Supplementary figures withlegends for Mohanan et al.
Sup. Fig. 1.L1CAM expression in glioma. ONCOMINE gene microarray database ( was explored for L1CAM gene expression in glioma surgical specimens and the results of Sun et al. are displayed for different grades of glioma.19,574 genes were measured for mRNA level in glioblastoma tissue compared to normal brain samples. Each column represents an analysis of the number of samples from the glioma grade given below the column. The dots on the top and the bottom of each bar represent the maximum and minimum value, respectively. Each bar displays 90th, 75th, median, 25th and 10th percentile values. Thus, the blue box represents from 75th to 25th percentile.
Sup. Fig. 2. ADAM10 expression in glioma. ONCOMINE gene microarray database ( was explored for ADAM10 gene expression in glioma surgical specimens and the results of Sun et al. are displayed for different grades of glioma.19,574 genes were measured for mRNA level in glioblastoma tissue compared to normal brain samples. Each column represents an analysis of the number of samples from the glioma grade given below the column. The dots on the top and the bottom of each bar represent the maximum and minimum value, respectively. Each bar displays 90th, 75th, median, 25th and 10th percentile values. Thus, the blue box represents from 75th to 25th percentile.
Sup. Fig. 3. FGFR1 expression in glioma. ONCOMINE gene microarray database ( was explored for FGFR1 gene expression in glioma surgical specimens and the results of Sun et al. are displayed for different grades of glioma. FGFR1 was rankedas one of the top 7% of the genes over expressed among 19,574 genes measured for mRNA level in glioblastoma tissue compared to normal brain samples. Each columnrepresents an analysis of the number of samples from the glioma grade given below the column. The dots on the top and the bottom of each bar represent the maximum and minimum value, respectively. Each bar displays 90th, 75th, median, 25th and 10th percentile values. Thus, the blue box represents from 75th to 25th percentile.
Sup.Fig. 4.Wild-type FGFR1 expression in glioma cells. T98G and U-118 cell extracts were probed using an anti-FGFR1 monoclonal antibody by western blotting. β-actinwas used as a loading control. Film exposure was overnight in order to detect the low levels of endogenous FGFR expression.
Sup. Fig. 5.Tracks of migrating T98G/K2605 and T98G/ΔFGFR1 cells.Shown are the initial images collected during the time-lapse motility experiment of T98G/K2605 vs. T98G/ΔFGFR1 cells. The red lines are a series of red “Xs” that denote the positions of the cells that were analyzed through each subsequent time-lapse image. Thus, the ends of the red lines in the cell-free areas denote the extent of each tracked cell’s path at the end of the experiment.