Table 4S Neurological System Genes Not Identified As Disease Genes

Table 4S Neurological system genes not identified as disease genes.

Symbol / Accession Number / LocusLink Name
SEMA3F / NM_004186 / sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
DLX6 / NM_005222 / distal-less homeo box 6
GAS7 / NM_005890 / growth arrest-specific 7
PAX6 / NM_001604 / paired box gene 6 (aniridia, keratitis)
MIR / NM_013262 / myosin regulatory light chain interacting protein
TFAP2B / NM_003221 / transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
DYRK4 / NM_003845 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
LOC56920 / NM_020163 / semaphorin sem2
FYN / NM_002037 / FYN oncogene related to SRC, FGR, YES
SEMA3B / NM_004636 / sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
ADARB1 / NM_015833 / adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)
IGF1 / NM_000618 / insulin-like growth factor 1 (somatomedin C)
GPR124 / NM_032777 / G protein-coupled receptor 124
NTE / NM_006702 / neuropathy target esterase
APBA2 / NM_005503 / amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
MYOC / NM_000261 / myocilin, trabecular meshwork inducible glucocorticoid response
CYP46A1 / NM_006668 / cytochrome P450, family 46, subfamily A, polypeptide 1
TRIO / NM_007118 / triple functional domain (PTPRF interacting)
RTN4R / NM_023004 / reticulon 4 receptor
RP42 / NM_020640 / RP42 homolog
GPM6B / NM_005278 / glycoprotein M6B
KIAA1061 / AB028984 / KIAA1061 protein
CBLNL1 / NM_080617 / cerebellin precursor-like 1
NGFR / NM_002507 / nerve growth factor receptor (TNFR superfamily, member 16)
ZNF-U69274 / NM_014415 / zinc finger protein
MJD / NM_004993 / Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3)
NEO1 / NM_002499 / neogenin homolog 1 (chicken)
TFRC / NM_003234 / transferrin receptor (p90, CD71)
TRPC5 / NM_012471 / transient receptor potential cation channel, subfamily C, member 5
MPP5 / NM_022474 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
CRMP1 / NM_001313 / collapsin response mediator protein 1
PC-LKC / NM_017675 / protocadherin LKC
NTN4 / NM_021229 / netrin 4
WNT8B / NM_003393 / wingless-type MMTV integration site family, member 8B
MAP2 / NM_031846 / microtubule-associated protein 2
XRCC5 / NM_021141 / X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)
PAFAH1B3 / NM_002573 / platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa
OPHN1 / NM_002547 / oligophrenin 1
GSK3B / NM_002093 / glycogen synthase kinase 3 beta
APLP2 / NM_001642 / amyloid beta (A4) precursor-like protein 2
MAPRE3 / NM_012326 / microtubule-associated protein, RP/EB family, member 3
IGSF9 / NM_020789 / immunoglobulin superfamily, member 9
SCN8A / NM_014191 / sodium channel, voltage gated, type VIII, alpha
PXN / NM_002859 / paxillin
SCA2 / NM_002973 / spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2)
SLC17A6 / NM_020346 / solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
SEMA6A / NM_020796 / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
DPYSL2 / NM_001386 / dihydropyrimidinase-like 2
SEMA4G / NM_017893 / sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
PCQAP / NM_015889 / PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein
NEFH / NM_021076 / neurofilament, heavy polypeptide 200kDa
TRIM9 / NM_015163 / tripartite motif-containing 9
