Additional File 3. Predicated Female Targets of Female-Specific Mirnas by Using Mrna And

Additional file 3. Predicated female targets of female-specific miRNAs by using mRNA and EST deposited in the GenBank

Name of miRNA / Length / Best matched target / Function of Best
Matched Target / Species / Mfe (kcal/mol) / P-value / Total number of target
female-miR-395-5p / 21 / gi|256861451 / large subunit ribosomal protein 9 / Acrostichus sp. / -47.5 / 0.000001 / 348
female-miR-018-3p / 23 / gi|324524171 / CCR4-NOT transcription complex subunit 2 / Ascaris suum / -32.5 / 0.00312 / 15
female-miR-250-5p / 22 / gi|324518841 / OV-17 antigen / Ascaris suum / -31.9 / 0.000244 / 20
female-miR-298-3p / 20 / gi|324516803 / 39S ribosomal protein L32 / Ascaris suum / -29.6 / 0.007979 / 33
female-miR-151-5p / 23 / gi|324519747 / OV-16 antigen / Ascaris suum / -36.4 / 0.000628 / 253
female-miR-426-5p / 22 / gi|324523560 / 60S ribosomal protein L18 / Ascaris suum / -29.5 / 0.003796 / 3
female-miR-148-5p / 22 / gi|393911853 / hypothetical protein LOAG_01869 / Loa loa / -35.9 / 0.000025 / 245
female-miR-020-5p / 20 / gi|324543164 / Onchocystatin, partial / Ascaris suum / -42.8 / 0.000002 / 35
female-miR-253-3p / 21 / gi|324513508 / Serine/threonine-protein phosphatase 4 catalytic subunit 1 / Ascaris suum / -31 / 0.003472 / 7
female-miR-311-5p / 22 / gi|324501014 / Leucine-rich repeat-containing protein 68 / Ascaris suum / -30.8 / 0.003905 / 24
female-miR-428-5p / 23 / gi|324513975 / Glycogen synthase kinase-3 / Ascaris suum / -29.8 / 0.002562 / 10
female-miR-308-5p / 24 / gi|324507603 / U2 small nuclear ribonucleoprotein B / Ascaris suum / -32 / 0.000886 / 14
female-miR-059-5p / 24 / gi|364782217 / cytoplasmic beta-actin / Sparus aurata / -36.5 / 0.000314 / 44
female-miR-406-3p / 23 / gi|324548154 / ATP synthase lipid-binding protein, partial / Ascaris suum / -30.9 / 0.004567 / 9
female-miR-422-3p / 20 / gi|324501435 / Unknown / Ascaris suum / -36 / 0.00012 / 202
female-miR-164-3p / 22 / gi|324523867 / Zinc transporter ZIP10, partial / Ascaris suum / -30.6 / 0.003037 / 10
female-miR-122-5p / 24 / gi|324523752 / 40S ribosomal protein S30 / Ascaris suum / -38.6 / 0.000369 / 508
female-miR-293-5p / 20 / gi|324505581 / Acetyl-coenzyme A synthetase / Ascaris suum / -32.1 / 0.001414 / 145
female-miR-365-3p / 24 / gi|324514256 / Growth factor receptor-bound protein 2 / Ascaris suum / -33.7 / 0.00093 / 49
female-miR-448-3p / 22 / gi|324507909 / Protein RER1 / Ascaris suum / -37.5 / 0.00018 / 561
female-miR-011-5p / 22 / gi|170572350 / hypothetical protein Bm1_02890 / Brugia malayi / -30.4 / 0.003779 / 122
female-miR-210-5p / 22 / gi|341888064 / hypothetical protein CAEBREN_06566 / Caenorhabditis brenneri / -31.4 / 0.002035 / 82
female-miR-019-5p / 21 / gi|319656152 / NADH dehydrogenase subunit 5 (mitochondrion) / Ascaris lumbricoides / -33.3 / 0.000184 / 60
female-miR-105-3p / 22 / gi|324515284 / Phosphoserine phosphatase / Ascaris suum / -30.4 / 0.003065 / 6
female-miR-208-5p / 22 / gi|339232481 / beta-tubulin / Parascaris equorum / -33.9 / 0.000611 / 263
female-miR-016-3p / 22 / gi|324507310 / Solute carrier family 25 member 46 / Ascaris suum / -35.4 / 0.000085 / 88
female-miR-198-5p / 23 / gi|312075760 / activated protein kinase C receptor RACK1 / Loa loa / -33.8 / 0.000279 / 16
female-miR-397-5p / 22 / gi|393907532 / hypothetical protein LOAG_10124 / Loa loa / -31.9 / 0.000081 / 191
