Education (with special commendation), University of Kent, October 2003
· Science, Technology and Medical Studies Faculty Teaching Prize, University of Kent, June 2006.
· National Teaching Fellowship from the Higher Education Academy, September 2006.
Teaching experience and curriculum design:
Stage 1
Fundamental Chemistry and Biochemistry for Pharmacists
Fundamental Physiology and Pharmacology for Pharmacists
Chemistry for Biologists
(Both modules taught at Medway School of Pharmacy)
Stage 2
Pharmacology (module convenor)
Physiology
Stage 3
Final Year Project (module convenor)
Postgraduate
Advanced Molecular Biology (module convenor)
Radiopharmaceutics and PET Radiochemistry (specialist external lecturer at King’s College, London)
MSc Science, Communication and Society (Programme Director)
MSc Cancer Biology (Programme Director)
Tutorial/Pastoral
Personal academic tutor to over 30 undergraduate students
Member of Staff-Student Liaison Committee
Teaching qualifications:
Awarded PGCHE in September 2003 with special commendation by the Board of Examiners for the “exceptional quality of the portfolio submitted”
Publications relating to teaching:
Lloyd, D.R. (2006) Final-year projects in science communication. Centre for Bioscience Bulletin, 18, 11.
Lloyd, D.R. (2007) Involving undergraduates in outreach and science communication through final year projects in science communication. Proceedings of the Science Learning and Teaching Conference, 134-137.
Lloyd, D.R. (2008) Final year projects in communicating science. In “Student Research Projects: Guidance on Practice in the Biosciences”. Teaching Bioscience: Enhancing Learning Series, Higher Education Academy.
.
Membership of professional societies:
Full member of the US and UK Environmental Mutagen Societies, the Association for Radiation Research and the Association of National Teaching Fellows.
Other responsibilities: