STEPHEN J. PANDOL, MD
Cedars-Sinai Medical Center
8730 Alden Drive, Thalians, Suite E222
Los Angeles, CA 90048
BIOGRAPHICAL DATA:
Date of Birth:June 1, 1949, Bakersfield, CA
Education: University of California, Davis, CA
B.S., 1971
St. Louis University School of Medicine, St. Louis, MO
M.D., 1975
PROFESSIONAL EXPERIENCE AND ACADEMIC APPOINTMENTS:
Intern in Medicine, 1975-1976
Wadsworth Veterans Administration Medical Center, Los Angeles, CA
Resident in Medicine, 1976-1978
Wadsworth Veterans Administration Medical Center, Los Angeles, CA
Chief Resident in Medicine, 1978-1979
Wadsworth Veterans Administration Medical Center, Los Angeles, CA
Fellow in Gastroenterology, 1978-1979
University of California, Los Angeles/Wadsworth Veterans Administration
Clinical Associate, 1979-1982
Digestive Diseases, Nat'l Institute of Diabetes, Digestive & Kidney Diseases National Institutes of Health, Bethesda, MD
Staff Physician, 1982-1995
Department of Veterans Affairs Medical Center, San Diego, CA
Assistant Professor of Medicine, 1982-1987
University of California, San Diego, CA
Research Associate, 1984-1986
Department of Veterans Affairs Medical Center, San Diego, CA
Associate Professor of Medicine, 1987-1992
University of California, San Diego, CA
Clinical Investigator, 1987-1992
Department of Veterans Affairs Medical Center, San Diego, CA
Chief, Gastroenterology, 1992-1995
Department of Veterans Affairs Medical Center, San Diego, CA
Professor of Medicine, 1992-1995
University of California School of Medicine, San Diego, CA
Director, Research and Development, 1996-1998
West Los Angeles Veterans Administration Medical Center, Los Angeles, CA
Professor of Medicine, 1996-Present
University of California School of Medicine, Los Angeles, CA
Staff Physician, 1996-Present
Department of Veterans Affairs Medical Center, West Los Angeles, CA
Co-Director of Southern California Research Center for ALPD and Cirrhosis, 1999-Present
Professor of Molecular Toxicology, 2004-Present
University of California School of Medicine, Los Angeles, CA
Guest Professor, Southern Medical University, P.R. China, 2009-Present
Co-Director of UCLA Center for Excellence in Pancreatic Diseases, 2007-Present
Director, Basic and Translational Pancreatic Research, Cedars-Sinai Medical Center, 2012-Present
HONORS:
Phi Kappa Phi Honor Society
University of California, Davis, CA, 1970
Outstanding Undergraduate Accomplishment in Biochemistry
Department Citation, University of California, Davis, CA, 1971
Bachelor of Science Degree, With Highest Honors
University of California, Davis, CA, 1971
Alpha Omega Alpha Medical Society
St. Louis University School of Medicine, St. Louis, MO, 1975
Doctor of Medicine Degree, Cum Laude
St. Louis University School of Medicine, St. Louis, MO, 1975
Outstanding Medical Intern
Wadsworth Veterans Administration Hospital, Los Angeles, CA, 1978
Outstanding Medical Resident
Wadsworth Veterans Administration Hospital, Los Angeles, CA, 1978
Department of Medicine's 7th Annual Chief Residents' Teaching Award
University of California School of Medicine, San Diego, CA, 1993
Department of Medicine's Eighth Annual Chief Residents' Teaching Award
University of California School of Medicine, San Diego, CA, 1994
The Kaiser Permanente Award for Excellence in Teaching
Honorable Mention
Dept. of Medicine, Univ. of CA School of Medicine, San Diego, CA, 1994.
