CLUSTAL W (1.82) multiple sequence alignment
Rat TCCT---CATACACTCAGGGATGGGATGATTAGAACATTTGAACTGATGAAGA 50
Mouse CATTTGATCCT---CATACACTCAGGGATGAGATGATTAAAACATTTGAACTGACAAA-- 278
Rabbit CGTTTAATCCTACCCAGCGATTCGGGCT---GACGTTCAGGCCCATT-TGC------366
Human CATTTGATCCT-CACAGAGTCTCAGGGATGAGATTTTTAGGCCCAGTGTACTGATGAGGA 414
**** ** ** ** ** * * * * *
Rat G---ACTGTTCTGACCCGCCCAGGGTT----ACTGAGCT--CTGCATGCGGAAGCCAGAT 101
Mouse -----CTGTTCTGACCTGCCCAGGGTT----GCTGAGCT--CTGCATGCTGAAGCCACAT 327
Rabbit ----GCTGCTGAGACCCGCCCCAGGTT----GCTGGA------ACCAAAACCAT-- 406
Human AACTGCTGTTGAGACTTGCCCAAGGTTCTTGGCCGGAGCGCTTCAGCACTGAAACCAA-- 472
*** * *** **** **** * * * ** ***
Rat ACTAACCACGTTGCTTCAGT----GATTTAGCCCTT---TTCCTGTTTCTGTATTAATGT 154
Mouse ACTAAACTCTTTGCTTTAGT----GATTTAGCGCTT---TTCCTGTTTCTATATTAATAT 380
Rabbit -CTGTGCGCCTTGACTCAGG--AGGATTCTGGACTCAAGTCCTTGTTTCCGTCTTGATCT 463
Human -AGTTGTCTCTACCCTTGGTCTAGGATTCTAGACTCATGTTCTTGCTTCTGTATTGCTAA 531
* * * **** ** * * ** *** * ** *
Rat AGAATGATTAAACAGAGGCCCGGCCTCAACTCGCCAAGGTATTTAGATAGGAGCCTACTC 214
Mouse AGAATGATTAAACAGAGGCCTGGCCTCAACTTGCCAAGGTATTTAGATGGGAGTCTACTC 440
Rabbit GAAACGGTTGAGTGGAGGCCTGGCCTCAGCTCCCAGAGGTGCTGGATTGAGTGTCCTCCC 523
Human GGAATGGTTGGGAGCGG--CTGGC-TCAGCTCCTTGAGGTCCTGAGCTGAGTGTCTGCTC 588
** * ** * * *** *** ** **** * * * * * * *
Rat CTGAGTTGCATCCACA------CCCCACCACTCGGTGTTGTGACTTTGAAAGCTGCAGG 267
Mouse CTGAGGTGCA------CCCCACTACAC--TGTTGTGGCTTTGAAAGCCGCAGG 485
Rabbit CCACCCTACCCCTCAGGAC-TGCTCCCAACACCCCCCGGGC------ACAGACCTCCCGG 576
Human CCATGGTGTCCCCCCACACATACCATGTACACACCTTGTCCTGACCTAGAGAGTCCTGAG 648
* * ** * * * * *
Rat GAACAAGGCCTCCAGGG-AGTGGCTCAAGGGTTTGGGCACTGAGTCAAACTTGGCATAGT 326
Mouse GAACAAGGGCTCGAGGG-AGTGGCTCAGGGGTTAGGGCAATGAGTCAACCTTAGCATAGT 544
Rabbit AAGGGGGGAGGAAAGGGGAGTGGCTCAGGGCTTAGCGCACTGAGTCAAACCTGGTTGGGT 636
Human TGGTGGTGGGGGGAGGGGACTGGCTCAGGGGTTAGGGCACTGACTCAAACCTGGCTGGGT 708
* **** * ******* ** ** * *** *** **** * * * **
Rat GAGGGAAGATGGT--GACTGATTAAAACGAGAAGAGTGTAGCAAA-CCAGGCATTTTTCT 383
Mouse GGGAAAAGAGGGT--GACTGGTTAAAAGAAGAAGAGTGTAGCAAAACCAGGCACTTTCCT 602
Rabbit GGGGAAAGAGAAA--AACTGGAAC-AAGGAGA-GAGTGTGACAGA----GGCATTTTTCT 688
Human GGGGAGAGAAAGATTGATTAAAGCTAGGGAGA-GAGTGTGACAAA----GGCATCCTACT 763
* * *** * * * *** ****** ** * **** * **