FLRT2 / NM_013231 / fibronectin leucine rich transmembrane protein 2
CPNE6 / NM_006032 / copine VI (neuronal)
GSS / NM_000178 / glutathione synthetase
GTPBP5 / NM_015666 / GTP binding protein 5 (putative)
JAG1 / NM_000214 / jagged 1 (Alagille syndrome)
PCDH11X / NM_032968 / protocadherin 11 X-linked
KIAA0970 / AB023187 / KIAA0970 protein
NDRG4 / NM_020465 / NDRG family member 4
RBL2 / NM_005611 / retinoblastoma-like 2 (p130)
NOPE / NM_020962 / likely ortholog of mouse neighbor of Punc E11
TJP1 / NM_003257 / tight junction protein 1 (zona occludens 1)
EYA1 / NM_172058 / eyes absent homolog 1 (Drosophila)
GDAP1 / NM_018972 / ganglioside-induced differentiation-associated protein 1
NUMBL / NM_004756 / numb homolog (Drosophila)-like
APLP1 / NM_005166 / amyloid beta (A4) precursor-like protein 1
ICAM5 / NM_003259 / intercellular adhesion molecule 5, telencephalin
LOC85865 / NM_033107 / hypothetical protein BC004923
DLX5 / NM_005221 / distal-less homeo box 5
HOXA2 / NM_006735 / homeo box A2
C7orf16 / NM_006658 / chromosome 7 open reading frame 16
RPF-1 / NM_007252 / Retina-derived POU-domain factor-1
LHX6 / NM_014368 / LIM homeobox 6
LHX3 / NM_014564 / LIM homeobox 3
APBA1 / NM_001163 / amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
SH3GL2 / NM_003026 / SH3-domain GRB2-like 2
DVL1 / NM_004421 / dishevelled, dsh homolog 1 (Drosophila)
PHYH / NM_006214 / phytanoyl-CoA hydroxylase (Refsum disease)
SPOCK2 / NM_014767 / sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
FLJ23209 / NM_024895 / hypothetical protein FLJ23209
ACCN1 / NM_001094 / amiloride-sensitive cation channel 1, neuronal (degenerin)
EFNB3 / NM_001406 / ephrin-B3
PHOX2B / NM_003924 / paired-like homeobox 2b
AREG / NM_001657 / amphiregulin (schwannoma-derived growth factor)
KIAA0937 / AB023154 / KIAA0937 protein
NRXN2 / NM_015080 / neurexin 2
TRIM3 / NM_006458 / tripartite motif-containing 3
GPR63 / NM_030784 / G protein-coupled receptor 63
PRDM13 / NM_021620 / PR domain containing 13
QKI / AF142419 / quaking homolog, KH domain RNA binding (mouse)
PPP2R5D / NM_006245 / protein phosphatase 2, regulatory subunit B (B56), delta isoform
PCDHB2 / NM_018936 / protocadherin beta 2
SEMA5A / NM_003966 / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
PCDHB3 / NM_018937 / protocadherin beta 3
PCDHB15 / NM_018935 / protocadherin beta 15
THBS4 / NM_003248 / thrombospondin 4
SIAT8D / NM_005668 / sialyltransferase 8D (alpha-2, 8-polysialyltransferase)
DPYSL3 / NM_001387 / dihydropyrimidinase-like 3
DBN1 / NM_080881 / drebrin 1
FGF12 / NM_021032 / fibroblast growth factor 12
HES1 / NM_005524 / hairy and enhancer of split 1, (Drosophila)
BBX / NM_020235 / bobby sox homolog (Drosophila)
ADAM23 / NM_003812 / a disintegrin and metalloproteinase domain 23
TLX2 / NM_016170 / T-cell leukemia, homeobox 2
RTN4 / NM_020532 / reticulon 4
OTX1 / NM_014562 / orthodenticle homolog 1 (Drosophila)
PRDM2 / NM_012231 / PR domain containing 2, with ZNF domain
MTR / NM_000254 / 5-methyltetrahydrofolate-homocysteine methyltransferase
ARTN / NM_057160 / artemin
NRP2 / NM_003872 / neuropilin 2
KLF7 / NM_003709 / Kruppel-like factor 7 (ubiquitous)
GDA / NM_004293 / guanine deaminase
EDG2 / NM_057159 / endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
PCDHB12 / NM_018932 / protocadherin beta 12
LHX4 / NM_033343 / LIM homeobox 4
