IRISH NEUROLOGICAL ASSOCIATION

50th Annual Meeting

8th and 9th May 2014

Titanic Centre,

Belfast.

IRISH NEUROLOGICAL ASSOCIATION

50th Annual Meeting

8th and 9th May 2014

Titanic Centre,

Belfast.

THURSDAY 8TH MAY 2014

11.00 Registration

12.00 Lunch

12.45 Opening and Welcome

SESSION 1

Platform Presentations

O1 / 13.00 / Neuropathy phenotype in Hereditary Transthyretin Amyloidosis
Carr AS, Pelayo AL, Wechalekar AD, Whelan CJ, Gilmore JD, Hawkins PN, Reilly MM.
O2 / 13.15 / Temporal Discrimination Threshold (TDT) as an endophenotype in parkin disease (PARK2)
McKinley J, McCarthy A, Molloy A, Williams L, Kimmich O, Butler J, Kearney S, Ross O, Reilly R, O’Riordan S, Hutchinson M, Lynch T.
O3 / 13.30 / The trials and tribulations of continuous levodopa therapy
Kelly SB, Williams J, Fearon C, Magennis B, O’ Rourke K, Lynch T.
O4 / 13.45 / Diagnostic screening of POLG mutations in Ireland
Howley R, Buckley P, Loftus T, Brett FM, Farrell, MA.
O5 / 14.00 / Clinical predictors of Expanded Disability Status Scale rank change over 5-year intervals in the MSBase Registry.
Hughes S, Spelman T, McDonnell G, Hawkins S, Kee F, Butzkueven H, Gray O.

14.15 Posters, Tea and Coffee

SESSION 2

14.30 Link to ABN meeting in Millenium Centre is Cardiff and ABN Medallist Lecture

ABN Medallist lecture
Chair: Professor Geraint Fuller
Speaker: Professor Michael Hutchinson
Citation: Professor Alan Thompson

Platform Presentations: NEUROVASCULAR

O6 / 15.30 / The use of Diffusion Weighted MRI in diagnosis of Ischaemic Optic Neuropathy
Geary E, Marnane M, Cronin S.
O7 / 15.45 / Comparison of the prevalence of carotid artery ulceration on computed tomography angiography (CTA) and contrast-enhanced magnetic resonance angiography (CEMRA)
Kennedy F, Salih HMS, Ederle J, Adams M, Richards T, Brown MM, Jäger HR.
O8 / 16.00 / An Audit of Intra-arterial Interventions for Acute Ischaemic Stroke at Cork University Hospital.
Lyons S, Nicholson P, Wyse G, Fanning N, Cronin S.
O9 / 16:15 / An Audit of Fingolimod use in an MS Tertiary Referral Centre
O’Connell K, Duggan M, Buckley L, Muldowney C, Hutchinson M, Tubridy N, McGuigan C.
16.30 / Origins and Contribution of the Irish Neurological Association
Dr. Stanley Hawkins, Consultant Neurologist/Reader
Division of Medicine and Therapeutics, Queen's University Belfast


SESSION 3

Expert led poster sessions

Topic / Moderator
17:00 / Neuromuscular / Dr. John McConville
17.00 / Epilepsy / TBC
17.00 / Inflammatory / TBC
17:00 / Movement Disorder / TBC
17:00 / Neurovascular / Dr Mark McCarron
17.00 / General / TBC

SESSION 4

17.30 INA Business Meeting (Members Only)

19.30 Wine Reception / Tour of Titanic Galleries

20.00 INA Dinner

FRIDAY, 9TH MAY 2014

07.30 Neurosurgical Glioma Breakfast Meeting

Chair: Mr. Tom Flannery

08.30 Registration.
Posters, Tea and Coffee

09.00 – 10.00 Parallel Sessions: Neurosurgery, Case Series

SESSION 5

NEUROSURGERY

O12 / 09.00 / A review of outcomes of high grade gliomas in those over 70 years: a Northern Ireland unit’s experience.
Convery F, Hannon C, Flannery T, Bradley M, Herron B.
O13 / 09.10 / Outcomes of anaplastic oligodendroglial tumours pre-ASCO 2012: a population-based study
Hannan C, Harney J, Conkey D, Flannery T, Moss J, Herron B.
O14 / 09.20 / Population study of indications for neurosurgery after acute ischaemic stroke and intracerebral haemorrhage.
Olszewska D Sheehan O Marnane M, Merwick A, Hannon N, Ní Chróinín D, Callaly E, Horgan G, Duggan J, Kyne L, Dolan E, Williams D, Moroney J, Murphy S, O’Rourke K, Kelly PJ.
O15 / 09.30 / Awake Craniotomy - a multidisciplinary approach; the Belfast experience.
Trimble G, McStravick C, McKinstry S, Smyth G, Law G, Courtney H, Quigley G, Farling P, Flannery T.
O16 / 09.40 / Skull base surgery by a single surgeon – a 17 year experience in the era of supraspecialiastion
Tambirajoo K, O’Sullivan MGJ.
O17 / 09.50 / Adams Andrew McConnell (1884-1972): Pioneer of Irish Neurosurgery
Duddy JC, Kennerk B