Rat GTTTCATGGGAATCTGCCTGGGCACACATGTGCTCACATGC-CCCGCCC--CTGGAAACC 440
Mouse GCTTCACTGGAATCTGCC-GGGCACACGTGTGCTCACATGC-CCCGCCC--CTTGAAGCC 658
Rabbit GGTTCTCTGGGATCTGCCTGGGACCACACGGGCTCCCACACATCCGGCAAGCTCAGGGCC 748
Human GGTTCTCTGGGATCTGCCTGGGCCCACATGTGCTCACACACGTCCGGACAGC-CAGGGCC 822
* *** ** ******* *** *** * **** ** * *** * **
Rat CCGCCTCTTCTTGTATCCCAGGTG--ATACACAAA----CACTCTCAGAGTGTAGCCCTT 494
Mouse ACTCCTCTTCTTGTATCCTAAGTG--ATACACAAA----CAGTCCCCAAGTGAAGCCCTT 712
Rabbit CTGCCCCTTCCCGCACCCAAAGCATTGTGCGCAAGCACCCAGCCCTGAAGCGAAGGCCTT 808
Human CTGCCC-TTCCCGTATCTGCAGTG--ATGCACAAATCCGCAGCCCCTGCACAAAGCCCTC 879
** *** * * * * * * *** ** * ** ***
Rat TGGCTGACCCACCACATACCTGCCTTGAATTTTGGTTTCCAGTGGTATGTGTTGGAAGTG 554
Mouse TGGCTGACCCGCCACACACCTGCCTTGAATTTTGGTCTTCATTGCTATGTGTTAGAAGT- 771
Rabbit TGGCTGCCCTGCTT-----CCCACCTGC-CTGGAGTTTTGATTGATAT-TGGTG------855
Human TGGCTGACCTGCCTGGAAGTTTATATCCACTGGTGTGTCTACTGAGGG-TGTTG------932
****** ** * * * ** * * ** ** *
Rat GCACAAATCCTGAGTAGGTTCCAGGGCTTGCCAGCTGAACAGGGGGGGAAAACTCACACA 614
Mouse ------CTGC-TAGGTTCCAAGGCTTGCCAGCTGAACAGGGA---AAAACTCACACC 818
Rabbit ------CTGTGCCGGAGGT-GGGGCATGCCCC 880
Human ------GAG-GTGGGGCAC-CTGCCCCACCCC 956
* ** * * *
Rat ATGCTTACTTAGTCTGTCGGCTTTCTTCTGTAATCCCAGCAACTGGGAGGCTGAAGCAGG 674
Mouse ATGCTTACT------GTCAGCCTTCTTCTGTAATCCCAGCACTTGGGAGGTTAAAGCAGG 872
Rabbit TTGCCAG------ATCTTGAGGCTTGG--AGCTGGACTAAA 913
Human CGGGCAG------GTTCTGGTGCTTGG--AGCTGGACAAGA 989
* * *** * * * *
Rat AGGATTACCGTGAGCTCAAAGTCTACCTGGGCTCTATGTGAGACCATTTCGAAACAAACC 734
Mouse AGAGTTACTGTGAGCTCAAAGTCTGCCTGGGCTATATGTGAGATCATTTCAAAACAAACA 932
Rabbit GAAAGCA---TGGG------TGGGTACGGCCCC------937
Human AAAGGCAGTGTGGG------TGTGGAGGGCTCC------1016
* ** * * * *
Rat AAAAA------AGTCAGTGTCTATGTAGATCCTGGAGC 766
Mouse AAAAACAAAAACAAACAAAAAAACCAAACAACCAATCAGTGTATATGTAGATCCTGGAG- 991
Rabbit ------CGGCACGT-CCTGGAGCCTGTG-- 958
Human ------CTGCCAGTTCCTGGGGCCTCTC-- 1038
* * * * * ***
Rat TTCTGTTCTTACTCCCCAAGATACCTATGTACAGGATACATTTCCAAACAGGTTGCTGCC 826
Mouse --CTGTTCCTACTTCCCTGGATACCTTTGTACAGGATACATTTCCAAACAGATTGCTGCC 1049
Rabbit ---T---CCCACTCC--GAGGCACCTCCCTGCCTGCCACATCTCCAAGCAGCCTCTCCTG 1010
Human ---TGTCCCCACTCCCCACGGCACCTCCCTGCCTGATGCATCACCAAACAGCCCCTCCTG 1095
