CURRICULUM VITAE

GAIL S. PRINS, Ph.D.

PRESENT ADDRESS: Department of Urology

University of Illinois at Chicago

820 South Wood Street, M/C 955

Chicago, IL 60612

312-413-9766 (phone); 312-996-1291 (FAX)

EDUCATIONAL BACKGROUND:

1970 - 1974 B.A. in Biology/Chemistry, summa cum laude

Trinity Christian College, Palos Heights, IL

1974 - 1979 Ph.D. in Physiology

Department of Physiology and Biophysics

University of Illinois Medical Center, Chicago, IL

1979-83 Postgraduate: NIH Postdoctoral Fellow

Department of Urology and Center for Reproductive Science

Northwestern University Medical School, Chicago, IL

ACADEMIC AND PROFESSIONAL POSITIONS:

2001-present Professor (tenured), Departments of Urology and Physiology,

College of Medicine, University of Illinois at Chicago

1996-2001 Associate Professor (tenured), Departments of Urology, OB/GYN, Physiology & Biophysics, University of Illinois

1996-present Director, University Andrology Laboratory, Department of Urology;

University of Illinois at Chicago

1997-present Full Member, Graduate Faculty, University of Illinois Graduate College

2005-present Full Member, Cancer Center, University of Illinois at Chicago

2005-2008 Program Leader, Prostate Cancer Working Group, UIC Cancer Center

1990-1995 Research Associate Professor, Department of Obstetrics & Gynecology, University of Illinois at Chicago

1983-1990 Assistant Professor, Department of Obstetrics and Gynecology,

Pritzker School of Medicine, University of Chicago

1983-1995 Attending Scientific Staff, Michael Reese Hospital, Department of Obstetrics & Gynecology, Division of Reproductive Endocrinology

1987-1995 Director, Reproductive Biology Laboratory, Michael Reese Hospital & Medical Center

1983-87 Director, University of Chicago-Michael Reese Hospital

In Vitro Fertilization Laboratory and Andrology Laboratory

AWARDS:

2009 Excellence in Urologic Research Award, Society for Basic Urologic Research - Society for Women in Urology

2006 American Urologic Assoc Lectureship Award, Society for Basic Urologic Research

2006 AUA Keynote Lectureship Award, American Society of Andrology

2001 Distinguished Service Award, American Society of Andrology

1985 Rosenthal Research Award, Michael Reese Research and Education Foundation

1980-82  NIH National Research Service Award (Individual Fellowship)

1975 Graduate Research Program Award, Argonne National Laboratory

1974 Undergraduate Research Program Award, Argonne National Laboratory

1973 VanderVelde Award for Academic Achievement, Trinity Christian College

GRANTS:

Active:

2009-11 National Institutes of Health, NIEHS, Principal Investigator, “Developmental Exposure to Low-dose Bisphenol A and Human Prostate Cancer Susceptibility”, Grand Opportunity RC2 ES018758

1989-11 National Institutes of Health, NIDDK, Principal Investigator, “Developmental Estrogenization of the Rat Prostate Gland", R01 DK40890-19

2008-12  National Institutes of Health, NIEHS, Principal Investigator, “Epigenetic Basis for Prostate Carcinogenesis following Early Estrogenic Exposures”, R01 ES015584

2008-11  National Institutes of Health, NCI, Principal Investigator, “Dietary Intervention for Bisphenol A-induced Susceptibility to Prostate Neoplasia”, R03CA136023

2009-12  Department of Defense, Prostate Cancer Research Program Idea Award, Co-Investigator (PI: S. Swanson, PhD), “Role of Growth Hormone in Prostate Cancer”, W81XWH-09-1-0399

2008-13 National Institutes of Health, NCI, Co-Investigator (PI: V. Freeman, MD) “Adiposity and Outcomes of Clinically Localized Prostate Cancer” R01 CA129140.

