Table S1Growth phase-associated changes in the transcriptome (≥ 2-fold)
SPy no.a / Gene / Description / Fold change wt stat/wt expb1544 / arcB / putative ornithine transcarbamylase / 107c
1542 / - / putative Xaa-His dipeptidase / 95
1543 / - / hypothetical protein / 85
1541 / arcC / putative carbamate kinase / 66
1546 / - / hypothetical protein / 63
2040 / - / hypothetical protein / 44
1547 / arcA / arginine deiminase / 41
888 / clpL / putative ATP-dependent Clp proteinase (ATP-binding subunit) / 22
1190 / citX / hypothetical protein / 20
1189 / citF / putative citrate lyase, alpha subunit / 19
1260 / - / hypothetical protein / 19
1263 / - / hypothetical protein / 19
2043 / mf / mitogenic factor / 18
1186 / citD / putative citrate lyase, gamma subunit / 18
1183 / - / putative decarboxylase, gamma chain / 17
2173 / yoxJ / hypothetical protein / 16
238 / - / hypothetical protein / 15
1188 / citE / putative citrate lyase, beta subunit / 15
1157 / - / hypothetical protein / 15
1261 / - / hypothetical protein / 15
2172 / - / hypothetical protein / 15
1509 / clpE / putative ATP-dependent protease / 14
1196 / - / putative integrase recombinase / 14
1846 / dinP / putative DNA-damage-inducible protein P / 14
1184 / - / putative decarboxylase, beta subunit / 14
1761 / grpE / putative Hsp-70 cofactor / 12
1262 / - / hypothetical protein / 12
470 / - / 67 kDa Myosin-crossreactive streptococcal antigen / 12
1265 / - / hypothetical protein / 12
2039 / speB / pyrogenic exotoxin B / 11
1264 / - / hypothetical protein / 11
1191 / oadA / putative oxaloacetate decarboxylase alpha chain / 11
1708 / lacA.1 / putative galactose-6-phosphate isomerase / 11
1763 / hrcA / putative heat shock transcription repressor protein / 11
1436 / mf3 / putative deoxyribonuclease / 11
2170 / - / hypothetical protein / 11
836 / - / hypothetical protein / 10
1759 / dnaJ / heat-shock (chaperone) protein / 10
1816 / scrB / putative sucrose-6-phosphate hydrolase / 9
1715 / copA / putative cation-transporting ATP-ase - copper transport operon / 9
1683 / glpO / putative alpha-glycerophosphate oxidase / 9
1684 / glpK / putative glycerol kinase / 9
1760 / dnaK / heat shock protein 70 / 9
511 / gloA / putative lactoylglutathione lyase / 9
1714 / copZ / putative copper chaperone - copper transport operon / 9
1156 / - / hypothetical protein / 9
838 / yknZ / hypothetical protein / 9
1710 / - / putative PTS system, enzyme IIB component / 9
1602 / - / putative transcription regulator / 8
1339 / - / hypothetical protein / 8
2110 / nrdD / putative anaerobic ribonucleoside-triphosphate reductase / 8
1604 / - / hypothetical protein / 8
1259 / - / putative transcriptional regulator / 8
1510 / mutT / putative mutator protein / 8
837 / - / putative ABC transporter (ATP-binding protein) / 8
2105 / nrdG / putative anaerobic ribonucleotide reductase activator / 8
775 / - / hypothetical protein / 8
512 / - / putative NAD(P)H-flavin oxidoreductase / 8
1599 / - / putative beta-glucosidase / 8
352 / - / putative acylphosphatase / 8
1287 / - / hypothetical protein / 7
839 / - / putative glycerophosphodiester phosphodiesterase / 7
2070 / groEL / heat shock protein (chaperonin) / 7
2106 / - / hypothetical protein / 7
939 / - / putative repressor protein - phage associated / 7
1285 / - / putative transcriptional regulator (GntR family) / 7
1531 / dpr / putative peroxide resistance protein / 7
2041 / - / hypothetical protein / 7
2037 / - / hypothetical protein / 7
513 / pepQ / putative XAA-PRO dipeptidase; X-PRO dipeptidase / 7
1845 / - / hypothetical protein / 7
2048 / mipB / putative transaldolase-like protein / 7
1603 / - / hypothetical protein / 7
1976 / msmK / multiple sugar-binding ABC transport system (ATP-binding protein) / 7
2107 / - / putative oxidoreductase / 7
183 / opuAA / putative glycine betaine proline ABC transporter (ATP-binding protein) / 7
158 / - / putative toxic anion resistance protein / 7
1959 / - / hypothetical protein / 7
1686 / - / hypothetical protein / 7
184 / opuABC / putative glycine-betaine binding permease protein / 7
1780 / - / hypothetical protein / 7
1286 / - / putative ABC transporter (ATP-binding protein) / 7
1707 / lacB.1 / putative galactose-6-phosphate isomerase / 7
