consultant haematologist with an interest in haemopoietic stem cell transplantation
beatson, west of scotland cancer centre
INFORMATION PACK
REF: 36201D
cLOSING DATE: Noon 3rd April 2015
As you may be aware, the new South Glasgow University Hospital and new Royal Hospital for Sick Children are due to open on the current Southern site early in 2015.
With this in mind, please note that positions based within the Victoria Infirmary, Mansionhouse Unit, the Western Infirmary and the current Royal Hospital for Sick Children at Yorkhill will change location and move to the new hospitals.
Gartnavel General Hospital and Glasgow Royal Infirmary will also have some services affected by moves to the new Hospitals.
These changes mean your base may change after joining us and you will be informed as soon as possible prior to any change of base.
SUMMARY INFORMATION RELATING TO THIS POSITION
Post: consultant haematologist with an interest in HAEMOPOIETIC STEM CELL TRANSPLANTATION
Base: Beatson, west of scotland cancer centre
We are looking to recruit an experienced individual to join our department of 4 existing consultants. They will be part of the transplant team with additional work involving haemato-oncology patients. This post has been created to help support the newly created Scottish Adult Allogeneic Haematopoietic Stem Cell Transplant Service The unit will provide adult allogeneic transplant services for the 5.6 million people in Scotland. The West of Scotland Adult Haematopoietic Stem Cell Transplant Service (HSCTS) is one of the largest centres in the UK (23 siblings, 60 VUD, 2 cord transplants in 2014). It is currently based at the Beatson, West of Scotland Cancer Centre, and will move to the new South Glasgow Hospital in June 2015.
This will be one of the largest hospitals in the UK with more than 1100 beds, all in single rooms. The new children’s hospital, including Paediatric Haematology and transplantation will be co-located on the same campus which will also house other essential regional specialist services, including Respiratory, Gastroenterology, Neurology, Dermatology, acute surgical and Intensive therapy units. There are close links with the University of Glasgow and there are excellent opportunities for research and collaborative working.
The successful applicant will also be expected to contribute to the general haemato-oncology service. The post attracts 10PA in the first instance with a 1 in 5 on-call provision.
Applicants must have full registration with the General Medical Council, a licence to practise and be eligible for inclusion in the GMC Specialist Register. Those trained in the UK should have evidence of higher Specialist Training leading to a CCT or eligibility for specialist registration CESR (CP) or be within six months of confirmed entry at the date of interview. Non UK applicants must demonstrate equivalent training.
ACUTE SERVICES DIVISION
INFORMATION PACK
FOR THE POST OF
CONSULTANT
IN
HAEMATOLOGY
WITH AN INTEREST IN
HAEMATOPOIETIC STEM CELL TRANSPLANTATION
1. GLASGOW – A GREAT PLACE TO LIVE AND WORK
Greater Glasgow and the Clyde Valley is one of the world’s most thrilling and beautiful destinations.
There is a wealth of attractions to discover, the UK’s finest Victorian architecture to astound, internationally acclaimed museums and galleries to inspire, as well as Glasgow’s own unique atmosphere to soak up.
Be entertained in one of Europe’s top cultural capitals with its year-long calendar of festivals and special events and enjoy outstanding shopping, superb bars and restaurants - all located within a stone’s throw of some of the country’s finest parks and gardens.
The area also stands at the gateway to some of Scotland’s most spectacular scenery, with Loch Lomond and the Trossachs only 40 minutes away.
What’s more, we are easily accessible by air, rail and road so getting here could not be easier.
2. GREATER GLASGOW & CLYDE ACUTE
SERVICES DIVISION
The Acute Division brings together all acute services across the city and Clyde under a single management structure led by the Chief Operating Officer. The Division is made up of 6 Directorates of clinical services each managed by a Director and clinical management team along with a Facilities Directorate. These are:
Emergency Care and Medical Services
Surgery and Anaesthetics
Rehabilitation and Assessment
Diagnostics
Regional Services
Women’s and Children’s Services
Facilities
Regional Services
This post is based within the Regional Services Directorate which includes:
Neuro-sciences [including all sub-specialties except neuro-
Radiology and neuropathology]
Specialist Oncology Services
Clinical Haematology
Plastic Surgery and Burns
Renal Services including Renal Transplantation
Oral and Maxillofacial surgery
Homeopathy
Queen Elizabeth National Spinal Injuries Unit
3. WEST OF SCOTLAND ADULT HAEMOPOIETIC STEM CELL TRANSPLANT SERVICE
The West of Scotland adult haematopoietic stem cell transplant service (HSCT) is JACIE and HTA accredited. It is currently provided from 2 sites by three teams. The Adult Bone Marrow Transplant Director is Dr Grant McQuaker.
