Al-Hussein Bin Talal University

Faculty of Princess Aisheh Bint Al-Hussein For Nursing and health science

Department of Medical Laboratory Sciences

Course Syllabus

Course Information
Course Title / Pathology
Course Number / 0902234
Credit Hours / 3 hours
Instructor / Dr. Osama Yousef Althunibat
Office Hours / 11am-12.30pm Mon. &Wed.
E-mail /
Course Description
Pathology is the branch of medicine that deals with the causes and mechanisms of human diseases, Therefore it is one of main foundations of medicine, and it serves to bridge basic medical disciplines with clinical sciences.
Textbook
Title / Robbins & Cotran Pathologic Basis of Disease
Author(s) / Vinay Kumar, Abul K. Abbas and Jon Aster
Publisher / ELSEVIER
Year / 2013
Edition / 9th
Other references / Wheater's Basic Pathology: A Text, Atlas and Review of Histopathology, 5th Edition
Assessment
Assessment / Expected Due Date / Percentage
First Exam / 5th week / 20%
Second Exam / 10th week / 20%
Final Exam / As detected by the registration unit / 40%
Lab work / Quizzes, Reports and final Exam / 20%
Course Objectives / Percentage
Understand basic tissue reactions to different types of injuries / 20%
Know the etiology of major diseases / 10%
Know the pathogenesis (how) of the diseases / 20%
Describe the morphologic effects produced by the disease / 10%
Describe the effects of the disease on the function of organs / 10%
Know the outcome and possible complications of the disease / 10%
Know the diagnostic methods (specially the laboratory tests) of the disease / 20%
Teaching & Learning Methods
1. Lectures which include:
• Audio-visual materials: data show and PowerPoint presentations to show Flow chart, tables and photographs
• / Examples and Discussions.

2. Laboratory sessions which include:
Microscopy: examining laboratory prepared slides for different tissue lesions
Grossly appearance of diseased organs.
Learning Outcomes: Upon successful completion of this course, students will be able to
Related Objective(s)
1. / The learner will be able to describe the divisions of pathology.
2 / The learner will be able to describe the nature of disease and define etiology.
3 / The learner will be able to describe cellular reaction to injury.
4 / The learner will be able to explain the salient principles of inflammation and repair.
5 / The learner will be able to describe circulatory dysfunction
6 / The learner will be able to describe diseases of the heart, the blood vessels, the nervous system. the bones and joints, the endocrine system, and the respiratory system.
7 / The learner will be able to describe and contrast benign and malignant tumors.
Useful Resources
The Internet Pathology Laboratory for Medical Education (http://library.med.utah.edu/WebPath/webpath.html).
The PEIR Digital Library (http://peir2.path.uab.edu/pdl/dbra.cgi?uid=default&view_search=1)
Course Content
Weeks / Topics
1 / Introduction and Terminology
2 / Cell Injury, Cellular Responses to Injury and Cell Death
3 / Inflammation, Inflammatory Mediators, and Immune Mediated Disease
4 / Hemodynamic Disorders, Thromboembolism, and Shock
5&6 / Cardiovascular Pathology
7 / Diseases of Respiratory Tract & Pleura
8&9 / Gastrointestinal Pathology
10 / Endocrine Pathology
11 / Renal and Urinary Tract
12 / Male and Female Genital Tract and Breast Pathology
13 / Skin and Musculoskeletal Pathology
14 / Nervous System
15&16 / Neoplasia

Laboratory Schedule

Weeks / Practical/slides
1 / Introduction
2 / Cellular adaptation
Myocardium hypertrophy
Gravid uterus
Metaplastic bronchial epithelium
Atrophied uterus
Dysplastic cervical epithelium
3 / Tissue Necrosis
Coagulative necrosis
Liquefactive necrosis
Gangrenous necrosis
Caseous necrosis
Fat necrosis
Fibrinoid necrosis
4 / Acute and chronic inflammation:
Acute esophagitis
Acute Suppurative Appendicitis
Acute Hematogenous Pyelonephritis
Chronic Pyelonephritis
Chronic hepatitis
5 / Cardiovascular
Coronary artery with atherosclerotic narrowing
Coronary artery with thrombosis
Acute myocardial infarction
Hyaline arteriolosclerosis
Hyperplastic arteriolosclerosis
6 / Gastrointestinal Tract
Acute esophagitis
Barrett esophagus (GERD)
Acute Suppurative Appendicitis
Chronic Peptic Ulcer
Ulcerative Colitis Of Rectum
Crohn's disease, colon
Chronic ulcerative colitis
7 / Liver and pancreas
liver steatosis
liver Cirrhosis
Acute hepatitis
Chronic hepatitis
Hemosiderosis of liver
Cholestasis of liver
Pancreas, Cystic fibrosis
8 / Kidney
Acute Hematogenous Pyelonephritis
Chronic Pyelonephritis
Amyloidosis of kidney,
Hydronephrosis
Acute renal infarction
Acute tubular necrosis
glomerulonephritis
9 / Lung 1
Pulmonary Edema
Bronchopneumonia
Acute Pneumonia
Chronic Pneumonia
Tuberculosis
pulmonary thromboembolus
10 / Lung 2
Bronchiectasis
Bronchial asthma
pulmonary fibrosis.
Pulmonary acute congestion
Pulmonary chronic congestion
pulmonary hypertension
11 / Neoplasm (1)
Meningioma
Pituitary adenoma
Thyroid, papillary carcinoma
Bronchogenic Carcinoma
Adenocarcinoma Of Lung
Metastatic Carcinoma Of Liver
12 / Neoplasm (2)
Adenocarcinoma Of Breast
Gastric adenocarcinoma
Colon, villous adenoma,
Colon, adenocarcinoma
Lipoma
13 / Neoplasm (3)
Carcinoma Of Prostate
Prostatic hyperplasia
Adenocarcinoma Of Ovary
Osteogenic Sarcoma Of Bone
Sarcoma Of Uterus
Fibrocystic Disase Of Breast
14 / Revision
15 / Final Exam