Completed:

2004-2008 National Institutes of Health, NCI, Co-Investigator (PI: A. Diamond, PhD), “Selenoproteins and Prostate Cancer”, R01 CA101053

2003-06  National Institutes of Health, NIEHS, Principal Investigator, “Estrogen imprinting of the prostate gland via gene methylation”, R21 ES12282

2003-06 Department of Defense, Co-Investigator (PI: S. Swanson, PhD), “Role of Growth Hormone in Prostate Cancer”

2002-07 National Institute of Health, NIEHS, Co-Investigator (PI: F. vom Saal, PhD),

“Developmental Toxicity of Environmental Chemicals”, R01 ES11283

2004-06 American Foundation of Urologic Disease Research Fellowship (on behalf of Dr. Liwei Huang), “The Role of Growth Hormone in Prostate Cancer”

2004-05 American Cancer Society, Co-PI (PI: D. Hales, PhD), “CYP1B1 and oxidative stress: markers for prostate disease”

2002-03 National Institute of Health, NIA, Co-Investigator (PI: S. Swanson, PhD), “Role of Growth Hormone in Prostate Cancer: Rodent Models”, R03 AG 20820

1998-01 Environmental Protection Agency, STAR Award, Principal Investigator, “Effects of early exposure to xenoestrogens on the prostate gland”, R826299

1999-01 National Institutes of Health, NCI, “Preclinical Toxicology of Chemopreventive Agents: Evaluation of Hydrogen Ion Concentration in Prostates from Rats and Dogs”, Co-Investigator (PI: A. Levine, PhD), N01-CN-95055

1997-01 NRSA Predoctoral Research Fellowship (on behalf of Carl Woodham), “Prostatic androgen receptor regulation by neonatal estrogens”, F32 DK09653

1998-00 American Foundation of Urologic Disease Research Fellowship (on behalf of Dr. William Chang), “Retinoic acid receptors in estrogenized rat prostate”

1998-00 NRSA Postdoctoral Research Fellowship, NIH (on behalf of Dr. William Chang), “Retinoic acid receptors in estrogenized rat prostate”, F32 DK09873

1992-95 Research and Education Foundation Grant, Michael Reese Hospital, Principal Investigator, "Prostate cancer androgen receptor by immunocytochemistry"

1991-92 Medical Research Institute Council, Michael Reese Hospital, Principal Investigator, "Neonatal and prepubertal imprinting of the adult prostate gland",

1988-90 American Cancer Society, Principal Investigator, "Hormonal regulation of prostate steroid receptors", Grant # PDT-358

1985-87 Michael Reese Medical Research Institute, Principal Investigator, "Prolactin testosterone synergism in regulating growth of the prostate: prolactin's effect on the androgen receptor system", BRSG S07 RR 054476

1980-82  NRSA Individual Research Fellowship, National Institutes of Health, "Prolactin testosterone synergism in the rat prostate gland", F32 HD06175

PROFESSIONAL SOCIETY MEMBERSHIPS:

American Society of Andrology

Endocrine Society

Society for Basic Urologic Research

Society for the Study of Reproduction Society for Developmental Biology

American Association Cancer Research

American Urologic Association

American Society Reproductive Medicine

American Association of Anatomists

American Association of Bioanalysts

American Association of Tissue Banks AAAS

International Society for Developmental Origins of Health & Disease

COMMITTEE SERVICE:

INTRAMURAL:

