Department of Morphology of Microorganisms and Electron Microscopy

DEPARTMENT OF MORPHOLOGY OF MICROORGANISMS AND ELECTRON MICROSCOPY

Cherepova, N., Spasova, D., Radoevska, S. 2001. Ultrastructural localization of succinate dehydrogenase in some bacteria after treatment with Lubrol W1. Microbios104, 49-54.

Stoitsova, S., Boteva, R., Doyle, R., 2003. Binding of hydrophobic ligands by Pseudomonas aeruginosa PA-I lectin. Biochim. Biophys. Acta1619, 213-219.

Stoitsova, S., Ivanova, R., Dimova, I., 2004. Lectin-binding epitopes at the surface of Escerichia coli K-12: examination by electron microscopy with special reference to the presence of a colonic acid-loke polymer. J. Basic Microbiol. 44, 296-304.

Bivolarska, M., Velinov, T., Stoitsova, S. 2006. Guided-wave and ellipsometric imaging of supported cells. Journal of Microscopy224, 42-248.

Spasova, D., Aleksieva, P., Nacheva, L., Radoevska, S., 2007. Ultracytochemical localization of acid phosphatase in Humicola lutea conidia and mycelia. Z. Naturforsh. 62C , 65-69.

Sotirova, A., Spasova, D., Vasileva-Tonkova, E., Galabova, D., 2007. Effects of rhamnolipid-biosurfactant on cell surface of Pseudomonas aeruginosa. Microbiol. Res. Doi: 10.1016/j.micres.2007.01005.2007

DEPARTMENT OF MICROBIAL BIOCHEMISTRY

Christova, N., B. Tuleva, B. Damyanova. Enhanced hydrocarbon biodegradation by a newly isolated Bacillus subtilis strain. Z. Naturforsch., 2004, 59c, 205-208.

Mutafov, S., B. Angelova, H.-P. Schmauder, T. Avramova, L. Boyadjieva. Stoichiometry of microbial continuous-flow purification of toluene contaminated air. Applied Microbiol. Biotechnol., 2004, 65, 228-234.

Abrashev, I., G. Dulgerova, P. Dolashka-Angelova, W. Voelter. Purification and characterization of a novel sialidase from a strain of Arthrobacter nicotiane. J. Biochem., 2005, 137, 365-371.

Abrashev, I., P. Orozova. E. rhusiopathiae neuraminidase and its role in pathogenicity. Z. Naturforsch., 2006, 61c, 434-438.

Sotirova, A., Spasova, D., Galabova, D., Karpenko, E., Shulga, A. Rhamnolipid–biosurfactant permeabilizing effects on Gram-positive and Gram-negative bacterial strains. Curr Microbiol. 2008, DOI 10.1007/s00284-008-9139-3

Angelova B., Avramova T., Stefanova L., Mutafov S. Temperature effect on bacterial azo bond reduction kinetics: an Athenius plot analysis. Biodegradation, 2007, [On line first]

Tuleva B., Christova N., Cohen R., Stoev G., Stoineva I. Production and structural elucidation of trehalose tetraesters (biosurfactants) from a novel alkanotrophic Rhodococcus wratislaviensis strain. 2008, doi:10.1111/j.1365-2672.2007.03680.x

Avramova T., Sotirova A., Galabova D., Karpenko E. Effect of Triton X-100 and rhamnolipid PS-17 on the mineralization of phenanthrene byPseudomonas sp. cells.International Biodeterioration & Biodegradation, 2008 (in press).

DEPARTMENT OF MICROBIAL GENETICS

Alexieva, Z., Gerginova, M., Zlateva, P., Peneva, N. (2004): Comparison of growth kinetics and phenol metabolizing enzymes of Trichosporon cutaneum R57 and mutants with modified degradation abilities.Enz. Microb. Technol.34 (3-4), 242-247

Aleksieva, Z., Ivanova, D., Godjevargova, T., Atanasov, B. (2002): Degradation of some phenol derivatives by Trichosporon cutaneum R57. Proc. Biochem.37 (11), 1215-1219

Gerginova, M., Manasiev, J., Shivarova, N., Alexieva, Z. (2007): Influence of various phenolic compounds on phenol hydroxylase activity of a Trichosporon cutaneum strain.Zeitschrift fur Naturforschung - Section C Journal of Biosciences62 (1-2), 83-86

