Dr. MUHAMMAD YAQUB
Associate Professor
Institute of Chemical Sciences
Bahauddin Zakariya University, Multan-60800
Pakistan
Mobil#0092-308-4758848
E-mail:
Date of Birth: 04-04-1964
Field of Specialization:
· Organic Chemistry
Research Interests:
· Organic Spectrometry
· Organic Synthesis
· Bioactive Molecules
Profile
Dr. Muhammad Yaqub received his early education from Okara and Sahiwal. He got his master and MPhil degree in the subject of Chemistry with specialization in organic Chemistry from the Department of Chemistry, Bahauddin Zakariya University, Multan, in 1991 and Quaid-e-Azam University Islamabad, respectively. He joined BZU in 1995 as Lecturer in organic Chemistry. He was awarded PhD scholarship from HEC Pakistan in 2004 for China and then returned to Pakistan after completion his PhD degree from Institute of Chemical Sciences Chinese Academy of Sciences, Beijing, China in 2008. He resumed his duties at the Department of Chemistry, BZU and was selected as Associate Professor of Organic Chemistry. He has 21 years of postgraduate teaching and research experience at University level to his credit and produced so many Chemistry Graduates and Postgraduates at BS, MSc and MPhil levels. He has supervised 02 PhDs and 22 MPhil students. A significant number of PhD and MPhil scholars are also in progress.
Key Publications:
1. Aminah Hameed, Muhammad Yaqub, Mazhar Hussain, Abdul Hameed, Muhammad Ashraf, Humna Asghar, Quart-ul-Ain, Muhammad Moazzam Naseer, Khalid Mahmood, Muhammad Muddassar, Muhammad Nawaz Tahir and Zahid Shafiq, “Coumarin-based thiosemicarbazones as potent urease inhibitors: synthesis, solid state self-assembly and molecular docking” RSC Adv., 2016, 6, 63886-63894.
2. Maqbool Ahmad, Humayun Pervez, Sumera Zaib, Muhammad Yaqub, Muhammad Moazzam Naseer, Shafi Ullah Khan and Jamshed Iqbal, “Synthesis, biological evaluation and docking studies of some novel isatin-3-hydrazonothiazolines” Royal Society of Chemistry (RSC) Advances., 2016, 6, 60826–60844.
3. Humayun Pervez, Maqbool Ahmad, Sumera Zaib, Muhammad Yaqub, Muhammad Moazzam Naseer and Jamshed Iqbal, “Synthesis, cytotoxic and urease inhibitory activities of some novel isatin-derived bis-Schiff bases and their copper(II) complexe”, Med. Chem. Commun., 2016, 7, 914-923.
4. Aminah Hameed,Zahid Shafiq,Muhammad Yaqub,Mazhar Hussain,Muhammad Ajaz Hussain,Muhammad Afzal,Muhammad Nawaz TahirandMuhammad Moazzam Naseer, “Me3N-promoted synthesis of 2,3,4,4a-tetrahydroxanthen-1-one: preparation of thiosemicarbazone derivatives, their solid state self-assembly and antimicrobial properties”, New J. Chem., 2015,39, 9351-9357.
5. Aminah Hameed, Zahid Shafiq, Muhammad Yaqub, Mazhar Hussain, Hafiz Badaruddin Ahmad, Muhammad Nawaz Tahirb, Muhammad Moazzam Naseer, “Robustness of a thioamide {ÁÁÁH–N–CQS} 2 synthon: synthesis and the effect of substituents on the formation of layered to cage-like supramolecular networks in coumarin–thiosemicarbazone hybrids” New J. Chem., 2015, 39, 6052-6061.
6. Abdul Hameed, Khalid Mohammed Khan, Syeda Tazeen Zehra, Ramasa Ahmed, Zahid Shafiq, Syeda Mahwish Bakht, Muhammad Yaqub, Mazhar Hussain, Antonio de la Vega de León, Norbert Furtmann, Jürgen Bajorath, Hazoor Ahmad Shad, Muhammad Nawaz Tahir, Jamshed Iqbal, “Synthesis, biological evaluation and molecular docking of N-phenyl thiosemicarbazones as urease inhibitors” Bioorganic chemistry, 2015, 61, 51-57.