female-miR-159-3p / 20 / gi|312065232 / hypothetical protein LOAG_00102 / Loa loa / -28.5 / 0.008019 / 15
female-miR-125-3p / 23 / gi|324511886 / Deoxyhypusine hydroxylase / Ascaris suum / -44.2 / 0.000002 / 66
female-miR-354-3p / 22 / gi|308486041 / hypothetical protein CRE_21222 / Caenorhabditis remanei / -31.9 / 0.002055 / 189
female-miR-161-5p / 23 / gi|324533459 / Cysteine-rich protein 1 / Ascaris suum / -37 / 0.000239 / 145
female-miR-364-3p / 23 / gi|324517212 / Phosphoglycerate kinase, partial / Ascaris suum / -34.8 / 0.001371 / 91
female-miR-222-5p / 23 / gi|324516214 / Serine/arginine-rich splicing factor 6 / Ascaris suum / -32 / 0.00295 / 40
female-miR-037-5p / 23 / gi|324503129 / Protein melted / Ascaris suum / -37.6 / 0.000269 / 36
female-miR-171-3p / 24 / gi|33621245 / FMRFamide-related peptide FLP-14 precursor / Ascaris suum / -35 / 0.002279 / 119
female-miR-008-3p / 23 / gi|324553089 / Translationally-controlled tumor protein, partial / Ascaris suum / -34.7 / 0.0008 / 91
female-miR-184-5p / 22 / gi|324505578 / Acetyl-coenzyme A synthetase / Ascaris suum / -31.1 / 0.005705 / 28
female-miR-034-3p / 22 / gi|324504407 / Oxidoreductase dhs-27 / Ascaris suum / -31.1 / 0.004613 / 6
female-miR-239-5p / 22 / gi|1518119 / AsSLR8.97 / Ascaris suum / -32.6 / 0.001698 / 17
female-miR-249-5p / 22 / gi|324503611 / Propionyl-CoA carboxylase alpha chain / Ascaris suum / -31.1 / 0.003886 / 15
female-miR-245-5p / 21 / gi|324509721 / Transmembrane protein 104 / Ascaris suum / -32.5 / 0.001254 / 106
female-miR-230-5p / 22 / gi|312089763 / hypothetical protein LOAG_10792 / Loa loa / -31.3 / 0.002599 / 9
female-miR-301-5p / 23 / gi|321454610 / hypothetical protein DAPPUDRAFT_332869 / Daphnia pulex / -32.5 / 0.003255 / 80
female-miR-289-5p / 20 / gi|324520360 / CDGSH iron-sulfur domain-containing protein 1 / Ascaris suum / -34.3 / 0.000624 / 116
female-miR-431-5p / 23 / gi|170572350 / hypothetical protein Bm1_02890 / Brugia malayi / -34.4 / 0.001005 / 128
female-miR-209-3p / 22 / gi|324499449 / Nuclear anchorage protein 1 / Ascaris suum / -33.8 / 0.001881 / 160
female-miR-123-5p / 23 / gi|170593513 / hypothetical protein Bm1_50200 / Brugia malayi / -39.3 / 0.00009 / 117
female-miR-025-3p / 25 / gi|324512729 / Aminopeptidase, partial / Ascaris suum / -35.7 / 0.001181 / 162
female-miR-104-3p / 21 / gi|324501604 / Unknown / Ascaris suum / -31.9 / 0.002653 / 24
female-miR-267-5p / 23 / gi|324540982 / NADH dehydrogenase / Ascaris suum / -33.3 / 0.001221 / 46
female-miR-399-5p / 22 / gi|324508579 / Elongation factor 1-beta/1-delta 1 / Ascaris suum / -33.7 / 0.001191 / 38
female-miR-118-3p / 22 / gi|324519655 / Small heat shock protein OV25-1 / Ascaris suum / -33.3 / 0.001556 / 18
female-miR-012-3p / 22 / gi|324506691 / Uridine-cytidine kinase-like protein 1 / Ascaris suum / -32.4 / 0.002216 / 851
female-miR-303-3p / 22 / gi|268532508 / Hypothetical protein CBG03224 / Caenorhabditis briggsae / -38.7 / 0.000067 / 692
female-miR-196-5p / 23 / gi|324510642 / Nascent polypeptide-associated complex subunit alpha / Ascaris suum / -33.2 / 0.000944 / 64
female-miR-334-5p / 22 / gi|324520603 / Protein LSM14 A, partial / Ascaris suum / -34.5 / 0.001188 / 363
female-miR-228-3p / 23 / gi|312075760 / activated protein kinase C receptor RACK1 / Loa loa / -29.5 / 0.006293 / 8
female-miR-202-5p / 22 / gi|312071809 / hypothetical protein LOAG_03194 / Loa loa / -34.9 / 0.000639 / 241
female-miR-105-5p / 22 / gi|324520987 / Cuticle collagen 155 / Ascaris suum / -34.6 / 0.000303 / 329