Lyutskanova, D., Stoilova-Disheva, M., Peltekova, V. (2005): Increase in tylosin production by a commercial strain of Streptomyces fradiae.Appl. Biochem. Microbiol.41 (2), 165-168

Lahtchev, K., Semenova, V., Tolstorukov, I., VanderKlei, I., Veenhuis, M. (2002): Isolation and properties of genetically defined strains of the methylotrophic yeast Hansenula polymorpha CBS4732.Archives of Microbiology177 (2), 150-158

Stoyancheva, G., Danova, S., Boudakov, I. (2006): Molecular identification of vaginal lactobacilli isolated from Bulgarian women.Antonie van Leeuwenhoek 90 (3), 201-210

Petrova, P., Gouliamova, D. (2006): Rapid screening of plasmid-encoded small hsp-genes in Streptococcus thermophilus.Current Microbiology53 (5), 422-427

Petrova, P., Miteva, V., Ruiz-Masó, J.A., Del Solar, G. (2003): Structural and functional analysis of pt38, a 2.9 kb plasmid of Streptococcus thermophilus yogurt strain.Plasmid50 (3), 176-189

Dimitonova, S., Danova, S., Serkedjieva, J., Bakalov, B. (2007): Antimicrobial activity and protective properties of vaginal lactobacilli from healthy Bulgarian women.Anaerobe 13 (5-6), 178-184

Danova, S., Stoyancheva, G., Manasiev, Y., Miteva, V. (2005): Development and application of random DIG-labelled probes based on total genomic Lactobacillus DNA.World J. Microbiol. Biotechnol.21 (6-7), 835-842

DEPARTMENT OF MICROBIAL BIOSYNTHESIS AND BIOTECHNOLOGY

DEPARTMENT OF MICROBIAL ECOLOGY

Todorova, D., Nedeva, D., Abrashev, R., Tsekova, K. Cd (II) stress response during the growth of Aspergillus niger B 77. Journal of AppliedMicrobiology, published article online: 11-Sep-2007.

Tsekova, K., Ianis, M., Dencheva, V., Ganeva, S. Biosorption of Binary Mixtures of Cooper and Cobalt by Penicillium brevicompactum.Zeitschrift fuer Naturforschung 62, 261-264, 2007.

Tzvetkova, I., Dalgalarrondo, M., Danova, S., Iliev, I., Haertlй, Th., Ivanova, I., Chobert J.-M. Hydrolysis of major dairy proteins by lactic acidbacteria from Bulgarian yogurts. Journal of Food Biochemistry 31 (5), 680-702, 2007.63

DEPARTMENT OF MYCOLOGY

Angelova, M., P. Dolashka-Angelova, E. Ivanova, J. Serkedjieva, L. Slokoska, S. Pashova, R. Toshkova, S. Vassilev, I. Simeonov, H-J. Hartmann, S. Stoeva, U. Weser, W.Voelter. A novel glycosylated Cu/Zn-containing superoxide dismutase: production and potential therapeutic effect. Microbiology (UK), 2001, 147, 1641-1650.

Stefanov R., Angelova, M., Stefanova Z., Subev M., Dolashka P., Voelter W., Zachariev Z. Cu/Zn-Superoxide dismutase from the fungal strain Humicola lutea 103 improves ram spermatozoa functions during liquid storage. Andrologia, 2004, 2, 51-56

Dolashka-Angelova P., Stevanovic S., Dolashki A., Angelova M., Pashova S., Krumova E., Serkejieva J., Zacharieva S., Voelter W. Structural and functional analyses of glycosylated Cu/Zn-SOD from the fungal strain Humicola lutea 103, cultivated in copper stress conditions. Biochem. Biophys Res Com, 2004, 317, 1006-1016

Angelova M., Pashova S., Spasova B., Vassilev S., Slokoska S. Oxidative stress response of filamentous fungi induced by hydrogen peroxide and paraquat. Mycol. Res. 2005, 109 (2), 150-158

Sokmen M., M. Angelova, E. Krumov, S. Pashov,S. Ivanchev, A. Sokmen, J. Serkedjieva. In vitro antioxidant activity of polyphenol extracts with antiviral properties from Geranium sanguineum L. Life Sci. 2005, 76, 2981-2993.

