MINUTES
CPIC CONFERENCE CALL
DATE: May 3, 2012
PRESENT: Uli Broeckel, Trisha Brown, Tom Callaghan, Michelle Carrillo, Kristine Crews, Bob Freimuth, Andrea Gaedigk, Li Gong, Grace Kuo, James Hoffman, Kevin Hicks, Sam Johnson, Teri Klein, Deanna Kroetz, Grace Kuo, Susan Leckband, Mike Lee, Ellie McDonagh, Katrin Sangkuhl, Steve Scherer, Stuart Scott, Matthias Schwab, Jesse Swen, Todd Skaar, Ming Ta, Kathryn Teng, Mia Wadelius, Michelle Whirl-Carrillo, Sook-Wah Yee
TOPIC / DISCUSSION/ACTION / FOLLOW-UP /Guideline Updates / Susan Leckland (CBZ and SSRI)
· CBZ guideline is under review by Teri and Mary and will be distributed to the entire CPIC membership for review in about a week
· SSRI draft to be completed for review by CPIC membership in August and then on to CPT by September
Mike Lee (allopurinol)
· Draft sent to several oncologists for comments
· Should patient education be included in the guideline?
· So far this has been deemed outside of the scope of the guideline, but the idea was brought to the group for discussion
· Teri noted that PharmGKB is focused on clinicians and scientists and this was recently confirmed through PharmGKB’s
· Suggestion was that other groups, such as ASCPT could take on patient education for pharmacogenetics; Russ Altman is the incoming president of ASCPT and could be approached on this
· outside of the scope of CPIC
c.Kevin Hicks (TCA)
· rough draft done
· still dealing with number of drugs to include;
· working documents for all drugs now available for all authors to review before the call and then decisions should be able to be made quickly and the guideline can move forward quickly
Status of other Guidelines
· Statins – should be published soon – missed exact date?
· DPYD/fluorouracil – Caroline Thorn, Howard McLeod, Teri and now volunteering Matthias Schwab are working on the guideline. Issue at hand is definition of “PM”.
· G6PD/rasburicase – started between PharmGKB and St. Jude
· IL28B and Pegintron – draft in progress; working with Andrew Muir, Teri Klein, Li Gong
· HLA/Phenytoin – Tom Callaghan will take the lead. Michelle Carrillo, Teri Klein and Mike Lee to start guideline. Will work towards identifying clinicians in this area. / Author group to have a conference call in the next two weeks
Teri will get new author connected to group; conference call needs to take place
Will start to strategize next steps on guidelines – reminder to CPIC members to nominate gene/drug pairs where guidelines are needed
SOP will be created to provide more details of how to write a CPIC guideline
PharmGKB Demo (new UI) - Ellie McDonagh / · New design of PharmGKB was demonstrated to CPIC
· Note CPIC page is under “projects” tab; CPIC member site is at the bottom of the page
· Also, new CPIC graphic is listed at the bottom of the main PharmGKB page
· Questions about genetic test availability – noted intent is not to be comprehensive; plan is to link with the GTR; do get some requests for listing tests
· Teri noted that PharmGKB is always open for suggestions for new content or other changes to PharmGKB / Further enhancements to CPIC content are being planned over the next 6 months; changes will be brought to CPIC