Table A: Plasma glycerophospholipidsconcentrations of responders and non-responders pre- and post n-3 PUFA supplementation.

Responders (n=6) / Non-Responders(n=6) / P value
Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Delta (post- pre n-3 PUFAs)
PC aa C24:0 / 0.17±0.02 / 0.26±0.06 / NS / 0.22±0.06 / 0.26±0.06 / NS / NS / NS
PC aa C26:0 / NA / NA / NA / NA / NA / NA
PC aa C28:1 / 2.80±0.30 / 2.75±0.20 / NS / 3.01±0.25 / 3.12±0.25 / NS / NS / NS
PC aa C30:0 / 4.70±0.65 / 4.60±0.65 / NS / 3.92±0.39 / 4.86±0.66 / NS / NS / NS
PC aa C30:2 / 0.96±0.18 / 0.86±0.12 / NS / 0.53±0.08 / 1.23±0.13 / NS / NS / NS
PC aa C32:0 / 17.12±1.70 / 15.45±1.02 / NS / 17.13±1.24 / 19.43±2.59 / NS / NS / NS
PC aa C32:1 / 26.26±5.67 / 16.31±4.04 / 0.0333 / 22.93±4.30 / 21.65±5.29 / NS / NS / NS
PC aa C32:2 / 6.42±1.08 / 4.95±1.25 / NS / 5.15±0.35 / 6.30±0.71 / NS / NS / NS
PC aa C32:3 / 0.73±0.08 / 0.67±0.02 / NS / 0.90±0.18 / 0.74±0.10 / NS / NS / NS
PC aa C34:1 / 260.33±25.43 / 212.83±22.90 / 0.0014 / 284.83±35.73 / 264.00±25.11 / NS / NS / NS
PC aa C34:2 / 497.17±44.66 / 404.50±23.20 / NS / 609.00±66.3 / 458.17±33.91 / 0.0397 / NS / NS
PC aa C34:3 / 26.87±3.31 / 16.98±1.51 / 0.0081 / 27.77±4.74 / 22.35±4.15 / NS / NS / NS
PC aa C34:4 / 3.15±0.55 / 2.22±0.28 / 0.0286 / 2.13±0.44 / 2.15±0.21 / NS / NS / NS
PC aa C36:0 / 3.08±0.64 / 4.48±0.61 / NS / 4.88±1.79 / 4.91±1.12 / NS / NS / NS
PC aa C36:1 / 58.50±5.22 / 50.03±3.60 / NS / 55.57±10.23 / 70.60±7.73 / NS / NS / NS
PC aa C36:2 / 296.00±9.17 / 254.00±32.02 / NS / 322.17±51.01 / 265.50±22.64 / NS / NS / NS
PC aa C36:3 / 169.50±21.42 / 119.33±11.44 / 0.0283 / 173.83±15.56 / 132.88±13.77 / 0.0040 / NS / NS
PC aa C36:4 / 204.50±31.63 / 163.67±13.20 / NS / 229.67±29.84 / 187.83±20.31 / NS / NS / NS
PC aa C36:5 / 26.68±3.78 / 98.95±5.94 / <0.0001 / 24.05±4.50 / 90.07±15.08 / 0.0116 / NS / NS
PC aa C36:6 / 1.41±0.20 / 2.80±0.28 / 0.0003 / 1.78±0.51 / 2.55±0.39 / NS / NS / NS
PC aa C38:0 / 3.08±0.39 / 4.44±0.55 / 0.0395 / 4.39±0.65 / 4.61±0.80 / NS / NS / NS
PC aa C38:1 / 1.44±0.29 / 2.59±0.69 / NS / 2.43±1.05 / 1.52±1.05 / NS / NS / NS
PC aa C38:3 / 74.27±9.93 / 48.15±6.48 / 0.0101 / 59.90±8.13 / 52.23±8.60 / NS / NS / NS
PC aa C38:4 / 126.50±8.27 / 91.87±6.74 / 0.0182 / 113.20±11.54 / 113.22±13.70 / NS / NS / 0.0418