* * *** * * **** * * * *** **** ***
Rat AAGTATGCTGCTTTGTCTTGTTGCTGCTGCTGTTGTCGTTGTTGCCAAATCCTATT---- 882
Mouse TAGGATGCTGCTTTGTGTCTGTCTTTCTTTTCTTTTCTTTTCTTTTCTTTTCTTTTCTTT 1109
Rabbit CGGTCTGCTTATAGGGGTC------TTGTCG------1035
Human GATTCTGTTTCCTTGTGTC------TTCTTGTCAGCCTGTTTTTACTGT---- 1138
** * * * ** *
Rat -----TTCACTATCTTTGATCATGGCCCACAGATAGAGCTAAAAT------922
Mouse TCTTTTTCTTTCTTTTTTTTTTTTTTTTTTTGCCAATGCTATTTTCACTATCTTTGATGG 1169
Rabbit ------CGGTCCCTGGGCAGAGCTGGGAC------1058
Human ------CTTCTGCTAGGCGGCCCATGGGCAGAGCTGGGAC------1172
* * ***
Rat --ACCAATGGGATGGAGTGGGGAG------CCCTGACTG-----GCGGTGCCACG 964
Mouse TGGCCCATGGAGCGGAGTGAAGAGG------TCCTAGTTGTCGGTGCGGTGCCTCG 1219
Rabbit ---CCTAGTGGGTGGAGGGGAAAGC------GCCCTGGCTG-----ATGGGCTCAGG 1101
Human ---ACTAGTGGGAAGGAAGGAAAGAAGGAAGAAGGCCCTGTCTG-----ACGGGCCTGAG 1224
* * * * * ** *** ** ** *
Rat GACAGGGCCAGAGAGAGAGCCTCCCTAAAGATGTCTGGC-TCTTC---TCTGCCTTGGGG 1020
Mouse GACAGGGCCAGAGAGAG--CCTCCCTAAAGCTGTCTGGC-TCCTC---TCTGCCTTGGGG 1273
Rabbit GGCA------GCCTCC------GTGCTCGGCCTCCTC---TCTGCCTCAGG- 1137
Human GACAAGACCCAAGGAGA-GCCTCCCTGAAGATGCCTAGCCTCCTCCTCTCTACCTTGGGA 1283
* ** ***** ** ** ** ** *** *** **
Rat CTGTTTTAATGACATCTCTGAAGGTTCACCCAGAACT------GGAGCTGCGAAGTACAG 1074
Mouse CAGTTTTAATGACATCTCTGACGGTTCACCCAGAGCCAGGGCAGGAGCTGGAAAGGACAG 1333
Rabbit TTGTCT--GTGCCATCACTGGTGTCTCTCCCAGAGCTGGGGGTGGAGCTGGGATGCACAC 1195
Human TCGCCTTGGTGCCATCCTCAGTGTTTC-CCCAGTGTCGGGG-TGGAGTAAGGATGCACAC 1341
* * ** **** * ** ***** **** * * ***
Rat AGGGTAGGTTCCTGGAGCCGGTCAGTCTGGATTCTCAGGAAGAATTCCAGGCTGCAAATG 1134
Mouse AGAGTGTGTTCCTGGAGCCGGTTGGTCTGGATTCTCAAGAAGAATTCCAGGCTGCAAATG 1393
Rabbit AGGGCAGGTGCTTGTAGCTGGTTGGTCTGGATTCCCAGGAGGAATTCCAGGCTGGAAAAG 1255
Human AGCACAGGTGCCTG-AGCCGGTTGGTCTGGATTCCCAGGAAGAATTCCAGGTTGGAGAAA 1400
** ** * ** *** *** ********** ** ** ********** ** * *
Rat AGGGGAAATGCTCACCTCCAGCTGATGAGACAGTCTCAGG-GAAAGAAGGGAACACCAGG 1193
Mouse AGGGGAAATGCTTACCTCCAGCTGATGAGACACTCTCAGT-GAAAGAAGGGAATACCAGG 1452
Rabbit AGGTGGGATCTTGGACTC------CAGACCTTCCCCTC--TGAGAGGA---TACTCTG 1302
Human AGGGAATCCTCTAGTCCAA--CTGAGCAGAGACTCCTCTCAGTGAGAGAAAGGTACTCTG 1458
*** * * *** ** *** ** *
Rat TAGCCTGGGGAGGAGGCCCC--TGTCCACCCAGGTCTGAACACAAG----GACCTAAGCC 1247
