Dear Colleague,

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As you’re likely aware, 10% of all cancer cases are thought to be inherited. For sarcomas in particular, the evidence for genetic risk factors continues to grow.

Knowing if an individual carries an underlying pathogenic genetic variant could help guide the treatment and management of sarcomas. Identification of a pathogenic variant also guides the testing and diagnoses of at-risk relatives and aids in the early detection and possible prevention of certain cancers.

I am reaching out to encourage you to refer sarcoma patients who meet the criteria below to our genetics department for an evaluation and, if warranted, genetic testing. I also want to make sure you know that I am available as a resource regarding the very latest research into the genes now associated with hereditary sarcoma. As a licensed, board-certified genetic counselor, I can provide the following guidance and support:

●  explain complex genetic concepts

●  analyze patients' family histories to understand disease risk

●  help patients and their families understand what their genetic test results mean

●  offer support throughout the testing process

●  review the most relevant and up to date publications and management guidelines

High-quality genetic testing for sarcoma is now accessible and affordable. These tests analyze many genes that are associated with a hereditary predisposition to the development of sarcoma. Listed below are some characteristics of patient types you should consider referring to us if they present to you in the clinic:

When to refer for genetic risk assessment

❏  Cancer diagnosis at a young age

❏  Individuals with personal/clinical history of sarcoma or other sarcoma-related tumors

❏  Individuals with familial history of sarcoma or other sarcoma-related tumors

If any of the above characteristics apply to your patient, {Personalized message: We suggest using this space to provide details on how to refer patients to you.}

Best regards,

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