This post will be part of the Transplant team providing allogeneic services and the majority of autologous transplants from outwith Glasgow. It is currently based at the Beatson, West of Scotland Cancer Centre, but will move to the new South Glasgow Hospital (new SGH) in summer 2015. There are 2 additional teams one (Western Infirmary team) also based at the BWoSCC supporting North Glasgow and some surrounding health boards and one (SGH team) based at the Southern General Hospital (SGH) supporting south Glasgow and Clyde.
A review of allogeneic transplant service provision for Scotland reported in 2012 and recommended that all in patient adult HSCT services should be concentrated in Glasgow. However, Scottish government policy is that, wherever possible, care should be provided locally. The service is, therefore, currently being reconfigured to provide pre and post transplant care for the whole of Scotland with the development of new methods of working, including virtual clinics by video link and outreach clinics, as well as protocols for shared local care, support for transplant education nationally, a more responsive pre transplant planning process and an increased consultative role at consultant level. This post is to help with the current workload.
The stem cell collection services are provided by the Clinical Apheresis Unit (CAU) based in the BWoSCC, but run by the Scottish National Blood Transfusion Service (SNBTS), under Dr Kenny Douglas, Consultant Haematologist. This service counsels allogeneic family and unrelated donors prior to stem cell collection as well as coordinating and collecting patients for autologous harvest for the local autologous programme. The CAU also has an active extracorporeal photopheresis and plasma exchange programme
The Stem Cell Processing Service is provided by Greater Glasgow and Clyde as part of Laboratory Services, with Dr Andy Clark as Laboratory Medical Director, and Dr Susan Graham as Laboratory Director. It is based in the new Laboratory building on the GGH campus and provides services for both the adult and children’s transplant programmes.
Tissue typing (H&I) is also provided by GG&C and is based on the GGH campus in the new laboratory building. It is led by Consultant Scientist, Dr Ann-Margaret Little. In addition to the HSCT service it supports the heart and renal transplantation services based in Glasgow. The service is EFI accredited.
There is a weekly joint meeting with representatives of all the above disciplines where all potential transplant candidates referred to the service are discussed. Communication with the referring teams is carried out via email with the referring teams after this meeting in ‘real time’.
The adult allogeneic transplant programme commenced in 1980 and has transplanted over 900 patients. It has 4 full time consultants, excluding this post, and one 0.5WTE university appointee, who will stop providing support after the move to the new SGH. In addition, it currently supports the in-patient haemato-oncology patients from the Glasgow Royal Infirmary (GRI) catchment area as well as providing the adult allogeneic service and majority of the autologous transplant service. The unit has had national designation for all Scottish alternative donor transplants since 2007. The cord programme was initiated in 2009 and has now carried out 15 transplants. It is led by Dr Andrew Clark, who is a member of the UK cord GIAS group.
The Clinical and Processing services are supported by a full time Quality Manager, Robert Boyd, who oversees all quality aspects of the programme.
The transplant team is co-located in the BWOSCC with the Western Infirmary team in 3 wards with 37 in patient beds, all HEPA filtered, 19 single beds, 2x 4 bed bays and 1x 2 bed with 4 designated TYAC beds and dedicated facilities. It will move to the new SGH where there will be 34 haematology beds with 24 for transplantation.
Activity
Allogeneic services are currently provided as follows
- Alternative donor – National service for Scotland from 2007
- Sibling – all Health Boards in Scotland except for Lothian, Borders, Fife and Grampian
Year / Sibling / VUD / Cord / Total
2010 / 10 / 26 / 2 / 38
2011 / 18 / 32 / 2 / 52
2012 / 13 / 37 / 2 / 52
2013 / 9 / 44 / 1 / 54
2014 / 23 / 60 / 2 / 85
Autologous services are provided for Ayrshire & Arran, Dumfries & Galloway, GG&C, Forth Valley, Lanarkshire and some patients from Highlands and Islands Health Board.
