Curriculum Vita of Mu-ming Poo

BIRTHDATE: October 31, 1948 BIRTH PLACE: Nanjing, China

CITIZENSHIP: U.S. (naturalized)

EDUCATION: B.S. (physics), Tsinghua University, Taiwan (1970)

Ph.D. (biophysics), Johns Hopkins University (1974)

POSITIONS:

1974 - 1976: Postdoctoral Fellow, Marine Biological Laboratory, Woods Hole, and Department of Biological Sciences, Purdue University.

1976 - 1979: Assistant Professor, Dept. of Physiology and Biophysics, Univ. Calif. at Irvine.

1979 - 1983: Associate Professor, Dept. of Physiology and Biophysics, Univ. Calif. at Irvine.

1983 - 1985: Professor, Dept. of Physiology and Biophysics, Univ. Calif. at Irvine.

1985 - 1988: Research Professor, Section of Molecular Neurobiology, Yale Univ. School of Medicine

1988 - 1995: Professor, Dept. of Biological Sciences, Columbia University.

1996 - 2000: Stephen W. Kuffler Professor in Neurobiology, Dept. of Biology, Univ. Calif. San Diego.

1999 - : Director, Institute of Neuroscience, Chinese Academy of Sciences, Shanghai

2000 - 2005: Professor of Neurobiology, Class of 1933 Chair in Biological Sciences, U.C. Berkeley

2002 - 2007: Head, Division of Neurobiology, Dept. of Molecular and Cell Biology, U.C. Berkeley

2005 - : Paul Licht Distinguished Professor in Biology, U. C. Berkeley

HONORS and AWARDs:

Javitz Neuroscience Investigator Award of NIH (98).

Academician, Academia Sinica. Taiwan (00).

Fellow, American Association for Advancement of Science (01).

Ameritec Prize (01).

Ray Wu Society Award (02).

Docteur Honoris Causa, Ecole Normale Supérieure, Paris (03).

Peoples Republic of China International Science & Technology Cooperation Award (05).

Member, National Academy of Sciences U.S. (09)

PROFESSIONAL ACTIVITIES and Services:

Developmental Neuroscience Panel, National Science Foundation (85-88).

Cell Biology and Physiology Study Section, National Institutes of Health (89–93)

Ad Hoc member, NIH study sections

Member, Hong Kong University of Science and Technology Preparatory Committee (89-91)

Long-term Fellowship Review Board, Human Frontier Science Program (97-99)

Brain Research Center, University System of Taiwan (since 02)

Peter Gruber Foundation Neuroscience Prize Committee (04-05)

Neuroscience School Board of International Brain Research Organization (01-07)

Executive committee, Helen Wills Neuroscience Institute (01-09)

Scientific Advisory Board, Institute of Molecular Biology, Academia Sinica (02-).Chair (08-)

Scientific Advisory Board, Brain Science Institute, RIKEN, Tokyo (03-).

Advisory Council, National Yang Ming University (04-)

Advisory Council, National Tsinghua University, Taiwan (05-).

Scientific Advisory Board, Friedrich Miescher Institute, Switzerland (06-).

Scientific Advisory Board, Institute of Linguistics, Academia Sinica (07-).

Scientific Advisory Board, Cold Spring Harbor Conferences, Asia (08-)

Ralph Gerald Neuroscience Award Committee (08-)

Scientific Advisory Board, National Center for Biological Sciences, Bangalore, India (07-09).

Scientific Advisory Board, Biotherapeutics & Bioinnovation Center, Pfizer (08-09)

Editorial Board, Journal of Cell Biology (94-01)

Editorial Board, Neuron (99-)

Editorial Board, Journal of Neuroscience (99-04)

Editorial Board, Journal of Biomedical Sciences (94-99)

Editorial Board, NeuroSignals (01-).

Editor, Biochemical and Biophysical Research Communications (03-09).

Editorial Board, Current Opinions in Neurobiology (04-).

Editorial Board, Network (05-).

Editorial Board, Progress in Neurobiology (05-).

Editorial Board, Experimental Neurology (06-).

Editorial Board, Neural Development (06-).

Editorial Board, International Journal of Clinical and Experimental Pathology (since 07).

Editorial Board, Journal of Physiology (07-)

Editor, Developmental Neurobiology (08-).

PUBLICATIONS:

1. Poo, M-m. and R.A. Cone. Lateral diffusion of rhodopsin in Necturus rod. Exp. Eye Res. 17:503-514 (1973).

2. Poo, M-m. and R.A. Cone. Lateral diffusion of rhodopsin in the photoreceptor membrane. Nature 247:438-441 (1974).

  1. Nuccitelli, R., Poo, M-m. and L.F. Jaffe. Relations between ameboid movement and membrane-controlled electrical currents. J. Gen. Physiol. 69:743-763 (1977).
  1. Hudspeth, A.J., Poo, M-m. and A.J. Stuart. Passive signal propagation and membrane properties in medial photoreceptors of the giant barnacle. J. Physiol. (Lond.) 272:25-43 (1977).
  1. Poo, M-m. and K.R. Robinson. Electrophoresis of concanavalin A receptors in the membrane of embryonic muscle cells. Nature 265:602-605 (1977).

6. Poo, M-m., Poo, W-j.H. and J.W. Lam. Lateral electrophoresis and diffusion of Concanavalin A receptors in the membrane of embryonic muscle cells. J. Cell Biol. 76:483-501 (1978).

7. Orida, N.K. and M-m. Poo. Electrophoretic movement and localization of acetylcholine receptors in the embryonic muscle cell membrane. Nature 275: 31-35 (1978).

8. Poo, M-m., Lam, J.W., Orida, N.K. and A.W. Chao. Electrophoresis and diffusion in the plane of cell membrane. Biophys. J. 26:1-22 (1979).

9. Jaffe, L.F. and M-m. Poo. Neurites grow faster towards the cathode than the anode in a steady field. J. Exp. Zool. 209:115-127 (1979).

10. Poo, M-m. Molecular movement of cell surface receptors. Biorheology 16: 309-315 (1979).

11. Orida, N.K. and M-m. Poo. On the developmental regulation of acetylcholine receptor mobility in the Xenopus embryonic muscle membrane. Exp. Cell Res. 130:281-290 (1980).

12. McLaughlin, S. and M-m. Poo. The role of electro-osmosis in the electric field-induced movement of charged macromolecules on the cell surface. Biophys. J. 34:85-93 (1981).

13. Orida, N. and M-m. Poo. Maintenance and dissolution of acetylcholine receptor clusters in the embryonic muscle cell membrane. Dev. Brain Res. 1:293-298 (1981).

14. Chao, N-m., Young, S.H. and M-m. Poo. Localization of cell membrane components by surface diffusion into a "trap". Biophys. J. 36:139-153 (1981).

  1. Poo, M-m. In situ electrophoresis of membrane components. Ann. Rev. Biophys. Bioeng. 10:245-276 (1981).

16. Patel, N. and M-m. Poo. Orientation of neurite growth by extracellular electric field. J. Neurosci. 2:483-496 (1982).

17. Poo, M-m. Rapid lateral diffusion of functional acetylcholine receptors in embryonic muscle membrane. Nature 295:332-334 (1982).

18. Chow, I. and M-m. Poo. Redistribution of cell surface receptors induced by cell-cell contact. J. Cell Biol. 95:510-518 (1982).

19. Fraser, S.E. and M-m. Poo. Development, maintenance, and modulation of patterned membrane topography. Models based on acetylcholine receptors. Curr. Top. Dev. Biol. 17:77-100 (1982).

20. Young, S.H. and M-m. Poo. Rapid lateral diffusion of extra-junctional acetylcholine receptors in Xenopus tadpole myotomes. J. Neurosci. 3:225-231 (1983).

21. Young, S.H. and M-m. Poo. Topographic rearrangement of ACh receptors alters channel kinetics. Nature 304:161-163 (1983).

22. Wu, C-f., Suzuki, N. and M-m. Poo. Dissociated neurons from normal and mutant Drosophila larval CNS in cell culture. J. Neurosci. 3:1888-1899 (1983).

23. Young, S.H. and M-m. Poo. Spontaneous release of transmitter from growth cone of embryonic neuron. Nature 305:634-637 (1983).

