Supplementary Table 1. Genes Upregulated in Metastases relative to primary colon tumors.

Probe Set ID / Gene Title / Gene Symbol / Met/Tumor mean fold difference / Met vs Tumor t-test
222058_at / --- / --- / 0.78 / 0.007
224346_at / --- / --- / 0.88 / 0.015
224375_at / --- / --- / 1.18 / 0.014
228279_s_at / --- / --- / 0.70 / 0.040
229148_at / --- / --- / 0.66 / 0.048
229525_at / --- / --- / 0.66 / 0.007
234380_x_at / --- / --- / 0.69 / 0.029
236682_at / --- / --- / 0.73 / 0.045
238920_at / --- / --- / 0.60 / 0.008
239603_x_at / --- / --- / 0.84 / 0.004
240241_at / --- / --- / 0.60 / 0.015
240743_at / --- / --- / 0.86 / 0.017
244226_s_at / --- / --- / 0.60 / 0.021
AFFX-BioC-3_at / --- / --- / 1.97 / 0.009
AFFX-BioC-5_at / --- / --- / 2.01 / 0.013
AFFX-r2-Ec-bioC-3_at / --- / --- / 1.72 / 0.022
AFFX-r2-Ec-bioC-5_at / --- / --- / 1.84 / 0.022
228264_at / PHACS / 1-aminocyclopropane-1-carboxylate synthase / 0.95 / 0.006
219664_s_at / DECR2 / 2,4-dienoyl CoA reductase 2, peroxisomal / 1.12 / 0.004
219870_at / ATF7IP2 / activating transcription factor 7 interacting protein 2 / 0.70 / 0.040
219986_s_at / ACAD10 / acyl-Coenzyme A dehydrogenase family, member 10 / 0.68 / 0.019
230341_x_at / ADAMTS10 / ADAM metallopeptidase with thrombospondin type 1 motif, 10 / 0.88 / 0.044
223844_at / ADAMTS13 / ADAM metallopeptidase with thrombospondin type 1 motif, 13 / 0.89 / 0.001
226325_at / ADSSL1 / adenylosuccinate synthase like 1 / 0.73 / 0.015
229028_s_at / ARL17 / ADP-ribosylation factor-like 17 / 0.79 / 0.008
211298_s_at / ALB / albumin / 3.63 / 0.039
209614_at / ADH1C / alcohol dehydrogenase 1C (class I), gamma polypeptide / 0.75 / 0.024
205640_at / ALDH3B1 / aldehyde dehydrogenase 3 family, member B1 / 0.91 / 0.048
220148_at / ALDH8A1 / aldehyde dehydrogenase 8 family, member A1 / 1.14 / 0.043
206561_s_at / AKR1B10 /// LOC340888 / aldo-keto reductase family 1, member B10 (aldose reductase) /// similar to aldo-keto reductase family 1, member B10 / 1.00 / 0.039
204151_x_at / AKR1C1 / aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) / 1.70 / 0.013
209699_x_at / AKR1C2 / aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) / 1.82 / 0.004
205477_s_at / AMBP / alpha-1-microglobulin/bikunin precursor / 1.84 / 0.036
210929_s_at / AHSG / alpha-2-HS-glycoprotein / 1.89 / 0.044
206350_at / APCS / amyloid P component, serum / 1.11 / 0.028
221009_s_at / ANGPTL4 / angiopoietin-like 4 / 0.78 / 0.040
205108_s_at / APOB / apolipoprotein B (including Ag(x) antigen) / 2.37 / 0.032
205216_s_at / APOH / apolipoprotein H (beta-2-glycoprotein I) / 1.96 / 0.048
219636_s_at / ARMC9 / armadillo repeat containing 9 / 0.68 / 0.022
217516_x_at / ARVCF / armadillo repeat gene deletes in velocardiofacial syndrome / 0.82 / 0.038
205969_at / AADAC / arylacetamide deacetylase (esterase) / 0.84 / 0.014
206743_s_at / ASGR1 / asialoglycoprotein receptor 1 / 0.78 / 0.043
1554631_at / ATM / ataxia telangiectasia mutated / 0.64 / 0.043
243323_s_at / ATBF1 / AT-binding transcription factor 1 / 0.76 / 0.024
228890_at / ATOH8 / atonal homolog 8 (Drosophila) / 0.85 / 0.022
228876_at / BAIAP2L2 / BAI1-associated protein 2-like 2 / 0.69 / 0.004
218471_s_at / BBS1 / Bardet-Biedl syndrome 1 / 0.72 / 0.039
226798_at / BCL2L13 / BCL2-like 13 (apoptosis facilitator) / 0.73 / 0.039
206119_at / BHMT / betaine-homocysteine methyltransferase / 0.60 / 0.028