SESSION 6

CASES/ CASE SERIES

O18 / 09.00 / A case of benign hereditary chorea with a TITF-1 gene mutation.
Mackay J, Hughes S, Kearney S.
O19 / 09.12 / Brain on fire… Not just for the young
Rutledge S, McSweeney F, Crowley P Farrell M, Elamin M, Chalissery A, O'Connor R, McGuigan C, Tubridy N.
O20 / 09.24 / Craniocervical dystonic motor overflow in parkin disease
McKinley J, McCarthy A, O’Riordan S, Hutchinson M, Lynch T.
O21 / 09.36 / MFN2 deletion founder mutation in the UK population.
Carr AS, Polke JM, Wilson J, Pelayo AL, Laura M, Nanji T, Lecky B, Vaughan J, Rankin J, Sweeny MG, Reilly MM.
O22 / 09.48 / The genetic, clinical and MRI features of CADASIL in Northern Ireland
McMacken G, McKenna E, McConville J, McKee S.
10.00 / Guest Lecture: Professor Mike McDermott, Neurosurgical Director, UCSF Gamma Knife® Radiosurgery Program, Department of Neurological Surgery, UCSF, USA.
"The role of Stereotactic Radiosurgery in Neurology & Neurosurgery"

11.00 Tea and Coffee

11:15 Neurosurgery Expert-led Poster Session

SESSION 7

PLATFORM PRESENTATIONS

O18 / 11.30 / Malformation risks of antiepileptic drug monotherapies in pregnancy: An update from the UK and Ireland Epilepsy and Pregnancy Registers.
Campbell E, Kennedy F, Russell A, Smithson WH, Parsons L, Robertson I, Irwin B, Liggan B, Delanty N, Morrison PJ, Hunt SJ, Craig J, Morrow J.
O19 / 11.45 / Long-term outcome for patients with epileptiform features on electroencephalogram
Crotty G, Chalissery A, McNamara B.
O20 / 12.00 / Economic Costs associated with an MS Relapse
O’Connell K, Kelly SB, Fogarty E, Duggan M, Buckley L, Hutchinson M, McGuigan C, Tubridy N.
O21 / 12.15 / The outcome of preconceptual counselling in women with epilepsy.
Campbell E1, Irwin B1, Cooke I2, Hunt SJ1, Craig J1, Morrow J1
12.30 / Guest Lecture: Professor Gus Baker, Professor of Neuropsychology, The Walton Centre, Liverpool, United Kingdom.
"From clinical observation to European/US Guidelines: the story of the impact of AED’s on the developing brain"

13.30 Lunch

SESSION 8

POSTER VIDEO PRESENTATIONS

P / 14.30 / Ictal Aggression – A Case Report of an Unusual Phenomenon
El-Naggar H, Doyle M, McManus E, Hutton G, Delanty N.
P / 14.35 / The ‘choreography’ of Irish dancing dyskinesia in parkin disease.
McKinley J, McCarthy A, O’Riordan S, Hutchinson M, Fung V, Lynch T.
P / 14.40 / Bilateral limb shaking transient ischaemic attack: interesting case report and literature review
Kennedy F, Richards T, Adams M, Rodriguez-Justo M, Jäger HR, Brown MM
P / 14.45 / A case of exercise-induced absence status epilepticus
Laffan A, Leahy T, Egan D, Keane K, Hennessy M.
P / 14.50 / A case of myoclonus-dystonia syndrome with epsilon sarcoglycan gene mutation.
Hughes S, Kearney S
P / 14.55 / A case Reading Epilepsy
Boucher J, Lynch J.

15.15 Announcement of Awards

15.30 Meeting close and delegates depart

POSTERS

A Neuromuscular

B Neuropathology and Neurosurgery

D Cerebrovascular

E Epilepsy

F Multiple Sclerosis

G Movement Disorder

H General Interest

A.  NEUROMUSCULAR

A1 Periodic paralysis, a phenotypic diagnosis
Akijian L, Augustine S, McCabe D, Alexander M, Murphy SM.