female-miR-193-5p / 21 / gi|324536549 / Homeobox protein, partial / Ascaris suum / -33.6 / 0.000349 / 1172
female-miR-270-5p / 23 / gi|324513762 / Dihydrolipoyl dehydrogenase, partial / Ascaris suum / -34.2 / 0.001062 / 114
female-miR-129-3p / 22 / gi|324518841 / OV-17 antigen / Ascaris suum / -39.3 / 0.000022 / 12
female-miR-224-5p / 24 / gi|324526835 / Ribosome biogenesis protein NSA2, partial / Ascaris suum / -36.1 / 0.000532 / 22
female-miR-258-5p / 24 / gi|324504298 / Glutathione peroxidase / Ascaris suum / -39 / 0.000153 / 214
female-miR-359-5p / 24 / gi|324508837 / Liver carboxylesterase / Ascaris suum / -31.3 / 0.006983 / 13
female-miR-437-3p / 26 / gi|170575389 / hypothetical protein Bm1_08750 / Brugia malayi / -45 / 0.000031 / 150
female-miR-212-5p / 23 / gi|393912006 / hypothetical protein, variant / Loa loa / -35.6 / 0.000738 / 179
female-miR-416-5p / 22 / gi|324566178 / Tubulin beta-1 chain, partial / Ascaris suum / -33.5 / 0.000142 / 190
female-miR-053-3p / 23 / gi|324501697 / KN motif and ankyrin repeat domain-containing protein 1 / Ascaris suum / -34.8 / 0.000596 / 50
female-miR-376-5p / 22 / gi|324508936 / Ubiquitin-like modifier-activating enzyme 5 / Ascaris suum / -36.2 / 0.000442 / 149
female-miR-355-3p / 22 / gi|15277698 / AF395836_1putative chitinase / Ascaris suum / -33.1 / 0.001321 / 227
female-miR-181-5p / 22 / gi|294876044 / Cell wall integrity and stress response component 3 precursor, putative / Perkinsus marinus / -29 / 0.008038 / 3
female-miR-232-3p / 21 / gi|324518251 / Sodium/potassium-transporting ATPase subunit beta-1 / Ascaris suum / -38.1 / 0.000083 / 233
female-miR-281-5p / 20 / gi|156068 / heat shock protein 70, hsp70A2, partial / Brugia pahangi / -32.1 / 0.001104 / 111
female-miR-421-5p / 23 / gi|324519421 / Chondroitin proteoglycan 3 / Ascaris suum / -35.7 / 0.000863 / 221
female-miR-042-3p / 22 / gi|324532788 / 60S ribosomal protein L17, partial / Ascaris suum / -36.8 / 0.000146 / 360
female-miR-271-5p / 21 / gi|324532788 / 60S ribosomal protein L17, partial / Ascaris suum / -31.5 / 0.000986 / 6
female-miR-090-3p / 26 / gi|324521335 / DNA-directed RNA polymerase II subunit RPB3 / Ascaris suum / -34.9 / 0.001433 / 32
female-miR-153-5p / 23 / gi|324501691 / UHRF1-binding protein 1-like protein / Ascaris suum / -33.3 / 0.001393 / 79
female-miR-319-5p / 23 / gi|312074616 / synaptophysin/synaptoporin family protein / Loa loa / -32.5 / 0.001114 / 60
female-miR-257-3p / 22 / gi|170575572 / hypothetical protein Bm1_09120 / Brugia malayi / -35.1 / 0.000185 / 232
female-miR-120-5p / 21 / gi|324517449 / 32 kDa beta-galactoside-binding lectin lec-3 / Ascaris suum / -32.4 / 0.000194 / 67
female-miR-352-5p / 22 / gi|17647231 / calmodulin, isoform A / Drosophila melanogaster / -33 / 0.002066 / 64
female-miR-345-5p / 20 / gi|324522196 / Tubulin beta-1 chain / Ascaris suum / -41.8 / 0.000011 / 854
female-miR-078-5p / 21 / gi|324529442 / Cuticle collagen 19, partial / Ascaris suum / -30.6 / 0.002144 / 39
female-miR-188-5p / 22 / gi|324524208 / Mps one binder kinase activator-like protein1B / Ascaris suum / -35.7 / 0.000183 / 20
female-miR-361-5p / 23 / gi|324512757 / Chaperonin Hsp-60, partial / Ascaris suum / -37.4 / 0.000245 / 396
female-miR-134-5p / 23 / gi|324506599 / Eukaryotic initiation factor 4A / Ascaris suum / -48.2 / 0.000001 / 139
female-miR-388-5p / 22 / gi|324501426 / Myelin expression factor 2 / Ascaris suum / -31 / 0.005295 / 58