2010-11 Review Committee for Anatomy & Cell Biology Department Head, UIC

2009 Search Committee, Director of Basic Research, Cancer Center, UIC

2008-09  Search Committee, Head of Pathology, UIC

2007-08 Executive Advisory Committee, Cancer Center, UIC

2007-08 Review Committee for Pharmacology Department Head, UIC

2006-09 Chair, Prostate Cancer Research Working Group, UIC Cancer Center,

2002-04 Academic Freedom and Tenure Committee, UIC Senate

2000-08 CME Committee, UIC College of Medicine

2000-05 Academic Affairs Committee, UIC College of Medicine

1999-02 Faculty Senate, UIC

2000-02 Senate Faculty Affairs Committee

2000-02 Senate Research Committee

1998-03 Admissions Committee, MD/PhD Training Program, UIC

2001-04 Teaching Awards Selection Committee, UIC College of Medicine

1998-02 Committee on Research, UIC College of Medicine

1998-99 Search Committee, Head of Biochemistry & Molecular Biology, UIC

1997-98 Search Committee, Head of Obstetrics & Gynecology, UIC

1995-98 Steering Committee, Prostate Cancer Program, University of Chicago

1990-96 Institutional Animal Care and Use Committee, MRH

1988-96 Institutional Research Committee, MRH

1995-96 Research Radioisotope Committee, MRH

1990-92 Committee on Research, University of Illinois College of Medicine

1988-92  Institutional Review Board, MRH

EXTRAMURAL:

2010-11  Planning Committee; Chair, Abstract Review Committee

Department of Defense Conference: Innovative Minds in Prostate Cancer Today (IMPACT-II)

2010 Organizing Committee, Illinois Symposium on Reproductive Sciences in Health & Disease

2009-12 Annual Meeting Program Steering Committee, The Endocrine Society

2003-09 Chair, Development Committee, American Society of Andrology

2008-09  Nominating Committee, Endowment & Growth Committee,

Society for Basic Urologic Research

2008-10 AUA Foundation Liaison, Society for Basic Urologic Research

2007-10 Program Committee, American Society of Andrology

2006-07  Planning Committee, Department of Defense Conference:

Innovative Minds in Prostate Cancer Today (IMPACT)

2004-05 Organizing Committee, AUA/SBUR Summer Research Conference

2000-03 Chair, Membership Committee, Society for Basic Urologic Research

2003-04 Development Committee, Society for the Study of Reproduction

1999-03 Chair, Finance Committee, American Society of Andrology

2000-03 Associates Committee, The Endocrine Society

2001-02 Awards Committee, Society for the Study of Reproduction

1998-01 By-Laws Committee, American Association of Tissue Banks

1999-03 Program Committee, American Society of Andrology

1997-02 Steering Committee, Chicago Prostate Consortium

1997-00 Membership Committee, Society for Basic Urologic Research

1996-97 Liaison Committee, Male Reproduction and Sexual Function

1996-97 Chair, Liaison Committee, Society for Basic Urologic Research

1992-93 Nominating Committee, American Society of Andrology

1992-93 Andrology Laboratory Committee, American Society of Andrology

1991-93 Nominating Committee, RBPG, American Fertility Society

1993 Prize Presentation Committee, American Fertility Society

1987-90 Chair, Student Affairs Committee, American Society of Andrology

1988-90  Membership Committee, American Society of Andrology

PROFESSIONAL SERVICE and ACTIVITIES:

1.  President American Society of Andrology (2003-2004)

2.  Treasurer American Society of Andrology (1994-1998)

3.  Chair Gordon Research Conference: Hormone Action in Development & Cancer, 2009

4.  Board Memberships:

2008-10 Board of Directors, Society for Basic Urologic Research

2008-10 Board of Directors, Society for Male Reproduction and Urology

2007-09  Council Member, Gordon Research Conferences

1990-93  Executive Council, American Society of Andrology

5.  Editorial Appointments:

Associate Editor

1992-1997  Journal of Andrology

Editorial Board

1998-2002  Endocrinology

2005-2014 Asian Journal of Andrology

2006-2011 Prostate

2006-2010 Reproductive Toxicology

2008-2011  Journal of Andrology

2008-2012  Open Prostate Cancer Journal

Journal Reviewer (ad Hoc):