7. Humayun Pervez, Nazia Manzoor, Muhammad Yaqub, and Khalid Mohammed Khan,” 5-Nitroisatin-derived Thiosemicarbazones: Potential Antileishmanial Agents” Journal of Enzyme Inhibition And Medicinal Chemistry, 2014, 29(5), 628-632.
8. Humayun Pervez, Naveeda Saira, Mohammad Saeed Iqbal, Muhammad Yaqub, Khalid Mohammed Khan, “Synthesis and biological evaluation of some N 4-aryl-substituted 5-fluoroisatin-3-thiosemicarbazones”, Medicinal Chemistry Research, 2013, 22(12), 5878-5889.
9. Muhammad Yaqub, Ruqayia Perveen, Zahid Shafiq, Humayun Pervez and Muhammad Nawaz Tahir “Regioselective, catalyst free, one step synthesis of ABCD fused heterocyclic ring system, closely related to circumdatin alkaloids”, Synlett. 2012, 1755-1758.
10. Humayun Pervez, Muhammad Ramzan, Muhammad Yaqub, Faiz-ul-Hassan Nasim and Khalid Mohammed Khan, “Synthesis and Biological Evaluation of Some New N4-Aryl Substituted 5-Chloroisatin-3-thiosemicarbazones’’, Medicinal Chemistry, 2012, 8, 505-514.
11. Muhammad Aslam Shad, Haq Nawaz, Muhammad Yaqub, and Beena Yousuf, “Phytochemical composition and antioxidant properties of rhizomes of Nilumbo Nucifera”, J. Med. Plant Res., 2012, 6, 972-980.
12. Humayun Pervez, Naveeda Saira, Mohammad Saeed iqbal, Muhammad Yaqub, and Khalid Mohammed Khan “Synthesis and Toxicity Evaluation of Some New N4-Aryl Substituted 5-trifluoromethoxyisatin-3-thiosemicarbazones” Molecules, 2011, 16, 6408-6421. 2
13. Pervez, H.; Ramzan, M.; Yaqub, M.; Khan, K. M. “Synthesis, cytotoxic and phytotoxic effects of some new N4-aryl substituted isatin-3-thiosemicarbazones”. Lett. Drug. Des. Discov., 2011, 8 452-458. 2
14. Humayun Pervez Nazia Manzoor Muhammad Yaqub Faiz-ul-Hassan Nasim Khalid M. Khan Synthesis and biological evaluation of some N4-substituted 5-nitroisatin-3-thiosemicarbazones. Med Chem Res 2011, DOI 10.1007/s00044-011-9745-7. 1
15. Humayun Pervez, Nazia Manzoor, Muhammad Yaqub, Ajmal Khan, Khalid Mohammed Khan, Faiz-ul-Hassan Nasim and Muhammad Iqbal Choudhary “Synthesis and Urease Inhibitory Properties of Some New N4-Substituted 5-Nitroisatin-3-thiosemicarbazones” Letters in drug Design & Discovery, 2010, 7, 102-108.
16. Rauf A., Liaqat S., Qureshi A. M., Yaqub M., Rehman A. U., Hassan M. U., Chohan Z. H., Nasim F. H., Hadda T. Ben, “Synthesis, characterization, and urease inhibition of 5-substituted-8-methyl-2H-pyrido[1,2-a]pyrimidine-2-4(3H)-diones”, Med. Chem. Res. 2012, 21(1), 60-74.
17. Muhammad Yaqub, Yu Chu-Yi, Jia, Yue-Mei, Huang Zhi-Tang, “Reactions of Heterocyclic ketene aminals with baylis-hillman acetates: A novel synthesis of tetrahydropyridine-fused 1,3-diazaheterocycles”, Synlett, 2008. 1357-1360.
18. Chohan Z.H., Arif M., Shafiq Z., Yaqub M., Supuran C. T., “In vitro antibacterial, antifungal & cytotoxic activity of some isonicotinoylhydrazide Schiff's bases and their cobalt(II), copper(II), nickel(II) and zinc(II) complexes”, Journal of Enzyme Inhibition And Medicinal Chemistry”, 2006. 21. 95-103. 35.
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