CHEM 327-2T: Intermediate Organic Chemistry, Fall 2017
Instructor: Dr. Uttam Pokharel Office: 137 Beauregard
Phone: 985-448-4504 e-mail:
Course Meeting: Tuesday 09:00 am-9:55 am (BEA 248)
Thursday 09.00 am-11.50 am (BEA 244)
Office Hours: 11:00 – 12:00, (MW), 10:00 – 12:00 (T), 1:00 – 4:00 (TR)
Whenever I am in the office you are welcome to come in and ask questions.
Catalog Description: CHEM 327. Intermediate Organic Chemistry. 2-1-3. Prerequisite: CHEM 226. Continued laboratory study of the properties, preparation, and analysis of organic compounds. Experimental reports incorporate scholarly organic chemical literature as a primary source. (40.0504)
Prerequisites: CHEM 226
Required Texts and Other Materials:
1. Organic Chemistry, Second edition by David Klein
2. Safety Goggles—Approved by instructor available in Bookstore
3. Notebook—bound, duplicating notebook with tear out sheets. Available in Bookstore
RECOMMENDED BOOKS: Spectrometric Identification of Organic Compounds, 8th edition by Silverstein, Webster, Kiemle and Bryce.
Organic Chemistry 2nd edition by Jonathan Clayden; Nick Greeves; Stuart Warren
A course website is set up on the Nicholls MoodleTM server (http://moodle.nicholls.edu/moodle/). You will find a copy of this syllabus, handouts and some of the PowerPoint presentations used in this class.
Course Goals: The student will develop an understanding of and employ proper techniques used in organic synthesis, data collection, product analysis, and documentation. The student will also develop skills in chemical literature search and critical analysis of relevant chemical literature.
Student Outcome Objectives:
At the end of this course the student will be able to
· Perform single-step and multiple-step synthesis of organic compounds using standard laboratory procedure.
· Extract and purify of organic compounds by common laboratory techniques like column chromatography, recrystallization and solvent extraction
· Understand the chemistry of carboxylic acids derivatives, amines, carbonyl compounds, and aromatic compounds.
· Select appropriate physical and spectroscopic technique to characterize organic compounds they synthesize.
· Understand the working principles of infra-red spectroscopy, column chromatography, gas chromatography, mass spectrometry, UV-Vis spectroscopy, 1H NMR, 13C NMR, DEPT, H-H COSY, HMQC, and develop hand-on experience.
· Identify unknown organic compounds based on their spectroscopic data.
· Prepare scientific reports using standard scientific terminologies.
· Make critical analysis of published journal article on chemical sciences.
Lecture Schedule:
Date / Topic8/22 / UV-Vis spectroscopy
8/29 / IR and MS
9/5 / NMR
9/12 / 1H, 13C NMR
9/19 / DEPT, COSY, HMQC
9/26 / Fall Break 1
10/3 / Exam 1
10/10 / Alpha carbon chemistry
10/17 / Alpha carbon chemistry
10/24 / amine
10/31 / amine
11/6 / Introduction to organometallic compounds
11/13 / Introduction to organometallic compounds
11/20 / Thanksgiving holiday
11/27 / Introduction to organometallic compounds
12/5 / Exam 2
Lab Schedule:
Date / Experiment8/24 / Check –in, Safety and UV vis spectroscopy
8/31 / IR and MS
9/7 / NMR
9/14 / Preparation of synthetic banana oil
9/21 / Characterization of banana oil by IR, 1H NMR and COSY
9/28 / Separating the components of analgesic tablet
10/5 / Multistep synthesis (literature sources)
10/12 / Multistep synthesis (literature sources)
10/19 / Fall Break 2
10/26 / Multistep synthesis (literature sources)
11/2 / Multistep synthesis (literature sources)
11/9 / Multistep synthesis (literature sources)
11/16 / Multistep synthesis (literature sources)
11/23 / Thanksgiving holiday
11/30 / Multistep synthesis (literature sources)
COURSE CONTENT:
Lab Performance and Report: Your understanding of the experiments is reflected from your performance. It is your responsibility to understand the working principles of the experiments. I will regularly monitor your understanding by asking relevant questions whenever appropriate. Your points will be deducted if you violate safety rules inside the laboratory. Lab performance and attendance constitute 20 points.
You need to prepare a lab report after finishing each experiment in typed format. The due date will be typically at the beginning of next experiment. You need to prepare lab report in given format. The report should be concise, and should reflect important observations and their discussions. Lab report constitutes 20 points.
Exams. There will be two exams. The first exam will cover spectroscopy and second exam covers the other chemistry topics.
Homework: Homework will be assigned from chemistry class advantage site. You will be working with published research articles in the assigned general topics of chemistry. I will help you on getting access of them in class.
Grading
Item / % weightLab performance + Lab report / 20% + 20% = 40%
Exams / 20% + 20% = 40%
Homework / 20%
Total / 100%
Method of Evaluation:
A straight percentage is used to determine grade.
A = 90 - 100% B = 80 - 90% C = 70 - 80% D = 60 - 70%
Make-up Policy:
No make-ups are allowed for the experimental or discussion portion of the class. Late laboratory reports will be deducted 5 points per day (including weekends).
Attendance Policy:
Attendance is mandatory. This is a laboratory class. You must be present to complete the requirements.
Academic Honesty Policy: Any student found cheating, including plagiarism, will be subject to the penalties as stated in the Student Code of Conduct handbook; including but not limited to a score of zero on exam, review or report, expulsion from the class or expulsion from the University.
Semester Withdrawals: The last day to withdraw from the class with a “W” is 27th October 2017.
Academic Disabilities Policy: If you have a documented disability that requires assistance, you will need to register with the Office of Disability Services for coordination of your academic accommodations. The Office of Disability Services is located in Peltier Hall, Room 100-A. The phone number is (985) 448-4430 (TDD 449-7002).
Academic Grievances. The proper procedure for filing grade appeals or grievances related to academic matters is listed in Section 5 of the Code of Student Conduct and at he following link: http://www.nicholls.edu/documents/student_life/code_of_conduct.pdf .
Continued Learning following an Extreme Emergency:
In order to make continued learning possible following an extreme emergency, students are responsible for:
§ reading regular emergency notifications on the NSU website;
§ knowing their Blackboard (or designated system) student login and password;
§ knowing how to use and access Blackboard (or university designated electronic delivery system);
§ being familiar with emergency guidelines;
§ evacuating textbooks and other course materials;
§ contacting faculty regarding their intentions for completing the course.
Faculty are responsible for:
§ their development in the use of the Blackboard (or designated) software;
§ having a plan for continuing their courses using only Blackboard and email;
§ continuing their course in whatever way suits the completion of the course best, and being creative in the continuation of these courses;
§ making adjustments or compensations to a student's progress in special programs with labs, clinical sequences or the like only in the immediate semester following the emergency.
Class Disruptions: The use of cellular phones, pagers or any other electronic personal devices is prohibited in class. Any infractions will result in class being dismissed and experiments considered over.
This includes but not limited to
· using your phone as timer—get a watch or I will supply stopwatches if needed,
· going to the hallway while a experiment is ongoing to check on texts.
· texting or calling or receiving incoming calls or texts
· receiving alerts regarding incoming texts or calls
· using phone as alarm system.
Note: This is not a binding contract. This syllabus is subject to change throughout the course.