Nature

PNAS

Cancer Research

Cancer

Oncogene

Differentiation

Molecular Endocrinology

Endocrinology

Journal of Endocrinology

Endocrine

Neuroendocrinology

American Journal of Physiology

Environmental Health Perspectives Journal of Toxicology

Biology of Reproduction

Fertility and Sterility

Journal of Reproduction & Fertility, Urology

Journal of Urology

International Journal of Andrology Molecular Reprod & Development

J Assisted Reproduction

J Histochemistry & Cytochemistry

6.  Grant Review Panels and Study Sections:

1988 NIH-RRC Site Reviewer, Oregon Regional Primate Research Center

1993  NIH Special Emphasis Panel: Regulation of Prostatic Growth

1995 NIH Biochemical Endocrinology Study Section (ad hoc)

1996 NIH Reproductive Endocrinology Study Section (ad hoc)

1998 DOD Prostate Cancer Research Program, Molecular Biology Panel

1998 NIH Pathology B Study Section (ad hoc)

1999-02 NIH/NIDDK Special Emphasis Panel: Urology Centers

1999 NIH/NIDDK Program Project Site Reviewer

2002 NIH Special Emphasis Panel: Infertility Research Centers

2001-03  NIH Special Emphasis Panel: Reproductive Endocrinology

2005 NIH ZRG1 Review Panel

2005 NIH Small Business Innovation Research Panel

2005 NIH/NCI Program Project Grants Study Section (ad Hoc)

2001 NIH/NIEHS Program Project Site Reviewer (ad Hoc)

2001-present National Assessors Panel for Cancer Research, Victoria, Australia

2003-05  NIH/NIEHS Program Project Reviewer (Chair)

2008 AUA Foundation Research Scholars Program Review Committee

2008 NIH Diabetes, Obesity, Nutrition, Reproduction Study Section

2009-10 NIH DKUS-A/B Review Panel

2009 NIH SEP: Epigenomics Challenge Grants (March)

2010 NIH EMNR-E (10) B; Small Business: Diabetes, Obesity and Nutrition

2010 NIH UKUS-C03 ZRG1 Review Panel

2011 NIH/NIEHS ZES1 RAM-D (LR) Special Emphasis Panel – Loan Repayment Grants

6. Scientific Advisory Panels:

2000-01  National Toxicology Program-NIEHS Endocrine Disruptors Low-Dose

Peer Review Panel

2000-07  Department of Defense Prostate Cancer Research Program

Integration Panel (IP) Member

Executive Committee Member, 2002-2006

2004-08 NIH – National Institute of Environmental Health Science

External Scientific Review Committee

2004-present Center for Cancer Research and Therapeutic Development,

Clark-Atlanta University, External Advisory Committee

2006-07  NIEHS-EPA Bisphenol A Review Panel (Chapel Hill Report), Chair: Cancer Section

2007-08  American Urological Assn: Male Infertility Best Practice Policy Panel

2007-09  Endocrine Society Endocrine Disruptor Task Force

2010-present Science Communication Network, Advisory Board

2010-11 American Urological Association: Vasectomy Guideline Panel

9.  Scientific Session/Symposium Moderator:

1989-2011 American Society of Andrology Meeting

1990-2000 American Society of Reproductive Medicine

1994 American Association for Cancer Research

1997, 2001 Gordon Research Conference: Hormonal Carcinogenesis

1998, 2004 Gordon Research Conference: Reproductive Tract Biology

1999-2005 Endocrine Society Annual Meeting

2001 Fourth World Congress in Urologic Research

2004-2005  AUA Annual Meeting: Male Infertility Take-Home Message

2006-08  Innovative Minds in Prostate Cancer Today, Dept of Defense

2006-10 SBUR Annual Meeting

2011 Innovative Minds in Prostate Cancer Today-II, Dept of Defense

2011 Gordon Research Conference: Hormone Action in Development and Cancer

10. Certification:

1994-present High Complexity Clinical Laboratory Director (HCLD)

American Association of Bioanalysts

TEACHING:

2001-2005 Human Physiology & Pathophysiology 302: Male Reproduction Lectures

2004-present Graduate College Integrative Lecture Series 510: Hormones & Cancer

2008-present College of Pharmacy: Cancer Biology and Therapeutics Course; Prostate Cancer Lectures

2009-present Graduate College Reproductive Physiology 504: Male Reproduction and Prostate Gland Biology & Cancer

2010 Graduate College Pathobiology of Cancer: Path 511: Developmental Origin of Adult Disease: Implications for Cancer

LABORATORY TRAINEES:

