Chapter 14 Section Review

Answer key

Section Review 14-1

1. Two copies of the X chromosome produces a

human female. 2. One X and one Y chromosome produce a human male. 3. A sperm cell, which contains

either a Y or an X chromosome, determines whether a

child is male or female. 4. Half of the sperm cells that

fertilize eggs carry an X chromosome and half carry a

Y chromosome. Because all egg cells carry an X chromosome, half of all zygotes will be XX and half will be XY. 5. In cystic fibrosis, the deletion of three bases in the middle of a single gene changes the protein’s structure. 6. The father and both daughters show the trait. 7. The father and both daughters carry the allele for the trait. 8. The mother and the son do not carry the allele for the trait. 9. The IA allele leads to the production of the Aantigen. IB leads to the B antigen.

Because both alleles contribute to the phenotype, they

are said to be codominant.

Section Review 14-2

1. A sex-linked disorder is one that is caused by a

defective gene on an X or Y chromosome. 2. A single

recessive allele is expressed in a male when it is

found on the male’s X chromosome. 3. There must

be two copies of the allele, one on each of the two X

chromosomes, for a trait controlled by a recessive

allele to be expressed in females. 4. Nondisjunction

leads to the production of gametes with abnormal

numbers of chromosomes. 5. Klinefelter’s syndrome

6. Down syndrome 7. Turner’s syndrome 8. There

have been no reported instances of babies being born

without an X chromosome. Babies have been born

without a Y chromosome. 9. Her mother either has

hemophilia (two recessive alleles) or carries one

recessive allele for hemophilia. Her father has the

recessive allele and hemophilia. 10. Because the

woman’s father is colorblind, she will carry one

recessive allele for colorblindness. Their daughters

have a 100 percent chance of having normal vision,

because they will inherit the dominant allele for normal

vision from their father. Their sons have a 50 percent

chance of being colorblind. They have a 50

percent chance of inheriting the dominant allele for

normal vision and a 50 percent chance of inheriting

the recessive allele for colorblindness.

Section Review 14-3

1. The goal of the Human Genome Project is to analyze

the human DNA sequence. 2. Gene therapy is

the process of replacing an absent or faulty gene with

a normal, working gene in an attempt to cure a genetic

disorder. 3. Modified viruses are often used to

deliver replacement genes. 4. normal hemoglobin

gene 5. genetically engineered virus 6. bone marrow

cell 7. bone marrow 8. DNAsamples from the

victim and the suspect would be compared to the

DNAin the blood. All three samples would be cut

with the same restriction enzymes, targeting small

sections of DNA with little or no known function. The

DNAfragments would be separated by gel electrophoresis. The banding pattern from the individual

that matches the banding pattern for the blood is

identified as the person whose blood was at the scene.

9. Possible student answers may include: An ethical

way to manipulate DNA would be to change DNA to

cure a genetic disease, such as Tay-Sachs or cystic

fibrosis. This application is ethical only if it benefits

humans without harming others. An unethical way to

manipulate DNA might be to clone human beings so

that their organs could be harvested for transplant

recipients.

Chapter Vocabulary Review

1. karyotype 2. sex chromosomes 3. autosomes

4. pedigree 5. nondisjunction 6. d 7. b 8. b 9. a

10. a 11. d 12. A karyotype will show whether or

not a fetus has Down syndrome. 13. Because the X

and Y chromosomes present in the embryo determine

the sex of the child. 14. There are 44 autosomes in a

human diploid cell. 15. A pedigree chart shows how

a trait is passed from one generation to the next.

.

Graphic Organizer

1. Autosomal genetic disorders are caused by abnormal

dominant, codominant, or recessive alleles on the

autosomes. 2. Examples include Phenylketonuria,

Tay-Sachs, Huntington’s disease, Cystic fibrosis, and

Sickle cell disease. 3. Yes (Affects males more often

than females, but can affect females if they inherit

two recessive alleles.) 4. Chromosomal disorders are

caused by nondisjunction during meiosis, which

results in an abnormal number of chromosomes.

5. Down syndrome, Klinefelter’s syndrome, Turner’s

syndrome