Year / Transplant team / WI/Stobhill team / SGH team / Total2010 / 57 / 19 / 5 / 81
2011 / 36 / 15 / 8 / 61
2012 / 44 / 24 / 12 / 81
2013 / 53 / 23 / 6 / 83
2014 / 41 / 18 / 13 / 72
- Haematology in Greater Glasgow and Clyde
The managerial structure for haematology is split between the Diagnostics directorate for laboratory issues and service and Regional Services directorate for all aspects of clinical haematology including anti-coagulant services, haemophilia, bone marrow transplantation and haemato-oncology. There is joint job planning between the two directorates.
The provision of clinical haematology services for Greater Glasgow and Clyde is currently under review, and it is likely that the configuration described below will change with the opening of the new South Glasgow Hospital (new SGH) in 2015, which will have 34 in patient haematology beds and a reduction in service provision at the BWoSCC to 19 beds. The transplant services will be moving to 24 beds based at the new SGH.
Gartnavel General Hospital - The Haematology department at GGH provides liaison haematology services for the surgical and medical services including infectious diseases and respiratory medicine. The haematology laboratory provides specialist services for stem cell processing and immunophenotyping. In addition the consultants provide laboratory and liaison support for the Golden Jubilee Hospital which houses all the cardiology and thoracic services for the West of Scotland.
Beatson, West of Scotland Cancer Centre - This based on the Gartnavel General Campus site. It is Scotland’s largest cancer centre, and the largest in the UK based on activity. It is co-located with the Paul O’Gorman Leukaemia Research laboratory.
The centre has 170 beds in 9 wards (3 Wards totalling 39 beds are for haemato-oncology). The haematology unit supports in patients for the North of Glasgow and in addition has the Scottish Adult Allogeneic HSCT Service. There is also a large and busy Day Case Chemotherapy Unit comprising 36 treatment stations. The centre has its own out-patient department and a large aseptic facility for cytotoxic reconstitution. The unit has an accredited gene therapy aseptic facility. The Beatson West of Scotland Cancer Centre (BWoSCC) is superbly equipped with 11 linear accelerators.
Glasgow Royal Infirmary (GRI) - This will be the main acute hospital for North Glasgow following the closure of Stobhill and Western Infirmary in patient beds. It has the regional haemophilia unit and provides BCSH level 1 care for the local population. All patients requiring intravenous chemotherapy or specialist nursing care are transferred to the BWoSCC for management by the specialist teams at that site.
Southern General Hospital (SGH) - The Haematology department at SGH provides in patient clinical haematology services to BCSH level 3. Inpatients are admitted to ward 24 which has 14 dedicated haematology beds. The laboratory and liaison service supports a very busy acute hospital with a number of specialist services including the Institute for Neurosciences. There is a large new laboratory build. This houses all histopathology, cytogenetics and molecular pathology for GG&C.
New South Glasgow Hospital This will open in 2015 to replace the SGH and is a capital building project. The building is completed and will be handed over in February 2015. It will provide acute medical services for south Glasgow as well as specialist services for GGC. There are 1019 single rooms with a planned 10 in patient haematology beds for South Glasgow, and 24 for Bone Marrow Transplantation.
Stobhill - This is a new purpose built facility with day case surgery, out patients, imaging and a satellite haematology laboratory supported by GRI. There is a haematology day case area, but this does not provide intravenous chemotherapy.
New Victoria (Vic) - This is a new purpose built facility with day case surgery, out patients, imaging and a satellite haematology laboratory supported by SGH. There is a large haematology/ oncology day case area which supports the SGH in patient service.
Royal Alexandra Hospital (RAH), Paisley - The Haematology department at RAH provides clinical haematology services to BCSH level 2a with a busy day patient and outpatients. Inpatients are admitted to ward 1 which has 18 beds shared between Clinical Haematology and Rheumatology/General Medicine. Adult patients requiring more intensive therapy are transferred to either SGH or BWOSCC.
Inverclyde Royal Hospital (IRH), Greenock - The Haematology department at IRH provides a day patient, outpatient and laboratory service as well as providing liaison haematology for medical and surgical specialties on site. Patients with disorders requiring more intensive in patient care will be transferred to the combined inpatient unit at RAH or SGH or BWoSCC depending on clinical requirements.
Vale of Leven Hospital (VOL), Alexandria - The Haematology department at VoL provides a day patient, outpatient and laboratory service as well as providing liaison haematology for medical and surgical specialties on site together with general practitioners in the area. Patients with disorders requiring more intensive in patient care will be transferred to the combined inpatient unit at RAH or SGH or BWoSCC depending on clinical requirements.