PhD Thesis Supervisor:

1998-2004 Carl Woodham, PhD, (NRSA recipient)

2008- Esther Calderon, MS

2008- Ikenna Madueke (MD/PhD Program)

Doctoral Dissertation Committee:

1999 Jennifer McCafferty, PhD, University of Miami School of Medicine

2001 Jason Derry, PhD, Department of Molecular Genetics, UIC

2001 Dubravka Markovic, PhD, Dept of Microbiology & Immunology, UIC

2002 Yan Wang, PhD, College of Pharmacy, UIC

2004 Natasa D. Pajkovic, PhD, College of Pharmacy, UIC

2004  Zhouhua Wang, PhD, College of Pharmacy, UIC

2005  Carrie Frazer, PhD, 2006, Department of Molecular Genetics, UIC

2009 Ang Lui, PhD, 2009, College of Pharmacy, UIC

present Patrick Brauer, PhD candidate, Department of Molecular Genetics, UIC

present Dong Wei, PhD candidate, College of Pharmacy, UIC

Postdoctoral Fellows:

1997-2000 William Chang, DVM, PhD, (AFUD Scholar; NRSA Fellow)

1998-2002 Oliver Putz, PhD

2001-2007 Yong Bing Pu, MD, PhD,

2001-2007 Liwei Huang, MD, PhD, (AFUD Scholar)

2007-present Doug Luccio-Camelo, PhD

2009-present Guangbin Shi, PhD

Research Assistant Professors:

2007-present Wenyang Hu, PhD, UIC

2008-present Shu-Hua Ye, MD, UIC

Visiting Scientists:

1990-96 Shu-Hua Ye, MD, Research Associate, University of Illinois

1998-00 Helga Habermann, MD, Assistant Professor, University of Gratz, Austria

2008-09 Ji Wen, MD, Professor, Second Hospital ofShandong University, Jianan, China,

Research Residents:

1987-88 Roger Lalich, DO,University of Wisconsin

1991-92 C. Sawetawan, MD, University of Texas

1995 Brijesh Kapoor, MD

1996-97 Michael Marmar, MD

1997-98 Steven Kim, MD

1998-99  Christopher Schwartz, MD

1999-00 Vibha Sabharwal MD

2000-01 Patrick Springhart, MD

2001-2002 Jason Gilleran, MD, University of Texas Southwestern

2002-2003 Shumyle Alam, MD,University of Kentucky

2004-2005 David Hepps, MD, University of Miami

2007-2008  Robin Lee, MD

2008-2009  Graham VerLee, M.D.

2010-2011 Jason Nelles, MD

Medical Students:

1988-89 Suresh Vedantham, MD, Professor, Washington University

2003-2004  Christina Dothinger, MD

2006-2007  Jessica de Frausto Belmonte, MD

2009-2011 Ricardo R. Rios

Research Awards to Trainees:

2006 Liwei Huang, MD, PhD, New Investigator Award, American Society of Andrology

2004-2006  Liwei Huang, MD, PhD, American Foundation Urologic Research Scholar

2004 Yongbing Pu, MD, Urology Trainee Travel Award, American Society of Andrology

2003 Liwei Huang, MD, PhD, Travel Award, AUA Summer Research Conference

2003 Yongbing Pu, MD, PhD, Travel Award, AUA Summer Research Conference

2003 Yongbing Pu, MD, PhD, Travel Award for Exceptional Research, Endocrine Society.

1998-2001  Carl Woodham, PhD, NRSA Predoctoral Fellowship Recipient

1998-2000 William Chang, DVM, PhD, NRSA Postdoctoral Fellowship Recipient

1998-2000  William Chang, DVM, PhD, American Foundation Urologic Research Scholar

2009-present Ikenna Madueke, graduate student, NIH Diversity Supplement Award

2010-2011 Ikenna Madueke, NIDDK T32DK007739-14: “Training in Signal Transduction and Cellular Endocrinology”, Predoctoral Fellowship

PUBLICATIONS:

PEER-REVIEWED JOURNAL ARTICLES: