Title of study: Perioperative UtiLisation of SupplEmental Oxygen (PULSE Ox)

Researcher lead:Dr Andrew Cumpstey

Role: Research partner for PULSE OxTrial Steering Committee (TSC)

Description of Research Partner’sRole

Post / Patient and Public Involvement member of PULSE OxTrial Steering Committee
Duration / March 2018 to December2019
Expenses / Travelexpenses will be covered.
Induction / You will receive an induction about the study and about your role by a member of the study team.

The PULSE Ox Study

Normal air contains 21% oxygen but for many years anaesthetists have given patients having surgery more oxygen than this. The World Health Organisationrecommends that all patients having a general anaesthetic for surgery receive 80% oxygen as this might reduce their risk of getting an infection after their operation. However, the amount of oxygen given to patients having surgery varies widely. In our recent study, we found that some patients received less than 30% oxygen whilst others received nearer 100% oxygen throughout surgery.

In someareas of medicine, evidence suggests that giving less oxygen may be as safe or even safer than giving high amounts of oxygen. For example, patients given oxygen after a heart attack seem to do worse than those given air. There are some uncertainties about how much oxygen patients should be given whilst undergoing surgery. The PULSE Ox study aims to find out if giving patients less oxygen puts less strain on their body (such as their lungs, heart, kidneys, brain or immune system) during surgery and improve their outcomes after surgery.

We are aiming to recruit around 40 patients into the study.

Membership of the PULSE OxTrial Steering Committee

The Trial Steering Committeewill consist of patients, clinicians, researchers and other relevant stakeholders.

It is vital that this Committee includes representation from people who have previously experienced what is like to undergo major surgery to help ensure the study meets the needs of the patients we are inviting to take part in the trial.

Purpose of the Trial Steering Committee

The Trial Steering Committeewill ensure the trial runs smoothly, listening to the expertise of all the stakeholders.The Committeewill be a place for discussion and decision-making about the study. This may include reviewing the progress of the study and looking at which aspects are going well and which are not, or overseeing any necessary changes to the study protocol (the protocol is the plan for the research).All members of the Project Team Group will bring their own individual expertise.Research partner members can expect to contribute their knowledge and experience to makesure that the research team recognises the concerns and needs of patients undergoing major surgery, and takes steps to overcome these. We are looking for research partners from a range of backgrounds experiences to ensure the research is as inclusive as possible.

Main Responsibilities

This role will involve having time and confidence to read documents about research. You will need to be prepared to talk about the views of people undergoing surgery without speaking for one particular group above others - excellent listening and communication skills will be essential.

  1. To attend Trial Steering Committeemeetings

Meetings will take placetwo to three times per year over the course of thestudy (4-6 meetings total). It is likely that the meetings will be held at the University Hospital Southampton NHS Foundation Trust and ideally most would be attended in person.

  1. To deal with the paperwork of the Project Team Group

Committeemembersmay be requiredto read paperwork sent out in advance of a meeting, or give theiropinion on documents sent out between meetings – most likely via email.

  1. At meetings

Members will be asked to take part in discussionsandmake sure that a wide range of issues for people having major surgeryare discussed. You will helpensure that decisionsconsiderthe concerns of patients having major surgery.

  1. Confidentiality

Membership of the Committeeincludes respecting the confidential nature of any discussions, documents and information associated with the research study and should not be discussed with anyone outside the PULSE Ox Study team.

Additional information

  1. Ownership: The contributions of research partners will be acknowledged in any presentations and publications.Members of the Trial Steering Committeeagree that the research study is owned by University Hospital NHS Foundation trust.
  2. Payment: Travel expenses will be reimbursed.
  3. Support: We will provide ongoing support and help to allow you to contribute to this project. You can contact Caroline Barker at any point throughout your involvement with questions or queries, or if you have any concerns or complaints.

If you would like further information please contact:

Caroline Barker by phone 023 8120 4989 for an informal chat or email for further information.

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