Mouse TAGCCTGGGGAGGAGGCTCC--TGTCCACCCAGACCTGAAAGCAAGCCAAGACCTAAGCC 1510
Rabbit CAAGTGGGGGAGGAGGCCCCC-TTCCCACCGACTCCTGTGTGCAAA----GACCTAAGC- 1356
Human TACCCCTGGAAGGGGGACTCAGTTCCCACCCAAGCCTGAGTGGAAA----GGCCTAAACA 1514
* ** *** ** * * ***** * *** ** * ***** *
Rat TTCCCAAAAC------TTGCAA----GCTGGGAGGGGGAAACAAGACATCATTTCTCTT 1296
Mouse TTCCCGAGAC------TTTCAA----GCTGGGAGG------1535
Rabbit ------CTGCAG----GCTGGGGGACAGAAA-ACAAGGTTGCCTCTACC 1394
Human TCCCCTAACCCCCGAGGCTACAGCGGGGGTGGGGGACGTGAA-ATGAGATTGCTCCTACT 1573
* ** * **** *
Rat GTGACCCCCTTAATCTCAAACTTAGAAGGACCAGAGGGACAG----CCCACTCATACTGG 1352
Mouse ------ATCTCGAACTTAGAAGAAACAGAG--ATAG----CCCACTCATTCTGG 1577
Rabbit CCGACCCCCTTCATTACAAACTCAGGAGATGTGAGGAGCTAGGGGTTGTTCTCGTCCTGG 1454
Human CTGATCTCCCTAATCCCAAACT------TGAGGGCAGCTCA------CTCATGCCTG 1618
** * **** *** * * *
Rat GGGCTGTGGAACAACTAGACACAGA--GACAGATGGGGGTGTAGTATGCCGAGAGGCGTG 1410
Mouse GGGCTGTGGAACAGCT-GAAAGAGA--GACAGA--AGGGTGCAGTATGCTGAGGGGCATG 1632
Rabbit GGGCTGTGGAGCAGCTGGAAGAAA---GACAGATTGGGGGGGGG------GGGGTTTGTC 1505
Human GGGCTGTAGAGCAGCTGAGAAAGAAGGGACAGACTTGGGGGTGG------AGGG--AGTC 1670
******* ** ** ** ****** *** * * * *
Rat AGAAGACCCGGTAGAGCTGGCTGGTCAGGGACTGGCAGGTGGAGCCAGTTTGAGAGCCTG 1470
Mouse AGAAGACCTGGTAGAGCTGGCTGGTCAGGGACTGACAGGTGGAGCCAGTTTGAGGGCCTG 1692
Rabbit AGAA-ATCTGGTAGAGCCGGCAGGTCAGGAGCCGSSTGGTGGAGCCAGTCTGAGGGCCTG 1564
Human AGAATATCTGGTAGAGCCAGCAGGTCAGGGGTTAGCTGGTGGAGCCAGTCTGAGGGCCTG 1730
**** * * ******** ** ******* ************ **** *****
Rat GATGCTGATGTCATCTGTCTGCAGCCCTGAGGTGCTGGGACCTTCCTAGGCAAAAGGAGT 1530
Mouse GCCGCTGATGTCATCTGTCTGCAGCC-TGAGGTACTGGGACCTTCCTAGGCAAAAGAAGT 1751
Rabbit GCTGCTGATGTCACCAGCCAGCAGC--TGGGATGT-GGGACCTCCCTGGGCAGGATAAGT 1621
Human GCTGCTGATGTCACCAGTCTGCAACC-TGGGATCCCAGGACCTCCCTGGGCAGGATGAGT 1789
* ********** * * * *** * ** * * ****** *** **** * ***
Rat TC------CAGTCCAAGGGACCAGTTTCACCAGGCCAAGCCTGGTGAGTGCTGCAAGA 1582
Mouse TC------CAGTCCCAGGGACCAGTTTCACAGGGCCAAGCCCGGTGGGTGCTACAAGA 1803
Rabbit TTTGCAGGGCCAGGCTCATGGGCCAGTTTCACAGGGCCACGCCTGGCTTGGGCTGTGAGG 1681
Human TC--CAGGACCAGGCCCCTGGGCCAATTTCATAGGGCTGAGCCTGGCTTGGGCTGCACAG 1847
* *** * ** *** ***** *** *** ** * ***
Rat CAG-----CTTGTCAGCAGGGCCCTGTGAGAACAAAAGTATGCATCTCCAGCTTGGAAAC 1637