Accreditation with Commendation
JCAHO Survey
Received by Veterans Affairs Medical Center, San Diego, CA, 1995
Carey Award
Received by Veterans Affairs Medical Center, West Los Angeles, CA, 1997
Accreditation with Commendation
JCAHO Survey
Received by Veterans Affairs Medical Center, West Los Angeles, CA, 1998
BOARD REQUIREMENTS ACCOMPLISHED:
National Board of Medical Examiners, 1976
The American Board of Internal Medicine, 1978
The American Board of Internal Medicine, Gastroenterology, 1982
CERTIFICATION:
State of California, Board of Medical Quality Assurance
License Number G033954
MEMBERSHIPS:
American Association for the Advancement of Science
American Federation of Clinical Research
American Gastroenterological Association
Committee Member, Gastrointestinal Teaching Project, 1993-present
Committee Member, Gastrointestinal Research Group, 1999-present
Committee Member, Research Committee, 2002-present
American Liver Foundation
President, San Diego Chapter, 1991-1993
Vice-President, San Diego Chapter, 1993-1995
Member, Medical Advisory Committee, Los Angeles Chapter, 1999-present
American Pancreatic Association
Board Member, 2009-present
President, 2013-2014
American Physiological Society
American Society for Clinical Investigation
Counselor, 1994-1997
San Diego Gastroenterology Society
Secretary-Treasurer, 1993-1994
Vice-President, 1994-1995
President, 1995
Western Association of Physicians
Western Society for Clinical Investigation
Counselor, 1990-1993
REVIEWER FOR:
Alcohol
American Journal of Pathology
American Journal of Physiology
Biochemical Pharmacology
Biochemistry
Endocrinology
Gastroenterology
Gut
International Journal of Pancreatology
Journal of Biological Chemistry
Journal of Cell Biology
Journal of Cellular Biochemistry
Journal of Clinical Investigation
Journal of Pharmacology and Experimental Therapeutics
Life Sciences
New England Journal of Medicine
Pancreas
Peptides
Proceedings of the National Academy of Sciences, USA
Regulatory Peptides
Prostaglandins
EDITORIAL BOARD:
American Journal of Physiology Gastrointestinal and Liver Physiology
Gastroenterology
Research News
Cellular and Molecular Gastroenterology and Hepatology
CONSULTING EDITOR:
Journal of Clinical Investigation
EDITOR:
Best and Taylor's Physiological Basis of Medical Practice
Section Editor for Gastrointestinal System, 1991
American Journal of Physiology: Gastrointestinal and Liver Physiology
Associate Editor, 1993-1997
Frontiers in Gastrointestinal Sciences
Chief Editor,2010-present
GRANT SUPPORT:
19831994NIH/NIDDK – DK33010
"Pancreatic secretion and phosphatidylinositol metabolism"
19831987Veterans Affairs Career Development Award
Research Associate
19871992Veterans Affairs Career Development Award
Clinical Investigator
1991-1994Veterans Affairs Merit Review
"Pancreatic physiology and pathophysiology"
Principal Investigator: Stephen J. Pandol, M.D.
1994-1998Veterans Affairs Merit Review
"Mechanisms of acinar cell death in experimental models of pancreatitis"
Principal Investigator: Stephen J. Pandol, M.D.
1994-1998NIH/NIDDK – DK33010
"Function and subcellular nature of Ca2+ signaling"
Principal Investigator: Stephen J. Pandol, M.D.
1995-1998NIH/NIDDK – DK51476
"Mechanism of ethanol-induced pancreatitis"
Principal Investigator: Stephen J. Pandol, M.D.
1998-2002Veterans Affairs Merit Review
“Molecular mechanisms of experimental pancreatitis”
Principal Investigator: Stephen J. Pandol, M.D.
1999-2002Veterans Affairs Merit Review
“Extracellular Matrix and Apoptosis in Normal & Cancer Pancreatic Cells”
Principal Investigator: Anna S. Gukovskaya, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
1999-2003 NIH/NIAAA – 1P50 AA11999-01
“USC-UCLA Research Center for Alcoholic Liver and Pancreatic Disease” Director: Hide Tsukamoto, D.V.M., Ph.D.
Co-Director: Stephen J. Pandol, M.D.
Project IV – “Ethanol and Pancreatic Injury”
Principal Investigator: Stephen J. Pandol, M.D.