231500_s_at / BOLA2 / BolA homolog 2 (E. coli) / 0.62 / 0.026
209590_at / BMP7 / bone morphogenetic protein 7 (osteogenic protein 1) / 1.26 / 0.034
233356_at / --- / BRCA2 region, mRNA sequence CG029 / 0.68 / 0.040
40020_at / CELSR3 / cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) / 0.93 / 0.038
212757_s_at / CAMK2G / calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma / 0.61 / 0.040
226424_at / CAPS / calcyphosine / 0.68 / 0.040
204920_at / CPS1 / carbamoyl-phosphate synthetase 1, mitochondrial / 0.76 / 0.029
206651_s_at / CPB2 / carboxypeptidase B2 (plasma) / 1.25 / 0.016
203081_at / CTNNBIP1 / catenin, beta interacting protein 1 / 0.60 / 0.008
214373_at / --- / CDNA clone IMAGE:3613219 / 1.55 / 0.024
231046_at / --- / CDNA clone IMAGE:4329532 / 0.90 / 0.014
226125_at / --- / CDNA clone IMAGE:4346813 / 1.40 / 0.022
238473_at / --- / CDNA clone IMAGE:4432160 / 0.68 / 0.016
227431_at / --- / CDNA clone IMAGE:4791585 / 0.82 / 0.049
235406_x_at / --- / CDNA clone IMAGE:4814828 / 0.69 / 0.005
235456_at / --- / CDNA clone IMAGE:4819084 / 1.03 / 0.016
1556195_a_at / --- / CDNA clone IMAGE:4822368 / 0.96 / 0.006
1560131_at / --- / CDNA clone IMAGE:5261865 / 0.62 / 0.043
244274_at / --- / CDNA clone IMAGE:5269446 / 0.65 / 0.026
1557521_a_at / --- / CDNA clone IMAGE:5311184 / 0.89 / 0.046
233449_at / --- / CDNA FLJ11377 fis, clone HEMBA1000442 / 0.98 / 0.013
233912_x_at / --- / CDNA FLJ11463 fis, clone HEMBA1001608 / 0.92 / 0.038
215607_x_at / --- / CDNA FLJ11511 fis, clone HEMBA1002189 / 0.67 / 0.017
234061_at / --- / CDNA FLJ12400 fis, clone MAMMA1002782 / 0.59 / 0.046
244174_at / --- / CDNA FLJ13453 fis, clone PLACE1003205 / 1.35 / 0.002
216051_x_at / --- / CDNA FLJ14139 fis, clone MAMMA1002830 / 0.93 / 0.031
233313_at / --- / CDNA FLJ14302 fis, clone PLACE2000003 / 0.87 / 0.039
231037_at / --- / CDNA FLJ26031 fis, clone PNC08078 / 0.63 / 0.024
228001_at / --- / CDNA FLJ26146 fis, clone ADG00290 / 0.99 / 0.017
1555967_at / --- / CDNA FLJ30424 fis, clone BRACE2008881, weakly similar to ZINC FINGER PROTEIN 195 / 1.04 / 0.002
233063_s_at / --- / CDNA FLJ33709 fis, clone BRAWH2007890 / 0.89 / 0.017
244723_at / --- / CDNA FLJ34659 fis, clone KIDNE2018863 / 0.67 / 0.007
214076_at / --- / CDNA FLJ39316 fis, clone OCBBF2014052 / 0.64 / 0.027
217647_at / --- / CDNA FLJ40920 fis, clone UTERU2005905 / 0.64 / 0.004
1556105_at / --- / CDNA FLJ41020 fis, clone UTERU2019163 / 0.60 / 0.000
238107_at / --- / CDNA FLJ43318 fis, clone NT2RI2018311 / 0.69 / 0.031
233235_x_at / --- / CDNA: FLJ21443 fis, clone COL04430 / 0.63 / 0.043
232970_at / --- / CDNA: FLJ23154 fis, clone LNG09460 / 0.59 / 0.031
209031_at / CADM1 / cell adhesion molecule 1 / 1.18 / 0.029
221971_x_at / CTGLF1 /CTGLF2/ CTGLF6/ CTGLF7/ CTGLF9P / centaurin, gamma-like family, member 1 /// centaurin, gamma-like family, member 6 /// centaurin, gamma-like family, member 9 pseudogene /// centaurin, gamma-like family, member 7 /// centaurin, gamma-like family, member 2 / 0.79 / 0.034
221850_x_at / CTGLF1 /// CTGLF3 /// CTGLF4 /// CTGLF5 /// CTGLF9P /// KIAA1975 / centaurin, gamma-like family, member 1 /// KIAA1975 protein similar to MRIP2 /// centaurin, gamma-like family, member 3 /// centaurin, gamma-like family, member 4 /// centaurin, gamma-like family, member 9 pseudogene /// centaurin, gamma-like family, mem / 0.74 / 0.043