female-miR-266-3p / 22 / gi|15277698 / AF395836_1putative chitinase / Ascaris suum / -28.2 / 0.006045 / 17
female-miR-142-5p / 23 / gi|17543714 / Protein VHA-19 / Caenorhabditis elegans / -45.8 / 0.000001 / 143
female-miR-387-3p / 24 / gi|312087465 / hypothetical protein LOAG_09908 / Loa loa / -49.7 / 0 / 359
female-miR-085-5p / 21 / gi|324512597 / IST1 / Ascaris suum / -30.4 / 0.004967 / 18
female-miR-141-5p / 21 / gi|170592033 / Ankyrin repeat / Brugia malayi / -35.8 / 0.000461 / 409
female-miR-312-5p / 21 / gi|324501492 / Protein arginine N-methyltransferase 10 / Ascaris suum / -33.5 / 0.001277 / 45
female-miR-215-5p / 23 / gi|324539266 / Cytochrome c oxidase subunit 3, partial / Ascaris suum / -34.7 / 0.001422 / 210
female-miR-174-5p / 21 / gi|170593055 / Calponin homolog OV9M. / Brugia malayi / -32.3 / 0.001526 / 86
female-miR-028-5p / 22 / gi|193202726 / Protein F32H2.8 / Caenorhabditis elegans / -34.1 / 0.000882 / 86
female-miR-447-5p / 22 / gi|170580960 / PDZ domain containing protein / Brugia malayi / -32.1 / 0.003349 / 44
female-miR-123-3p / 25 / gi|1777779 / cathepsin B-like cysteine proteinase / Ascaris suum / -34.8 / 0.001777 / 103
female-miR-277-3p / 24 / gi|324513600 / Acetyl-coenzyme A synthetase, partial / Ascaris suum / -33.1 / 0.002743 / 39
female-miR-009-5p / 21 / gi|324564529 / Cleavage stimulation factor subunit 2 tau variant, partial / Ascaris suum / -36.2 / 0.000383 / 1202
female-miR-238-5p / 23 / gi|324506558 / N-alpha-acetyltransferase 35, NatC auxiliary subunit / Ascaris suum / -37.6 / 0.00018 / 132
female-miR-264-5p / 22 / gi|221063659 / OV-MSA-1, partial / synthetic construct / -42.2 / 0.000021 / 1062
female-miR-407-3p / 23 / gi|324506684 / Coronin-like protein cor-1 / Ascaris suum / -32.4 / 0.003334 / 35
female-miR-068-5p / 22 / gi|50511745 / MSP-domain protein 1 variant / Ascaris suum / -25.8 / 0.004714 / 1
female-miR-139-3p / 24 / gi|340538989 / cytochrome oxidase subunit I / Contracaecum osculatum / -40.4 / 0.000033 / 53
female-miR-284-3p / 22 / gi|324536071 / Serine/arginine-rich splicing factor 4 / Ascaris suum / -28.4 / 0.000718 / 9
female-miR-206-3p / 23 / gi|324512370 / Thioredoxin-related transmembrane protein 1 / Ascaris suum / -33.5 / 0.000507 / 35
female-miR-373-5p / 20 / gi|324499773 / Acetyl-CoA carboxylase 2 / Ascaris suum / -28.9 / 0.005023 / 2
female-miR-111-3p / 19 / gi|146188305 / phosphofructokinase 1 / Ascaris suum / -29.6 / 0.00007 / 33
female-miR-331-5p / 21 / gi|324564529 / Cleavage stimulation factor subunit 2 tau variant, partial / Ascaris suum / -28.7 / 0.009562 / 5
female-miR-363-3p / 22 / gi|312074683 / hypothetical protein LOAG_04495 / Loa loa / -35.1 / 0.000109 / 315
female-miR-179-3p / 21 / gi|324506691 / Uridine-cytidine kinase-like protein 1 / Ascaris suum / -35.5 / 0.000259 / 206
female-miR-238-3p / 23 / gi|6272123 / 29kDa protein from Anisakis simplex / Anisakis / -39.6 / 0.000131 / 1035
female-miR-292-5p / 23 / gi|324514140 / Fructose-1,6-bisphosphatase isozyme 2 / Ascaris suum / -40.3 / 0.000078 / 412
female-miR-287-5p / 23 / gi|324502030 / Serrate RNA effector molecule / Ascaris suum / -32.6 / 0.000265 / 154
female-miR-306-3p / 23 / gi|256016675 / hypothetical protein / Angiostrongylus cantonensis / -33.1 / 0.000837 / 76
female-miR-388-3p / 23 / gi|159145606 / putative ribosomal protein L4 / Sipunculus nudus / -32.1 / 0.002114 / 30
female-miR-163-5p / 24 / gi|324502491 / Myotubularin-related protein 9 / Ascaris suum / -35.5 / 0.000341 / 51