24. Chow, I. and M-m. Poo. Formation of electrical coupling between embryonic Xenopus muscle cells in culture. J. Physiol. (Lond.) 346:181-194 (1984).

25. McCloskey, M. and M-m. Poo. Protein diffusion in cell membranes: Some biological implications. Int. Rev. Cytol. 87:19-81 (1984).

26. Lin-Liu, S., Adey, W.R. and M-m. Poo. Migration of cell surface concanavalin A receptors in pulsed electric fields. Biophys. J. 45:1121-1218 (1984).

27. McCloskey, M., Liu. Z. and M-m. Poo. Lateral electromigration and diffusion of Fc receptors on rat basophilic leukemia cells: Effects of IgE binding. J. Cell Biol. 99:778-787 (1984).

28. Young, S., McCloskey, M. and M-m. Poo. Migration of cell surface receptors induced by extracellular electric fields: Theory and applications. The Receptors Vol. 1, M.Conn ed., pp. 511-539. Academic Press, Inc. (1984).

29. Patel, N.B. and M-m. Poo. Perturbation of the direction of neurite growth by pulsed and focal electric fields. J. Neurosci. 4:2939-2947 (1984).

  1. Patel, N.B., Xie Z-p., Young, S. and M-m. Poo. Response of nerve growth cone to focal electric currents. J. Neurosci. Res. 13:245-256 (1985).

31. Poo, M-m. Mobility and localization of proteins in excitable membranes. Ann. Rev. Neurosci. 8:368-406 (1985).

32. Sun, Y-a. and M-m. Poo. Non-quantal release of acetylcholine at a developing neuromuscular synapse in culture. J. Neurosci. 5:634-642 (1985).

33. Chow, I. and M-m. Poo. Release of acetylcholine from embryonic neurons upon contact with muscle cell. J. Neurosci. 5:1076-1082 (1985).

34. Poo, M-m., Sun, I-a. and Young, S. Three types of transmitter release from embryonic neurons in culture. J. Physiol. (Paris) 80: 283-298 (1985).

35. McCloskey, M. and M-m. Poo. Rates of membrane-associated reactions: Reduction of dimensionality revisited. J. Cell Biol. 102:88-96 (1985).

36. Peng, H.B. and M-m. Poo. Formation and dispersal of acetylcholine receptor clusters in muscle membranes. Trends in Neurosci. 9:125-129 (1986).

37. McCloskey, M. and M-m. Poo. Contact-induced redistribution of specific membrane components: Local accumulation and development of adhesion. J. Cell Biol. 102:2185-2196 (1986).

38. Xie, Z-p. and M-m. Poo. Initial events in the formation of neuromuscular synapse: Rapid induction of acetylcholine release. Proc. Natl. Acad. Sci. USA 83:7069-7073 (1986).

39. Sun, Y-a. and M-m. Poo. Evoked release of transmitter from growing embryonic neuron. Proc. Natl. Acad. Sci. USA 84:2540-2544 (1987).

40. Torney, D., Warnock T. McCloskey, M. Dembo M., and M-m. Poo. Rate theories for chemical reactions taking place in two dimensions. Comments Mol. Cell. Biophys. 4:281-303 (1987).

41. Poo, M-m. Transmitter release and synaptogenesis. In Peripheral Nerve Regeneration, ed. T Gordon and G. Vrbova, Alan R. Liss, Inc. p.203-212 (1987).

42. Sanes, D., and M-m. Poo. Early events in nerve-muscle interaction. Ciba Foundation Symposium Publication, p. 116-130. John Wiley & Sons (1988).

43. Poo, M-m. and Buchanan, J. Transmitter release and nerve-muscle interaction during the early phase of synaptogenesis. In Neuromuscular Junction, Sellin, L.C., Sibelius R. and Thesleff, S. Ed. p. 541-550. Elsevier Publishers (1988).

44. Sanes, D, and Poo, M-m. In vitro analysis of position- and lineage-dependent selectivity in the formation of nerve-muscle synapses. Neuron 2:1237-1244 (1989).