231884_at / CNTROB / centrobin, centrosomal BRCA2 interacting protein / 0.86 / 0.038
218829_s_at / CHD7 / chromodomain helicase DNA binding protein 7 / 0.60 / 0.031
220193_at / C1orf113 / chromosome 1 open reading frame 113 / 0.59 / 0.035
231267_at / C1orf76 / Chromosome 1 open reading frame 76 / 0.60 / 0.044
223676_at / C1orf91 / chromosome 1 open reading frame 91 / 0.70 / 0.020
222852_at / C10orf88 / chromosome 10 open reading frame 88 / 0.96 / 0.002
237765_at / C14orf68 / chromosome 14 open reading frame 68 / 0.65 / 0.035
225981_at / C17orf28 / chromosome 17 open reading frame 28 / 0.93 / 0.001
1555095_at / C6orf123 / chromosome 6 open reading frame 123 / 0.70 / 0.044
210409_at / C6orf124 / chromosome 6 open reading frame 124 / 0.77 / 0.011
224808_s_at / C7orf20 / chromosome 7 open reading frame 20 / 0.94 / 0.007
207839_s_at / C9orf127 / chromosome 9 open reading frame 127 / 0.74 / 0.015
225817_at / CGNL1 / cingulin-like 1 / 0.89 / 0.009
216296_at / CLTA / clathrin, light chain (Lca) / 0.66 / 0.012
208474_at / CLDN6 / claudin 6 / 0.75 / 0.048
233519_at / --- / Clone 23637 mRNA sequence / 0.93 / 0.027
215147_at / --- / Clone 23712 mRNA sequence / 0.62 / 0.033
232495_x_at / --- / Clone 23900 mRNA sequence / 0.62 / 0.033
234049_at / --- / Clone PP1195 unknown mRNA / 0.65 / 0.037
205754_at / F2 / coagulation factor II (thrombin) / 0.93 / 0.034
228320_x_at / CCDC64 / coiled-coil domain containing 64 / 0.81 / 0.010
219873_at / COLEC11 / collectin sub-family member 11 / 1.12 / 0.001
205500_at / C5 / complement component 5 / 0.66 / 0.049
210168_at / C6 / complement component 6 / 1.02 / 0.019
206305_s_at / C8A / complement component 8, alpha polypeptide / 0.74 / 0.044
206727_at / C9 / complement component 9 / 0.95 / 0.033
206910_x_at / CFHR2 / complement factor H-related 2 / 1.08 / 0.037
1554459_s_at / CFHR3 / complement factor H-related 3 / 0.61 / 0.019
207874_s_at / CFHR4 / complement factor H-related 4 / 0.78 / 0.018
37020_at / CRP / C-reactive protein, pentraxin-related / 2.39 / 0.027
223644_s_at / CRYGS / crystallin, gamma S / 0.61 / 0.040
227757_at / CUL4A / cullin 4A / 0.60 / 0.032
214630_at / CYP11B2 / cytochrome P450, family 11, subfamily B, polypeptide 2 / 0.92 / 0.029
214421_x_at / CYP2C9 / cytochrome P450, family 2, subfamily C, polypeptide 9 / 0.81 / 0.036
231704_at / CYP3A4 / Cytochrome P450, family 3, subfamily A, polypeptide 4 / 0.69 / 0.022
232494_at / CYP8B1 / cytochrome P450, family 8, subfamily B, polypeptide 1 / 1.07 / 0.021
235365_at / DFNB59 / deafness, autosomal recessive 59 / 0.65 / 0.026
212974_at / DENND3 / DENN/MADD domain containing 3 / 0.65 / 0.013
241973_x_at / DPP7 / Dipeptidyl-peptidase 7 / 0.62 / 0.006
240633_at / DOK7 / docking protein 7 / 0.83 / 0.015
227098_at / DUSP18 / dual specificity phosphatase 18 / 0.94 / 0.035
226440_at / DUSP22 / dual specificity phosphatase 22 / 0.66 / 0.002
230430_at / ENTPD2 / ectonucleoside triphosphate diphosphohydrolase 2 / 1.30 / 0.010
205977_s_at / EPHA1 / EPH receptor A1 / 0.90 / 0.025
223426_s_at / EPB41L4B / erythrocyte membrane protein band 4.1 like 4B / 0.63 / 0.023
1569867_at / EME2 / essential meiotic endonuclease 1 homolog 2 (S. pombe) / 0.82 / 0.040
230102_at / ETV5 / Ets variant gene 5 (ets-related molecule) / 0.88 / 0.027