Mouse GAG-----CTTAGCAGCAGGGCCCTCTGAGAGCAAAAGGAGGCATCTCCAGCTAGGGAAC 1858
Rabbit CAGCTGGCCTTGGCAGCAGGGGCCCATGGAAGCAGAGGTAGGCAGTCTGAACCTGTGAAC 1741
Human AA------CTCGGCAGCAGGAGCCTGTGAGAGCAGAGGTAGGCAGCCTAAGCTTGGGACC 1901
* ** ******* ** ** * ** * * * *** * * * * *
Rat A--ATCTGCCCTACAGGGCTGTGAGTGGAAGAAGATCCCTTCTCTTTTGCTCTCTGAACA 1695
Mouse AG-ATCTGCCCTGCAGGCCTG--AGTGGAAGAG---CCCTTCTCTTT-GCTCTCTGAACA 1911
Rabbit AGGAGGAGGCCCGCAGGATGG-----GG------CTGTCCCATTGCTTCTC---ACA 1784
Human AGAAGG---TCGGCCAGACAG-----GG------CTGTGG-GTGGAAGGGC---CTG 1940
* * * * * * ** * * * *
Rat CCTAGTGTGGCAAGAATCAAATTGGTATGGGATCTGTCACCAAACACCTTCCCTTTTTAC 1755
Mouse CCTAGTGTGGTAAGAATCAAGTTGGTGTGGGATCCGTCACCAAACGCCTTTCCTTTTCAC 1971
Rabbit CGT-GTGCGTTCACCACAGGA-CTGGGT------CTTCTCAAAGCCCTGCATCTTCAC 1834
Human CCT-GCCCCACTGCCCTTGCAGCTTCTT------CATCCGGGAGAAGGGGCTCCTCAC 1991
* * * * * * * **
Rat CTCAGCCCCAGGTCTGACAGAACTTTGACTGGGACCATCCCCCCCCCAACCCCCCAGCAT 1815
Mouse TTCAGCCTCAGGTCTGACAGAACTTTGATCCGGACCCCCTCCTT------AGCAT 2020
Rabbit CCTGCC------TCAGCCCAGACCCTGGCCCGCCCCC------AGCGT 1870
Human ATGCCCA----GTCTGGTAGGAATCAGCCTGGTGCCA------GGGGC 2029
* ** * * * * ** *
Rat GACCTCAGTTCCTAGAAAGGAGAAGGTGGGTGG----AGTCAGACTTTCCCGTCCCTAC- 1870
Mouse GACCTCAGTTCCTAGAAAGGAGAAAGTGGGTGG----AGCCAGTCTTTCCCGCCCCTAC- 2075
Rabbit CA--TCAGTTCCTCGAAAGGGGAAGGGGGTGGGCC---GTCCCCATTTCCTGCCCCTATC 1925
Human CA--TCACAGCGGTGGCTCCCACCAAAGCCCAGCCTAAGCCCCCAGACCTCACCCCTGCT 2087
* *** * * * * * * * ****
Rat -CAGGGGACAGCCCCCAGAGACTGGCCTC--TTGACAGG--AGGGATGAAGCAACT-ATC 1924
Mouse -CAGAGGACAGCCCCCAGAGACTGGCCTC--TTGACAGG--AGGGATGAAGCAACC-CTC 2129
Rabbit TCATGAGACAGCCCCCAGAGGCCGAGCAC--TTCCCTGCCTGGGGATGGAGCAACCGAGC 1983
Human CCCT------CCCTAGCATCTTCTCCCCATTTCCCGCCCAGAGGCCTGGCC-TCTTCT 2138
* *** ** * * * ** * * * * **
Rat TTCCCTTTTTCCCAGAAGCTCAGCCCCGCC-TCCCCTCCCCTCATAAACTACTCACG-GA 1982
Mouse TTCCCCTTTTCCCAGAAACTCGGCCCCGCC-TCCCCTCCCCTCATAAACTGCTTACCCGG 2188
Rabbit TTCCCCTTCTTCCAGGACCTCGGCCCCGCCCTCCCCACCCCTCATAAACCACCTCCCTGG 2043
Human CTCCGCCCCCTACAGCAGTTTGGCCCCTCCCTCCCCA-----CATAAGTCACTTACCAGG 2193
*** *** * * ***** ** ***** ***** * * *
Rat CCCGCCC-TACACCTTCCA 1999
Mouse CCCGCCC-TACACCTTCCA 2201
Rabbit CCCGGCCC-ACATCTTCCA 2051
Human TCTGTCCCTGCGGCATCCA 2208
* * ** * ****