45. Buchanan, J., Sun, Y-a., and Poo, M-m. Studies of nerve-muscle interactions in Xenopus cell culture: Morphology of early functional contacts. J. Neurosci. 9:1540-1554 (1989).

46. Evers, J., Laser, M., Sun, Y-a., Xie, Z-p., and Poo, M-m. Studies of nerve-muscle interactions in Xenopus cell culture: Analysis of early synaptic currents. J. Neurosci. 9:1523-1539 (1989).

47. Poo, M-m. and Brown, A. Physical and chemical interactons during the early phase of synaptogenesis. In “Assembly of Nervous Systems”, ed. L. Landmesser, Alan Liss, N.Y. p.199-212 (1989).

48. Hartman, D.S., Poo, M-m., Green, W.N., Ross, A.F. and Claudio, T. Synaptic contact between embryonic neurons and ACh receptor fibroblasts. J. Physiol. (Paris) 84:42-49 (1990).

49. Poo, M-m. and Young, S.H. Diffusional redistribution and electrokinetic accumulation: Physicochemical mechanisms for synaptic competition. J. Neurobiol. 21:157-162 (1990).

50. Tabti, N. and Poo, M-m. Spontaneous secretion of transmitter at developing neuromuscular syapse. In Nobel Symposium on Neuromuscular Junctions, Elsevier, Amsterdam (1990).

51. Poo, M-m. and Quillan, M. Transmitter secretion and growth cone orientation. In Nerve Growth Cone, Ed. S. Kater, P. Letourneau, and E. Macagno. Plenum Press, NY. P.231-236 (1991).

52. Fu, W. and Poo, M-m. ATP potentiates spontaneous transmitter release at developing neuromuscular synapses. Neuron 6:837-843 (1991).

53. Lo, Y., Wang, T. and Poo, M-m. Potentiation of spontaneous ACh release by repetitive presynaptic activity. J. Physiol. (Paris) 85:71-78 (1991).

54. Tabti, N. and Poo, M-m. Culturing Xenopus nerve and muscle cells. In Culturing Nerve Cells, Ed. G. Banker, and T. Goslin, MIT press (1991).

55. Lo, Y. and Poo, M-m. Activity-dependent synaptic competition in vitro: Heterosynaptic suppression of developing synapses. Science 254:1019-1022 (1991).

56. Popov, S. and Poo, M-m. Diffusion of macromolecules in developing nerve processes. J. Neurosci. 12:77-85 (1992).

57. Lu, B., Greengard, P., and Poo, M-m. Synapsin-I promotes maturation of quantal synaptic transmission. Neuron 8:521-529 (1992).

58. Lohof, A., Quillan, M., Dan, Y., and Poo, M-m. (1992) Asymmetric modulation of cytosolic cAMP induces growth cone turning. J. Neurosci. 12:1253-1261.

59. Girod, R., Eder-Colli, L, Mcdilanski, Dunant, Y., Tabti, N. and Poo, M-m. (1992) Pulsatile release of acetylcholine by isolated nerve terminals (synaptosomes). J. Physiol. 450: 325-340.

60. Dan, Y. and Poo, M. (1992) Hebbian depression of isolated neuromuscular synapses in vitro. Science 256: 1570-1573.

61. Alder, J., Lu, B., Valtorta, F., Greengard, P., and Poo, M-m. (1992) Transmitter secretion reconstituted in Xenopus oocytes: Requirement for synaptophysin. Science 257: 657-661.

62. Dan, Y. and Poo, M-m. (1992) Quantal transmitter secretion from myocytes loaded with acetylcholine. Nature 359: 733-737.

63. Alder, J., Xie, Z, Valtorta, F., Greengard, P. and Poo, M-m. Antibody to synaptophysin interferes with transmitter release at developing neuromuscular synapse. Neuron 9: 759-768 (1992).

64. Brown, A. and Poo, M-m. Microsuction assay of cell-cell adhesion in culture. In "Practical Electrophysiological Methods", p. 349-353, John Wiley & Sons, Inc (1992).

65. Young, S. and Poo, M-m. Measurement of transmitter release: moving patch method. In "Practical Electrophysiological Methods", p. 354-357. John Wiley & Sons (1992).

