Colorectal Cancer Delays
Supplementary Table 1. List of ICD-9 codes indicating comorbid conditions of the gastrointestinal tract that were excluded from study sample.
Diagnosis/Symptom / ICD-9 codeCrohn's Disease
Regional enteritis small intestines / 555.0
Regional enteritis large intestines / 555.1
Regional enteritis small intestines with large intestines / 555.2
Regional enteritis unspecified site / 555.9
Colitis of unspecified etiology, Inflammatory Bowel Disease
Ulcerative (Chronic) entero-colitis / 556.0
Ulcerative (Chronic) ileocolitis / 556.1
Ulcerative (Chronic) proctitis / 556.2
Ulcerative (Chronic) proctosigmoiditis / 556.3
Pseudopolyposis of colon / 556.4
Left sided ulcerative (chronic) colitis / 556.5
Universal ulcerative (chronic) colitis pancolitis / 556.6
Other ulcerative colitis / 556.8
Ulcerative colitis unspecified / 556.9
Other and unspecified non-infectious gastroenteritis and colitis / 558.9
Irritable bowel syndrome/diarrhea
Irritable bowel syndrome / 564.1
Colitis mucous* / 564.1, 564.9
Spastic colon / 564.1
Functional diarrhea / 564.5
Diarrhea not otherwise specified / 787.91
Incontinence of feces / 787.6
Diverticulitis
Colon- Diverticulitis (without mention of hemorrhage) / 562.11
Colon- Diverticulitis (with hemorrhage) / 562.13
Diverticulitis of small intestine without hemorrhage / 562.01
Diverticulitis of small intestine with hemorrhage / 562.03
High risk diseases and condition with symptoms similar to CRC
Benign neoplasm of other parts of digestive system- duodenum, jejunum, and ileum / 211.2
Benign neoplasm of other parts of the digestive system- colon / 211.3
Benign neoplasm of other parts of the digestive system- Rectum and Anal Canal / 211.4
Neoplasm of uncertain behavior of stomach intestines and rectum / 235.2
Personal history of malignant neoplasm, gastrointestinal tract unspecified / V10.00
Personal history of malignant neoplasm, large intestine / V10.05
Personal history of malignant neoplasm, rectum rectosigmoid juntion and anus / V10.06
Colonic polyps / V12.72
Anal and rectal polyps / 569.0
Family history of malignant neoplasm of gastrointestinal tract / V16.0
Abcess of intestine (rationale: could be symptom of Crohns, diverticulitis, colitis, etc.) / 569.5
*Code changed between 1998-2005.
Supplementary Table 2. List of ICD-9 codes indicating clinical manifestations, symptoms, and diagnoses suggestive of colorectal cancer in the year prior to CRC diagnosis.
Abdominal pain
Abdominal pain unspecified site / 789.00
Abdominal pain right upper quadrant / 789.01
Abdominal pain left upper quadrant / 789.02
Abdominal pain right lower quadrant / 789.03
Abdominal pain left lower quadrant / 789.04
Abdominal pain periumbilic / 789.05
Abdominal pain epigastric / 789.06
Abdominal pain generalized / 789.07
Abdominal pain other specified site / 789.09
Abdominal pain, swelling, or mass
Abdominal pain, swelling or mass, unspecified site / 789.30
Abdominal pain, swelling or mass, right upper quadrant / 789.31
Abdominal pain, swelling or mass, left upper quadrant / 789.32
Abdominal pain, swelling or mass, right lower quadrant / 789.33
Abdominal pain, swelling or mass, left lower quadrant / 789.34
Abdominal pain, swelling or mass, periumbilic / 789.35
Abdominal pain, swelling or mass, epigastric / 789.36
Abdominal pain, swelling or mass, generalized / 789.37
Abdominal pain, swelling or mass, other specified site / 789.39
Abnormal Stool
Nonspecific abnormal finding in other body substances; stool contents / 792.1
Anal/rectal pain, anal spasm
Anal or rectal pain / 569.42
Anal spasm / 564.6
Anemia
Iron deficiency anemias secondary to blood loss (chronic) / 280.0
Iron deficiency anemia unspecified / 280.9
Acute posthemorragic anemia / 285.1
Anemia unspecified / 285.9
Anorexia or unexplained weight loss
Abnormal loss of weight* / 783.2, 783.21
Anorexia / 783.0
Constipation
Constipation* / 564.0, 564.01
Slow transit constipation / 564.01
Outlet dysfunction constipation / 564.02
Other constipation / 564.09
Fatigue
Other malaise and fatigue* / 780.7, 780.79
Flatulence, eructation and gas pain
Flatulence, eructation and gas pain / 787.3
Observation for suspected neoplasm
Observation for suspected malignant neoplasm / V71.1
Other GI symptoms, other bowel changes
Other symptoms involving digestive system, other change in bowel habits / 787.99
Rectal bleeding or rectal/GI tract hemorrhage
Hemorrhage of rectum and anus / 569.3
Hemorrhage of gastrointestinal tract unspecified / 578.9
Blood in Stool / 578.1
Vomiting or nausea
Nausea with vomiting / 787.01
Nausea alone / 787.02
Vomiting alone / 787.03
*Code changed between 1998-2005.
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