2000-2002State of California – Health and Human Services Agency
California Research Program, UC Davis 00-00776V-20071
“Regulation of Pancreatic Cancer Apoptosis by Polyphenols”
Principal Investigator: Stephen J. Pandol, M.D.
2001-2005NIH/NIAAA – T32 AA07578-01
“Training Program in Alcoholic Liver and Pancreatic Diseases”
Principal Investigator: Hide Tsukamoto, D.V.M., Ph.D.
Co-Investigator: Stephen J. Pandol, M.D.
2002-2007NIH/NIDDK – DK59508
“The Inflammatory Response of the Pancreatic Acinar cell”
Principal Investigator: Stephen J. Pandol, M.D.
2002-2007Veterans Affairs Merit Review
“Phosphatidylinositol 3-kinase and the Exocrine Pancreas”
Principal Investigator: Stephen J. Pandol, M.D.
2002-2005Veterans Affairs Merit Review
“Reactive Oxygen Species: Survival Factor in Pancreatic Cancer Cells”
Principal Investigator: Anna S. Gukovskaya, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2002-2007NIH/NIAAA – AA13847
“MAT 1A Null Mouse: Model for Alcoholic Tissue Injury”
Principal Investigator: Shelly Lu, M.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2003-2007NIH/NIDDK – DK59936
"Apoptosis and Necrosis in Pancreatitis"
Principal Investigator: Anna S. Gukovskaya, Ph.D.
Co-Investigator: Stephen J. Pandol, M.D.
2003-2007NIH/NIAAA – 1 U56 AA0114643
“Role of Alcohol In Pancreatic Acinar Cell Death”
Principal Investigator: Duane Smoot, M.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2005-2009NIH/NIAAA – T32 AA07578-02
“Training Program in Alcoholic Liver and Pancreatic Diseases”
Principal Investigator: Hide Tsukamoto, D.V.M., Ph.D.
Co-Investigator: Stephen J. Pandol, M.D.
2004-2008NIH/NIAAA – 1P60 AA11999-01
“USC-UCLA Research Center for Alcoholic Liver and Pancreatic Injury-Administrative Core”
Director: Hide Tsukamoto, D.V.M., Ph.D.
Associate Director: Stephen J. Pandol, M.D.
2004-2005PHS/NCI – 5 P01 CA42710
Center PI: Heber
UCLA CNRU Pilot Feasibility Grant
“Plant-Derived Polyphenols Reverse Pancreatic Cancer Metabolic Phenotype”
Project Principal Investigator: Stephen J. Pandol, M.D.
2005-2008NIH/NIAAA– 1P60 AA11999-01
Center PI: Tsukamoto
“USC-UCLA Research Center for Alcoholic Liver and Pancreatic Disease”
Director: Hide Tsukamoto, D.V.M., Ph.D.
Co-Director: Stephen J. Pandol, M.D.
Project IV – “Protein Kinase C and Alcoholic Pancreatitis”
Project Principal Investigator: Stephen J. Pandol, M.D.
2005-2007Private Donation: Hirshberg Foundation
“Pancreatic Cancer Metabolic Phenotype is Regulated by NADPH Oxidase”
Principal Investigator: Stephen J. Pandol, M.D.
2006-2009NIH/NIAAA –5R21AA016010-02
“Alcohol and the Exocrine Pancreas ER Stress”
Principal Investigator: Stephen J. Pandol, M.D.
2006-2008NIH/NIAAA –1R21 AA015781-01
“Plasminogen System and Alcoholic pancreatitis”
Principal Investigator: Aurelia Lugea, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2006-2010Veterans Affairs Merit Review
“NOX4, Protein Tyrosine Phosphatases, and Pancreatic Cancer Cell Survival”
Principal Investigator: Anna S. Gukovskaya, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2006-2010NIH/NCI –1R01CA119025-01
“NADPH Oxidase and pancreatic Cancer Cell Survival”
Principal Investigator: Anna S. Gukovskaya, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2006-2008NIH/NIAAA –1R03AA016008-01A1
“Urokinase-type Plasminogen Activator System and Pancreatic Stellate Cells”
Principal Investigator: Aurelia Lugea, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2006-2011NIH T32 DK07180-33
“Gastroenterology”
Director/PI: Dennis M. Jensen, M.D.