LOC119587 / BC036789 / hypothetical protein LOC119587
ACVR2 / NM_001616 / activin A receptor, type II
OCRL / NM_000276 / oculocerebrorenal syndrome of Lowe
CNTFR / NM_147164 / ciliary neurotrophic factor receptor
MGC4238 / NM_032332 / hypothetical protein MGC4238
NEUROD4 / NM_021191 / neurogenic differentiation 4
OTX3 / NM_147192 / orthodenticle homolog 3 (Drosophila)
ZNF335 / NM_022095 / zinc finger protein 335
GCM2 / NM_004752 / glial cells missing homolog 2 (Drosophila)
DOK4 / NM_018110 / docking protein 4
BMP4 / NM_130851 / bone morphogenetic protein 4
SLC25A19 / NM_021734 / solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19
PSPN / NM_004158 / persephin
MGC2656 / NM_024509 / hypothetical protein MGC2656
GLIS2 / NM_032575 / Kruppel-like zinc finger protein GLIS2
OMG / NM_002544 / oligodendrocyte myelin glycoprotein
OMD / NM_005014 / osteomodulin
ADORA2A / NM_000675 / adenosine A2a receptor
NAG14 / NM_022143 / NAG14 protein
TMOD2 / NM_014548 / tropomodulin 2 (neuronal)
ELAVL3 / NM_001420 / ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
OLFM1 / NM_014279 / olfactomedin 1
NPAS1 / NM_002517 / neuronal PAS domain protein 1
LHX1 / NM_005568 / LIM homeobox 1
POU3F2 / NM_005604 / POU domain, class 3, transcription factor 2
DLG4 / NM_001365 / discs, large (Drosophila) homolog 4
NMU2R / NM_020167 / neuromedin U receptor 2
CHRM3 / NM_000740 / cholinergic receptor, muscarinic 3
LGR6 / AB049405 / leucine-rich repeat-containing G protein-coupled receptor 6
DCAMKL1 / NM_004734 / doublecortin and CaM kinase-like 1
EPHB2 / NM_017449 / EphB2
MKRN1 / NM_013446 / makorin, ring finger protein, 1
NUMB / NM_003744 / numb homolog (Drosophila)
TRIM45 / NM_025188 / tripartite motif-containing 45
NGFB / NM_002506 / nerve growth factor, beta polypeptide
C5orf13 / NM_004772 / chromosome 5 open reading frame 13
MSI1 / NM_002442 / musashi homolog 1 (Drosophila)
HEY2 / NM_012259 / hairy/enhancer-of-split related with YRPW motif 2
SEMA4F / NM_004263 / sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
EGLN1 / NM_022051 / egl nine homolog 1 (C. elegans)
TBR1 / NM_006593 / T-box, brain, 1
MOG / NM_002433 / myelin oligodendrocyte glycoprotein
MTCH1 / NM_014341 / mitochondrial carrier homolog 1 (C. elegans)
ADAM10 / NM_001110 / a disintegrin and metalloproteinase domain 10
SEMA6D / NM_153618 / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
FGF5 / NM_004464 / fibroblast growth factor 5
FGF2 / NM_002006 / fibroblast growth factor 2 (basic)
EGF / NM_001963 / epidermal growth factor (beta-urogastrone)
FLJ90440 / NM_153377 / hypothetical protein FLJ90440
DHH / NM_021044 / desert hedgehog homolog (Drosophila)
ZIC5 / NM_033132 / Zic family member 5 (odd-paired homolog, Drosophila)
HDC / NM_002112 / histidine decarboxylase
REC14 / NM_025234 / recombination protein REC14
SIAT8B / NM_006011 / sialyltransferase 8B (alpha-2, 8-sialyltransferase)
SH3GL3 / NM_003027 / SH3-domain GRB2-like 3
ADCYAP1 / NM_001117 / adenylate cyclase activating polypeptide 1 (pituitary)
TCF4 / NM_003199 / transcription factor 4
LOC126147 / NM_145807 / hypothetical protein BC018697
SEMA6C / NM_030913 / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
EFNA3 / NM_004952 / ephrin-A3
KCNN3 / NM_002249 / potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
SRGAP2 / NM_014850 / SLIT-ROBO Rho GTPase activating protein 2
