Curriculum Vitae
Name: Emmanuel N. MADUAGWU
Sex: Male
Date of Birth: 24-04-1947
Place of Birth: Jos Native town (Northern Nigeria)
State (if Nigerian): Abia State
Nationality (if International Staff):
Marital Status: Married
Number of Children: Seven (7) children
Contact Address:
(Office) (i) Department of Biological Sciences, Covenant University, Canaan Land, Km 10 Idiroko
Rd, OTA, Ogun State
(Residential) (i) Mazi Emma Maduagwu Villa, Amautu-Amise, Umuobila Town, Isuikwuato L.G.A.
Abia State
(ii) House 1A, Close 10, Constitution Road, Satellite Town, Lagos
(iii) Suite 61, Covenant University Campus, Ota, Ogun State
Telephone Number(s): +2348064537688/+2348063993535/+265999570106
E-Mail Address: (i)
(ii)
Educational History:
Section A
Schools/Institutions Attended
S/N / Degree Level / Type / Year / Grade / Institutiona. / Undergraduate. / Biochemistry / 1972 / B.Sc. (Hons.) / University of Ibadan
b. / Postgraduate / Biochemistry / 1976 / Ph.D. / University of Ibadan
c. / Professional / Chemistry / 1982 / Graduate / Royal Society of Chemistry, Russel Square, London
d.
f.
Section B
Technical Quality
S/N / University / Name / From / To / Begin Status / End StatusCovenant University / 2014 / Date / Professor / On-going status
University of Ibadan / 1989 / 2012 / Senior Lecturer / Professor & Head of Department of Biochemistry
University of Ibadan / 1979
1978 / 1981
1979 / Lecturer I
Lecture II / Senior
Lecturer
Lecturer I
University of Malawi College of Medicine / 2002 / 2007 / Professor on Contract / Professor & Head of Department of Biochemistry (2003-2007)
Ladoke Akintola University of Technology, Ogomoso / 1993 / 1995 / Professor & Head of Department on Part-Time attachment from University of Ibadan / Professor & Head of Department on Part-Time attachment from University of Ibadan
Favourite teaching courses and special topics / Nutritional Biochemistry; Biochemical Toxicology; Xenobiochemistry / 1978 / Date / Lecturer II / Professor
Skills and facilities / American College of Toxicologist
Royal Society of Chemistry. London
Institute of Biology, London
Food and Chemical Safety Environmental Action Team-Tropical NGO, P.O. Box 30711, Blantyre, Malawi
Food and Chemical Toxicology Development Initiative NGO, P.O. Box 9922, University of Ibadan / 1979
1985
1985
2005
2011 / Date
Date
Date
Date
Date / Chartered Toxicologist
Chartered Chemist
Chartered Biologist
Consultant
Consultant / Still subsisting
Still subsisting
Still subsisting
Still subsisting
Still subsisting
Still subsisting
Scholarship:
a. The only candidate in the whole of West Africa to obtain a Distinction (A1) in History in the 1962 Cambridge University/West Africa School certificate Examination
b. I have been privileged to hold, simultaneously, the offices of Head of Department, Ag. Dean of Faculty, Ag. College Provost and Stand-in- Ag. Vice-Chancellor in a University setting
c. The Inaugural winner and the FIRST recipient (by open competition and expert assessment) in 1989 of WELLCOME (NIGERIA) Oritsejolomi Thomas Fellowship Award for “distinguished research and publications in Medical Science in Nigeria”
d. One of my research findings on the content of hydrocyanic acid in ‘gari’ was adopted in 1989 by a National Workshop on “Issues of Cassava poisoning’ held at the IITA, Ibadan, Nigeria, to be the National maximum allowable limit of cyanide content of gari
e. Visiting Lecturer, Laboratory of Carcinogen Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, U.S.A (1980)
f. Visiting /Scientist, Fredrick Cancer Research Facility Fredrick, Maryland, U.S.A. (1980)
g. GUEST Scientist, Institute of Toxicology and Chemotherapy, German Cancer research Center, (DKFZ) Heidelberg, West Germany (1981-1982)
h. United Nations University Senior Fellow, Mycotoxins Research Laboratory, Tropical Development and Research Institute (Formerly Tropical Products Institute), London (1985-1986)
i. Consultant Toxicologist to Federal Institute of Industrial Research, Oshodi, Lagos, Nigeria(1980-1982)
j. Invited in 1981 by the Postgraduate Institute of Medical Research & Training (PIMRAT), College of Medicine, University of Ibadan, to become a member of the following:
Ø Expert Cancer Research Group of the PIMRAT
Ø Expert Nutrition Research Group of the PIMRAT
Ø Expert Committee on Nutritional Requirements and their fulfillment for the then
proposed Training Programme of the United Nations University (UNU) World Hunger Programme, in affiliation with University of Ibadan.
