Supplementary Electronic Table 1
A. Latency to fall (sec) during the rotarod test.
MALE / Saline / Poly(I:C)Speed (rpm) / P40 / P120 / P40 / P120
5 / 57.8 (s = 2.63) / 60.0 (s = 0.00) / 46.0 (s = 10.6) / 60.0 (s = 0.00)
10 / 56.0 (s = 4.55) / 59.5 (s = 0.84) / 24.3 (s = 21.4) / 60.0 (s = 0.00)
15 / 46.8 (s = 3.95) / 33.5 (s = 23.8) / 12.3 (s = 12.5) / 48.6 (s = 18.3)
20 / 38.5 (s = 7.00) / 31.7 (s = 25.3) / 5.00 (s = 4.76) / 39.2 (s = 21.6)
25 / 7.25 (s = 2.22) / 17.5 (s = 23.3) / 3.29 (s = 2.36) / 36.0 (s = 17.2)
30 / 5.75 (s = 0.96) / 18.0 (s = 21.0) / 2.86 (s = 1.95) / 26.4 (s = 19.2)
35 / 2.00 (s = 0.82) / 3.67 (s = 3.20) / 1.29 (s = 1.11) / 10.0 (s = 10.7)
40 / 1.25 (s = 0.96) / 3.50 (s = 3.51) / 0.57 (s = 0.79) / 2.00 (s = 3.94)
FEMALE / Saline / Poly(I:C)
Speed (rpm) / P40 / P120 / P40 / P120
5 / 59.5 (s = 1.00) / 60.0 (s = 0.00) / 47.9 (s = 13.6) / 60.0 (s = 0.00)
10 / 41.5 (s = 15.9) / 60.0 (s = 0.00) / 32.3 (s = 14.7) / 60.0 (s = 0.00)
15 / 33.0 (s = 7.26) / 46.5 (s = 19.8) / 13.6 (s = 8.72) / 26.0 (s = 24.4)
20 / 16.3 (s = 4.79) / 41.8 (s = 24.8) / 7.00 (s = 7.56) / 15.8 (s = 13.2)
25 / 9.50 (s = 5.00) / 28.7 (s = 20.7) / 3.00 (s = 3.07) / 17.2 (s = 17.8)
30 / 5.50 (s = 1.29) / 12.5 (s = 7.66) / 1.63 (s = 1.30) / 9.00 (s = 11.5)
35 / 2.00 (s = 0.82) / 7.50 (s = 9.85) / 1.38 (s = 1.60) / 1.80 (s = 3.03)
40 / 0.75 (s =0.50) / 3.50 (s = 2.59) / 0.25 (s = 0.46) / 2.40 (s = 3.36)
B. Behavioral outcomes in the ladder rung test
MALE / Saline / Poly(I:C)Errors (#) / P40 / P120 / P40 / P120
Half slips / 1.96 (s = 0.54) / 0.80 (s = 0.48) / 3.22 (s = 0.65) / 1.22 (s = 0.47)
Full slips / 1.26 (s = 0.28) / 0.83 (s = 0.28) / 2.96 (s = 0.79) / 1.07 (s = 0.32)
Total misses / 0.59 (s = 0.15) / 0.40 (s = 0.31) / 1.74 (s = 0.40) / 0.89 (s = 0.47)
Total errors / 3.81 (s = 0.60) / 2.03 (s = 0.64) / 7.93 (s = 1.26) / 3.19 (s = 1.17)
FEMALE / Saline / Poly(I:C)
Errors (#) / P40 / P120 / P40 / P120
Half slips / 1.89 (s = 0.62) / 0.71 (s = 0.49) / 2.59 (s = 0.40) / 0.89 (s = 0.33)
Full slips / 1.52 (s = 0.34) / 0.63 (s = 0.63) / 2.15 (s = 0.96) / 0.78 (s = 0.47)
Total misses / 0.56 (s = 0.33) / 0.42 (s = 0.43) / 1.63 (s = 0.54) / 0.96 (s = 0.39)
Total errors / 3.96 (s = 0.86) / 1.75 (s = 0.83) / 6.37 (s = 1.17) / 2.63 (s = 0.73)
C. Time spent (sec) in the chamber containing the social conspecific in the sociability test.
Saline / Poly(I:C)P40 / P120 / P40 / P120
MALE / 137 (s = 20.4) / 127 (s = 53.9) / 69.6 (s = 36.6) / 173 (s = 34.0)
FEMALE / 131 (s = 20.6) / 116 (s = 46.8) / 90.4 (s = 36.6) / 120.7 (s = 41.3)
All P40 and P120 data are shown as mean (standard deviation denoted by s)