PART A Single-choice Questions:

1. Therapeutic action for propranolol does NOT INCLUDE B

A. atrial fibrillation

B. A-V block

C. hypertension

D. hyperthyroidism

E. angina pectoris

2. The effect of pilocarpine on eye is B

A. miosis, increase intraocular pressure, accommodation of paralysis

B. miosis, decrease intraocular pressure, accommodation of spasm

C. mydiasis , decrease intraocular pressure, accommodation of paralysis

D. mydiasis , increase intraocular pressure, accommodation of spasm

E. mydiasis , increase intraocular pressure, accommodation of paralysis

3. The correct statement about epinephrine is that C

A. inhibition of CNS is very strong

B. influence on metabolism is weak

C. it can produce tachycardia

D. it is only administered by iv

E. it can only activate a agonist

4. The intoxication of tubocurarine can be antagonized by C

A. atropine

B. adrenaline

C. neostigmine

D. dopamine

E. ephedrine

5. Patients with myasthenia gravis are more effectively treated with C

A. epinephrine

B. propranolol

C. neostigmine

D. atropine

E. pilocarpine

6.β-antagonists can NOT be used in the treatment of B

A.hypertension

B.bronchial asthma

C.tachycardia

D.angina pectoris

E.hyperthyroidism

7. The released norepinephrine is disposed mainly by C

A.the metabolism in the liver

B.enzymatic inactivation

C.reuptake by the neuronal terminal

D.hydrolysis

E. MAO and COMT in the circulation

8. Which of the following drugs can be used in treatment of glaucoma? B

A. neostigmine

B. pilocarpine

C. phentolamine

D. norepinephrine

E. atropine

9. Which one is NOT the mechanism for epinephrine in the treatment of allergic shock? E

A. cardiac stimulation

B. vasoconstriction to increase blood pressure

C. reduce the release of allergic substance

D. bronchial dilation

E. improve microcirculation

10. Which of the following therapeutic projects would be used in the treatment of patient with serious organophosphate intoxication? C

A.atropine + norepinephrine

B.atopine+ neostigmine

C.atropine + pralidoxime iodide

D.atropine + epinephrine

E.atropine + morphine

11. The main route of inactivation of Ach is that D

A.it is destroyed by MAO

B.it is destroyed by COMT

C.it is retaken into the cytoplasm

D.it is hydrolyzed by cholinesterase

E.it is retaken into the vesicle

12. The elevated blood pressure caused by epinephrine may be reversed by B

A.propranolol

B.phentolamine

C.norepinephrine

D.nicotine

E.atropine

13. Atropine has the following effects EXCEPT B

A.mydiasis

B.spasm of accommodation

C.increase intraocular pressure

D.decrease salivary secretion

E.stimulation of CNS in larger dose

14. d-tubocurarine can mainly block B

A. N1-receptor

B. N2-receptor

C. M-receptor

D. β1-receptor

E. β2-receptor

15. Which of the following does NOT belong to muscarinic actions caused by M-receptor activation? E

A. Heart depression

B. Vessel dilation

C. Smooth muscle contraction

D. Glands secretion increased

E. Mydriasis

16.The dilation of bronchial smooth muscle can be caused by D

A. α1 -receptor activation

B. α2 -receptor activation

C. β1 -receptor activation

D. β2 -receptor activation

E. M-receptor activation

17.Atropine can be used as a preanesthetic agent because it can C

A. relax the gastrointestinal smooth muscle

B. stimulate the heart

C. reduce the bronchial secretion

D. dilate the blood vessels

E. excite the CNS

18. Which of the following drugs can be used for diopter examination E

A. Pilocarpine

B. Neostigmine

C. Epinephrine

D. Phentolamine

E. Atropine

19.The major action of norepinephrine is A

A. vasoconstriction

B. pupillary dilation

C. heart excitation

D. smooth muscle dilation

E. CNS stimulation

20. Which of the following is selective β-adrenoceptor agonist C

A. neostigmine

B. epinephrine

C. isoprenaline

D. propranolol

E. phentolamine

PART B Assay Questions

1. Please describe the clinical uses of epinephrine.

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