k. Nominated in 1991 by the Nigeria/IFAD Cassava Project as Head of the Research Sub-Committed on standardization of the production, processing and utilization of root and tuber crops in relation to cyanide content of cassava
l. Invited by an International Non-Governmental Organisation based in Malawi (FACSEAT-TROPICAL) and with the support of the University of Malawi authorities to position the organisation on a sound footing, as their Executive Director on a Consultancy basis
m. Recipient of several Research Grants and Travel Fellowship Awards from distinguished benefactors such as:
Ø Wellcome Nigeria Fund (1980-1983, 1987)
Ø Royal Society of Chemistry (1986)
Ø Bassir-Thomas Biomedical Foundation (1997)
Ø University of Ibadan Senate Research Grant (1983 & 2002)
Ø German Cancer Research Fund (1981)
Ø United Nations University Senior Research Fellow (1985)
Ø University of Ibadan Senate Research Grant (1983)
n. I represented the Pathology & the Basic Medical Sciences Divisions of the College of Medicine, University of Malawi, on the College of Medicine Research and Ethics Committee (COMREC).
o. I was elected Chairman, Division of the Basic Medical Sciences of the College of Medicine, University of Malawi in 2006.
p. I was nominated by the Nigerian Society of Biochemistry and Molecular Biology as the distinguished OLUMBE BASSIR MEMORIAL GUEST LECTURER for the 2011 Annual Conference of the society held at the University of Nigeria, Nsukka, from 30th September – 3rd November, 2011.
q. The first retired member of staff of the Department of Biochemistry, University of Ibadan (famous as the first ever department of biochemistry in the entire African continent) to be offered a Contract Appointment as a Professor of Biochemistry.
r. I was offered and I commenced a Contract appointment as Professor of Biochemistry on the same 1st October 2012 that I retired from the services of the University of Ibadan
s. As Consultant Executive Director & CEO of an International Food and Chemical Safety NGO in Malawi (2005-2007) I presided over the procurement of several grants for the NGO
t. One of the results of my researches that was reported published in a high impact journal was employed by the benefitting scientific Journal, “Annals of Nutrition and Metabolism Vol. 33, 49-56 of 1989”, as its Cover page design
Publications:
· Thesis:
(1) Maduagwu, E. N.: (1976) Nitrosamine Contamination of Some Nigerian Beverages. Ph.D. Thesis. (University of Ibadan)
· Journal Articles:
(2) Bassir, O. and Maduagwu, E.N. (1978) Occurrence of nitrate, nitrite, dimethylamine and dimethylnitrosamine in some fermented Nigerian beverages. J. Agric. Food Chem., Vol. 26, 200-203.
(3) Maduagwu, E.N. and Bassir, O. (1979) Detection of dimethylnitrosamine in a fermented milk product (Nono). Toxicol Lett. (Amsterdam) Vol. 4,169-173. Maduagwu, E.N. Joaquim, K.A. and Bassir, O. (1979) Contamination of some fermented Nigerian beverages by carcinogenic nitrosamines. Trop. Geog. Med., Vol. 31, 283-289.
(4) Maduagwu, E.N. and Uhegbu, F.O. (1986) N-nitrosamines, Nigerian habitual drinks and cancer. Carcinogenesis Vol. 7:149-151.
(5) Maduagwu, E.N. and Bassir, O. (1975) Appearance and disappearance of dimethylnitrosamine during the fermentation of palm sap enriched with some nitrogen compounds. J. Agric. Food Chem. Vol. 27, 60 –63.
(6) Maduagwu, E.N. (1979) Microbial nitrosamine formation in palm-wine: In vitro N-nitrosation by cell suspensions. J. Environmental Pathol. Toxicol., Vol. 2, 1183-1193.
(7) Maduagwu, E.N. (1981) Observations, in vitro, on N-Nitrosation by intracellular extracts of some micro-organisms isolated from palm-wine. Toxicol. Lett. (Amsterdam), Vol. 7, 341-346.
(8) Maduagwu, E.N. (1982) Effects of pasteurization, vitamin C supplementation and ultraviolet irradiation on the nitrosamine content of palm-wine. J. Food Technol. Vol. 17, 598-594.