66. Harish, O.E. and Poo, M-m. Retrograde modulation of transmitter secretion at developing synapses: Involvement of G proteins and arachidonic acid cascade. Neuron 9: 1201-1209 (1992).

67. Popov, S. Brown, A. and Poo, M-m. Forward plasma membrane flow in growing nerve processes. Science 259: 244-246 (1993).

68. Lu, B., Fu, W-m., Greengard, P., and Poo, M-m. CGRP potentiates synaptic responses at developing neuromuscular junction. Nature 363: 76-79 (1993).

69. Lohof, A., Ip, N. and Poo, M-m. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature 363: 350-353 (1993).

70. Alder, J. and Poo, M-m. Reconstitution of transmitter secretion mechanisms. Curr. Opin. Neurobiol. 3: 322-328 (1993).

71. Popov, S. and Poo, M-m. Synaptotagmin: A calcium-sensitive inhibitor of exocytosis? Cell 73: 1247-1249 (1993).

72. Shaeffer, E., Alder, J., Greengard, P., and Poo, M-m. Synapsin IIa accelerates functional development of neuromuscular synapses. Proc. Natl. Acad. Sci. USA. 91: 3882-3886 (1994).

  1. Tabti, N. and Poo, M-m. Spontaneous synaptic activity at developing neuromuscular junctions. Prog. Brain Res. 84: 63-72 (1994).
  1. Tabti, N. and Poo, M-m. Study of the induction of spontaneous transmitter release at early nerve-muscle contacts in Xenopus cultures. Neurosci. Lett. 173: 21-26 (1994).
  1. Dan, Y. and Poo, M-m. Ca2+-dependent postsynaptic exocytosis: a mechanism for activity-dependent synaptic modulation. J. Neurobiol. 25: 336-344 (1994).
  1. Dan, Y. and Poo, M-m. Retrograde interaction during formation and elimination of neuromuscular synapses. Curr. Opin. Neurobiol. 4: 95-100 (1994).
  1. Zheng, J., Felder, M., Connor, J., and Poo, M-m. Turning of nerve growth cones induced by neurotransmitters. Nature 368: 140-144 (1994).
  1. Lo, Y., and Poo, M-m. Heterosynaptic Suppression of developing neuromuscular synapses in culture. J. Neurosci. 14: 4684-4693 (1994).
  1. Lo, Y., Lin, Y-c., Sanes, D. and Poo, M-m. Depression of developing neuromuscular synapses induced by repetitive postsynaptic depolarizations. J. Neurosci. 14: 4694-4704 (1994).
  1. Popov, S., Girod, R., and Poo M-m. Neurotransmitter release from non-neuronal cells. Seminers in Neurosci. 6: 187-194 (1994).
  1. Dan, Y., Song, H-j., and Poo, M-m. Evoked secretion of false transmitters. Neuron 13: 909-17 (1994).
  1. Zheng, J., Zheng, Z., and Poo, M-m. Long-range signaling in growing neurons after local elevation of cAMP activity. J. Cell Biol. 127: 1693-1701 (1994).
  1. Alder, J., Kanki, H., Valtorta, F., Greengard, P., and Poo, M-m. Overexpression of synaptophysin enhanced spontaneous and evoked transmitter secretion. J. Neurosci. 15: 511-519 (1995).
  1. Stoop, R., and Poo, M-m. Potentiation of transmitter release by ciliary neurotrophic factor requires somatic signaling. Science 267: 695-699 (1995).
  1. Girod, R., Popov, S., Alder, J., , Lohof, A. and Poo, M-m. Quantal transmitter release from myocytes and fibroblasts: comparison with neuronal secretion. J. Neurosci. 15: 2826-38 (1995).
  1. Dan, D., Lo, Y. and Poo, M-m. Plasticity of developing neuromuscular synapses. Prog. Brain Res. 105: 211-5 (1995).
  1. Cash, S. and Poo, M-m. Presynaptic differentiation and retrograde signaling during the early phase of synaptogenesis. Seminars in Dev. Biol. 6: 185-193 (1995).
  1. Valtorta, F., Numa, L., Benfenati F., Lu, B., Poo, M-m. and Greengard, P. Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis. Eur. J. Neurosci. 7: 261-270 (1995).