PC aa C38:5 / 72.30±9.41 / 95.77±5.49 / NS / 61.57±5.53 / 106.48±25.86 / NS / NS / NS
PC aa C38:6 / 84.95±11.43 / 135.17±12.68 / 0.0148 / 89.65±9.62 / 138.87±21.05 / 0.0246 / NS / NS
PC aa C40:1 / 0.67±0.12 / 0.66±0.09 / NS / 0.59±0.10 / 0.63±0.10 / NS / NS / NS
PC aa C40:2 / 0.40±0.04 / 0.50±0.09 / NS / 0.56±0.07 / 0.55±0.08 / NS / NS / NS
PC aa C40:3 / 0.86±0.14 / 0.76±0.10 / NS / 0.73±0.11 / 0.61±0.19 / NS / NS / NS
PC aa C40:4 / 4.24±0.50 / 2.75±0.45 / 0.0102 / 3.28±0.20 / 3.17±0.27 / NS / NS / 0.0417
PC aa C40:5 / 12.68±2.39 / 13.44±1.93 / NS / 12.06±1.63 / 14.25±3.31 / NS / NS / NS
PC aa C40:6 / 26.40±4.25 / 43.08±5.52 / 0.0273 / 27.95±4.04 / 44.10±6.55 / 0.0096 / NS / NS
PC aa C42:0 / 0.60±0.05 / 0.97±0.12 / 0.0061 / 0.70±0.08 / 0.93±0.17 / NS / NS / NS
PC aa C42:1 / 0.35±0.03 / 0.37±0.05 / NS / 0.33±0.03 / 0.45±0.08 / NS / NS / NS
PC aa C42:2 / 0.27±0.02 / 0.29±0.03 / NS / 0.30±0.05 / 0.33±0.05 / NS / NS / NS
PC aa C42:4 / 0.26±0.04 / 0.24±0.03 / NS / 0.24±0.02 / 0.26±0.03 / NS / NS / NS
PC aa C42:5 / 0.43±0.07 / 0.43±0.05 / NS / 0.42±0.05 / 0.51±0.07 / NS / NS / NS
PC aa C42:6 / 0.58±0.12 / 0.59±0.04 / NS / 0.60±0.13 / 0.63±0.04 / NS / NS / NS
PC ae C30:0 / 0.46±0.05 / 0.61±0.06 / NS / 0.51±0.10 / 0.57±0.09 / NS / NS / NS
PC ae C30:1 / 0.41±0.12 / 0.44±0.10 / NS / 0.75±0.23 / 0.57±0.17 / NS / NS / NS
PC ae C30:2 / 0.18±0.02 / 0.26±0.03 / 0.0405 / 0.25±0.05 / 0.22±0.03 / NS / NS / NS
PC ae C32:1 / 2.63±0.29 / 2.92±0.32 / NS / 2.91±0.46 / 3.94±0.51 / NS / NS / NS
PC ae C32:2 / 0.87±0.08 / 0.83±0.04 / NS / 0.93±0.13 / 1.07±0.21 / NS / NS / NS
PC ae C34:0 / 1.49±0.24 / 1.83±0.15 / NS / 2.43±0.41 / 1.95±0.32 / NS / NS / NS
PC ae C34:1 / 12.97±1.43 / 9.54±0.99 / 0.0432 / 11.78±1.01 / 10.98±0.89 / NS / NS / NS
PC ae C34:2 / 13.13±1.72 / 11.33±1.49 / NS / 15.35±1.84 / 12.55±1.22 / NS / 0.0223 / NS
PC ae C34:3 / 9.15±1.05 / 8.38±1.26 / NS / 11.13±1.41 / 9.62±0.94 / NS / NS / NS
PC ae C36:0 / 2.00±0.17 / 1.84±0.25 / NS / 2.40±0.52 / 2.88±0.92 / NS / NS / NS
PC ae C36:1 / 10.48±1.54 / 8.30±0.74 / NS / 11.90±1.76 / 12.03±1.05 / NS / NS / 0.0107
PC ae C36:2 / 15.48±1.41 / 14.05±1.69 / NS / 16.65±2.20 / 15.45±1.33 / NS / NS / NS
PC ae C36:3 / 10.26±1.21 / 6.94±0.72 / 0.0114 / 11.57±1.72 / 7.78±1.04 / NS / NS / NS