HT017 / NM_020678 / HT017 protein
BOC / NM_033254 / brother of CDO
SLIT2 / NM_004787 / slit homolog 2 (Drosophila)
GFRA3 / NM_001496 / GDNF family receptor alpha 3
MSN / NM_002444 / moesin
ST18 / NM_014682 / suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
SHC3 / NM_016848 / neuronal Shc
NR6A1 / NM_033334 / nuclear receptor subfamily 6, group A, member 1
PAL / NM_015613 / DKFZP434K091 protein
PSAP / NM_002778 / prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)
FEZ1 / NM_005103 / fasciculation and elongation protein zeta 1 (zygin I)
NEPH2 / NM_032531 / NEPH2
PLCB3 / NM_000932 / phospholipase C, beta 3 (phosphatidylinositol-specific)
DOC2A / NM_003586 / double C2-like domains, alpha
CTF1 / NM_001330 / cardiotrophin 1
CDH8 / NM_001796 / cadherin 8, type 2
PTS / NM_000317 / 6-pyruvoyltetrahydropterin synthase
MBP / NM_002385 / myelin basic protein
POU4F2 / NM_004575 / POU domain, class 4, transcription factor 2
GMFB / NM_004124 / glia maturation factor, beta
ZIC1 / NM_003412 / Zic family member 1 (odd-paired homolog, Drosophila)
ROBO4 / NM_019055 / roundabout homolog 4, magic roundabout (Drosophila)
ROBO2 / AB046788 / roundabout, axon guidance receptor, homolog 2 (Drosophila)
NRGN / NM_006176 / neurogranin (protein kinase C substrate, RC3)
DRB1 / NM_152945 / developmentally regulated RNA-binding protein 1
FMN2 / NM_020066 / formin 2
CGI-119 / NM_016056 / CGI-119 protein
ALX3 / NM_006492 / aristaless-like homeobox 3
KIAA1246 / AB033072 / KIAA1246 protein
UNC5D / NM_080872 / unc-5 homolog D (C. elegans)
NRG1 / NM_013956 / neuregulin 1
DYRK1A / NM_001396 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
KCNJ6 / NM_002240 / potassium inwardly-rectifying channel, subfamily J, member 6
DPYSL5 / NM_020134 / dihydropyrimidinase-like 5
ISL2 / NM_145805 / ISL2 transcription factor, LIM/homeodomain, (islet-2)
ZNF384 / NM_133476 / zinc finger protein 384
S100A6 / NM_014624 / S100 calcium binding protein A6 (calcyclin)
CCR5 / NM_000579 / chemokine (C-C motif) receptor 5
FGF11 / NM_004112 / fibroblast growth factor 11
NFIA / NM_005595 / nuclear factor I/A
MYT1L / AF036943 / myelin transcription factor 1-like
NEUROD1 / NM_002500 / neurogenic differentiation 1
VSNL1 / NM_003385 / visinin-like 1
EN1 / NM_001426 / engrailed homolog 1
NEURL / NM_004210 / neuralized-like (Drosophila)
ADORA1 / NM_000674 / adenosine A1 receptor
HESX1 / NM_003865 / homeo box (expressed in ES cells) 1
HEYL / NM_014571 / hairy/enhancer-of-split related with YRPW motif-like
PLXNB1 / NM_002673 / plexin B1
SCRG1 / NM_007281 / scrapie responsive protein 1
CMYA5 / NM_153610 / cardiomyopathy associated 5
FABP7 / NM_001446 / fatty acid binding protein 7, brain
DCBLD1 / BC035671 / discoidin, CUB and LCCL domain containing 1
NEUROD6 / NM_022728 / neurogenic differentiation 6
SHH / NM_000193 / sonic hedgehog homolog (Drosophila)
OSR2 / NM_053001 / odd-skipped-related 2A protein
C14orf146 / NM_152447 / chromosome 14 open reading frame 146
PHOX2A / NM_005169 / paired-like (aristaless) homeobox 2a
OTX2 / NM_021728 / orthodenticle homolog 2 (Drosophila)
RET / NM_000323 / ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
FRS2 / NM_006654 / fibroblast growth factor receptor substrate 2
SMPD1 / NM_000543 / sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)