A2 Bent Double: Concomitant causes of camptocormia

Hoeritzauer I, McKinley J, Pang K, Kearney S.

A3 A yellow case of Guillain- Barré syndrome - IVIG the unexpected culprit!

Kee R, Kinney M, Bridgham M, Craig J.

A4 Hereditary neuropathy with liability to pressure palsies in a child: case report

Korotchikova I, McNamara B, O’Mahony O.

A5 Traumatic sciatic neuropathy and the vulnerability of the tibial segment

Laffan A, Bergin D, Lynch J.

A6 The spectrum of DOK7 congenital myasthenia in Northern Ireland

McMacken G, Carr AS, Healy E, Pang K, Palace J, Beeson D, McConville J.

A7 Bethlem Myopathy

Munteanu T, Byrne S, Lonergan R, Ferguson D, Brett F, Langan Y, Redmond J.

A8 Is Carpal Tunnel Syndrome a bilateral condition? The prevalence and characteristics of subclinical contralateral median nerve involvement in patients with carpal tunnel syndrome.

O’Brien K, O’Donnell A, Irving E, O’Connell S, Haughton G, Byrne J, Murphy E, Connell M, Ryan M, Omer T, Mullins G, Molloy F.

A9 A Cold Case - Caution When Using the Ice Pack Test for Ocular Myasthenia Gravis

Pryor A, McVerry F, Hunt SJ

A10 Do we consider myasthenia gravis as a paraneoplastic disorder?

Rutledge S, O'Riordan S, Tubridy N, McGuigan C.

A11 Sub-acute Peripheral Neuropathy and Psychosis complicating Duo-dopa therapy

Shaikhoon SS, Browne P, Hennessy M.

A12 Myotonic dystrophy presenting as a progressive leucoencephalopathy

Shaikhoon SS, Lynch JM

A13 Peripheral neuropathy in patients with diabetes mellitus: a cross-sectional study exploring prevalence, relationship with HbA1c, preferred medications and alternative diagnoses

Yap SM, Abdeen A, Khamis A

B.  NEUROPATHOLOGY AND NEUROSURGERY

B1 Intraoperative frozen sections – a review.

Brett F., Howley R., Al Zahir ZH.

B2 Timing of Elective Admissions in The National Neurosurgical Centre: Is the neurological examination affected?

McHugh FA, Boland MR, Duddy JC, Young S

B3 Massively calcified low-grade glioma- a rare case report

Shoakazemi A, Hannan C, Herron B, Quigley G, Ellison D3

C.  CEREBROVASCULAR

C1 Bilateral limb shaking transient ischaemic attack: interesting case report and literature review

Kennedy F, Richards T, Adams M, Rodriguez-Justo M, Jäger HR, Brown MM

C2 Thrombolysis in Pregnancy- Decision Making in the Dark

Doherty CMG, McCaffrey P, McGuckin P

C3 A practice survey of the Royal Victoria Hospital pre-hospital alert system for stroke thrombolysis.

Kinney M, Hunter A, McVerry F, Fulton A, Watt M

C4 The Northern Irish experience of endovascular intervention in cerebral venous sinus thrombosis (CVST).

Kinney MO, Hunt S, Droogan A, McVerry F, Burns P, Rennie I

C5 Factors Influencing Door to Needle Time for Acute Stroke Thrombolysis: Audit Results 2012-13

McVerry F, Hunter AM, Wiggam, Watt M

C6 Reversible Cerebral Vasoconstriction Syndrome- Case series and Literature review

McVerry F, Kinney M, McMonagle PJ, Craig J

D.  EPILEPSY

D1. Ictal Aggression – A Case Report of an Unusual Phenomenon

El-Naggar H, Doyle M, McManus E, Hutton G, Delanty N

D2 A case of exercise-induced absence status epilepticus

Laffan A, Leahy T, Egan D, Keane K, Hennessy M

D3 A survey of the working knowledge of the assessment and management of status epilepticus among junior medical staff in a regional neurosciences centre.

Barr S, Kinney MO, McDonnell GV, Craig J.

D4 A case Reading Epilepsy

Boucher J, Lynch J

D5 A retrospective cross sectional observational study of the aetiology and classification of epilepsy in the Republic of Ireland

El-Naggar H, McManus E, Doyle M, McCormack M, Delanty N

D6 CT as first line imaging for seizure presentation to CUH ED

Henderson E, Hannigan O, Wyse G, O'Sullivan SS

D7 Seizure management in the emergency department – how can we support improvement?