Co-Directors: Peter Anton, M.D., Stephen Pandol, M.D.
2007-2009NIH/NIAAA – R03 AA016336
“The Effect of Alcohol on NADPH Oxidase Structure in Pancreatic Stellate Cells”
Principal Investigator: Kym F. Faull, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2007-2010American Gastroenterological Association Foundation
“Bcl-2 Proteins Regulate Death Responses of Acute Pancreatitis”
Principal Investigator: Olga Mareninova, Ph.D.
Sponsor: Stephen J. Pandol, M.D.
2007-2011Veterans Affairs Merit Review
“Inflammation Mediates Necrosis in Pancreatitis”
Principal Investigator: Stephen J. Pandol, M.D.
2007-2011NIH – 1P01AT0003960-01
“UCLA Center for Excellence in Pancreatic Diseases – Project 1: Phytonutrients and Metabolism in Pancreatic Diseases”
Project Principal Investigator: Stephen J. Pandol, M.D.
2007-2011NIH – 1P01AT0003960-01
“UCLA Center for Excellence in Pancreatic Diseases”
Director: Vay Liang W. Go, M.D.
Co-Director: Stephen J. Pandol, M.D.
2008-2011NIH/NIAAA– 1R21AA017276-01
“Alcoholic Pancreatitis Results from Dysregulated Immune Response”
Project Principal Investigator: Ilya Gukovsky, Ph.D.
Co-Project Principal Investigator: Stephen J. Pandol, M.D.
2009-2014NIH – P50AA011999-11
“Southern California Research Center for Alcoholic Liver & Pancreatic Diseases and Cirrhosis”
Director: Hide Tsukamoto, D.V.M., Ph.D.
Project Principal Investigators: Stephen J. Pandol, M.D., Anna Gukovskaya, Ph.D.
2011-2016NIH – K01AA019996-01
“Smoking, Alcohol Abuse and Pancreatic Disease”
Principal Investigator: Mouad Edderkaoui, Ph.D.
Mentors: Anna Gukovskaya, Ph.D., Stephen J. Pandol, M.D.
2011-2016NIH/NIAAA– R01AA019730-01A1
“Lysosomal Damage, Impaired Autophagy and Alcoholic Pancreatitis”
Principal Investigators: Olga Mareninova, Ph.D., Ilya Gukovsky, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2011-2016NIH – R01AA019954
“Alcohol Abuse and Endoplasmic Reticulum Dysfunction in Exocrine Pancreas”
Principal Investigator: Aurelia Lugea, Ph.D.
Co-Principal Investigator: Stephen J. Pandol, M.D.
2011-2016NIH T32 DK07180-33
“Gastroenterology”
Director/PI: Dennis M. Jensen, M.D.
Co-Directors: Peter Anton, M.D., Stephen Pandol, M.D.
2012-2016Veterans Affairs Merit Review
“Smoking, Alcohol Abuse and Pancreatic Disease”
Principal Investigator: Stephen J. Pandol, M.D.
2012-2017NIH/NCI– P01CA163200-01A1
“Targeting Diet-Induced Promotion of Kras-initiated Pancreatic Adenocarcinoma-Project IV:Alcohol Abuse, Metabolic Syndrome and Desmoplasia.”
Program Director: Guido Eibl, M.D.
Project IV Principal Investigator: Stephen J. Pandol, M.D.
2014-2015CalciMedica
“Development of Orai-1 inhibitors for the treatment of acute pancreatitis”
Principal Investigator: Stephen J. Pandol, M.D
2014-2019NIH/NIAAA – P50AA011999-16
“Southern California Research Center for ALPD and Cirrhosis – Project IV: Mitochondrial alcohol metabolism mediates alcoholic pancreatitis”
Director: Hide Tsukamoto, D.V.M., Ph.D.