  1. Morimoto, T., Popov, S., Buckley, K., and Poo, M-m. Calcium-dependent quantal transmitter release from fibroblasts: Modulation by synaptotagmin. Neuron 15: 689-696 (1995).
  1. Zheng, J., Wan, J., and Poo, M-m. Filopodia are essential for chemotactic turning of nerve growth cones. J. Neurosci. 16: 1140-1149 (1996).
  1. Winckler, B. and Poo, M-m. No diffusion barrier at the axonal hillock. Nature. 379: 213 (1996).
  1. Wang, X., Zheng, J.Q. and Poo, M-m. Cytochalasin B modulate short-term synaptic plasticity at developing neuromuscular junction. J. Physiol. 491: 187-195 (1996).
  1. Cash, S., Dan, Y. Poo, M-m. and Zucker, R. Depression of developing neuromuscular synapses by postsynaptic elevation of calcium. Neuron 16: 745-754 (1996).
  1. Cash, S., Zucker, R. and Poo, M-m. Spread of synaptic depression by presynaptic cytosolic signaling. Science 272: 998-1001 (1996).
  1. Stoop, R. and Poo M-m. Synaptic potentiation by neurotrophic factors: differential and synergistic actions of BDNF and CNTF. J. Neurosci. 16: 3256-3264 (1996).
  1. Stoop, R. and Poo, M-m. Synaptic modulation by neurotrophic factors. Prog. Brain Res. 109: 359-364 (1996).
  1. Poo, M-m. Dan Y., Song, H-j., Morimoto, T. and Popov, S. Calcium-dependent vesicular exocytosis: from constitutive to regulated secretion. Cold Spr. Har. Symp. Quant. Biol. V. 60: 349-359 (1996).
  1. Berlinger, B. and Poo, M-m. Fast actions of neurotrophic factors. Curr. Opin. Neurobiol. 6: 324-330 (1996).
  1. Lu, B., Czernik, A.J., Popov, S., Wang, T., Poo, M-m. and Greengard, P. Expression of synapsin I correlates with maturation of the neuromuscular synapse. Neurosci. 74: 1087-1097 (1996).
  1. Song, H-j. Ming, G-l., Fon, E., Bellocchio, E., Edwards, R. and Poo, M-m. Expression of a putative vesicular acetylcholine transporter facilitates quantal transmitter packaging. Neuron 18: 815-826 (1997).
  1. Lowen, S.B., Cash, S., M-m. Poo, and Teich M.C. Quantal neurotransmitter secretion rate exhibits fractal behavior. J. Neurosci. 17: 5666-5677 (1997).
  1. Song, H-j. Ming, G-l., and Poo M-m. A cAMP-induced switching of turning direction of nerve growth cones. Nature 388: 275-279 (1997).
  1. Fitzsimonds, R., Song, H-j. and Poo, M-m. Propagation of activity-dependent synaptic depression in small neural networks. Nature 388: 439-448 (1997).
  1. Wang, X-h. and M-m. Poo Synaptic potentiation by postsynaptic secretion of neurotrophin-4. Neuron, 19: 825-835 (1997).
  1. Morimoto, T., Wang, X-h. and Poo M-m. Overexpression of synaptotagmin modulates short-term synaptic plasticity. Neurosci. 82: 969-978 (1997).
  1. de la Torre, J., Hopker, V.H., Ming, G-l., Poo, M-m., Tessier-Lavigne, M., Hemmati-Brivanlou, A., and Holt, C.E. Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. Neuron 19, 1221-1224 (1997).
  1. Ming, G-l., Song, H-j. Berninger, B., C. Holt, M. Tessier-Lagvine, and Poo, M-m. cAMP-dependent growth cone guidance by netrin-1. Neuron 19, 1225-1235 (1997).
  1. Fitzsimonds, R. and Poo M-m. Retrograde signaling in the development and modification of synapses. Physiol. Rev. 78: 143-170 (1998).
  1. Sternfeld, M, Ming, G., Song, H., Sela, K., Timberg, R., Poo, M-m., and Soreq, H. Acetylcholinesterase enhances neurite growth and synapse development through alternative contributions of its hydrolytic capacity, core protein, and variable C termini. J. Neurosci. 18: 1240-1249 (1998).