159 / - / hypothetical protein / 6
552 / - / hypothetical protein / 6
185 / polA / DNA-directed DNA polymerase I / 6
1693 / - / putative reductase dehydrogenase / 6
179 / araD / putative L-ribulose 5-phosphate 4-epimerase / 6
2049 / pflD / putative pyruvate formate-lyase 2 / 6
1919 / lacD.2 / putative tagatose 1,6-diphosphate aldolase / 6
2072 / groES / heat shock protein - cochaperonin / 6
780 / mscL / putative large conductance mechanosensitive channel / 6
710 / - / conserved hypothetical protein, phage associated / 6
577 / - / hypothetical protein / 6
408 / - / hypothetical protein (similar to Human CGI-32 protein / 6
1613 / - / conserved protein - function unknown / 6
1096 / folC.1 / putative folyl-polyglutamate synthetase / 6
1600 / - / putative hyaluronidase / 6
239 / gltX / putative glutamyl-tRNA synthetase / 6
1592 / - / hypothetical protein / 6
1111 / - / putative zinc-containing alcohol dehydrogenase / 6
1682 / glpF / putative glycerol uptake facilitator / 6
395 / clpP / putative ATP-dependent protease proteolytic subunit / 6
1181 / - / hypothetical protein / 6
1711 / - / putative PTS system, enzyme IIA component / 6
802 / - / hypothetical protein / 6
2080 / nox1 / putative NADH oxidase alkyl hydroperoxidase reductase / 6
1709 / - / putative PTS system, enzyme IIC component / 6
2115 / - / hypothetical protein / 5
584 / ptsK / Hpr kinase phosphatase / 5
500 / - / hypothetical protein / 5
585 / lgt / putative prolipoprotein diacylglycerol transferase / 5
914 / - / hypothetical protein / 5
492 / - / hypothetical protein / 5
1405 / - / hypothetical protein / 5
1832 / - / hypothetical protein / 5
803 / cmk / putative cytidylate kinase / 5
716 / agaS / putative tagatose-6-phosphate aldose ketose isomerase / 5
553 / - / hypothetical protein / 5
1917 / lacE / putative PTS system, lactose-specific component IIBC / 5
1511 / - / hypothetical protein / 5
437 / - / hypothetical protein / 5
587 / - / hypothetical protein / 5
1921 / lacC.2 / putative tagatose 6-phosphate kinase / 5
997 / hylP2 / hyaluronidase - phage associated / 5
1314 / uvrB / putative excinuclease ABC (subunit B) / 5
578 / - / hypothetical protein / 5
588 / - / hypothetical protein / 5
2047 / gldA / putative glycerol dehydrogenase / 5
550 / - / hypothetical protein / 5
1922 / lacB.2 / putative galactose-6-phosphate isomerase (B subunit) / 5
1918 / lacF / putative PTS system, lactose-specific component IIA / 5
2079 / ahpC / putative alkyl hydroperoxidase / 5
801 / - / ferredoxin / 5
1192 / citC / putative citrate lyase synthetase (citrate (pro-3S)-lyase ligase) / 5
1851 / - / putative C3-degrading proteinase / 5
2177 / - / putative transcriptional regulator (TetR AcrR family) / 5
1440 / - / putative holin - phage associated / 5
2059 / pbp2A / penicillin-binding protein 2a / 5
1551 / - / conserved protein - function unknown / 5
1437 / - / hypothetical protein / 5
1029 / acoC / putative dihydrolipoamide S-acetyltransferase / 5
1817 / scrR / putative sucrose operon repressor / 5
1369 / deaD2 / putative RNA helicase / 5
1915 / salA / lantibiotic precursor / 5
1991 / trpG / anthranilate synthase component II / 5
2215 / - / hypothetical protein / 5
357 / - / hypothetical protein / 5
1779 / - / putative aminotransferase / 4
1595 / - / putative sugar-binding transport protein / 4
1031 / acoL / putative dihydrolipoamide dehydrogenase, component E3 / 4
799 / - / putative tripeptidase / 4
1097 / folE / GTP cyclohydrolase / 4
1370 / - / putative deacetylase / 4
772 / - / hypothetical protein / 4
2063 / - / hypothetical protein / 4
1789 / - / hypothetical protein / 4
265 / yloS / hypothetical protein / 4
44 / adhA / putative alcohol dehydrogenase I / 4
583 / - / hypothetical protein / 4
845 / czcD / putative cation-efflux system membrane protein / 4
1404 / - / hypothetical protein / 4
358 / - / conserved hypothetical protein (putative membrane spanning protein) / 4
2088 / - / putative cationic amino acid transporter protein / 4
428 / - / hypothetical protein / 4
1059 / - / putative phospotransferase system (PTS), enzyme II, component C / 4
127 / - / putative signal peptidase I / 4
1402 / - / hypothetical protein / 4
1083 / srtA / lantibiotic precursor / 4
1593 / - / putative sugar-binding transport protein / 4
1211 / - / hypothetical protein / 4
351 / - / hypothetical protein / 4
1064 / - / hypothetical protein / 4
1099 / folQ / dihydroneopterin aldolase / 4
1406 / sodA / superoxide dismutase (Fe Mn) / 4
751 / lig / putative DNA ligase / 4
1916 / lacG / putative phospho-beta-D-galactosidase / 4
773 / - / putative ABC transporter (ATP-binding protein) / 4
1988 / - / putative methyltransferase / 4
1788 / ybaF / hypothetical protein / 4
889 / rpiA / putative ribose 5-phosphate isomerase / 4
278 / - / hypothetical protein / 4
892 / punA / putative purine nucleoside phosphorylase / 4
1056 / - / hypothetical protein / 4
1273 / cfa / CAMP factor / 4
1956 / - / hypothetical protein / 4
280 / bacA / putative undecaprenol kinase (bacitracin resistance protein) / 4
1628 / fmt / putative methionyl tRNA formyltransferase / 4
1098 / folP / dihydropteroate synthase / 4
800 / - / putative pore-forming peptide / 4
1825 / uvrA / putative excinuclease ABC (subunit A) / 4
2125 / - / putative repressor protein - phage associated / 4
450 / - / putative metal-dependent transcriptional regulator / 4
1694 / nagA / putative N-acetylglucosamine-6-phosphate deacetylase / 4
2023 / - / hypothetical protein (mga-associated) / 4
1787 / - / putative ABC transporter (ATP-binding protein) / 4
186 / - / hypothetical protein / 4
331 / htpX / putative heat shock protein / 4
1839 / yshB / hypothetical protein / 4
1989 / - / hypothetical protein / 4
1627 / sunL / putative RNA-binding Sun protein / 4
1992 / - / hypothetical protein / 4
2025 / isp / immunogenic secreted protein precursor / 4
1284 / dnaE / putative DNA polymerase III (alpha subunit) / 4
2060 / - / hypothetical protein / 4
1161 / - / hypothetical protein / 4
266 / - / hypothetical protein / 4
1766 / - / putative phosphoglycerate mutase / 4
264 / rpe / putative ribulose-phosphate 3-epimerase / 4
1923 / lacA.2 / galactosidase acetyltransferase / 4
1026 / acoA / putative acetoin dehydrogenase (TPP-dependent) alpha chain / 4
1861 / - / putative repressor - phage associated / 4
1607 / - / hypothetical protein / 4
752 / - / hypothetical protein / 4
1020 / - / hypothetical protein / 4
2122 / int4 / putative integrase - phage associated / 4
720 / - / hypothetical protein / 4
731 / eno / putative enolase / 4
565 / tnpA / transposase / 4
646 / - / hypothetical protein / 4
1649 / pbp1A / putative penicillin-binding protein 1a / 4
226 / gpsA / putative NAD(P)H-dependent glycerol-3-phosphate dehydrogenase / 4
944 / - / hypothetical protein / 4
818 / - / hypothetical protein / 4
1193 / - / hypothetical protein / 4
653 / - / hypothetical protein / 3
187 / spf / Ferric transport regulator protein / 3
1835 / trx / putative thioredoxin / 3
1673 / - / hypothetical protein / 3
263 / - / hypothetical protein / 3
891 / arsC / putative arsenate reductase / 3
1028 / acoB / putative acetoin dehydrogenase (TPP-dependent) beta chain / 3
1949 / - / hypothetical protein / 3
1591 / - / hypothetical protein / 3
330 / lemA / putative cytoplasmic membrane protein / 3
1364 / dnaX / DNA polymerase III subunits gamma tau / 3
2113 / - / hypothetical protein / 3
432 / - / hypothetical protein / 3
190 / - / hypothetical protein / 3
1282 / pyk / putative pyruvate kinase / 3
1889 / fba / putative fructose-bisphosphate aldolase / 3
274 / plr / glyceraldehyde-3-phosphate dehydrogenase, plasmin receptor / 3
2190 / sdhA / putative L-serine dehydratase alpha subunit / 3
630 / agaW / putative PTS dependent N-acetyl-galactosamine-IIC component / 3
267 / cbf / putative CMP-binding factor / 3
890 / deoB / putative phosphopentomutase / 3
1850 / - / putative esterase / 3
943 / - / hypothetical protein / 3
2097 / - / putative PTS system enzyme II / 3
652 / - / hypothetical protein / 3
1987 / - / hypothetical protein / 3
- / putative transposase - IS1548 / 3
2027 / - / putative two-component response regulator / 3
1815 / scrA / putative sucrose-specific PTS permease, enzyme II / 3
2032 / - / putative ATP-binding cassette transporter-like protein / 3
1606 / - / putative RNA methyltransferase / 3
1159 / hlyIII / putative hemolysin III / 3
224 / hasC.2 / putative UDP-glucose pyrophosphorylase / 3
1107 / - / putative two-component sensor histidine kinase / 3
230 / - / putative ABC transporter (ATP-binding protein) / 3
1801 / isp2 / immunogenic secreted protein precursor homolog / 3
2066 / - / putative dipeptidase / 3
- / hypothetical protein / 3
1638 / atoD.1 / putative Acetyl-CoA:acetoacetyl-CoA transferase A subunit / 3
1990 / pabB / putative para-aminobenzoate synthetase / 3
1785 / recG / putative ATP-dependent DNA helicase / 3
1281 / sipC / putative signal peptidase I / 3
189 / - / hypothetical protein / 3
1312 / dltA / putative D-alanine-D-alanyl carrier protein ligase / 3
303 / - / putative transposase, IS1548 / 3
2026 / - / putative histidine kinase / 3
457 / - / putative cyclophilin-type protein / 3
458 / - / hypothetical protein / 3
740 / sagC / streptolysin S associated ORF / 3
738 / sagA / streptolysin S associated protein / 3
229 / - / putative ABC transporter, ATP-binding protein / 3
556 / - / hypothetical protein / 3
1674 / - / putative ABC transporter (ATP-binding protein) / 3
447 / pfs / putative MTA SAH nucleosidase (5 -methylthioadenosine S-adenosylhomocysteine nucleosidase) / 3
940 / - / hypothetical protein / 3
739 / sagB / streptolysin S associated ORF / 3
1128 / pta / putative phosphotransacetylase / 3
1058 / - / putative phosphotransferase system (PTS), enzyme II component B / 3
1175 / - / hypothetical protein / 3
1581 / - / hypothetical protein / 3
1151 / ldh / putative L-lactate dehydrogenase / 3
1837 / mutS2 / putative DNA mismatch repair protein / 3
2034 / - / conversed hypothetical protein / 3
1870 / - / putative transcriptional regulator (GntR family) / 3
2099 / - / putative transcriptional regulator (GntR family) / 3
448 / - / hypothetical protein / 3
1022 / estA / putative tributyrin esterase / 3
1947 / - / putative transaldolase / 3
100 / - / putative DNA binding protein / 3
894 / deoD2 / putative purine nucleoside phosphorylase / 3
1840 / - / hypothetical protei / 3
3 / dnaN / beta subunit of DNA polymerase III / 3
414 / lctO / putative lactate oxidase / 3
1856 / norA / putative antibiotic resistance protein NorA / 3
160 / purA / putative adenylosuccinate synthetase / 3
1704 / lacD.1 / putative tagatose 1,6-diphosphate aldolase / 3
1087 / srtG / conserved hypothetical protein - lantibiotics associated / 3
1796 / - / hypothetical protein / 3
199 / - / conserved hypothetical protein, IS861 associated / 3
188 / vlg / regulatory protein / 3
459 / - / hypothetical protein / 3
1162 / rnh / putative ribonuclease HII / 3
1765 / - / putative D,D-carboxypeptidase / 3
654 / - / hypothetical protein / 3
1878 / - / putative transcriptional regulator / 3
1362 / birA / putative biotin operon repressor / 3
1670 / proA / putative gamma-glutamyl phosphate reductase / 3
544 / - / hypothetical protein / 3
444 / - / hypothetical protein / 3
2131 / - / hypothetical protein / 3
1283 / pfk / putative 6-phosphofructokinase / 3
2133 / - / hypothetical protein / 3
2132 / - / hypothetical protein / 3
1777 / codY / putative transcriptional pleiotropic repressor / 3
201 / - / hypothetical protein / 3
919 / - / hypothetical protein / 3
2033 / - / hypothetical protein / 3
112 / proC / putative pyrroline carboxylate reductase / 3
1717 / copY / putative negative transcriptional regulator - cpooer transport operon / 3
1730 / hit / putative cell-cycle regulation histidine triad (HIT) protein / 3
446 / - / hypothetical protein / 3
501 / - / putative multi-drug resistance efflux pump / 3
1580 / - / putative acetate kinase / 3
1582 / - / hypothetical protein / 3
2031 / - / putative ABC transporter (ATP-binding protein) / 3
1637 / atoB / putative acetyl-CoA:acetyltransferase / 3
115 / pepA / putative glutamyl-aminopeptidase / 3
1131 / - / hypothetical protein / 3
1810 / pmi / putative mannose-6-phosphate isomerase / 3
2116 / recA / recombination protein / 3
1805 / secA / putative preprotein translocase binding subunit (ATPase) / 3
2114 / - / hypothetical protein / 3
1818 / nusB / putative transcriptional terminator / 3
1386 / - / putative transcriptional regulator protein / 3
2117 / cinA / putative competence-damage protein / 3
1867 / deoC / putative deoxyribose-phosphate aldolase / 3
453 / mtsA / metal binding protein of ABC transporter (lipoprotein) / 3
1100 / folK / hydroxymethylpterin pyrophosphokinase / 3