(9) Fafunso, M. and Maduagwu, E.N. (1990) Effect of wilting on the nitrate and nitrite contents of some tropical leafy vegetables. West African J. Biol. Appl. Chem. Vol. 37, 7-15.
(10) Maduagwu, E.N. and Bassir, O. (1980) Comparative in vivo metabolisms of dimethylnitrosamine in animals of six different species. J. Environ. Pathol. Toxicol. Vol. 4, 229-235.
(11) Maduagwu, E.N. and Bassir, O. (1979) Comparative embryo-toxicity of dimethylnitrosamine in the chicken embryo. J. Agric. Food Chem. Vol. 27 396-398.
(12) Maduagwu, E.N. and Bassir, O. (1980) A comparative assessment of toxic effects of dimethylnitrosamine in six species. Toxicol. Appl. Pharmacol. Vol. 53,211-219. Maduagwu, E.N. and Anosa, V.O. (1981) Hepatoxicity of dimethylnitrosamine in cats and lizards. Toxicol. Lett, (Amsterdam), vol. 9, 41-44.
(13) Maduagwu, E.N., Frank, N., Spiegelhalder, B. and Preussmann, R. (1983) Nitrosamine metabolism in Kwashiorkor rats. Biochem. Pharmacol. Vol, 32, 3577-3581.
(14) Maduagwu, E.N. (1989) Nitrosamine metabolism in protein deficient weanling rats during the process of repletion. Annals Nutr. Metab., Vol. 33, 49-56.
(15) Maduagwu, E.N. (1989) Effects of nutritional status, and sex and strain differences on the excretion of N-nitrosomorpholine in rats. West Afric. J. Biol. Appl. Chem. Vol. 30-37.
(16) Atawodi, S.E. and Maduagwu, E.N. (1990) Excretion of nitrosodiphenylamine in the bile of guinea pigs following a single intra-peritoneal dose. Nigerian J. Biotechnol., Vol. 7, 240-247.
(17) Atawodi, S.E. and Maduagwu, E.N. (1987) Interaction of nitrosodiphenylamine (NDPA) with rat bile. West Afric. J. Biol. Appl. Chem., Vol., 32, 36-39.
(18) Maduagwu, E.N. Ezeonu, F.C. and Olukoshi, E.R. (1989) Nitrate and nitrite metabolism in rats. West Afric. J. Biol. Appl. Chem. Vol. 34, 9-14.
(19) Atawodi S.E. and Maduagwu, E.N. (1990) Pharmacokinetics of biliary excretion of N-nitrosodiphenylamine (NDPA) in animals of different species. Eur. J. Drug. Metab. Pharmacokinetics. Vol. 15, 27-29.
(20) Atawodi, S.E. and Maduagwu, E.N. (1992) Biliary excretion of N-nitrosodiphenylamine (NDPA) in rats of both sexes. Nigerian J. Biochem. 7, 67-74.
(21) Maduagwu, E.N. (1985) N-Nitrosation of quaternary ammonium compounds in vivo in the Wistar rat. Xenobiotica. Vol. 15, 1061 –1068.
(22) Maduagwu, E.N., Acheampong, Y.B. and Adekunle, A.A. (1986) Surface-activity related toxicity of quaternary ammonium compounds: the chick-embryo model. West Afric. J. Biol. Appl. Chem. Vol. 31, 19-25.
(23) Maduagwu, E.N. (1988) Intervention of nitrite in the metabolism of quaternary ammonium compounds. Drug Metab. Disp. Vol. 16, 512-514.
(24) Atawodi, S.E, Maduagwu, E.N., Preussmann, R. and Spiegelhalder, B (1991) Potential of endogenous formation of volatile nitrosamines from Nigerian vegetables and spices. Cancer Lett. Vol. 57, 219-222.
(25) Adekunle, A.A., Maduagwu, E.N., Oke, B. and Ozoya, S. (1988) Michealis-Menten kinetic analysis and toxicity of nonyl dimethylbenzylammonium bromide (ADB-9) in male and female rats. West Afric. J. Biol. Appl. Chem. Vol. 33, 10-15.
(26) Maduagwu, E.N. and Umoh, I.B. (1988) Dietary thiocyanate and N-nitrosation in vivo in the Wistar rat. Annals Nutri. Metab., Vol. 32, 30-37.
(27) Maduagwu, E.N. (1979) Cyanide content of gari. Toxicol. Lett. (Amsterdam.) Vol. 4, 169-173.
(28) Maduagwu, E.N. and Fafunso, M. (1980) Particle size distribution of hydrocyanic acid in gari, a cassava based product. Toxicol. Lett. (Amsterdam) Vol. 9, 41-44.
