Seeds / Nr of Nodes / Common with
[Lang et al., 2015]
PB-BC(Tissue) versus CTC-Tumor / Seeds / Nr of Nodes / Common with
[Lang et al., 2015]
CTC-PB versus CTC-PB
NFYA / 20 / GTF2E2, PCBD1 / NFYA / 10 / none
TMED10 / 21 / ASS1, TMED10, TMED2 / TMED10 / 10 / JMJD1C, TMED10
GABPB1 / 20 / DAZAP2, IL16 / GABPB1 / 10 / FANCG, IL16
MAFB / 20 / FOSL2 / MAFB / 20 / FOSL2, JUNB, JUND
TMEM70 / 20 / none / TMEM70 / 3 / PHC2
TYROBP / 10 / DAZAP2, TYROBP / TYROBP / 3 / TYROBP
PRKAR1A / 5 / PRKAR1A / PRKAR1A / 3 / PRKAR1A
GLO1 / 30 / IRAK1, GLO1 / GLO1 / 20 / CREBBP
KPNA4 / 5 / none / KPNA4 / 5 / MAT2B
HMGN2 / 10 / none / HMGN2 / 10 / none
DHX58 / 30 / KPNA2, TRIP6, SLC25A6, MLH1, ATP6V1G1 / DHX58 / 10 / none
HNRNPU / 30 / CDK6, HNRNPU, RBM4, HNRNPA1, FN1 / HNRNPU / 10 / RBM4
CDKN2D / 20 / CDK6 / CDKN2D / 20 / ATXN1
JUNB / 5 / none / JUNB / 3 / JUNB
WIPI1 / 10 / none / WIPI1 / 10 / ATXN1, NOTCH2NL
YWHAB / 10 / RAF1, YWHAE / YWHAB / 3 / RAF1
BECN1 / 30 / VDAC1, ATG14, MAPRE1, PPP1CA, MAPK1 / BECN1 / 5 / BCL2
PRDX1 / 5 / PRDX1 / PRDX1 / 5 / MYD88
SNRPF / 20 / SNRPE, LSM3, SRSF5, LSM5 / SNRPF / 5 / none
Each seed-subnetwork (module) includes a number of genes that are detected as differentially expressed in “CTC versus PB” and/or “CTC versus BC” according to the work of [Lang et al., 2015]. Seven seed genes are also identified as expression-responsive genes. Abbreviations: CTC, circulating tumor cells; PB, peripheral blood; BC, breast cancer.