ATI-Women's health 41

ATI—Reproductive Cycle—Chapter 1 (1-19)

Infertility—no conception with unprotected sex for at least 12 months. Common factors—decreased sperm, ovulation DOs, tubal occlusions, and endometriosis. Meds used increase risk of multiple births > 25% Assessment (p13) Age, duration of infertility, OB hx (spontaneous abortions), Medical hx, surgical hx, sexual hx (coitus frequency, # past partners, hx STIs), occupational/environmental exposure risk, provide infor on assisted reproductive therapies (in vitro fert., embryo transfer, intrafallopian gamete transfer, surrogate partenting, adoption)

Genetic counseling—Identify clts in need of genetic counseling. Exp. Clt has Sickle cell trait, history of birth defects, <16 yrs and >35 yrs. Provide info on risk of occurrence, assist in construction of family medical histories of several generations, provide emotional support(denial, anger, grief, guilt, self blame), make referrals to support groups p13

Prenatal assessments thru—chorionic villus sampling, PUB (percutaneous umbilical blood sampling), and amniocentesis ---all have potential risks to fetus

Infertility Procedures:

Pelvic Exam—assess for vaginal or uterine anomalies

Hysterosalpinography—radiological check for patency of fallopian tubes, check for iodine and

seafood allergies.

Hysteroscopy—radiographic exam of uterus—defect, distortion, scar tissue

Laparoscopy—gas insufflation—visualize internal organs---general anesthesia used

Semen collection—used first, least invasive, 40% infertility RT men

Contraception Procedures

Vasectomy—infertility after approx. 20 ejaculations (1wk-several months)

Tubal ligation (salpingectomy)—from cutting, burning, or blocking

Hysterectomy—partial (uterus), complete (uterus, bilateral fallopian tubes and ovaries)

Contraception Assessment

BRAIDED—acronym for informed consent

B—benefits--advantages

R—risks--disadvantages

A—alternatives

I—inquires—clt ask questions

D—decisions

E—explanations—give info on selected method

D—documentation (info given U clts understanding)

Types of Contraception:

Abstinence

Adv.—most effective method, only safe sex if no genitalia contact

Disadv./Risks—required self-control, otherwise no risks

Coitus interruptus (withdrawl)—

Inst.—can have leakage of fluids from penis

Adv.—provides a form of Birth Control if no other option is available (?religious,area)

Disadv.—Lease effective method, no protections against STIs

Risks—men have to control ejaculation, fluid leakage from penis could contain sperm

Calendar Method(Rhythm)—based on sperm viable for 2-5 days & ovum for 1 day

Inst—record cycle for 6 months, subtract 18 days from # of days of shortest cycle,

Subtract 11 days from longest cycle. Fertile between these days of cycle.

Adv.—inexpensive, useful when used with other methods (BBT & cervical mucus)

Disadv.—not very reliable, requires record keeping & compliance of both partners

Risks—pregnancy from ovulation outside predicted days of cycle

Basal Body Temperature (BBT)—temp drops with ovulation

Inst.—take oral temp PRIOR to getting OOB each AM

Adv.—inexpensive, convenient, no side effects

Disadv.—inaccurate Temp interpretation (stress, fatigue, illness, alcohol, ambient temp)

Risks—unwanted pregnancy

Billings Method—cervical mucus thick/sticky, greatest stretch at ovulation (spinnbarkeit sign)

Inst.-handwash first, obtain mucus from vaginal introitus

Adv.—with practice self-eval can be very accurate, can determine ovulation during

lactation or menopause

Disadv.—women may feel uncomfortable with method

Risks—may in inaccurate if: mucous mixed w/ semen, contraceptive creams, or

discharge from infections

Condoms

Inst.—leave empty space at tip, hold rim on withdrawal, use with spermicidal cream for

Improved effectiveness.