Abrashev, R., P. Dolashka, R. Christova, L. Stefanova, M. Angelova Role of antioxidant enzymes in survival of conidiospores of Aspergillus niger 26 under conditions of temperature stress. J. Appl. Microbiol. 2005, 99, 902-909.

Elena Kovacheva, Milen Georgiev, Svetlana Pashova, M.Angelova, and Mladenka Ilieva Radical Quenching by Rosmarinic Acid from Lavandula vera MM Cell Culture Z. Naturforsch. 2006, 61c, 517-521.

Krumova, E., Dolashka-Angelova, P., Pashova, S., Stefanova, L., Van Beeumen, J.,Vassilev, S., M. Angelova (2007) Improved production by fed-batch cultivation and some properties of Cu/Zn-superoxide dismutase from the fungal strain Humicola lutea 103. EnzymeMicrobTechnol40, 4,5 524-532

Gocheva, Y., Krumova, E., Slokoska, L., Miteva, J., Angelova,M. Cell response of Antarctic and temperate strains of Penicillium spp. to different growth temperature. Mycol. Res. 2006, 110, 1347-1354

Krumova, E., Dolashki, A., pashova, S., Dolashka-Angelova, P., Stevanovic, S., Hristova, R., Stefanova, L., Voelter, W., M. Angelova.Unusual location and characterization of Cu/Zn-containing superoxide dismutase from filamentous fungus Humicola lutea.Arch. Microbiol. 2007, 189, 121-130

DEPARTMENT OF EXTREMOPHILIC BACTERIA

Groudieva, T., M. Kambourova, H. Yusef, M. Royter, R. Grote, H. Trinks, G. Antranikian. Diversity and cold-active hydrolytic enzymes of culturable bacteria associated with Arctic sea ice, Spitzbergen. Extremophiles (2004),v.8, No 6, 475-488.

Kabaivanova L.,Dobreva, E.,Dimitrov, P., E.Emanuilova Immobiliztion of cells with nitrilase activity fron a theremophilic bacterial strain J. Ind. Microbiol.Biotechnol.(2005) , 32, 7-11.

Derekova, A., Sjoholm, C., Mandeva, R., Michailova, L., Kambourova, M. (2006). Biosynthesis of a thermostable gellan lyase by newly isolated and characterized strain of Geobacillus stearothermophilus 98. Extremophiles v. 10, No 4, 321-326.

Tonkova A. Microbial starch-converting enzymes of the α-amylase family (2006). In: Microbial Biotechnology in Horticulture (Eds.:Ramesh C. Ray and Owen P. Ward) Science Publishers, Enfield, New Hampshire, USA, vol. 1, pp. 421-472.

Derekova, A., Sjøholm, C., Mandeva, R., Kambourova, M. (2007). Anoxybacillus rupiensis sp. nov., a novel thermophilic bacterium isolated from Rupi basin (Bulgaria). Extremophiles v. 11, No 4, 577-583.

Kambourova, M., Mandeva, R., Fiume, I., Maurelli, L., Rossi, M., Morana, A. (2007). Hydrolysis of xylan at high temperature by co-action of the xylanase from Anoxybacillus flavithermus BC and the beta-xylosidase/alpha-arabinosidase from Sulfolobus solfataricus Oalpha. J. Appl. Microbiol. Vol. 102, 1586 - 1593.

Safarikova M, Atanasova N, Ivanova V, Weyda F, Tonkova A. (2007). Cyclodextrin glucanotransferase synthesis by semicontinuous cultivation of magnetic biocatalysts from cells of Bacillus circulans ATCC 21783. Process Biochemistry, 42, 1454-1450.

Samuneva, B., Djambaski, P., Kashchieva, E., Chernev, G., Kabaivanova, L., Emanuilova, E., Salvado, I.M.M., FernandesM.H.V., Wu, A., (2007) Sol-gelsynthesisandstructureofsilicahybridbiomaterials . J. Non-CrystallineSolids, 354/2-9, 733-740

AtanassovaM., DerekovaA., MandevaR., SjøholmC., KambourovaM. (2008). Anoxybacllus bogrovensis sp. nov., a novel thermophilic bacterium isolated from Dolni Bogrov’s hot spring, Bulgaria. Int. J. Syst. Evol. Micr. (in press).