175 / - / hypothetical protein / 3
1574 / - / putative transposase - IS1548 / 3
611 / tufA / putative translation elongation factor EF-Tu / 3
705 / - / hypothetical protein / 3
1995 / flaR / topology modulator / 3
1980 / - / hypothetical protein / 3
1084 / srtT / ABC transporter (ATP binding) - lantibiotic associated / 3
1177 / - / putative methylmalonyl-CoA decarboxylase, beta-subunit / 3
946 / - / putative P1-type antirepressor - phage associated / 3
1833 / mutY / putative A G-specific adenine glycosylase / 3
2148 / mutS / putative DNA mismatch repair protein / 3
1836 / - / hypothetical protein / 3
431 / - / hypothetical protein / 3
814 / folC.2 / putative folyl-polyglutamate synthetase / 3
741 / - / hypothetical protein / 3
1304 / amyB / putative cyclomaltodextrinase / 3
388 / murE / putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate ligase / 3
1302 / amyA / putative cyclomaltodextrin glucanotransferase / 3
1731 / - / hypothetical protein / 3
2005 / - / hypothetical protein / 3
1823 / comEB / putative late competence protein required for DNA binding / 3
1798 / - / hypothetical protein sharing similarity with several eukaryotic proteins / 3
1672 / proB / putative gamma-glutamyl kinase / 3
1639 / atoA / putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit / 3
2184 / yybT / hypothetical protein / 3
2089 / hutH / putative histidine ammonia-lyase / 3
2093 / tsf / putative elongation factor TS / 3
988 / - / hypothetical protein / 3
1106 / - / putative two-component response regulator / 3
1877 / glnA / putative glutamine synthetase / 3
2092 / rpsB / 30S ribosomal protein S2 / 3
545 / - / hypothetical protein / 3
1824 / pepP / putative aminopeptidase P; XAA-pro aminopeptidase / 3
273 / fus / translation elongation factor G, EF-G / 3
2174 / - / hypothetical protein / 3
1399 / nagB / putative N-acetylglucosamine-6-phosphate isomerase / 3
1492 / - / hypothetical protein / 3
1899 / - / hypothetical protein / 3
555 / - / putative portal protein - phage associated / 3
1619 / - / putative polyribonucleotide nucleotidyltransferase (general stress protein) / 3
898 / cpsY / putative transcriptional regulator / 2
1795 / - / putative ABC transporter (periplasmic binding protein) / 2
575 / - / hypothetical protein / 2
228 / - / hypothetical protein / 2
1973 / dexB / dextran glucosidase / 2
1596 / - / putative transcriptional regulator / 2
1841 / - / putative ribonuclease HIII / 2
254 / - / sugar transport system (permease) / 2
498 / - / hypothetical protein / 2
2087 / - / hypothetical protein / 2
1858 / pepXP / putative X-Pro dipeptidyl-peptidase IV / 2
1176 / - / putative methylmalonyl-CoA decarboxylase, gamma-subunit / 2
2140 / - / hypothetical protein / 2
643 / prfB / putative peptide chain release factor 2 / 2
2149 / - / hypothetical protein / 2
1952 / - / hypothetical protein / 2
576 / - / hypothetical protein / 2
212 / speG / exotoxin G precursor / 2
629 / agaD / putative PTS dependent galactosamine IID component / 2
1113 / - / putative acid phosphatase (class B) / 2
40 / - / hypothetical protein / 2
2053 / - / putative transcriptional regulator / 2
2216 / htrA / putative serine protease / 2
1723 / - / hypothetical protein / 2
631 / agaV / putative PTS dependent N-acetyl-galactosamine-IIB component / 2
899 / - / hypothetical protein / 2
1365 / - / hypothetical protein / 2
1311 / dltB / putative integral membrane protein / 2
781 / dnaG / putative DNA primase / 2
1721 / infB / putative initiation factor 2 / 2
6 / - / putative GTP-binding protein / 2
1034 / - / hypothetical protein / 2
1434 / - / putative heavy metal-transporting ATPase / 2
782 / rpoD / putative RNA polymerase sigma 42 protein / 2
1532 / - / hypothetical protein / 2
172 / metB / putative cystathionine beta-lyase / 2
142 / - / butyrate-acetoacetate CoA-transferase, beta subunit / 2
2084 / - / putative serine cycle enzyme / 2
2085 / fhs.2 / putative formate-tetrahydrofolate ligase / 2
1764 / - / putative N-acetyl-muramidase / 2
715 / - / putative transcriptional regulator (GntR family) / 2
2045 / - / protein low temperature requirement C / 2
1251 / truB / putative tRNA pseudouridine 55 synthase / 2
1625 / - / putative protein kinase / 2
2150 / ahrC / putative arginine repressor / 2
1648 / recU / putative recombination protein U / 2
1257 / - / putative ABC transporter (ATP-binding protein) / 2
1493 / - / hypothetical protein / 2
1827 / - / putative divalent cation transport protein / 2
1371 / gapN / putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase / 2
497 / fpg / putative formamidopyrimidine-DNA glycosylase / 2
1724 / nusA / transcription termination-antitermination factor / 2
1821 / efp / putative translation elongation factor EF-P / 2
874 / - / putative two-component response regulator / 2
952 / - / hypothetical protein / 2
1429 / gpmA / putative phosphoglycerate mutase / 2
1024 / - / hypothetical protein / 2
1158 / - / hypothetical protein / 2
1994 / pai1 / pai1 protein (theoretical repressor) / 2
1641 / - / hypothetical protein / 2
601 / - / putative endolysin, phage associated / 2
141 / atoD.2 / putative acetyl-CoA:acetoacetyl-CoA transferase alpha subunit / 2
1299 / malD / putative maltodextrin transport system permease / 2
1900 / thiD / putative phosphomethylpyrimidine kinase / 2
527 / - / hypothetical protein / 2
645 / ftsX / putative cell-division protein / 2
35 / abiR / possible abortive infection phage resistance protein / 2
1373 / ptsH / putative phosphotransferase system phosphohistidine-containing protein / 2
1060 / - / putative phosphotransferase system (PTS), enzyme II component D / 2
2054 / fucR / putative transcriptional regulator / 2
1626 / pppL / putative phosphoprotein phosphatase / 2
317 / - / hypothetical protein / 2
174 / - / hypothetical protein / 2
41 / - / putative acyltransferase / 2
215 / pgi / glucose-6-phosphate isomerase / 2
1250 / mreA / putative macrolide-efflux protein / 2
1651 / pepC / putative cysteine aminopeptidase C / 2
1605 / - / putative two-component responsible histidine kinase / 2
7 / pth / putative peptidyl-tRNA hydrolase / 2
1548 / - / hypothetical protein / 2
180 / - / hypothetical protein / 2
1986 / - / putative PTS system, enzyme II, A component / 2
732 / - / hypothetical protein / 2
1924 / lacR.2 / putative lactose phosphotransferase system repressor protein / 2
176 / - / hypothetical protein / 2
163 / - / putative ABC transporter (lipoprotein) / 2
742 / - / hypothetical protein / 2
2183 / rplI / 50S ribosomal protein L9 / 2
821 / - / hypothetical protein / 2
285 / - / putative ABC transporter (ATP-binding protein) / 2
1901 / truA / putative tRNA pseudouridine synthase A (pseudouridylate synthase I) / 2
1556 / - / putative two-component response regulator / 2
815 / - / hypothetical protein / 2
1820 / - / hypothetical protein / 2
1359 / metK / S-adenosylmethionine synthetase / 2
1680 / - / putative transcriptional regulatory protein / 2
644 / ftsE / putative cell-division ATP-binding protein / 2
1489 / hlpA / histone-like DNA-binding protein / 2
1503 / - / putative phosphomannomutase / 2
855 / - / putative fructose-specific enzyme II, PTS system BC component / 2
373 / ypaA / hypothetical protein / 2
1768 / - / hypothetical protein / 2
875 / - / putative two-component sensory transduction histidine kinase / 2
804 / infC / putative translation initiation factor 3 (IF3) / 2
1675 / - / hypothetical protein / 2
1770 / gatB / putative Glu-tRNAGln amidotransferase subunit B / 2
613 / tpi / putative triosephosphate isomerase / 2
528 / vicR / two-component response regulator / 2
1999 / - / hypothetical protein / 2
1793 / - / putative ABC transporter (ATP-binding protein) / 2
460 / rplK / 50S ribosomal protein L11 / 2
733 / - / hypothetical protein / 2
779 / rpsU / 30S ribosomal protein S21 / 2
2188 / - / putative tRNA-(5-methylaminomethyl-2-thiouridylate) / 2
1691 / - / hypothetical protein / 2
1903 / - / hypothetical protein / 2
1842 / spi / putative signal peptidase I / 2
326 / - / hypothetical protein / 2
819 / rplU / 50S ribosomal protein L21 / 2
1310 / dltC / putative D-alanyl carrier protein / 2
2052 / - / putative PTS system, enzyme III / 2
1174 / - / putative transcarboxylase subunit / 2
2082 / hutU / putative urocanate hydratase / 2
982 / - / putative structural protein - phage associated / 2
1180 / - / putative Mg2+ citrate complex transporter / 2
2147 / - / hypothetical protein / 2
1722 / - / putative ribosomal protein / 2
1642 / luxS / autoinducer-2 production protein / 2