Adv.—some protections against STIs

Disadv.—high rate of noncompliance, reduces spontaneity, must withdraw while erect

Risks—rupture/leakage, allergies to latex, use only water-soluble lubricants

Diaphragm and spermicide

Inst—get fitted, refitted q 2 yrs & with 15 wt. gain, stays in 6+ hrs after coitus, empty

Bladder prior to insertion, reapply spermicide with additional coitus

Adv.—no surgery needed, gives woman control over contraception

Disadv.—inconvenient, reduces spontaneity, additional cream needed with each coitus

Risks—NOT recommended for clts with history of TSS (toxic shock ) or UTIs

TSS is a bacterial infections. S/S: high fever, faint feeling, drop in BP, watery

diarrhea, headache, and muscle aches. Prevention: hand washing & removal of

diaphragm after 6 hrs

Combined Oral contraceptives—estrogen & progestin—suppresses ovulation, thickens mucus to

Block semen, alters uterine decidua to prevent implantation

Inst—prescription needed, consistent use required, has SE: chest pain, SOB, leg pain from a

possible clot, headache, eye problems, CVA, HTN; miss 1 pill-take 1 ASAP, miss

2—take 2 for 2 days, miss 3—skip doses for 4 days, restart new packet and use

alternate birth control

Adv—highly effective, can alleviate dysmenorrhea, reduces acne

Disadv—no STI protection, increase risks of thomoses, breast tendersness, stoke, nausea,

Headacheds, hormone-dependent cancers, can te teratogenic, exacerbates conditions

Affected by fluid retention (migraines, epilepsy, asthma, kidney/heart disease)

Risks—Do not use if >35yrs, or have history of any of the above, or smokes, decreased

effective with meds that affect liver enzymes (anticonvulsants & some antibiotics)

Minipill—oral progestins

Inst—take pill at same time daily, do not miss fill, use other form of control for 1st month

Adv—fewer side effects to combination oral contraceptives

Disadv—less effective in suppressing ovulation, increases ovarian cysts, no STI protection

Breakthrough bleeding, increases appetite

Risks: decreased effectivness with meds that affect liver enzymes (see above)

Emergency oral contraceptives (morning after pill) (high estrogen & progestin)

Inst—take within 72 hrs, take with antiemetic 1 hr prior, check for pregnancy if menstration

doesn't occur within 21 days, counsel on contraceptive methods & risky behavior

Transdermal Contraceptive patch—progesterone & ethinyl estrodiol

Inst—appy to dry skin on buttocks, abdomen, upper arm, torso (not breast area)

Adv.—consistent blood levels of hormone, avoids liver metabolism of med, not forget pill

Disadv.—No STI protection, same SE as oral contraceptives

Risks—same as oral contraceptives, avoid areas of skin rashes or lesions for application

Injectable progestins (Depo-Provera) IM injections q 11 – 13 weeks

Inst—injection during 1st 5 days of menstrual cycle & q 11 –13 wks thereafter

Adv—very effective, 4 shots/year, not impair lactation

Disadv—prolong amenorrhea/uterine bleeding, risk of thomboembolism, no STI protection

Risks—no not message injection site as may accelerate med absorption

Implantable progesin levonorgestrel (Norplant) surgicaql implantation of 6 capsules

Inst—avoid trauma to area of implantation (inner aspect of upper arm)

Adv—effective continuous contraception for 5 years, reversible

Disadv—irregular menstrual bleeding, no STI protection (use condom for STI protection)

Intrauterine device (IUD)—chemically active device, damages sperm, prevents implantation

Inst-monitor monthly after cycle to R/O migration or expulsion of device

Adv.—effective for 1-10 yrs, reversible, does not interfere with spontaneity

Disadv—increased risk for PID, uterine perforation, ectopic preg., No STI protection, report

abnormal bleeing, abdom. pain, pain w/coitus, foul discharge, fever, chills, change

in string length, or missing strings

Risk—CONTRAINDICATED if not in monogamous relationship and if never had child

Risk of bacterial vaginosis, uterine perforation, or uterine expulsion

Female Sterilization (bilateral tubal ligation)

Adv.—permanent contraception, sexual fxn unaffected

Disadv.—risks RT surgery, irreversible

Risks—ectopic pregnancy if pregnancy occurs

Male sterilization (vasectomy)

Inst—scrotal support & moderate activity post surgery, sterility delayed (20 ejaculations)

Adv—permanent, short/safe procedure, sexual fxn not impaired

Disadv—surgery, irreversible

Antepartum ATI p20f

Gestation—conception to birth

Fertilization—union of egg & sperm to form ZYGOTE—cell divisions separate into trophoblast (outer layer giving rise to placenta) & embryoblast ((inner core giving rise to embryo)

Implantation—Zygote implants into endometrium (called deciduas after inplantation) 6-10 days after conception. Usually at uterine fundus