NAB2 / NM_005967 / NGFI-A binding protein 2 (EGR1 binding protein 2)
FOXI1 / NM_012188 / forkhead box I1
PPT2 / NM_138717 / palmitoyl-protein thioesterase 2
GBX2 / NM_001485 / gastrulation brain homeo box 2
CHRM1 / NM_000738 / cholinergic receptor, muscarinic 1
GFRA2 / NM_001495 / GDNF family receptor alpha 2
STAT3 / NM_139276 / signal transducer and activator of transcription 3 (acute-phase response factor)
SEMA4C / NM_017789 / sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SHOX2 / NM_006884 / short stature homeobox 2
DKFZp566D234 / NM_020116 / hypothetical protein DKFZp566D234
HATH6 / NM_032827 / basic helix-loop-helix transcription factor 6
SOX14 / NM_004189 / SRY (sex determining region Y)-box 14
LETM1 / NM_012318 / leucine zipper-EF-hand containing transmembrane protein 1
PTK2 / NM_005607 / PTK2 protein tyrosine kinase 2
LDB2 / NM_001290 / LIM domain binding 2
BTD / NM_000060 / biotinidase
YWHAG / NM_012479 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
DKFZP564D166 / NM_025185 / putative ankyrin-repeat containing protein
ALK / NM_004304 / anaplastic lymphoma kinase (Ki-1)
GRIK1 / NM_000830 / glutamate receptor, ionotropic, kainate 1
CDK5R2 / NM_003936 / cyclin-dependent kinase 5, regulatory subunit 2 (p39)
ENC1 / NM_003633 / ectodermal-neural cortex (with BTB-like domain)
NHLH1 / NM_005598 / nescient helix loop helix 1
NINJ2 / NM_016533 / ninjurin 2
AQP4 / NM_001650 / aquaporin 4
GAP43 / NM_002045 / growth associated protein 43
CALB2 / NM_001740 / calbindin 2, 29kDa (calretinin)
ATOH1 / NM_005172 / atonal homolog 1 (Drosophila)
IL16 / NM_172217 / interleukin 16 (lymphocyte chemoattractant factor)
ARNT2 / NM_014862 / aryl-hydrocarbon receptor nuclear translocator 2
SYNPO2 / AJ010482 / synaptopodin 2
KIAA0514 / NM_014696 / KIAA0514 gene product
LRRN3 / NM_018334 / leucine rich repeat neuronal 3
PCP4 / NM_006198 / Purkinje cell protein 4
KIAA0843 / NM_014945 / KIAA0843 protein
MGC3103 / NM_024036 / hypothetical protein MGC3103
CNP / NM_033133 / 2',3'-cyclic nucleotide 3' phosphodiesterase
MGC24995 / NM_153703 / hypothetical protein MGC24995
UGT8 / NM_003360 / UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)
SIAH1 / NM_003031 / seven in absentia homolog 1 (Drosophila)
ZIC4 / NM_032153 / Zic family member 4
MLP / NM_023009 / MARCKS-like protein
PROP1 / NM_006261 / prophet of Pit1, paired-like homeodomain transcription factor
CLC_2 / NM_013246 / MISSING
FOXG1B / NM_005249 / forkhead box G1B
PNMA1 / NM_006029 / paraneoplastic antigen MA1
KIAA1354 / NM_018847 / KIAA1354 protein
TGIF / NM_170695 / TGFB-induced factor (TALE family homeobox)
NHLH2 / NM_005599 / nescient helix loop helix 2
PVRL3 / NM_015480 / poliovirus receptor-related 3
NDN / NM_002487 / necdin homolog (mouse)
PCDHB16 / NM_020957 / protocadherin beta 16
NEUROG2 / NM_024019 / neurogenin 2
LOC151636 / NM_138287 / rhysin 2
MAFB / NM_005461 / v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
ZNF238 / NM_006352 / zinc finger protein 238
DKFZp547M2010 / NM_173078 / hypothetical protein DKFZp547M2010
TNRC3 / NM_005878 / trinucleotide repeat containing 3
LRP15 / NM_052953 / hypothetical protein LRP15
JRK / NM_003724 / jerky homolog (mouse)
CHRM2 / NM_000739 / cholinergic receptor, muscarinic 2
MAB21L2 / NM_006439 / mab-21-like 2 (C. elegans)
NTF3 / NM_002527 / neurotrophin 3
NEUROG1 / NM_006161 / neurogenin 1