1491 / - / hypothetical protein / 2
713 / pepD / putative dipeptidase / 2
1385 / - / hypothetical protein / 2
2189 / sdhB / putative L-serine dehydratase beta subunit / 2
1981 / relA / (p)ppGpp synthetase / 2
2152 / - / hypothetical protein / 2
1640 / - / putative oxidoreductase / 2
1294 / malX / putative maltose maltodextrin-binding protein / 2
2156 / aspS / putative aspartyl-tRNA synthetase / 2
1122 / - / putative iron-sulfur cofactor synthesis protein / 2
2096 / dexS / putative dextran glucosidase / 2
422 / metS / putative methionyl-tRNA synthetase / -2
1411 / - / hypothetical protein / -2
295 / oppC / oligopeptidepermease / -2
600 / - / hypothetical protein / -2
1632 / gmk / putative guanylate kinase / -2
824 / cpsY / putative capsular polysaccharide biosynthesis protein / -2
1351 / aroK / putative shikimate kinase / -2
729 / yueI / hypothetical protein / -2
339 / - / hypothetical protein / -2
371 / - / putative rRNA methylase / -2
1575 / - / hypothetical protein / -2
2002 / dppC / transmembrane transport protein / -2
726 / - / hypothetical protein / -2
650 / aspC / putative aspartate aminotransferase / -2
4 / - / hypothetical protein / -2
1658 / - / putative amino acid ABC transproter (permease protein) / -2
1941 / cysS / putative cysteinyl-tRNA synthetase / -2
294 / oppB / oligopeptidepermease / -2
1115 / - / hypothetical protein / -2
337 / csrS / putative sensory transduction histidine kinase / -2
1213 / fhs.1 / putative formate-tetrahydrofolate ligase / -2
1647 / - / hypothetical protein / -2
835 / carB / putative carbamoylphosphate synthetase / -2
832 / pyrB / putative aspartate transcarbamoylase / -2
171 / - / hypothetical protein / -2
1036 / - / hypothetical protein / -2
1421 / ddlA / putative D-ala,D-ala ligase / -2
918 / - / putative exfoliative toxin / -2
148 / ntpI / V-type Na+ -ATPase subunit I / -2
1864 / dnaQ / putative DNA polymerase III epsilon subunit / -2
469 / - / putative 42 kDa protein / -2
378 / hlyX / putative hemolysin / -2
1983 / sclA / collagen-like surface protein / -2
1209 / pdxK / putative pyridoxal kinase / -2
830 / pyrR / putative pyrimidine regulatory protein / -2
235 / - / putative dUTPase, phage associated / -2
797 / - / hypothetical protein / -2
900 / pyrF / putative orotidine-5 -decarboxylase PyrF / -2
1049 / - / hypothetical protein / -2
2207 / trsA / putative tryptophanyl-tRNA synthetase / -2
1630 / - / hypothetical protein / -2
296 / oppD / oligopeptidepermease (ATP-binding protein) / -2
2165 / - / hypothetical protein / -2
1127 / - / hypothetical protein / -2
609 / ftsW / putative cell division protein / -2
1274 / - / putative amino acid ABC transporter, periplasmic amino acid-binding protein / -2
2003 / dppD / ATPase protein / -2
168 / - / hypothetical protein / -2
768 / pheS / putative phenylalanyl-tRNA synthetase (alpha subunit) / -2
2198 / - / hypothetical protein / -2
246 / rnpA / putative ribonuclease P protein component / -2
1047 / - / hypothetical protein / -2
1508 / - / hypothetical protein / -2
794 / - / putative glycosyl transferase / -2
507 / - / hypothetical protein / -2
96 / TyrS / putative tyrosine-tRNA ligase / -2
580 / - / hypothetical protein / -2
1085 / srtF / ABC transporter (ATP-binding) - lantibiotic associated / -2
1275 / - / putative amino acid ABC transporter (ATP-binding protein) / -3
2001 / dppB / transmembrane transport protein / -3
1401 / - / hypothetical protein / -3
1198 / - / putative repressor protein / -3
110 / - / hypothetical protein / -3
309 / - / hypothetical protein / -3
599 / - / putative transcription regulator / -3
1233 / coaA / putative pantothenate kinase / -3
1571 / - / hypothetical protein / -3
1854 / glpF.2 / putative glycerol uptake facilitator protein / -3
108 / ythI / hypothetical protein / -3
1315 / - / hypothetical protein / -3
510 / yfhN / putative sugar transferase / -3
1234 / rpsT / 30S ribosomal protein S20 / -3
1572 / - / hypothetical protein / -3
2199 / - / hypothetical protein / -3
1942 / - / hypothetical protein / -3
844 / - / hypothetical protein / -3
338 / - / hypothetical protein / -3
1733 / - / putative transcription regulator / -3
1940 / - / hypothetical protein / -3
145 / - / hypothetical protein / -3
2004 / dppE / ATPase protein / -3