Atanasova N., Petrova P., Ivanova V., Yankov D., Vassileva A., Tonkova A. (2008) Isolation of novel alkaliphilic Bacillus strains for cyclodextrin glucanotransferase production. Applied Biochemistry and Biotechnology, (in press).

DEPARTMENT OF PATHOGENIC BACTERIA

Najdenski, H., Golkocheva, E.,Kussovski, V., Ivanova, E., Manov,V., IlievM., Vesselinova, A., Bengoechea, J.A., Skurnik,M. Experimental pig yersiniosis to assess attenuation of Yersinia enterocolitica O:8 mutant strains. FEMS Immunol. Med. Microbiol., 47, 425-435, 2006.

Mokrousov,I.,Jiao,W.W., Valcheva, V., Vyazovaya, A., Otten, T., Ly, H. M., Lan, N. N., Limeschenko, E., Markova, N.,Vyshnevskiy, B., Shen, A.D., NarvskayaO. RapidDetectionoftheMycobacteriumtuberculosisBeijinggenotypeanditsancientandmodernsublineagesbyIS6110-basedinversePCR. J. Clin. Microbiol., 44: 2851–2856, 2006.

Najdenski, H., M. Heyndrickx, L. Herman, W. Messens. Fla-DGGE analysis of Campylobacter jejuni and Campylobacter coli in cecal samples of broilers without cultivation. Vet. Microbiology, 2008, 127, 196-202

V. Valcheva, I. Mokrousov, N. Rastogi, O. Narvskaya, N. Markova. Molecular characterization of Mycobacterium tuberculosis isolates from different regions of Bulgaria.J.ClinicalMicrobiology, 2008, 46, 3, 1014-1018.

Bonovska, M., Tzvetkov,Y., Najdenski,H., Bachvarova,Y. PCRfordetectionofMycobacteriumtuberculosisinexperimentallyinfecteddogs. J. Vet. Med., 2005, 52(10), 5-8.

Bengoechea, J-A., Najdenski, H., Skurnik, M. Essential role of the lipopolysaccharide O-antigen status of Yersinia enterocolitica O:8 in virulence and in the outer membrane regulatory network. Mol. Microbiol., 2004, 52, 451-469.

Najdenski, H., Golkocheva, E., Vesselinova, A., Russmann, H. Comparison of the course of infection of virulent Yersinia enterocolitica serotype O:8 with an isogenic soda mutant in the peroral rabbit model. Int. J. Med. Microbiol., 2004, 294, 383-393.

Najdenski, H., Kussovski, V., Vesselinova, A. ExperimentalBurkholderiapseudomalleiinfectionofpigs. J. Vet. Med. B, 2004, 51,225-230.

Najdenski, H.,I. Iteman, E. Carniel. Efficient subtyping of pathogenic Yersinia enterocolitica by pulsed field gel electrophoresis. J. Clin. Microbiology, 32, 1994, 12, 2913-2920.

Najdenski H., Vesselinova A. Experimental mixed infection of rabbits with Yersinia enterocolitica and Listeria monocytogenes. J. Vet. Med. B, 2002, 49, 97-104.

DEPARTMENT OF VIROLOGY

DEPARTMENT OF IMMUNOLOGY

Ivanovska, N.D., Dimitrova, P., Luckett, J.C., Lonnen,R.,Wilhelm J., Schwaeble, W. and Stover, C.M. Properdin deficiency in murine models of non-septic shock. J Immunol. 2008, 180, (in press)

Dimitrov, J., Roumenina, L., Doltchinkova, V., Mihaylova, N., Desmazes, S.-L., Kaveri, S. and Vassilev.T. Antibodies use heme as a cofactor to extend their pathogen-eliminating activity and to acquire new effector functions. J.Biol.Chem., 2007, 282, 26696-26706.

Dimitrov J.D., Ivanovska, N.D., Lacroix-Desmazes, S., Doltchinkova, V.R., Kaveri, S.K. and Vassilev, T.L. Ferrous ions and reactive oxygen species increase antigen-binding and anti-inflammatory activities of immunoglobulin G. J.Biol.Chem., 2006, 281, 439-446.

Tchorbanov, A., Voynova, E., Mihaylova, N., Todorov, T., Nikolova, M., Yomtova, V., Chiang, B.-L. and Vassilev, T. Selective silencing of DNA-specific B lymphocytes delays lupus activity in MRL/lpr mice. Eur.J.Immunol., 2007, 37, 3587-3596.