Greater Glasgow Clyde will have consultant post at the following sites after the opening of the new SGH
New South Glasgow Hospital
Transplant teamSouth Glasgow Team
Dr Grant McQuakerDr Alastair Hart
Dr David IrvineDr Gail Loudon
Dr Andrew ClarkDr Anne Morrison
Dr Anne ParkerDr Ian MacDonald
This post
Glasgow Royal Infirmary Beatson, West of Scotland Cancer Centre
Dr Catherine Bagot Dr Mark Drummond
Dr Louisa McIlwaine Dr Edward Fitzsimons
Dr Campbell Tait Dr Nick Heaney (TYAC consultant)
Prof Tessa Holyoake
Dr Mike Leach
Dr Pam McKay
Dr Richard Soutar (0.5 SNBTS)
Dr Jennifer Travers
Prof Mhairi Copland
Royal Alexandra Hospital Inverclyde Royal Infirmary & Vale of Leven
Dr Alison McCaig Dr Patricia Clark
Dr Alison Sefcick Dr Glenn Rainey
Dr Carol Stirling Vacancy
Dr Audrey Todd
Vacancy
In addition there is
Dr Arif Alvi, Associate Specialist for Haemophilia based at GRI
Dr Leesa Marsh, Staff Grade, based at VoL
Junior Medical Staff
Specialist Trainees – the West of Scotland deanery has 22 numbered posts for haematology with 14-15 based in GG&C adult haematology at any one time
Research Opportunities
Clinical Trials
The Clinical Research Unit at the BWOSCC is the largest of its kind to be funded by Cancer Research, UK. It houses Scotland’s first ever co-ordinating centre for the National Cancer Research Institute. The unit offers support to all clinicians within the BWOSCC to initiate and conduct clinical trials. The unit has a large portfolio of Phase I - III studies across the range of cancer sub-specialties and has a particular interest in the development of first-in-man anti-cancer drugs. It is supported by designated staff and facilities for Phase I/early Phase II clinical trials. The trials unit has been rated alpha-star by external review. Already, at least 11% of the regional cancer centre’s patients are entered into clinical trials.
The BWOSCC is the only Scottish centre for the Leukaemia and Lymphoma Research Trials Acceleration Programme (LLR TAP).
Beatson Institute for Cancer Research
Professor Karen Vousden heads the laboratories at this internationally renowned centre, located 3 miles from the BWoSCC. This initiative, developed in collaboration with Cancer Research UK, offers unrivalled opportunity for collaboration in basic cancer research. The Beatson Institute has undergone a £30 million redevelopment funded by Cancer Research UK and the University of Glasgow. A Translational Research Centre is being built on the Garscube Estate to complete a virtual comprehensive cancer research and treatment centre, given CRUK Centre status in 2011. The Cancer Sciences Division was 4th in the whole of the United Kingdom in the 2009 Research Assessment Evaluation
Paul O’Gorman Leukaemia Research Centre(POGLRC)
The HSCT service collaborates closely with the Paul O’Gorman Leukaemia Research Centre (POGLRC) led by Professor Tessa Holyoake, Professor Mhairi Copland is a member of the HSCT Consultant Team. The POGLRC is part of the Division of Cancer Sciences at the University of Glasgow. The Centre, opened in March 2008, is built on the Gartnavel Hospital campus and has 5 group leaders with interests in CML and leukaemia stem cell biology (Tessa Holyoake), normal and leukaemic stem cell fate and microenvironment (Mhairi Copland), CLL biology and normal lymphopoiesis (Alison Michie), the role of signal transduction in stem cell self-renewal, haemopoiesis and angiogenesis (Helen Wheadon) and paediatric AML (Karen Keeshan). The Centre houses state-of-the-art facilities including a dedicated tissue culture suite, FACSAria cell sorter, FACSCanto flow cytometer, Taqman quantitative RT-PCR, Fluidigm Biomark, and fluorescence microscopy. Additional complimentary facilities are available at the Beatson Institute, including the Beatson Advanced Imaging Resource. The Paul O’Gorman Leukaemia Research Centre has also recently become part of the West of Scotland Cancer Research Centre “WE CAN” – a collaborative initiative between the NHS, CR-UK and all Universities in the West of Scotland to promote cancer research, identify bio-markers and develop novel therapeutics. There are also strong links with the Institute for Immunology, Inflammation and Infection, University of Glasgow.