2162 / cadD / putative cadmium resistance protein / -3
1502 / folD / putative bifunctional methylenetetrahydrofolate dehydrogenase methenyltetrahydrofolate cyclohydrolase / -3
2144 / - / hypothetical protein / -3
385 / fhuD / ferrichrome ABC transporter (ferrichrome-binding protein) / -3
1155 / - / hypothetical protein / -3
1046 / - / hypothetical protein / -3
1140 / tdk2 / putative thymidine kinase / -3
2211 / - / hypothetical protein / -3
308 / - / hypothetical protein / -3
1138 / - / putative thiamine biosynthesis lipoprotein precursor / -3
1629 / priA / putative primosomal replication factor Y / -3
722 / - / hypothetical protein / -3
887 / - / hypothetical protein / -3
315 / - / hypothetical protein / -3
84 / - / hypothetical protein / -3
796 / - / hypothetical protein / -3
793 / - / hypothetical protein / -3
1736 / - / hypothetical protein / -3
1368 / udk / putative uridine kinase / -3
1201 / ylxM / putative DNA-binding protein / -3
798 / - / hypothetical protein / -3
1276 / - / putative amino acid ABC transporter (permease protein) / -3
464 / - / hypothetical protein / -3
833 / carA / putative carbamoyl phosphate synthetase small subunit / -3
310 / - / hypothetical protein / -3
466 / msrA.2 / putative peptide methionine sulfoxide reductase / -3
383 / fhuG / putative ferrichrome ABC transporter (permease) / -3
1277 / - / hypothetical protein / -3
508 / - / hypothetical protein / -3
1124 / - / hypothetical protein / -3
467 / yozE / hypothetical protein / -4
324 / - / putative sodium dicarboxylate symporter / -4
843 / - / hypothetical protein / -4
329 / gidB / putative glucose-inhibited division protein / -4
831 / pyrP / putative uracil permease / -4
1414 / kup / putative cation (K+) transport protein / -4
622 / - / hypothetical protein / -4
1202 / - / putative transcription regulator, GntR family / -4
1039 / - / hypothetical protein / -4
1367 / - / hypothetical protein / -4
1695 / - / hypothetical protein / -4
393 / - / hypothetical protein / -4
117 / - / hypothetical protein / -4
2195 / - / ABC transporter (ATP-binding protein) / -4
1741 / - / hypothetical protein / -4
1340 / - / hypothetical protein / -4
2197 / - / hypothetical protein / -4
2196 / pgsA / phosphatidylglycerophosphate synthase / -4
930 / - / hypothetical protein / -4
1071 / thdF / putative thiophene degradation protein F / -4
2194 / - / putative ABC transporter (ATP-binding protein) / -4
849 / trmD / putative tRNA (guanine-N1)-methyltransferase / -4
2209 / - / hypothetical protein / -4
384 / fhuB.1 / putative ferrichrome ABC transporter (permease) / -4
392 / upp / putative uracil phosphoribosyltransferase / -4
1734 / - / hypothetical protein / -4
421 / yoaK / hypothetical protein / -5
305 / - / hypothetical protein / -5
1208 / - / hypothetical protein / -5
2163 / cadC / putative cadmium efflux system accessory / -5
847 / - / putative 16S rRNA processing protein / -5
1203 / - / hypothetical protein / -5
306 / - / hypothetical protein / -5
846 / - / hypothetical protein / -5
2193 / - / hypothetical protein / -5
2191 / - / hypothetical protein / -5
1137 / - / putative purine permease / -5
307 / - / hypothetical protein / -5
1735 / - / hypothetical protein / -6
1206 / - / putative ABC transporter (ATP-binding protein) / -6
312 / - / hypothetical protein / -6
1391 / - / putative methyltransferase / -6
850 / - / putative thioredoxin reductase / -6
314 / - / hypothetical protein / -7
912 / bdrA8 / hypothetical protein / -7
1114 / - / hypothetical protein / -7
1136 / xpt / putative xanthine phosphoribosyltransferase / -7
95 / - / putative histidine triad (HIT) protein / -7
870 / fms / putative polypeptide deformylase / -7
386 / fhuA / putative ferrichrome ABC transporter (ATP-binding protein) / -7
1139 / - / putative 4-oxalocrotonate tautomerase / -8
1270 / - / putative amino acid symporter / -8
1506 / - / putative amino acid ABC transporter (ATP-binding protein) / -11
1507 / - / putative amino acid ABC transporter (permease protein) / -11
1205 / - / putative antimicrobial resistance factor / -15
323 / braB / putative branched-chain amino acid transport protein / -15
a SPy numbers are based on annotation of the SF370 S. pyogenes strain complete genome (Ferretti, 2001).