  1. Wang, X-h., Berninger, B., and Poo, M-m. Localized synaptic actions of neurotrophin-4. J. Neurosci. 18: 4985-4992 (1998).
  1. Zhang, L., Tao, H-z., Holt, C., Harris, W., and Poo, M-m. A critical window in the cooperation and competition among developing retinotectal synapses. Nature 395: 37-44 (1998).
  1. Song, H-j., Ming, G-l., He, Z, Lehmann, M., McKerracher, L., Tessier-Lagvine, M., and Poo, M-m. Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science 281: 1515-1518 (1998).
  1. Bi, Q. and Poo, M-m. Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J. Neurosci. 18: 10464-10472 (1998).
  1. Boulanger, L. and Poo, M-m. Presynaptic depolarization facilitates neurotrophin-induced synaptic potentiation. Nat. Neurosci. 2: 346-351 (1999).
  1. Boulanger, L. and Poo, M-m. Gating of BDNF-induced synaptic potentiation by cAMP. Science 284:1982-1984 (1999).
  1. Song, H. and Poo, M-m. Growth cone guidance by diffusible factors. Cur. Opin. Neurobiol. 9: 355-363 (1999).
  1. Ming, G., Song, H., Berninger, B., Inagaki, N., Tessier-Lavigne, M., and Poo, M-m. Phospholipase C-r and phosphoinositide 3-kinase mediate cytoplasmic signaling in axon guidance. Neuron, 23: 139-148 (1999).
  1. Hong, K., Hinck, L., Nishiyama, M., Poo, M-m., Tessier-Lavinge, and Stein, E. A ligand-gated association between cytoplasmic domains of UNC5 and DCC receptors converts netrin-induced growth cone attraction to repulsion. Cell, 97:927-941 (1999).
  1. Hoeker, V., Shewan, D., Tessier-Lavigne, M., Poo, M-m., and Holt, C. Conversion of netrin-1 induced attraction to repulsion by laminin-1. Nature 401: 69-73 (1999).
  1. Berninger, B., Schinder, A., and Poo, M-m. Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor. Learning and Memory 6: 232-242 (1999).
  1. Wan, J. and Poo, M-m. Activity-induced potentiation of developing neuromuscular synapses. Science 285:1725-8 (1999).
  1. Tamagnone L., Artigiani, S., Chen, H., He, Z., Ming G., Song H., Chedotal, A., Goodman C.S., Poo M-m., Tessier-Lavigne, M., Comoglio P. M. Plexins are a large family of receptors for transmembrane, secreted, and GPI-Anchored semaphorins in vertebrates. Cell 99: 71–80 (1999)
  1. Bi, G. and Poo, M-m. Distributed synaptic modification in neural networks induced by patterned stimulation. Nature 401: 792-796 (1999).
  1. Hong, K., Nishiyama, M., Henley, J., Tessier-Lavigne, M., and Poo, M-m. Calcium signaling in the guidance of nerve growth by netrin-1. Nature 403: 93-98 (2000).
  1. Schinder, A., Berninger, B., and Poo, M-m. Target-cell specific potentiation of glutamatergic synapses by neurotrophins. Neuron 25: 151-163 (2000)
  1. Yao, W-d., Rusch J., Poo, M-m. and Wu, C-f. Spontaneous acetylcholine secretion from developing growth cones of Drosophila central neruons in culture: effects of cAMP pathway mutants. J. Neurosci. 20: 2626-2637 (2000).
  1. Tao, H., Zhang, L., Bi, G., and Poo, M-m. Selective presynaptic propagation of long-term potentiation in defined neural networks. J. Neurosci. 20: 3233-3243 (2000).
  1. Zhang, L., Tao, H., and Poo, M-m. Long-term potentiation of developing retinotectal synapses induced by visual inputs. Nat. Neurosci. 3: 708-715 (2000).
  1. Ganguly, K., Kiss, L., and Poo, M-m. Enhancement of presynaptic excitability by correlated pre- and postsynaptic spiking. Nat.