Project Principal Investigators: Stephen J. Pandol, M.D., Anna Gukovskaya Ph.D.
2014-2019NIH/NIDDK– P01DK098108-01A1
“Organelle Disorders in Pancreatitis”
Director: Anna Gukovskaya, Ph.D.
Project Principal Investigators: Stephen J. Pandol, M.D.
UNIVERSITY AND LOCAL COMMITTEES:
Organ Physiology Course
Taught 1st year physiology to medical students
UCSD School of Medicine, 1986-1995
Standing and Promotions
UCSD School of Medicine, 1987-1992
Chairman, 1990-1992
Core Curriculum
UCSD School of Medicine, 1988-1991
Housestaff Evaluation
Department of Medicine, UCSD School of Medicine, San Diego, 1987-1995
Quality Assurance Council
Veterans Administration Medical Center, San Diego
Chairman, 1988-1995
Total Quality Improvement Steering Committee
Veterans Administration Medical Center, San Diego, 1991-1995
Research Equipment
Veterans Administration Medical Center, San Diego, 19861995
Medical Education and Research Foundation (Board member)
Department of Medicine, UCSD School of Medicine, San Diego, 1989-present
Pharmacy and Therapeutics
Veterans Administration Medical Center, San Diego 1983-1988
Research and Development
Veterans Administration Medical Center, San Diego, CA, 19861989
Chairman, 1988-1989
Representative to the Academic Senate
Department of Medicine, UCSD School of Medicine, San Diego, 1994-1995
Annual Postgraduate Course
Topics and Advances in Internal Medicine
Department of Medicine, UCSD School of Medicine
Course Co-Director, 1990-1995
Department of Medicine Committee on Advancement and Promotion
Department of Medicine, UCSD School of Medicine, 1994-1995
Research and Development
Veterans Affairs Medical Center, West Los Angeles, 1995-1998
Quality Council
Veterans Affairs Medical Center, West Los Angeles,
Co-Chairman, 1996-1999.
Strategic Planning Committee
Veterans Affairs Medical Center, West Los Angeles, 1996-1998
Dean’s Committee
Veterans Affairs Medical Center, West Los Angeles, 1996-1998
Medical Advisory Board
Veterans Affairs Medical Center, West Los Angeles, 1996-1998
Executive Committee
Research Center for Alcoholic Liver and Pancreatic Disease, Los Angeles,
1999-present
Outreach Committee
Research Center for Alcoholic Liver and Pancreatic Disease, Los Angeles,
1999-present
Introduction to Pathology Lecture Series
Taught medical, PhD, and MS students in basic pathologic basis of diseases
USC School of Medicine, 2002-present
Pathophysiology
Taught 2nd year medical students on basic pancreatic diseases
UCLA School of Medicine, 2004-present
NATIONAL COMMITTEES:
Veterans Administration Gastroenterology Merit Review Board, 1989-1992 Chairman 1991-1992
American Society for Clinical Investigation, Council Member, 1993-1996
Undergraduate Teaching Project of the American Gastroenterological Association, 1995-2002
Gastroenterology and Hepatic Disorders Research Review Group
Department of Veterans Affairs, Chairman, 1996
Research Council for Southern California and Nevada VA Medical Centers
Chairman, 1996-1998
High School Science Teachers Project, American Society for Clinical Investigation, 1994-1997
Publications Committee, American Gastroenterological Association, 1996-1997
Flying Samaritans, 2000-2003
Gastroenterology Teaching Project of the American Gastroenterological Association, 2002-2005
Research Committee, American Gastroenterological Association, 2002-2005
Legacy Society of the American Gastroenterological Association, 2007-present
Counselor, American Pancreatic Association, 2010-present
PATENTS ISSUED:
- Compositions Comprising Plant-Derived Polyphenolic Compounds and Inhibitors of Reactive Oxygen Species and Methods of Using Thereof. Continuation-in-Part of U.S. Patent NO.: US 6,953,786, B2 Date of Patent: October 11, 2005
- Methods for Treating Pancreatitis with Curcumin Compounds and Inhibitors of Reactive Oxygen. U.S. Patent NO.: US 7,060,733, Date of Patent: June 13, 2006
- Methods and Systems for Modulating hormones and related methods, agents and compositions. US Patent Application 20120058965 Date Issued: March 8, 2012
BIBLIOGRAPHY
PEER-REVIEWED – PUBLISHED:
- Pandol SJ, Korman LY, McCarthy DM, Gardner JD. Beneficial effect of oral lithium carbonate in the treatment of pancreatic cholera syndrome. N Engl J Med 302:1403-1404, 1980.
