Supplementary Table 1: Effect of L1CAM on Cell Cycle of Glioma Cells

Supplementary Table 1: Effect of L1CAM on cell cycle of glioma cells.

Cell Type / G1% / S% / G2%
T98G/pLKO.1 / 75.22 ± 0.09 / 23.28 ± 0.13 / 5.54 ± 1.07
T98G/shL1 / 82.48 ± 1.76 / 12.41 ± 0.95 / 7.88 ± 0.45
U-118/K1879 / 80.23 ± 1.57 / 13.90 ± 0.64 / 5.87 ± 1.49
U-118/L1LE / 69.27 ± 1.46 / 27.80 ± 1.59 / 2.94 ± 0.13

Cells were analyzed as described in Materials and Methods. Values were determined by taking the average of percentage of cells at different phases of multiple experiments ± s.e.m. Student’s T-test was performed to compare the statistical significance between various S phase values. *, p <0.05.

Supplementary Table 2: Percentage of cells at different cell cycle phases of glioma cells expressing truncated FGFR1 and its control cells.

Cell Type / G1% / S% / G2%
T98G/K2605 / 73.97 ± 2.08 / 22.69 ± 0.59 / 3.34 ± 2.68
T98G/ΔFGFR / 86.08 ± 1.845 / 12.33 ± 2.92 / 1.60 ± 1.075
U118/K2605 / 72.32 ± 2.5 / 24.44 ± 0.33 / 3.24 ± 2.54
U118/ΔFGFR / 78.61 ± 2.805 / 18.25 ± 1.44 / 3.34 ± 0.85

Cells were analyzed as described in Materials and Methods. Values were determined by taking the average of percentage of cells at different phases of multiple experiments ± s.e.m. Student’s T-test was performed to compare the statistical significance between various S phase values. *, p <0.05.

Supplementary Table 3: Percentage of cells at different cell cycle phases of

U-118/L1LE and U-118/K1879 cells incubated with peptides.

Cell Type / G1% / S% / G2%
U-118/K1879 / 80.23 ± 1.57 / 13.90 ± 0.64 / 5.87 ± 1.49
U-118/K1879
Scrambled Peptide / 81.21 ± 1.45 / 14.1 ± 0.85 / 4.7 ± 0.60
U118/K1879
Peptide A / 77.06 ± 1.24 / 12.82 ± 0.69 / 10.12 ± 1.92
U118/L1LE / 69.27 ± 1.46 / 27.80 ± 1.59 / 2.94 ± 0.13
U-118/L1LE
Scrambled Peptide / 69.54 ± 1.19 / 26.88 ± 0.67 / 3.58 ± 0.51
U-118/L1LE
Peptide A / 79.66 ± 1.27 / 15.03 ± 0.10 / 5.37 ± 1.13

Cells were analyzed as described in Materials and Methods. Values were determined by taking the average of percentage of cells at different phases of multiple experiments ± s.e.m. Student’s T-test was performed to compare the statistical significance between various S phase values. *, p <0.05.