Chorionic villi—fingerlike projections from the trophoblasts that extend into maternal blood vessels of deciduas. Place of oxygen & nutrition and waste exchange

Ovum stage (<14) –from cellular replication (morula), blastocyst formation, and differentiation into three primary germ layers (endoder/ entoderm, mesoderm, ectoderm)

Embryo stage (day 15 to 8 wks)—most critical for development, greatest risk from teratogens. Women should avoid lg groups of people to limit exposure to infections, Handwashing important

Layers of Embryo:

Endoderm/entoderm: inner most layer of cells that become internal organs (such as intestines), epithelium of respiratory tract and other organs

Mesoderm: middle layer that becomes CT, bone marrow, muscles, blood, lymph tissue, epithelial tissue, bones/teeth

Ectoderm: outer layer that develops into skin, nails, glands, CNS, PNS (peripheral NS)

Fetal Stage: (9wks to birth) viability possible >500g and 20 weeks, good chance viability >32 wks. Viability dependent on oxygenation capabilities and CNS function

4 wk—fetal heartbeat starts, body flexed, C-shaped with arm and leg buds present

8 wk—all body organs formed, 1st indication of musculoskeletal ossification

8-12wk—FHR can be heard with Doppler

12wk—sex of fetus can be determined, blood forming in marrow, kidneys able to secrete urine

16wk—face looks human, meconium present, heart muscle well-dev. Sensory organs differentiated.

20wk—preimitive Resp mov't begin, HR heard with fetoscope, quickening occurs, brain grossly

formed, vernix caseosa (protective cheese-like coating on skin) & lanugo (fine, downy hair)

24wk—body lean, but well-proportioned, lecithin (respiratory marker) begins to appear in amniotic

fluids, ability to hear.

28wk—brown fat present, eyes begin to open & close, weak suck reflex

32wk—subQfat increase, has fingernails/toenails, sense of taste present, hears sounds outside womb

38+wk—skin pink, body rounded, lanugo on shoulders & upper body only, vernix caseosa scant,

fetus receives antibodies from mother

Fetal circulation—blood oxygenated from placenta, fetal liver not in use as all nutrients from placenta

3 shunts reroute most of circulated blood past fetal lungs and liver

Ductus arteriosus—connects pulmonary artery with aorta (bypass lungs)

Foramen ovale—intra-atrial opening shunts blood from Rà L (bypass lungs)

Ductus venosus—shunts blood from unbilical vein to inferior vena cava (bypass liver)

Placenta—produces hormones needed to maintain pregnancy & performs metabolic fxns of respiration,

nutrition, excretion, and storage

Amniotic fluid—suspends the embryo/fetus and serves:

--maintain constant Temp., source of oral fluid, repository for waste, cushion to prevent injury,

allow fetal mov't & musculoskeletal devel., prevent umbilical cord compression, prevent

amnion ( inner membrane of the placenta) from adhering to the fetus.

Umbilical cord—2 arteries carry deoxygenated blood away, 1 vein carries oxygenated & nutrition to

fetus. Wharton's Jelly—surrounds cord & prevents pressure from interfering with fetal circulation.

Risk factors that can negatively impact fetal development & lead to complications:

Preterm LaboràRDS (resp. distress syndrome)

Premature rupture of membranesà fetal infection

Ectopic pregnancy

Ployhydramniosàfetal congenital anomalies & abnormal fetal presentation

Oligohydramniosà interuterine fetal death, cord compression, IUGR

Nuchal cordà fetal asphyxia

Maternal diabetesàlarge for gestational age fetus

Rh or ABO isoimmunizationà fetal hemolytic DO (erythroblastosis fetalis)

Maternal age <16 or >35-à chromosomal anbnormalities.

Teratogenic effects in utero (maternal substance abuse, chemicals, radiation exposure, infections)

Smokingà IUGR

Poor nutritionà congenital anomalies (folic acid deficiency), IUGR

Multifetal pregnancyà (dizygotic-2 ova & monozygotic-1 ova split) à abnormal attachment of

placenta, incomplete splitting of mono, tangling of cords, circulatory problems, IUGR;

3+ fetuses: restriction of blood flow available for each fetus & restrict uterine spaceàIUGR

Uteroplacental insufficiencytà IUGR, fetal distress, neonatal morbidity, fetal death

Therapeutic & Diagnostic Procedures

Abdominal & transvaginal Ultrasound—assess fetal growth & development, fetal maturity

Biosphysical profile—assess amniotic fluid volume index, fetal breathing mov'ts, body mov'ts, fetal

muscle tone, fetal heart reactivity.