- Richter JE, Pandol SJ, Castell DO, McCarthy DM. Gastroesophageal reflux disease in the Zollinger-Ellison syndrome. Ann Internal Med 95:37-43, 1981.
- Pandol SJ, Jensen RT, Gardner JD. Mechanism of (Tyr4) bombesin-induced desensitization in dispersed acini from guinea pig pancreas. J Biol Chem 257:12024-12029, 1982.
- Jensen RT, Gardner JD, Raufman JP, Pandol SJ, Doppman JL, Collen MJ. Zollinger-Ellison syndrome-current concepts and management. Ann Internal Med 98:59-75, 1983.
- Raufman JP, Collins SM, Pandol SJ, Korman LY, Collen MJ, Cornelius MJ, Feld MK, McCarthy DM, Gardner JD, Jensen RT. Reliability of symptoms in assessing control of gastric acid secretion in patients with Zollinger-Ellison syndrome. Gastroenterology 84:108-113, 1983.
- Jensen RT, Collen MJ, Pandol SJ, Allende HD, Raufman JP, Bissonnette BM, Duncan WC, Durgin PL, Gillin JC, Gardner JD. Cimetidine-induced impotence and breast changes in patients with gastric hypersecretory states. N Engl J Med 308:883-887, 1983.
- Pandol SJ, Sutliff VE, Jones SW, Charlton CG, O'Donohue TL, Gardner JD, Jensen RT. Action of natural glucagon on pancreatic acini: Due to contamination by previously undescribed secretagogues. Gastrointest Liver Physiol 245:G703-G710, 1983.
- Jensen RT, Pandol SJ, Collen MJ, Raufman JP, Gardner JD. Diagnosis and Management of the Zollinger-Ellison syndrome. J Clin Gastro 5 (Suppl. 1): 123-131, 1983.
- Pandol SJ, Seifert H, Thomas MW, Rivier J, Vale W. Growth hormone-releasing factor stimulates pancreatic enzyme secretion. Science 225:326-328, 1984.
- Pandol SJ, Thomas MW, Schoeffield MS, Sachs G, Muallem S. Role of calcium in cholecystokinin-stimulated phosphoinositide breakdown in exocrine pancreas. Gastrointest Liver Physiol 248: G551-G560, 1985.
- Seifert H, Sawchenko P, Chesnut J, Rivier J, Vale W, Pandol SJ. Receptor for calcitonin gene-related peptide: binding to exocrine pancreas mediates biological actions. Gastrointest Liver Physiol249:G147-G151, 1985.
- Muallem S, Schoeffield M, Pandol SJ, Sachs G. Inositol trisphosphate modification of ion transport in rough endoplasmic reticulum. Proc Natl Acad Sci USA 82:4433-4437, 1985.
- Pandol SJ, Schoeffield MS, Sachs G, Muallem S. Role of free cytosolic calcium in secretagogue-stimulated amylase release from dispersed acini from guinea pig pancreas. J Biol Chem 260:10081-10086, 1985.
- Dharmsathaphorn K, Pandol SJ. Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line. J Clin Invest77:348-54, 1986.
- Pandol SJ, Dharmsathaphorn, K., Schoeffield MS, Vale W, Rivier J. Vasoactive intestinal peptide receptor antagonist [4Cl D-Phe6, Leu17] VIP. Gastrointest Liver Physiol 250:G553-G557, 1986.