Mihaylova, N., Voynova, E., Tchorbanov, A., Nikolova, M., Michova, A., Todorov, T., Srebreva, L., Taskov, H. and Vassilev, T.Selective silencing of disease-associated B-lymphocytes by chimeric molecules targeting their FcγRIIb receptor. Int.Immunol., 2008, 20, 165-175.

Dimitrov, J.D., Roumenina, L.T., Doltchinkova, V.R. and Vassilev, T.L. Iron ions and heme modulate the binding properties of complement subcomponent C1q and of immunoglobulins. Scand.J.Immunol., 2007, 65, 230-239.

Ivanovska, N., Tchorbanov, A., Prechl, J., Maximova, V., Voynova, E., Vassilev, T.L. Immunization with a DNA chimeric molecule encoding a hemagglutinin peptide and a scFv CD21-specific antibody fragment induces long-lasting IgM and CTL responses to influenza virus. Vaccine, 2006, 24,1830-1837.

Dimitrov, J.D. Lacroix-Desmazes, S., Kaveri, S.K., and Vassilev, T.L. Transition towards antigen-binding promiscuity of a monospecific antibody. Molec.Immunol., 2007, 44, 1864-1873

M. Remichkova, M. Yordanov and P. Dimitrova. Etoposide Attenuates Zymosan-Induced Shock in Mice. Inflammation. 2008 Feb;31(1):57-64.

Dimitrova P, Ivanovska N. Influence of leflunomide on gastrointestinal Candida albicans infection induced in naive and arthritic newborn mice. Int Immunopharmacol. 2006 Nov;6(11):1682-9.

Dimitrova P, Ivanovska N. Host resistance to Candida albicans infection of mice with collagen-induced arthritis treated with leflunomide. Res Microbiol. 2006 157(6):525-30.

Yordanov M, Dimitrova P, Patkar S, Falcocchio S, Xoxi E, Saso L, Ivanovska N.Ibogaine reduces organ colonization in murine systemic and gastrointestinal Candida albicans infections. J Med Microbiol. 2005 Jul;54(Pt 7):647-53.

Yordanov M, Dimitrova P, Danova S, Ivanovska N.Candida albicans double-stranded DNA can participate in the host defense against disseminated candidiasis. Microbes Infect. 2005 Feb;7(2):178-86.

Yordanov M, Tchorbanov A, Ivanovska N.Candida albicans cell-wall fraction exacerbates collagen-induced arthritis in mice. Scand J Immunol. 2005 Apr;61(4):301-

RESEARCH GROUP FOR MATHEMATICAL MODELING AND COMPUTER SCIENCES

Simeonov I., S. Stoyanov, V. Lubenova, Robust compensator control of aerobic continuous fermentation processes with state estimation, Archives of Control Sciences, Vol. 13, No 1, 2003, 5-18

SimeonovI., S. Stoyanov, Modelling and dynamic compensator control of the anaerobic digestion of organic wastes, Chem. Biochem.Eng.Q., 17 (4), 2003, 285-292

GalabovaD., I. Simeonov, D. Dalev, D. Karakashev, Research and optimization of the anaerobic digestion of organic wastes, Ecological Engineering and Environment Protection, 2, 2003, 37-43

Laroche B., I. Simeonov, Start-up of an anaerobic digester based an open loop flat control, Information Technologies and Control, 2005, 34-40

Karakashev D., D.Galabova, N.Fuchedjieva, I.Simeonov, Effect of electron acceptor conditions on the proteolytic activities of bacteria involved in anaerobic digestion, Comptes Rendus de l’Academie bulgare des Sciences, Tome 58, No 3, 2005, pp. 311-314

Simeonov I., I. Queinnec, Linearizing control of the anaerobic digestion, Control Engineering Practice,14, 2006, 799-810 (IF=0.797)

Simeonov I., N. Noykova, M. Gyllenberg, Identification and extremum seeking control of the anaerobic digestion of organic wastes, Cybernetics and information technologies, Vol. 7, No 2, 2007, pp. 73-84

Chamroo, A., Simeonov, I., Vasseur, C., Christov, N., Piecewise continuous control of a methane fermentation process. Studies in Informatics and Control, (in press).

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