Amniocentesis—assess for genetic abnormalities or fetal lung maturity

Daily fetal kick counts—3x/day, count > 3 mov'ts / 60 minutes. No mov'ts in 12 hrs-notify Dr.

Complications of fetal development

Genetic abnormalities—defective genes, Inherited DOs, chromosone anomalies, multiple

pregnancy, ABO incompatibility

Congenital anomalies—malformations that are present at birth

IUGR (intrauterine growth restriction)—failure of fetus to grow at an expected rate

Fetal death or neonatal death

Monitoring for abnormal diagnostic fetal assessments (decreased fetal mov'ts, abnormal FHR pattern, abnormally excessive or inadequate fetal growth for duration of pregnancy, encourage early & ongoing adherence or Drs recommendations and prescriptions.

Antepartum—Normal Physiological Changes of Pregnancy ATI p.33-44

Presumptive Signs of Preg—changes felt by the woman that makes her think she's pregnant

Amenorhea, M/V, fatigue, Urinary frequency, Breast changes, Quickening(Mov't felt at 16-20 wks), uterine enlargement, linea nigra, chlosasma (mask of preg), striae gravidarum, darkened areola

Probable signs—changes observed by the examiner that makes the examiner think she's pregnant

Abdominal enlargement RT changes in uterine size, shape, or position; cervical changes, Hegar's sign (softening and compressibility of lower uterus), Chadwick's sign (deepened violet-bluish color of vaginal mucosa RT increased vascularity of area), Goodell's sign (softening of cervical tip), Ballottement (rebound of unengaged fetus), Braxton Hicks contractions (painless, irregular contractions relieved by walking), positive pregnancy fest, fetal outline felt by examiner.

Positive signs—signs that can only be explained by pregnancy

Fetal heart sounds, fetal mov't palpated by experienced examiner, visual of fetus w/ultrasound

Calculation of Delivery Date:

Nagele's Rule: subtract 3 months and add 7 days + 1 year to first day of LMP (or add 9mo.+7days)

McDonald method: measure fundal height in cm from 24-34 wks + 2 weeks (cm x 8, divided by 7)

Gravity—number of pregnancies

Nulligavida—never pregnant Primigravids—first pregnancy Miltigravida—2+ pregnancies

Parity—# of pregnancies in which the fetus reaches viability, whether born alive or not.

GTPAL=Gravidity, term births (38+ wks), preterm births, abortions/miscarriages, living children

Psysiological Stgatus of Pregnant client:

Reproductive- uterus increases in size, and changes shape and position; Ovulation/menses cease

Cardiovascular-CO (cardiac output) & blood volume increase; HR increases

Respiratory-maternal O2 need increase; during 3rd trimester chest size may enlarge

Musculoskeletal—body alterations and wt. increase necessitate an adjustment in posture. Pelvic

joints relax.

Gastrointestional- N/V (may be hormonal, or increased pressure of stomach / intestines)

Renal- GFR increases; urinary frequency is common

Endocrine-placenta à an endocrine organ- (hCG, progesterone, estrogen, etc) to maintain preg.

Serum & Urine Pregnancy tests—presence of hCG(human chorionic gonadotropin) earliest biochemical marker for preg. (6-11 days in blood ; 26 days in urine) after conception following implantation;

--hCG begins w/implantation and peaks 60-70 days gestation, then declines until 140 days, then increases until term.

--Higher hCG levels indicate multifetal preg., ectopic preg, hydatidiform mole (gestational trophoblastic disease) or abnormal gestation such as Down syndrome.

--Slow increases or abnormal decreases may indicate threatened abortion

--Some meds may cause false + or — preg. results (anticonvulsants, diuretics, tranquilizers)

--urine samples should be first-voided moring specimens

Expected Vital signs

Blood pressure: same as prepreg. range 1st trimester and after 20 weeks. ­ 5-10mmHg during 2nd trimester. Position can affect BP-supine à ¯ BP due to pressure of uterus on vena cava and result in fetal hypoxia (known as: supine hyptensive syndrome of supine vena cava syndrome) S/S are: dizziness, lightheadedness, pale/clammy skin. Use wedge under one hop to alleviate pressure