Summary of Clinical features and Laboratory Results in Patients with Positive Intraocular Test (16 Toxoplasma, 6 Herpesviridae related).
Laboratory Results
Case No/ age (years) / Immune status / Duration of symptoms before intraocular sampling / Intraocular inflammation
AC / Clinical findings/site of retinal necrosis/ area of chorioretinitis / PCR analysis / Goldmann Witmer coefficient/
Serology: IgMToxo if present, IgG Toxo
Pathogen
Toxoplasma gondii
1/ 35 / Active C Hepatitis (IS) / 4 M / P / Panuveitis, nasal, focal/ 6DP / Toxo Pos
PCR VZV + / Toxo Neg
VZV Pos/ coeff 2.19
IgM Toxo+
2/ 14 / - / 7ds / P / Panuveitis, , Vascularitis, hyalitis +,papilloedema/ ST, focalperipheral/ 4DP / Toxo Pos / Toxo Neg
HSV Pos/coeff 3.4
IgM-
3/ 72 / Systemic corticotherapy Prednisolone 10mg/d / 2 M / P / Panuveitis, hyalitis 3+, focal, post pole /NC / Toxo Pos / Toxo Pos/ 2.9
4/ 68 / - / 21ds / P / Panuveitis, hyalite nil, Vasculitis/ nasal, focal/ 1/2 DP / Toxo Pos / Toxo Pos/ 3.9
IgM Toxo+
5/ 24 / - / <7ds / P / Panuveitis, focal, ST/ NC / Toxo Pos / Toxo Neg
IgM Toxo+
6/59 / - / 7ds / P / Tyndall ½+, focal post pole /NC / Toxo Pos / Toxo Pos/ 2.26
IgM Toxo+
7/59 / Bone marrow transplantation, neutropenia
(IS) / 3M / P / Tyndall+, hyalitis2+/ focal, nasal/ >3DP / Toxo Pos / Toxo Pos/ 4.59
IgG 300
8/51 / - / 48h
ATCD 1995 / P / Panuveitis granul, old sup lesions, hyalitis++/ 2DP / Toxo Pos / Toxo Neg
IgG 44
9/37 / - / 21ds / P / Panuveitis, , hyalitis+++, 1 old scar/ sup focal, / 1 DP / Toxo Pos / Toxo Pos/ 2.4
IgG 87
10/35 / - / 1 M / P / Panuveitis, supfocal/ 7 DP / Toxo Pos / Toxo Pos/ 5
HSV Pos/ coff 2.5
11/12 / - / 19ds / N / hyalitis+, vasculitis/ ST focal/ 3DP / Toxo Pos / Toxo Pos/ 10.14
IgG 82.5
12/ 67 / - / 1 M / N / papillitis vasculitis, hyalitis+++, tyndall++/ focal, scar/ 4DP / Toxo Pos / Toxo Pos/ 3.27
IgG 82.5
13/ 25 / - / 6 weeks / N / hyalitis++ papillitis/ focal, post pole scar/ 3DP / Toxo Pos / Toxo Pos/ 7.85
IgG 41.3
14/ 18 / - / 7 ds / N / Papillitis, hyalitis nil
Vasculitis, Neuroretinitis / Toxo Pos / Toxo Pos/ 3.08
IgG 165
15/ 58 / - / 2 M / N / Tyndall 0, hyalitis 2+/ sup, focal/ 3 DP / Toxo Pos / Toxo Pos/ 9,7
16/18 / - / 21 ds / N / Tyndall nil/ ST lesion, scars/ 1DP / NP / Toxo Pos/ 24.78
17/ 20 / - / 15 ds / N / vasculitis papillitis/ ST, focal, scar /2DP / NP / Toxo Pos/ 8.45
18/ 59 / - / 6 ds / N / Hyalitis ½+/ multifocal focal IT, scars/ 1DP / NP / Toxo Pos/ 11.3
IgG 330
19/ 33 / - / 5 ds / P / Panuveitis granul, Hyalitis 3+/ focal, IT
2DP / Toxo neg / Toxo Pos
5.65
IgG 37.5
20/ 47 / - / 15 ds / P / Panuveitis granul,
Hyalitis 3+, /post pole lesion/ 1DP / Toxo Neg / Toxo Pos / 2.19
IgG300
21/ 62 / 15 ds / P / Panuveitis non granul/
ST, scars/ 1DP / Toxo Neg / Toxo Pos /2.45
IgG 150
22/ 29 / - / 10 ds / P / Panuveitis, papillitis/ focal, scars, Neuroretinitis/ 0 / NP / Toxo Pos / 12.23
23/ 58 / - / 15 M / N / Scar, ERM post toxo/ 0 / NP / Toxo Pos / 24
24/ 30 / - / 7 ds / N / Multifocal, SN /1/6 DP / Toxo Neg / Toxo Pos /6
Herpes Virus
25/ 63 / Breast cancer (chemotherapy) / 1 M / Retinitis / CMV Pos / CMV Pos/ 2
26/ 37 / HIV infection / 24h / Retinitis / CMV Pos / Viral neg/ IgG CMV 188
27/ 52 / HIV infection / 8 ds / PORN Retinitis / CMV Pos / Viral neg
28/ 49 / - / 4 ds / ARN / HSV1 Pos / Viral Neg
29/ 25 / 10 wks / ARN / HSV2 Pos / HSV2 Pos 29
30/ 30 / - / 7ds / ARN / VZV Pos / VZV Pos/ 34

P, present; A, absent; Neg, negative; Toxo, toxoplasmosis; IT, immusuppressive therapy or systemic corticosteroid; AC, anterior chamber inflammation; granul/ granulomateous; VC: viral charge, ds: days; M: months; wks: weeks, ARN: acute retinal necrosis; Pos: positive; Neg: negative; NP: not performed. IT: inferotemporal; ST: superotemporal; post pole: posterior pole.