- Pandol SJ, Schoeffield MS. 1,2 diacylglycerol, protein kinase C, and pancreatic enzyme secretion. J Biol Chem261:4438-4444, 1986.
- Muallem S, Fimmel CJ, Pandol SJ, Sachs G. Regulation of free cytosolic Ca2+ in the peptic and parietal cells of the rabbit gastric gland. J Biol Chem 261:2660-2667, 1986.
- Pandol SJ, Schoeffield MS, Fimmel CJ, Muallem S. The agonist-sensitive calcium pool in the pancreatic acinar cell. Activation of plasma membrane Ca2+ influx mechanism. J Biol Chem 262:16963-16968, 1987.
- Krims PE, Pandol SJ. Free cytosolic calcium and secretagogue-stimulated initial pancreatic exocrine secretion. Pancreas 3:383-390, 1988.
- Muallem S, Schoeffield MS, Fimmel CJ. Pandol SJ. Agonist-sensitive calcium pool in the pancreatic acinar cell. I. Permeability properties. Gastrointest Liver Physiol 255:G221-228, 1988.
- Muallem S, Schoeffield MS, Fimmel CJ, Pandol SJ. Agonist sensitive calcium pool in the pancreatic acinar cell. II. Characterization of reloading. Gastrointest Liver Physiol 255:G229-G235, 1988.
- Muallem S, Beeker T, Pandol SJ. Role of Na+/ Ca2+ exchange and the plasma membrane Ca2+ pump in hormone-mediated Ca2+ efflux from pancreatic acini. J Mem Biol 102:153-162, 1988.
- Kelleher D, Pandol SJ, Kagnoff MF. Phorbol myristate acetate induces IL-2 secretion by HUT 78 cells by a mechanism independent of protein kinase C translocation. Immunology 65:351-355, 1988.
- Muallem S, Pandol SJ, Beeker TG. Calcium mobilizing hormones activate the plasma membrane Ca2+ pump of pancreatic acinar cells. J Mem Biol 106:57-69, 1988.
- Muallem S, Pandol SJ, Beeker TG. Two components of hormone-evoked calcium release from intracellular stores of pancreatic acinar cells. Biochem J 255:301-307, 1988.
- Muallem S, Pandol SJ, Beeker TG. Hormone-evoked calcium release from intracellular stores is a quantal process. J Biol Chem 264:205-212, 1989.
- Algazi MC, Chen H-S, Koss MA, Hogan DL, Steinbach J, Pandol SJ, Isenberg JI. Effect of VIP antagonist on VIP-PGE2-, and acid-stimulated duodenal bicarbonate secretion. Gastrointest Liver Physiol 256:G833-G836, 1989.
- Pandol SJ, Rodriguez G, Muallem S, Mendius K. Characteristics of intracellular calcium changes required for augmentation of phorbol ester-stimulated pancreatic enzyme secretion. Cell Calcium 10:255-262, 1989.
- Dharmsathaphorn K, Huott PA, Vongkovit P, Beuerlein G, Pandol SJ, Ammon HU. Cl- secretion induced by bile salts. A study of the mechanism of action based on cultured colonic epithelial cell line. J Clin Invest 84:945-953, 1989.
- Muallem S, Pandol SJ, Beeker TG. Modulation of agonist-activated calcium influx by extracellular pH in rat pancreatic acini. Gastrointest Liver Physiol 257:G917-G924, 1989.
- Schmidt DN, Pandol SJ. Differing effects of ethanol on in vitro stimulated pancreatic enzyme secretion in ethanol fed and control rats. Pancreas 5:27-36, 1990.
- Pandol SJ, Schoeffield-Payne MS. Cyclic GMP mediates the agonist-stimulated increase in plasma membrane calcium entry into the pancreatic acinar cells. J Biol Chem 265:12846-12853, 1990.
- Pandol SJ, Shoeffield-Payne MS. Cyclic GMP regulates free cytosolic calcium in the pancreatic acinar cell. Cell Calcium 11:477-486, 1990.
- O'Konski MS, Pandol SJ.