PC ae C36:4 / 18.53±1.19 / 15.59±1.76 / NS / 20.55±1.87 / 16.88±1.39 / NS / 0.0371 / NS
PC ae C36:5 / 11.03±0.71 / 15.23±1.29 / 0.0029 / 12.96±1.45 / 15.48±2.13 / NS / NS / NS
PC ae C38:0 / 2.69±0.34 / 4.98±0.40 / 0.0045 / 3.00±0.40 / 5.11±0.55 / 0.0060 / NS / NS
PC ae C38:1 / 3.21±1.48 / 1.59±0.50 / NS / 1.92±0.75 / 3.06±0.69 / NS / NS / NS
PC ae C38:2 / 3.43±0.34 / 2.67±0.45 / NS / 3.45±0.96 / 3.71±0.52 / NS / NS / NS
PC ae C38:3 / 6.00±0.86 / 3.93±0.40 / NS / 5.34±0.31 / 4.33±0.68 / NS / NS / NS
PC ae C38:4 / 14.66±1.58 / 12.62±1.12 / NS / 16.77±1.32 / 13.84±0.94 / 0.0333 / NS / NS
PC ae C38:5 / 21.37±1.78 / 19.83±1.49 / NS / 21.97±1.44 / 20.58±1.91 / NS / NS / NS
PC ae C38:6 / 8.22±0.35 / 12.25±1.28 / 0.0371 / 8.51±1.47 / 13.01±2.04 / NS / NS / NS
PC ae C40:0 / 7.94±0.44 / 8.43±0.61 / NS / 8.47 / 8.84±0.28 / NS / NS / NS
PC ae C40:1 / 1.64±0.11 / 1.46±0.10 / NS / 1.49±0.10 / 1.60±0.16 / NS / NS / NS
PC ae C40:2 / 1.85±0.19 / 2.15±0.24 / NS / 1.92±0.33 / 1.99±0.43 / NS / NS / NS
PC ae C40:3 / 2.11±0.48 / 1.43±0.21 / NS / 1.71±0.45 / 1.57±0.32 / NS / NS / NS
PC ae C40:4 / 2.92±0.43 / 2.24±0.17 / NS / 3.03±0.34 / 2.51±0.42 / NS / NS / NS
PC ae C40:5 / 4.03±0.34 / 4.42±0.39 / NS / 3.88±0.38 / 5.20±0.72 / NS / NS / NS
PC ae C40:6 / 4.65±0.40 / 6.99±0.57 / 0.0088 / 5.82±0.81 / 7.24±0.97 / NS / NS / NS
PC ae C42:0 / 0.75±0.27 / 0.47±0.06 / NS / 0.48±0.04 / 0.48±0.06 / NS / NS / NS
PC ae C42:1 / 0.60±0.22 / 0.35±0.04 / NS / 0.44±0.05 / 0.40±0.06 / NS / NS / NS
PC ae C42:2 / 0.79±0.09 / 0.78±0.07 / NS / 0.71±0.14 / 0.85±0.13 / NS / NS / NS
PC ae C42:3 / 1.21±0.14 / 0.90±0.11 / NS / 0.96±0.12 / 0.89±0.13 / NS / NS / NS
PC ae C42:4 / 1.19±0.08 / 1.05±0.15 / NS / 1.26±0.13 / 1.20±0.07 / NS / NS / NS
PC ae C42:5 / 2.67±0.27 / 2.05±0.28 / 0.0018 / 2.80±0.21 / 2.06±0.26 / 0.0204 / NS / NS
PC ae C44:3 / 0.14±0.03 / 0.18±0.04 / NS / 0.19±0.04 / 0.15±0.03 / NS / NS / NS
PC ae C44:4 / 0.55±0.10 / 0.35±0.06 / 0.0136 / 0.41±0.06 / 0.45±0.07 / NS / NS / 0.0364
PC ae C44:5 / 2.19±0.23 / 1.80±027 / NS / 2.64±0.18 / 1.99±0.23 / NS / NS / NS
PC ae C44:6 / 1.43±0.18 / 1.74±0.17 / 0.0193 / 1.62±0.16 / 1.82±0.24 / NS / NS / NS
TOTAL / 2192.61±149.49 / 2007.53±114.84 / NS / 2385.90±219.81 / 2254.19±152.12 / NS / NS / NS

Data are shown as mean  SEM. Abbreviation:PC: phosphatidylcholine

Table B: Plasmasphingomyelins (SM) concentrations of responders and non-responders pre- and post n-3 PUFA supplementation.

Responders (n=6) / Non-Responders(n=6) / P value
Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Delta (post- pre n-3 PUFAs)
SM (OH) C14:1 / 5.83±0.60 / 5.74±0.76 / NS / 5.53±1.17 / 5.85±0.76 / NS / NS / NS
SM (OH) C16:1 / 3.06±0.25 / 3.33±0.37 / NS / 3.89±0.50 / 3.37±0.44 / NS / NS / NS
SM (OH) C22:1 / 11.62±1.81 / 13.26±2.08 / NS / 14.64±2.75 / 11.68±1.05 / NS / NS / NS
SM (OH) C22:2 / 8.60±1.01 / 9.32±1.23 / NS / 11.14±1.63 / 8.48±0.79 / NS / NS / NS
SM (OH) C24:1 / 1.29±0.21 / 1.56±0.19 / NS / 1.21±0.22 / 0.98±0.14 / NS / NS / NS
SM C16:0 / 109.98±15.14 / 10.25±13.08 / NS / 118.87±11.61 / 103.67±7.12 / NS / NS / NS
SM C16:1 / 17.47±1.48 / 15.05±1.48 / NS / 21.13±3.65 / 17.03±1.76 / NS / NS / NS
SM C18:0 / 19.21±2.45 / 20.08±2.67 / NS / 24.15±5.45 / 20.53±2.85 / NS / NS / NS
SM C18:1 / 10.14±0.91 / 9.40±1.37 / NS / 14.36±3.52 / 10.52±1.74 / NS / NS / NS
SM C20:2 / 0.85±0.15 / 0.79±0.16 / NS / 1.08±0.16 / 0.95±0.08 / NS / NS / NS
SM C22:3 / 4.27±1.63 / 2.62±1.18 / NS / 4.77±1.68 / 6.39±2.78 / NS / NS / NS
SM C24:0 / 22.45±2.82 / 21.15±5.13 / NS / 23.35±4.84 / 20.68±2.45 / NS / NS / NS
SM C24:1 / 26.69±10.62 / 39.80±7.89 / NS / 50.47±14.71 / 40.77±4.31 / NS / NS / NS
SM C26:0 / 0.22±0.05 / 0.29±0.07 / NS / 0.32±0.11 / 0.21±0.05 / NS / NS / NS
SM C26:1 / 0.37±0.09 / 0.29±0.06 / NS / 0.35±0.09 / 0.28±0.03 / NS / NS / NS
TOTAL / 241.33±34.03 / 241.63±33.12 / NS / 294.46±47.42 / 249.26±17.49 / NS / NS / NS

Data are shown as mean  SEM, NA since not quantified correctly in plasma.

Table C: Plasma lysophosphatidylcholines (lysoPC)concentrations of responders and non-responders pre- and post n-3 PUFA supplementation.

Responders (n=6) / Non-Responders(n=6) / P value
Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Delta (post- pre n-3 PUFAs)
lysoPC a C14:0 / NA / NA / NA / NA
lysoPC a C16:0 / 69.80±13.43 / 80.07±5.49 / NS / 78.40±9.01 / 86.77±13.66 / NS / NS / NS
lysoPC a C16:1 / 2.59±0.31 / 2.13±0.21 / NS / 2.34±0.24 / 2.20±0.16 / NS / NS / NS
lysoPC a C17:0 / 1.71±0.22 / 1.61±0.19 / NS / 1.66±0.29 / 1.92±0.35 / NS / NS / NS
lysoPC a C18:0 / 24.77±2.49 / 24.77±2.98 / NS / 25.30±3.38 / 27.32±4.19 / NS / NS / NS
lysoPC a C18:1 / 17.05±1.87 / 17.85±2.12 / NS / 14.54±3.25 / 18.14±2.18 / NS / NS / NS
lysoPC a C18:2 / 26.28±2.81 / 26.45±5.10 / NS / 23.20±4.80 / 21.22±3.31 / NS / NS / NS
lysoPC a C20:3 / 2.24±0.13 / 1.98±0.34 / NS / 1.97±0.37 / 1.46±0.14 / NS / NS / NS
lysoPC a C20:4 / 4.75±0.60 / 4.92±0.90 / NS / 5.13±0.60 / 4.32±0.20 / NS / NS / NS
lysoPC a C24:0 / 0.30±0.03 / 0.52±0.11 / NS / 0.51±0.08 / 0.64±0.14 / NS / NS / NS
lysoPC a C26:0 / 0.60±0.09 / 0.73±0.08 / NS / 1.29±0.29 / 0.76±0.18 / NS / NS / NS
lysoPC a C26:1 / NA / NA / NA / NA
lysoPC a C28:0 / 0.87±0.17 / 0.85±0.21 / NS / 0.95±0.20 / 1.22±0.26 / 0.0431 / NS / NS
lysoPC a C28:1 / 0.90±0.12 / 0.89±0.10 / NS / 1.02±0.10 / 1.14±0.23 / NS / NS / NS
lysoPC a C6:0 / 0.06±0.02 / 0.06±0.02 / NS / 0.08±0.02 / 0.08±0.03 / NS / NS / NS
TOTAL / 151.92±18.91 / 162.81±15.43 / NS / 156.29±20.20 / 167.18±22.71 / NS / NS / NS

Data are shown as mean  SEM, NA since not quantified correctly in plasma.

.

Table D: Plasma acylcarnitines (AC) concentrations of responders and non-responders pre- and post n-3 PUFA supplementation.

Responders (n=6) / Non-Responders(n=6) / P value
Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Delta (post- pre n-3 PUFAs)
C0 / DL-Carnitine / 25.45±2.13 / 23.77±1.47 / NS / 26.03±2.86 / 24.07±2.38 / NS / NS / NS
C10 / Decanoyl-L-carnitine / NA / NA / NA / NA
C10:1 / Decenoyl-L-carnitine / NA / NA / NA / NA
C10:2 / Decadienyl-L-carnitine / 0.02±0.00 / 0.04±0.01 / NS / 0.02±0.00 / 0.02±0.00 / NS / NS / NS
C12 / Dodecanoyl-L-carnitine / NA / NA / NA / NA
C12:1 / Dodecenoyl-L-carnitine / NA / NA / NA / NA
C12-DC / Dodecanedioyl-L-carnitine / NA / NA / NA / NA
C14 / Tetradecanoyl-L-carnitine / NA / NA / NA / NA
C14:1 / Tetradecenoyl-L-carnitine / 0.22±0.04 / 0.17±0.03 / NS / 0.19±0.02 / 0.19±0.01 / NS / NS / NS
C14:1-OH / Hydroxytetradecenoyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C14:2 / Tetradecadienyl-L-carnitine / 0.03±0.01 / 0.03±0.01 / NS / 0.03±0.00 / 0.02±0.00 / NS / NS / NS
C14:2-OH / Hydroxytetradecadienyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C16 / Hexadecanoyl-L-carnitine / NA / NA / NA / NA
C16:1-OH / Hydroxyhexadecenoyl-L-carnitine / NA / NA / NA / NA
C16:1 / Hexadecenoyl-L-carnitine / NA / NA / NA / NA
C16-OH / Hydroxyhexadecanoyl-L-carnitine / NA / NA / NA / NA
C16:2 / Hexadecadienyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C16:2-OH / Hydroxyhexadecadienyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / 0.0099
C18 / Octadecanoyl-L-carnitine / NA / NA / NA / NA
C18:1 / Octadecenoyl-L-carnitine / 0.11±0.02 / 0.10±0.01 / NS / 0.08±0.01 / 0.09±0.00 / NS / NS / 0.0078
C18:1-OH / Hydroxyoctadecenoyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C18:2 / Octadecadienyl-L-carnitine / 0.04±0.01 / 0.04±0.01 / NS / 0.04±0.00 / 0.03±0.00 / NS / NS / NS
C2 / Acetyl-L-carnitine / 4.71±0.73 / 5.58±1.24 / NS / 5.29±0.34 / 3.98±0.40 / 0.0491 / NS / NS
C3 / Propionyl-L-carnitine / NA / NA / NA / NA
C3-DC / Malonyl-L-carnitine / 0.05±0.01 / 0.05±0.01 / NS / 0.06±0.01 / 0.05±0.01 / NS / NS / NS
C3-OH / Hydroxypropionyl-L-carnitine / NA / NA / NA / NA
C3:1 / Propenyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C4 / Butyryl-L-carnitine / NA / NA / NA / NA
C4:1 / Butenyl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C5 / Valeryl-L-carnitine / NA / NA / NA / NA
C5-DC / Glutaryl-L-carnitine / 0.01±0.00 / 0.01±0.00 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C5-M-DC / Methylglutaryl-L-carnitine / 0.03±0.00 / 0.03±0.00 / NS / 0.03±0.00 / 0.03±0.00 / NS / NS / NS
C3-DC-M / Methylmalonyl-L-carnitine / NA / NA / NA / NA
C5:1 / Tiglyl-L-carnitine / 0.02±0.00 / 0.02±0.00 / NS / 0.02±0.00 / 0.03±0.00 / 0.0482 / NS / NS
C5:1-DC / Glutaconyl-L-carnitine / 0.02±0.02 / 0.03±0.01 / NS / 0.01±0.00 / 0.01±0.00 / NS / NS / NS
C6 / Hexanoyl-L-carnitine / NA / NA / NA / NA
C6:1 / Hexenoyl-L-carnitine / 0.01±0.00 / 0.02±0.00 / 0.0219 / 0.02±0.00 / 0.02±0.00 / NS / NS / NS
C7-DC / Pimelyl-L-carnitine / NA / NA / NA / NA
C8 / Octanoyl-L-carnitine / NA / NA / NA / NA
C8:1 / Octenoyl-L-carnitine / 0.12±0.02 / 0.14±0.02 / NS / 0.10±0.02 / 0.11±0.01 / NS / NS / NS
C9 / Nonayl-L-carnitine / 0.04±0.01 / 0.04±0.00 / NS / 0.04±0.00 / 0.04±0.01 / NS / NS / NS
Total / 30.90±2.50 / 30.10±2.53 / NS / 31.99±2.88 / 28.74±2.61 / NS / NS / NS