230108_at / ERCC6 / excision repair cross-complementing rodent repair deficiency, complementation group 6 / 0.79 / 0.011
228298_at / FAM113B / family with sequence similarity 113, member B / 0.69 / 0.009
1558711_at / FAM13A1OS / family with sequence similarity 13, member A1 opposite strand / 0.64 / 0.002
230172_at / FAM14B / Family with sequence similarity 14, member B / 0.62 / 0.020
227563_at / FAM27E3 / family with sequence similarity 27, member E3 / 0.68 / 0.015
226356_at / FAM73B / family with sequence similarity 73, member B / 0.79 / 0.033
228638_at / FAM76A / Family with sequence similarity 76, member A / 1.03 / 0.044
229764_at / FAM79B / family with sequence similarity 79, member B / 0.60 / 0.021
229344_x_at / FAM80B / family with sequence similarity 80, member B / 0.66 / 0.043
228277_at / FBXL19 / F-box and leucine-rich repeat protein 19 / 0.79 / 0.009
205650_s_at / FGA / fibrinogen alpha chain / 2.31 / 0.013
204988_at / FGB / fibrinogen beta chain / 3.38 / 0.007
219612_s_at / FGG / fibrinogen gamma chain / 2.19 / 0.013
205305_at / FGL1 / fibrinogen-like 1 / 1.69 / 0.036
219907_at / FRS3 / fibroblast growth factor receptor substrate 3 / 0.63 / 0.009
232968_at / FANK1 / fibronectin type III and ankyrin repeat domains 1 / 0.68 / 0.010
206496_at / FMO3 / flavin containing monooxygenase 3 / 0.93 / 0.041
229054_at / FLJ39779 / FLJ39779 protein / 0.65 / 0.029
237591_at / FLJ42957 / FLJ42957 protein / 0.61 / 0.022
231407_s_at / FOXH1 / forkhead box H1 / 0.76 / 0.030
218818_at / FHL3 / four and a half LIM domains 3 / 0.59 / 0.039
1556542_a_at / --- / Full length insert cDNA clone YZ60H05 / 0.70 / 0.046
213383_at / --- / Full-length cDNA clone CS0DF026YC16 of Fetal brain of Homo sapiens (human) / 0.83 / 0.000
228198_s_at / FAHD2B / Fumarylacetoacetate hydrolase domain containing 2B / 0.75 / 0.005
213524_s_at / G0S2 / G0/G1switch 2 / 0.87 / 0.040
207131_x_at / GGT1 / gamma-glutamyltransferase 1 / 1.02 / 0.038
215603_x_at / GGT1 /// GGT2 /// GGT3 /// GGTL4 /// LOC653590 /// LOC728226 / gamma-glutamyltransferase 1 /// gamma-glutamyltransferase 3 /// gamma-glutamyltransferase-like 4 /// similar to gamma-glutamyltransferase 2 /// gamma-glutamyltransferase 2 / 1.29 / 0.015
229435_at / GLIS3 / GLIS family zinc finger 3 / 0.91 / 0.028
214091_s_at / GPX3 / glutathione peroxidase 3 (plasma) / 0.81 / 0.005
202967_at / GSTA4 / glutathione S-transferase A4 / 0.77 / 0.018
225672_at / GOLGA2 / golgi autoantigen, golgin subfamily a, 2 / 0.62 / 0.002
226043_at / GPSM1 / G-protein signaling modulator 1 (AGS3-like, C. elegans) / 0.78 / 0.032
204121_at / GADD45G / growth arrest and DNA-damage-inducible, gamma / 1.03 / 0.045
209410_s_at / GRB10 / growth factor receptor-bound protein 10 / 0.79 / 0.013
206204_at / GRB14 / growth factor receptor-bound protein 14 / 1.26 / 0.020
201040_at / GNAI2 / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 / 0.60 / 0.039
206697_s_at / HP / haptoglobin / 3.30 / 0.016
208470_s_at / HP /// HPR / haptoglobin /// haptoglobin-related protein / 2.36 / 0.047
242292_at / CXorf50B /// hCG_1731871 / hCG1731871 /// chromosome X open reading frame 50B / 0.89 / 0.009
210013_at / HPX / hemopexin / 1.04 / 0.031
220491_at / HAMP / hepcidin antimicrobial peptide / 1.41 / 0.009
31835_at / HRG / histidine-rich glycoprotein / 0.77 / 0.024
210387_at / HIST1H2BG / histone cluster 1, H2bg / 1.79 / 0.030