Kee R, Hoeritzauer I, Craig J, Hunt S

D8 Developing a seizure pathway: Evaluating the patient journey

Majeed MS, Alexander M, Walsh R, McCabe D, Murphy SM

D9 The new William Quarriers Scottish Epilepsy Centre (SEC) – a review of the first 12 months

Russell AJC, Oto M, Razvi S, Anderson J, Hampshire J, Hansen S, Hill J, McDade C, Gahagan G.

D10 An audit of the AAN epilepsy quality measures: How are we doing??

Williams J, Kelly S, Ferron C, Smyth S, Murray B, O’Rourke K, Reid V, Kilbride R, Lynch T

E.  NEUROINFLAMATORY – MULTIPLE SCLEROSIS

E1 Cardiac Side Effects in Patient’s Initiating Fingolimod – A Dublin Hospital Experience

Gaughan M, Delanty N, Hardiman O, Healy D, Costello L, Moroney J

E2 A Case Report of Tumefactive M.S in a patient on Finogolimod

Gaughan M, Foley M, Costello, L

E3 Endoplasmic Reticulum Stress-Associated Proteins in Saliva: Potential Biomarkers for Multiple Sclerosis?

McMahon J, Higgins E, Garvey A, Counihan T, Fitzgerald U.

E4 An Audit of the Use of Therapeutic Plasma Exchange in Neurological Disorders: The Need for Further Guidelines.

McNicholas N, Gonzalez M, Cronin S, Ryan A, Costello D, Power J, Sweeney B.

E5 Neurologists adherence to guidelines when prescribing PLEX

Peukert T, Benson G, Knipe H, Hunt S.

E6 Living with Multiple Sclerosis: Exploring the invisible and unpredictable nature of the illness

Yap SM, Sweeney B, FitzGerald P.

F.  MOVEMENT DISORDER

F1 The ‘choreography’ of Irish dancing dyskinesia in parkin disease.

McKinley J, McCarthy A, O’Riordan S, Hutchinson M, Fung V, Lynch T

F2 A case of myoclonus-dystonia syndrome with epsilon sarcoglycan gene mutation.

Hughes S, Kearney S.

F3 Ambulatory Electroencephalography and Virtual Reality Environments in Freezing of Gait in Parkinson’s Disease

Fearon C, Wächter S, Beck RB, Butler JS, Williams J, Kelly S, Magennis B, Reilly RB, Lynch T.

F4 Autonomic dysfunction and pain perception in patients with Parkinson’s disease compared to healthy controls.

Crotty G, O’Dowd ST, McNamara B, O’Sullivan SS

F5 Prevalence and Importance of Non-Motor Symptoms Amongst People with Parkinson’s Disease Compared to Controls

Kao T, Crotty G, O'Sullivan SS

F6 The clinical significance and follow-up investigations of a low serum ceruloplasmin measurement in an Irish population

Kelly DM, Crotty GF, O'Sullivan SS.

F7 Better late than never? Considering Friedreich Ataxia in late-onset progressive cerebellar ataxia

Lonergan R, Elamin M, Byrne S, Bradley D, Langan Y, Redmond J.

F8 An audit on the standards of care provided by the Bon Secours Hospital, Cork for patients with Parkinson’s disease

Yap SM, Kinirons P

F9 A clinical audit of DaTSCAN use in Cork University Hospital

ÓCorragáin O, Crotty GF, O’Sullivan SS.

G.  GENERAL INTEREST

G1 A case of granulomatous vasculopathy associated with Neurosarcoidosis.

Campbell J, Kee R, Bhattacharya D, McCarron M, Fulton A

G2 An analysis of Neurology Consultation Referrals before and after the appointment of AMAU Consultants in a tertiary hospital.

Ferguson D, Munteanu T, Lonergan R, Redmond J.

G3 Epidural Blood Patching in Intracranial Hypotension: Learning from Anaesthetic Practice

Best L, Carr A, Tedford S, Winter C, Forbes R.

G4 A Central Cause of Progressive Neuromuscular Weakness

Doherty CM, McCormick M, Forbes RB, Rennie I, McKnight K

G5 Elective Lumbar Puncture – A Survey of Patient Satisfaction

Doherty CM, Harley M, McDonnell GV

G6 Audit of Referrals to the Regional Neurology Service in Northern Ireland

Doherty CM, Hughes S, Craig J.

G7 A Sinister Case of Progressive Deafness