Authors: Mcewan P, Bennett H, Ward T and Bergenheim K

Supplementary figure 2(a-g):

Title: Refitting of the UKPDS 68 risk equations to contemporary routine clinical practice data in the UK

Authors: McEwan P, Bennett H, Ward T and Bergenheim K

Corresponding author: Hayley Bennett

Email:

Address: Health Economics & Outcomes Research Ltd,

Singleton Court Business Park,

Wonastow Rd, Monmouth, UK, NP25 5JA

Telephone: +44 2920 399 146

Number of tables and figures: 3 tables and 2 figures

Number of supplementary tables and figures: 7 tables and 8 figures

Figure S2a: Receiver operator characteristic curves associated with myocardial infarction events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.

Figure S2b: Receiver operator characteristic curves associated with stroke events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.

Figure S2c: Receiver operator characteristic curves associated with congestive heart failure events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.

Figure S2d: Receiver operator characteristic curves associated with ischaemic heart disease events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.

Figure S2e: Receiver operator characteristic curves associated with end stage renal disease events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.

Figure S2f: Receiver operator characteristic curves associated with blindness events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.

Figure S2g: Receiver operator characteristic curves associated with amputation events from refitted coefficients (solid line), UKPDS 68 (long dash) and UKPDS 82 equations (short dash). Left plot = low-risk cohort, right plot = intermediate-risk cohort.