Data are shown as mean  SEM, NA since not quantified correctly in plasma.

Table E: Plasma amino acids (including proteinogenic + ornithine)concentrations of responders and non-responders pre- and post n-3 PUFA supplementation.

Responders (n=6) / Non-Responders(n=6) / P value
Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Delta (post- pre n-3 PUFAs)
Arginine / 104.87±11.80 / 94.40±8.06 / NS / 86.33±7.05 / 74.58±12.40 / NS / NS / NS
Glutamine / NA / NA / NA / NA
Glycine / 246.50±50.39 / 223.17±29.16 / NS / 260.17±39.77 / 218.33±24.40 / NS / NS / NS
Histidine / 87.38±3.46 / 87.32±9.32 / NS / 87.33±5.26 / 78.50±5.41 / 0.0119 / NS / NS
Methionine / 27.07±2.88 / 24.92±2.16 / NS / 26.90±1.77 / 24.52±1.53 / NS / NS
Ornithine / 46.42±5.41 / 39.85±5.39 / NS / 51.67±4.89 / 35.40±4.50 / NS / NS / NS
Phenylalanine / 47.75±3.38 / 40.63±1.95 / 0.0477 / 49.90±3.72 / 43.42±2.29 / NS / NS / NS
Proline / 166.17±22.18 / 142.00±15.46 / NS / 162.08±23.56 / 131.98±17.69 / 0.0392 / NS / NS
Serine / 82.32±11.63 / 77.28±8.39 / NS / 101.10±5.09 / 83.32±10.42 / NS / NS / NS
Threonine / 95.25±7.66 / 85.73±6.00 / NS / 111.12±15.29 / 78.72±6.68 / NS / NS / NS
Tryptophan / 64.32±2.49 / 59.13±4.20 / NS / 71.05±4.27 / 68.32±4.94 / NS / NS / NS
Tyrosine / 77.15±11.03 / 67.07±5.23 / NS / 71.67±5.72 / 63.27±6.84 / NS / NS / NS
Valine / 235.83±22.58 / 221.00±21.80 / NS / 281.67±31.44 / 244.83±20.30 / NS / NS / NS
xLeucine / 166.00±26.66 / 165.00±19.45 / NS / 167.33±10.31 / 163.28±15.18 / NS / NS / NS
Total / 1382.70±126.94 / 1268.37±70.52 / NS / 1457.27±93.82 / 1214.60±84.41 / NS / NS / NS

Data are shown as mean  SD, NA since not quantified correctly in plasma.

.

Table F: Plasmahexoses (sum of hexoses- 90 to 95% glucose) concentrations of responders and non-responders pre- and post n-3 PUFA supplementation.

Responders (n=6) / Non-Responders(n=6) / P value
Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Post
n-3 PUFAs / P value / Pre
n-3 PUFAs / Delta (post- pre n-3 PUFAs)
Hexoses / 4518.00±169.08 / 4199.00±116.01 / 0.0319 / 3857.33±228.73 / 4164.33±229.40 / NS / NS / NS

Data are shown as mean  SEM.