(29) Maduagwu, E.N.. and Oben, D.H.E. (1981) Effects of processing grated cassava roots by the “Screw Press” and by traditional fermentation methods on the cyanide content of gari. J. Food Technol. Vol. 16, 2299-302.
(30) Maduagwu, E.N. (1983) Differential effects on the cyanogenic content of fermenting cassava root pulp by B-glucosidase and microbial activities. Toxicol. Lett. (Amsterdam), Vol. 15, 335-339.
(31) Cooke, R.D. and Maduagwu, E.N. (1978) The effects of simple processing on the cyanide content of cassava chips. Food Technol. Vol. 13, 299-309.
(32) Fafunso, M. and Maduagwu, E.N. (1983) Effects of processing on the cyanide content of some Nigerian cereals and legume seeds. West Afric. J. Biol. Appl. Chem. Vol. 22-25, 33-38.
(33) Maduagwu, E.N. and Umoh, I.B. (1982) Detoxication of cassava leaves by simple traditional methods. Toxicol Lett. (Amsterdam), Vol. 10, 245-248.
(34) Maduagwu, E.N. and Adewale, A.F. (1981) Loss of hydrocyanic acid and its derivatives during sun-drying of cassava. In (Terry, E.R. Oduro, K.A. and Caveness, F. Eds). Tropical Roots Research Strategies for the 1981’s IDRC Publication No. 163e, Ottawa, Ontario, Canada. P. 149-151.
(35) Maduagwu, E.N. and Umoh, I.B. (1986) Biliary excretion of linamarin in the Wistar rat. Biochem. Pharmacol., Vol. 35, 3005-3006.
(36) Maduagwu, E.N. (1988) Toxicity of linamarin towards chick embryos. Food Sci. Nutr. Vol. 3, 141-144.
(37) Umoh, I.B., Ogunkoya, T.O., Maduagwu, E.N. and Oke, O.L. (1985) Effects of thiamine status on the metabolism of linamarin in rats. Annals Nutr. Metab., Vol. 3, 141-144.
(38) Umoh, I.B., Maduagwu, E.N. and Amole, A.A. (1986) Fate of ingested linamarin in malnourished rats. Food Chem. Vol. 20, 1-9.
(39) Maduagwu, E.N. (1989) Metabolism of linamarin in rats. Food Chem. Toxicol., Vol. 27, 451-459.
(40) Umoh, I.B. and Maduagwu, E.N. (1981) Effect of bipiperidyl mustard (BPM) treatment on the food consumption and weight gain pattern in chicks. Nutr. Rept. International. Vol. 24, 31-37.
(41) Cornelius, J.A. and Maduagwu, E.N. (1986) The possible effects of aflatoxin contamination on the marketing of palm-kernels from West Africa. Int. Biodeterioration Suppl. Vol. 26, 95-101.
(42) Atawodi, S.E., Maduagwu, E.N., Lamorde, A.G., Spiegelhalder, B. and Preussmann, R. (1992) Precusors of N-nitroso compounds in Nigerian Forages. Proceedings National Workshop on livestock and veterinary services. NVRI (Vom) Nigeria, August 1992 pp. 10-20.
(43) Atawodi, S.E., Maduagwu, E.N., Lamorde, A.G., Spiegelhalder, B. and Preussmann, R. (1992) Precursors of N-nitroso compunds in Nigerian forages. Biological mechanisms, Exposures and Cancer Etiology. In [I.K. O’Neil and H., Bartsch Eds) IARCH Technical Report. No. 121, p. 15 IARC Lyon, France.
(44) Atawodi, S.E, Maduagwu, E.N., Preussmann, R. and Spiegelhalder, B. (1993) Preformed volatile nitrosamines in some Nigerian foodstuffs. Food Chem. Toxicol. 31, 853-855.
(45) Ogunnaike, P.O. and Maduagwu, E.N. (1995] Changes in histology and enzyme activities following the ingestion of silver nitrate solution in rat small intestinal tract. West Afric. J. Biol. App. Chem., Vol. 40, 1-8.
(46) Ogunnaike, P.O. and Maduagwu, E.N. (1995): Silver uptake at three sites along rat small intestinal tract. West Afric. J. Biol. Appl. Chem. Vol. 40, 9-12.
(47) Uhegbu, F.O. and Maduagwu, E.N. (1995) Occurrence of nitrosatable amines in some Nigerian medicinal plants. Bull. Environ. Contamination toxicol. Vol. 55, 643-649. (